Development Level

Tbio 24 | 11,445
Tdark 2 | 6,588

IMPC Phenotype

decreased body length 3 | 101
abnormal bone structure 2 | 187
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased total body fat amoun... 2 | 207
increased circulating alkaline... 2 | 122
preweaning lethality, incomple... 2 | 499
abnormal QT variability 1 | 10
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal heart looping 1 | 5
abnormal heart morphology 1 | 162
abnormal lung morphology 1 | 26
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal sleep behavior 1 | 70
decreased circulating glucose ... 1 | 126
decreased circulating triglyce... 1 | 79
decreased lean body mass 1 | 135
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
hyperactivity 1 | 148
increased body length 1 | 32
increased bone mineral content 1 | 108
increased lean body mass 1 | 172
increased total body fat amoun... 1 | 134
preweaning lethality, complete... 1 | 979
short tibia 1 | 97

Disease

Carcinoma 21 | 11,493
ovarian cancer 17 | 8,520
ependymoma 10 | 4,679
group 3 medulloblastoma 10 | 4,104
medulloblastoma, large-cell 10 | 6,241
Intellectual disability 9 | 1,016
osteosarcoma 9 | 7,950
Autosomal recessive predisposition 8 | 1,442
Dull intelligence 8 | 645
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Poor school performance 8 | 645
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
lung cancer 7 | 4,740
psoriasis 7 | 6,694
Bardet-Biedl syndrome 6 | 51
Kidney cancer 6 | 2,613
Polydactyly 6 | 107
atypical teratoid / rhabdoid tumor 6 | 5,112
malignant mesothelioma 6 | 3,232
Breast cancer 5 | 3,578
Ciliopathy 5 | 71
Congenital hypoplasia of penis 5 | 176
Hypertensive disease 5 | 292
Increase in blood pressure 5 | 119
Multicystic Dysplastic Kidney 5 | 52
Obesity 5 | 678
Short stature 5 | 531
glioblastoma 5 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
Bardet-Biedl syndrome 1 4 | 22
Brachydactyly 4 | 156
Electroretinogram abnormal 4 | 95
Hypogonadism 4 | 173
Joubert syndrome 4 | 66
Nystagmus 4 | 317
Pick disease 4 | 1,894
Retinitis Pigmentosa 4 | 226
adult high grade glioma 4 | 3,801
astrocytic glioma 4 | 2,597
breast carcinoma 4 | 1,638
diabetes mellitus 4 | 1,728
oligodendroglioma 4 | 2,850
Astrocytoma, Pilocytic 3 | 3,081
Cancer 3 | 2,499
Cerebellar Ataxia 3 | 304
Cognitive delay 3 | 608
Congenital hypoplasia of ovary 3 | 30
Cystic kidney disease 3 | 26
Epilepsy 3 | 792
Fibrosis, Liver 3 | 32
Global developmental delay 3 | 608
Hypodontia 3 | 81
Hypoplastic ovary 3 | 30
Low set ears 3 | 181
Mental and motor retardation 3 | 608
Nephronophthisis 3 | 80
Polydactyly of toes 3 | 12
Prenatal onset 3 | 139
Radially deviated fingers 3 | 38
Recurrent respiratory infections 3 | 141
Retinal Degeneration 3 | 106
Schizophrenia 3 | 1,160
Seizures 3 | 596
Senior-Loken syndrome 3 | 22
Sensorineural Hearing Loss (disorder) 3 | 284
Small head 3 | 374
Syndactyly 3 | 88
Ulnar polydactyly of fingers 3 | 47
chronic rhinosinusitis 3 | 512
colon cancer 3 | 1,478
group 4 medulloblastoma 3 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
invasive ductal carcinoma 3 | 2,951
nasopharyngeal carcinoma 3 | 1,058
non-small cell lung cancer 3 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
tuberculosis 3 | 2,010
ulcerative colitis 3 | 1,819
Bilateral fifth finger clinodactyly 2 | 110
Broad flat nasal bridge 2 | 236
Craniosynostosis 2 | 74
Curvature of little finger 2 | 110
Delayed speech and language development 2 | 112
Endometriosis 2 | 540
Kidney Failure 2 | 111
Language Delay 2 | 112
Nasal bridge wide 2 | 236
Speech Delay 2 | 112
Speech impairment 2 | 112
Strabismus 2 | 270
Upward slant of palpebral fissure 2 | 75
active ulcerative colitis 2 | 764
adrenocortical carcinoma 2 | 1,428
astrocytoma 2 | 1,146
lung adenocarcinoma 2 | 2,716
pituitary cancer 2 | 1,972
progressive supranuclear palsy 2 | 676
spina bifida 2 | 1,074

Tissue

Endocrine System 26 | 18,159
Female tissues 26 | 17,400
Male tissues 26 | 17,142
Nervous System 26 | 16,725
Urinary Tract 26 | 16,678
Blood and immune system 25 | 16,909
Cardiovascular System 25 | 15,192
Digestive Tract 25 | 17,369
Liver and Pancreas 25 | 16,750
Respiratory system 25 | 16,393
Skin and soft tissues 25 | 17,230

Target Family

Non-IDG 24 | 12,091
Enzyme 1 | 4,145
Transcription Factor 1 | 1,400

GO Component

centriolar satellite 26 | 26
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Bardet-Biedl syndrome 4 protein BBS4 Tbio Non-IDG -1.53435 31.5 200
Progesterone-induced-blocking factor 1 PIBF1 Tbio Non-IDG -1.30666 21.1 209
Sperm-associated antigen 5 SPAG5 Tbio Non-IDG -1.72743 51.4 136
Keratin, type I cytoskeletal 18 KRT18 Tbio Non-IDG -3.05211 1057.8 1953
Centrosomal protein of 290 kDa CEP290 Tbio Non-IDG -2.03755 107.9 152
Centrosomal protein of 131 kDa CEP131 Tbio Non-IDG -1.78486 61.9 82
Paired box protein Pax-2 PAX2 Tbio Transcription Factor -2.68609 492.0 349
Exocyst complex component 7 EXOC7 Tbio Non-IDG -1.80594 64.5 160
Coiled-coil domain-containing protein 13 CCDC13 Tbio Non-IDG 0.52 0.77 66
Coiled-coil domain-containing protein 14 CCDC14 Tbio Non-IDG 0.38 0.36 32