Development Level

Tbio 65 | 11,651
Tchem 4 | 1,388
Tdark 3 | 6,593
Tclin 2 | 612

IMPC Phenotype

preweaning lethality, complete... 8 | 979
embryonic lethality prior to t... 3 | 278
preweaning lethality, incomple... 3 | 499
thrombocytopenia 3 | 56
abnormal embryo size 2 | 220
abnormal gait 2 | 69
decreased body length 2 | 101
decreased bone mineral content 2 | 151
decreased fasted circulating g... 2 | 65
decreased grip strength 2 | 116
embryonic lethality prior to o... 2 | 239
increased lean body mass 2 | 172
increased startle reflex 2 | 112
increased total body fat amoun... 2 | 134
prenatal lethality prior to he... 2 | 87
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal brain morphology 1 | 13
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal eye morphology 1 | 68
abnormal head morphology 1 | 10
abnormal hindbrain morphology 1 | 10
abnormal maxilla morphology 1 | 17
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal pericardium morpholog... 1 | 26
abnormal placenta size 1 | 20
abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
abnormal startle reflex 1 | 15
abnormal tail movements 1 | 12
abnormal testis morphology 1 | 43
corneal opacity 1 | 32
corneal vascularization 1 | 6
decreased bone mineral density 1 | 126
decreased circulating alanine ... 1 | 47
decreased circulating calcium ... 1 | 36
decreased circulating chloride... 1 | 30
decreased circulating phosphat... 1 | 27
decreased coping response 1 | 8
decreased glycosylated hemoglo... 1 | 1
decreased hemoglobin content 1 | 68
decreased large unstained cell... 1 | 11
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased prepulse inhibition 1 | 82
decreased threshold for audito... 1 | 26
decreased total body fat amoun... 1 | 207
edema 1 | 59
embryonic growth retardation 1 | 106
female infertility 1 | 60
hydroencephaly 1 | 14
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating potassiu... 1 | 29
increased circulating sodium l... 1 | 71
increased grip strength 1 | 41
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 36
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased spleen weight 1 | 10
male infertility 1 | 123
mammalian phenotype 1 | 17
narrow eye opening 1 | 12
pale yolk sac 1 | 25
prenatal lethality 1 | 28
prolonged ST segment 1 | 36
small testis 1 | 58
tremors 1 | 39

Disease

Carcinoma 53 | 11,493
ovarian cancer 47 | 8,520
osteosarcoma 42 | 7,950
atypical teratoid / rhabdoid tumor 41 | 5,112
glioblastoma 41 | 5,792
psoriasis 39 | 6,694
medulloblastoma, large-cell 38 | 6,241
lung cancer 36 | 4,740
ependymoma 35 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 31 | 3,291
Cancer 30 | 2,499
malignant mesothelioma 29 | 3,232
non-small cell lung cancer 27 | 2,890
adult high grade glioma 26 | 3,801
Breast cancer 24 | 3,578
lung adenocarcinoma 24 | 2,716
pancreatic cancer 24 | 2,398
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,989
interstitial cystitis 21 | 2,312
invasive ductal carcinoma 21 | 2,951
Astrocytoma, Pilocytic 20 | 3,081
lung carcinoma 20 | 2,843
ductal carcinoma in situ 19 | 1,745
pituitary cancer 19 | 1,972
group 4 medulloblastoma 18 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 18 | 2,955
primitive neuroectodermal tumor 18 | 3,035
Kidney cancer 17 | 2,613
astrocytic glioma 17 | 2,597
spina bifida 17 | 1,074
group 3 medulloblastoma 16 | 4,104
subependymal giant cell astrocytoma 16 | 2,287
breast carcinoma 15 | 1,638
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,962
primary pancreatic ductal adenocarcinoma 14 | 1,109
oligodendroglioma 13 | 2,850
ulcerative colitis 13 | 1,819
colon cancer 12 | 1,478
diabetes mellitus 12 | 1,728
tuberculosis 12 | 2,010
cutaneous lupus erythematosus 11 | 1,057
esophageal adenocarcinoma 11 | 737
cystic fibrosis 10 | 1,696
dermatomyositis 10 | 966
Autosomal recessive predisposition 9 | 1,442
Breast Neoplasms 9 | 445
Liver Cirrhosis, Experimental 9 | 769
juvenile dermatomyositis 9 | 1,187
Atopic dermatitis 8 | 952
Prostatic Neoplasms 8 | 495
Rheumatoid arthritis 8 | 1,191
acute quadriplegic myopathy 8 | 1,158
adrenocortical carcinoma 8 | 1,428
gastric carcinoma 8 | 807
Mammary Neoplasms 7 | 425
Neoplasm Invasiveness 7 | 161
Osteoporosis 7 | 363
Waldenstrons macroglobulinemia 7 | 765
active ulcerative colitis 7 | 764
astrocytoma 7 | 1,146
Cleft lip-palate-ectodermal dysplasia syndrome 6 | 8
Down syndrome 6 | 499
Multiple myeloma 6 | 1,332
Pick disease 6 | 1,894
Schizophrenia 6 | 1,160
aldosterone-producing adenoma 6 | 665
fibroadenoma 6 | 559
pediatric high grade glioma 6 | 1,064
Cardiomyopathy 5 | 116
Chemical and Drug Induced Liver Injury 5 | 195
Crohn's disease 5 | 321
Duchenne muscular dystrophy 5 | 601
Kidney disease 5 | 430
Neoplasm Metastasis 5 | 168
Prostate cancer 5 | 175
active Crohn's disease 5 | 922
medulloblastoma 5 | 720
nasopharyngeal carcinoma 5 | 1,058
Alopecia 4 | 115
Alzheimer's disease 4 | 658
Amyotrophic lateral sclerosis 4 | 451
Animal Mammary Neoplasms 4 | 136
Autistic Disorder 4 | 364
Becker muscular dystrophy 4 | 191
Colorectal Neoplasms 4 | 243
Dilated cardiomyopathy 4 | 56
Gaucher disease type 1 4 | 180
Hypertensive disease 4 | 292
Intellectual disability 4 | 1,016
Liver neoplasms 4 | 130
Mammary Neoplasms, Animal 4 | 136
Stomach Neoplasms 4 | 300
acute myeloid leukemia 4 | 783
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
hereditary spastic paraplegia 4 | 318
limb girdle muscular dystrophy 2A 4 | 213
mucosa-associated lymphoid tissue lymphoma 4 | 484
non primary Sjogren syndrome sicca 4 | 891
primary Sjogren syndrome 4 | 735
sonic hedgehog group medulloblastoma 4 | 467

Tissue

Blood and immune system 73 | 16,909
Digestive Tract 73 | 17,369
Liver and Pancreas 73 | 16,750
Respiratory system 73 | 16,393
Urinary Tract 73 | 16,678
Endocrine System 72 | 18,159
Female tissues 72 | 17,400
Male tissues 72 | 17,142
Nervous System 72 | 16,725
Skin and soft tissues 72 | 17,230
Cardiovascular System 67 | 15,192

Target Family

Non-IDG 62 | 12,091
Enzyme 8 | 4,145
Kinase 3 | 634
GPCR 1 | 408

GO Component

cell-cell adherens junction 74 | 74
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Desmocollin-2 DSC2 Tbio Non-IDG -1.89689 79.7 173
T-cell immunoreceptor with Ig and ITIM domains TIGIT Tbio Non-IDG -1.72549 54.9 142
Tropomodulin-3 TMOD3 Tbio Non-IDG -1.07490 13.0 95
Catenin alpha-2 CTNNA2 Tbio Non-IDG -1.98557 99.5 74
Cell adhesion molecule 1 CADM1 Tbio Non-IDG -2.77749 549.7 479
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PPP1CA Tchem Enzyme -2.17010 139.0 378
Cell division cycle-associated protein 3 CDCA3 Tbio Non-IDG -0.69544 5.16 140
Fibroblast growth factor receptor substrate 2 FRS2 Tbio Non-IDG -2.37203 224.0 344
Nectin-4 NECTIN4 Tbio Non-IDG -2.04277 114.0 151
Poliovirus receptor PVR Tbio Non-IDG -3.43049 2640.6 432