Development Level

Tbio 56 | 11,445
Tchem 14 | 1,598
Tdark 14 | 6,588
Tclin 3 | 613

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 7 | 979
increased mean corpuscular vol... 4 | 92
preweaning lethality, incomple... 4 | 499
abnormal embryo size 3 | 220
edema 3 | 59
abnormal neural tube closure 2 | 46
abnormal retina morphology 2 | 71
embryonic growth retardation 2 | 106
embryonic lethality prior to t... 2 | 278
hyperactivity 2 | 148
increased circulating sodium l... 2 | 71
persistence of hyaloid vascula... 2 | 33
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal embryo turning 1 | 31
abnormal eye morphology 1 | 68
abnormal hair texture 1 | 4
abnormal hindbrain morphology 1 | 10
abnormal lens morphology 1 | 81
abnormal midbrain morphology 1 | 10
abnormal nail morphology 1 | 8
abnormal pericardium morpholog... 1 | 26
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal tail bud morphology 1 | 8
abnormal vibrissa morphology 1 | 25
abnormal vitreous body morphol... 1 | 10
absent vibrissae 1 | 12
cataract 1 | 92
decreased circulating alkaline... 1 | 46
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating total pr... 1 | 49
decreased grip strength 1 | 116
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
hemorrhage 1 | 23
increased blood urea nitrogen ... 1 | 48
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased fasted circulating g... 1 | 76
increased leukocyte cell numbe... 1 | 47
increased startle reflex 1 | 112

Disease

Carcinoma 64 | 11,493
ovarian cancer 43 | 8,520
osteosarcoma 41 | 7,950
medulloblastoma, large-cell 38 | 6,241
glioblastoma 36 | 5,792
psoriasis 32 | 6,694
ependymoma 29 | 4,679
atypical teratoid / rhabdoid tumor 28 | 5,112
adult high grade glioma 24 | 3,801
lung cancer 24 | 4,740
Breast cancer 23 | 3,578
Kidney cancer 23 | 2,613
invasive ductal carcinoma 22 | 2,951
Astrocytoma, Pilocytic 20 | 3,081
Cancer 20 | 2,499
interstitial cystitis 20 | 2,312
subependymal giant cell astrocytoma 19 | 2,287
group 3 medulloblastoma 17 | 4,104
lung adenocarcinoma 16 | 2,716
non-small cell lung cancer 16 | 2,890
oligodendroglioma 16 | 2,850
primitive neuroectodermal tumor 16 | 3,035
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
lung carcinoma 15 | 2,843
Schizophrenia 14 | 1,160
cutaneous lupus erythematosus 14 | 1,057
pancreatic cancer 14 | 2,398
acute quadriplegic myopathy 13 | 1,158
ulcerative colitis 13 | 1,819
astrocytic glioma 12 | 2,597
breast carcinoma 12 | 1,638
ductal carcinoma in situ 12 | 1,745
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
tuberculosis 12 | 2,010
diabetes mellitus 11 | 1,728
gastric carcinoma 11 | 807
group 4 medulloblastoma 11 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
malignant mesothelioma 11 | 3,232
pituitary cancer 11 | 1,972
nasopharyngeal carcinoma 10 | 1,058
Bipolar Disorder 9 | 666
adrenocortical carcinoma 9 | 1,428
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
pediatric high grade glioma 9 | 1,064
Intellectual disability 8 | 1,016
Muscle hypotonia 8 | 571
Obesity 8 | 678
Rheumatoid arthritis 8 | 1,191
juvenile dermatomyositis 8 | 1,187
primary pancreatic ductal adenocarcinoma 8 | 1,109
Attention deficit hyperactivity disorder 7 | 278
Cognitive delay 7 | 608
Duchenne muscular dystrophy 7 | 601
Epilepsy 7 | 792
Global developmental delay 7 | 608
Liver Cirrhosis, Experimental 7 | 769
Mental and motor retardation 7 | 608
colon cancer 7 | 1,478
dermatomyositis 7 | 966
Autistic Disorder 6 | 364
Autosomal recessive predisposition 6 | 1,442
Breast Neoplasms 6 | 445
Dull intelligence 6 | 645
Endometriosis 6 | 540
Hypertension 6 | 396
Kidney disease 6 | 430
Low intelligence 6 | 645
Mammary Neoplasms 6 | 425
Melanoma 6 | 711
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Poor school performance 6 | 645
Seizures 6 | 596
cystic fibrosis 6 | 1,696
non primary Sjogren syndrome sicca 6 | 891
Crohn's disease 5 | 321
Neurodegenerative disease 5 | 414
Pick disease 5 | 1,894
Prostatic Neoplasms 5 | 495
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
chronic rhinosinusitis 5 | 512
primary Sjogren syndrome 5 | 735
spina bifida 5 | 1,074
Acquired scoliosis 4 | 281
Becker muscular dystrophy 4 | 191
Cerebrovascular disease 4 | 238
Coronary artery disease 4 | 268
Curvature of spine 4 | 282
Down syndrome 4 | 499
Endometrial cancer 4 | 311
Glaucoma 4 | 239
Inflammatory bowel disease 4 | 151
Nystagmus 4 | 317
Short stature 4 | 531
Vascular disease 4 | 319
active Crohn's disease 4 | 922
astrocytoma 4 | 1,146
esophageal adenocarcinoma 4 | 737
pancreatic carcinoma 4 | 562

Tissue

Endocrine System 86 | 18,159
Digestive Tract 85 | 17,369
Female tissues 84 | 17,400
Male tissues 83 | 17,142
Nervous System 83 | 16,725
Skin and soft tissues 83 | 17,230
Liver and Pancreas 82 | 16,750
Urinary Tract 82 | 16,678
Blood and immune system 81 | 16,909
Respiratory system 78 | 16,393
Cardiovascular System 76 | 15,192

Target Family

Non-IDG 58 | 12,091
Enzyme 14 | 4,145
Ion Channel 5 | 344
Kinase 4 | 634
GPCR 2 | 408
Transcription Factor 2 | 1,400
Epigenetic 1 | 242
Transporter 1 | 473

GO Component

cell projection 87 | 87
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tyrosine-protein kinase Fer FER Tchem Kinase -1.86307 55.4 414
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 MAGI1 Tbio Enzyme -1.08587 12.0 153
Methylthioribose-1-phosphate isomerase MRI1 Tbio Enzyme -2.37285 221.6 146
Endophilin-A2 SH3GL1 Tbio Non-IDG -2.15479 134.2 257
Transient receptor potential cation channel subfamily M member 2 TRPM2 Tchem Ion Channel -1.34318 25.1 209
Lysosomal-associated transmembrane protein 4B LAPTM4B Tbio Non-IDG -1.90763 86.1 91
Disintegrin and metalloproteinase domain-containing protein 15 ADAM15 Tbio Enzyme -1.87408 84.1 301
Reticulon-4 receptor-like 1 RTN4RL1 Tbio Non-IDG -0.81334 6.43 92
Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial COQ6 Tbio Enzyme -1.26796 18.5 102
Radial spoke head protein 3 homolog RSPH3 Tdark Non-IDG -1.14197 12.4 28