Development Level

Tbio 28 | 11,445
Tchem 6 | 1,598
Tclin 3 | 613
Tdark 2 | 6,588

Collection

Kinase: IDG Consortium (Target... 2 | 125
RFA-RM-18-021 2 | 328
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 6 | 979
abnormal embryo size 3 | 220
abnormal coat-hair pigmentatio... 2 | 64
decreased caudal vertebrae num... 2 | 53
embryonic growth retardation 2 | 106
increased circulating alkaline... 2 | 122
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal eye anterior chamber ... 1 | 9
abnormal retinal inner nuclear... 1 | 8
abnormal retinal outer nuclear... 1 | 3
abnormal sensory capabilities-... 1 | 8
abnormal tail morphology 1 | 25
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hemorrhage 1 | 23
improved glucose tolerance 1 | 79
increased blood uric acid leve... 1 | 5
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating iron lev... 1 | 30
increased granulocyte number 1 | 1
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101
increased total retina thickne... 1 | 4
increased vertical activity 1 | 24
short tibia 1 | 97

Disease

Carcinoma 34 | 11,493
ovarian cancer 26 | 8,520
osteosarcoma 23 | 7,950
glioblastoma 21 | 5,792
atypical teratoid / rhabdoid tumor 20 | 5,112
medulloblastoma, large-cell 19 | 6,241
psoriasis 19 | 6,694
adult high grade glioma 18 | 3,801
ependymoma 16 | 4,679
oligodendroglioma 15 | 2,850
astrocytic glioma 14 | 2,597
lung cancer 13 | 4,740
Breast cancer 12 | 3,578
lung adenocarcinoma 12 | 2,716
Astrocytoma, Pilocytic 11 | 3,081
group 4 medulloblastoma 11 | 1,855
invasive ductal carcinoma 11 | 2,951
malignant mesothelioma 11 | 3,232
pancreatic cancer 11 | 2,398
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
pituitary cancer 10 | 1,972
primitive neuroectodermal tumor 10 | 3,035
Cancer 9 | 2,499
Kidney cancer 9 | 2,613
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
Pick disease 8 | 1,894
acute myeloid leukemia 8 | 783
group 3 medulloblastoma 8 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
lung carcinoma 8 | 2,843
non-small cell lung cancer 8 | 2,890
subependymal giant cell astrocytoma 8 | 2,287
tuberculosis 8 | 2,010
ductal carcinoma in situ 7 | 1,745
interstitial cystitis 7 | 2,312
Down syndrome 6 | 499
breast carcinoma 6 | 1,638
juvenile dermatomyositis 6 | 1,187
primary pancreatic ductal adenocarcinoma 6 | 1,109
Breast Neoplasms 5 | 445
Multiple myeloma 5 | 1,332
astrocytoma 5 | 1,146
cystic fibrosis 5 | 1,696
dermatomyositis 5 | 966
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
progressive supranuclear palsy 5 | 676
ulcerative colitis 5 | 1,819
Amyotrophic lateral sclerosis 4 | 451
Neoplasm Invasiveness 4 | 161
Neurodegenerative disease 4 | 414
Schizophrenia 4 | 1,160
acute quadriplegic myopathy 4 | 1,158
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
medulloblastoma 4 | 720
spina bifida 4 | 1,074
Depressive disorder 3 | 409
Duchenne muscular dystrophy 3 | 601
Epilepsy 3 | 792
Fatigue 3 | 182
Kidney disease 3 | 430
Mammary Neoplasms 3 | 425
Parkinson's disease 3 | 392
Prostatic Neoplasms 3 | 495
Seizures 3 | 596
colon cancer 3 | 1,478
cutaneous lupus erythematosus 3 | 1,057
diabetes mellitus 3 | 1,728
hereditary spastic paraplegia 3 | 318
non primary Sjogren syndrome sicca 3 | 891
Anemia 2 | 365
Arthritis, Juvenile 2 | 126
Atopic dermatitis 2 | 952
Bipolar Disorder 2 | 666
Disease Models, Animal 2 | 155
Distal limb muscle weakness due to peripheral neuropathy 2 | 62
Distal muscle weakness 2 | 62
Frontal bossing 2 | 157
Highly variable severity 2 | 157
Juvenile arthritis 2 | 126
Lissencephaly 2 | 69
Liver cancer 2 | 604
Melanoma 2 | 711
Mental Depression 2 | 333
Microcephaly 2 | 166
Miller-Dieker lissencephaly syndrome 2 | 19
Multiple Sclerosis 2 | 540
Muscle Spasticity 2 | 195
Neuropathy 2 | 261
Polyhydramnios 2 | 108
Respiratory Insufficiency 2 | 132
Short nose 2 | 132
Slow progression 2 | 89
Small nose 2 | 132
Variable expressivity 2 | 157
Waldenstrons macroglobulinemia 2 | 765
adrenocortical carcinoma 2 | 1,428
esophageal adenocarcinoma 2 | 737
fibroadenoma 2 | 559
mucosa-associated lymphoid tissue lymphoma 2 | 484
nasopharyngeal carcinoma 2 | 1,058

Tissue

Blood and immune system 39 | 16,909
Cardiovascular System 39 | 15,192
Digestive Tract 39 | 17,369
Endocrine System 39 | 18,159
Female tissues 39 | 17,400
Liver and Pancreas 39 | 16,750
Male tissues 39 | 17,142
Respiratory system 39 | 16,393
Skin and soft tissues 39 | 17,230
Urinary Tract 39 | 16,678
Nervous System 38 | 16,725

Target Family

Non-IDG 26 | 12,091
Kinase 8 | 634
Enzyme 3 | 4,145
Epigenetic 1 | 242
GPCR 1 | 408

GO Component

cell leading edge 39 | 39
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Junction-mediating and -regulatory protein JMY Tbio Non-IDG -1.26760 21.2 162
Coronin-1B CORO1B Tbio Non-IDG -1.09320 13.6 149
LIM domain-binding protein 1 LDB1 Tbio Non-IDG -2.22623 164.4 206
SH3 domain-binding protein 1 SH3BP1 Tbio Non-IDG 0.00000 168
LIM domain-binding protein 2 LDB2 Tbio Non-IDG -1.58628 38.6 191
Breast carcinoma-amplified sequence 3 BCAS3 Tbio Non-IDG -1.24719 16.2 149
Rho family-interacting cell polarization regulator 1 RIPOR1 Tbio Non-IDG 0.85 0.29 24
Capping protein, Arp2/3 and myosin-I linker protein 2 CARMIL2 Tbio Non-IDG -0.95074 9.07 5
Actin-related protein 2/3 complex subunit 2 ARPC2 Tbio Non-IDG -1.31089 16.9 270
Tubulin gamma-1 chain TUBG1 Tbio Non-IDG -1.32620 20.6 339