Development Level

Tbio 95 | 11,445
Tchem 13 | 1,598
Tdark 7 | 6,588
Tclin 3 | 613

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 14 | 979
increased total body fat amoun... 6 | 134
abnormal bone structure 5 | 187
decreased body weight 5 | 161
increased lean body mass 5 | 172
preweaning lethality, incomple... 5 | 499
decreased bone mineral content 4 | 151
abnormal behavior 3 | 298
abnormal bone mineralization 3 | 38
abnormal retina morphology 3 | 71
decreased total body fat amoun... 3 | 207
impaired glucose tolerance 3 | 75
increased circulating calcium ... 3 | 34
abnormal coat appearance 2 | 31
abnormal cornea morphology 2 | 31
abnormal embryo size 2 | 220
abnormal lens morphology 2 | 81
abnormal seminal vesicle morph... 2 | 114
cardiovascular system phenotyp... 2 | 36
corneal opacity 2 | 32
decreased body length 2 | 101
decreased caudal vertebrae num... 2 | 53
decreased circulating creatini... 2 | 39
decreased circulating glucose ... 2 | 126
decreased circulating triglyce... 2 | 79
decreased lean body mass 2 | 135
decreased lymphocyte cell numb... 2 | 83
decreased mean corpuscular vol... 2 | 79
decreased red blood cell distr... 2 | 41
edema 2 | 59
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
fused cornea and lens 2 | 5
hemorrhage 2 | 23
hyperactivity 2 | 148
improved glucose tolerance 2 | 79
increased bone mineral content 2 | 108
increased circulating sodium l... 2 | 71
increased circulating total pr... 2 | 28
increased mean platelet volume 2 | 45
increased or absent threshold ... 2 | 101
increased startle reflex 2 | 112
increased vertical activity 2 | 24
persistence of hyaloid vascula... 2 | 33
short tibia 2 | 97
tremors 2 | 39
abnormal head morphology 1 | 10
abnormal locomotor activation 1 | 16
abnormal optic disc morphology 1 | 10
abnormal pericardium morpholog... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal skin coloration 1 | 25
abnormal startle reflex 1 | 15
abnormal tooth morphology 1 | 24
abnormal vibrissa morphology 1 | 25
abnormal whole-body plethysmog... 1 | 4
absent pinna reflex 1 | 23
cataract 1 | 92
cyanosis 1 | 7
decreased circulating amylase ... 1 | 28
decreased circulating chloride... 1 | 30
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased circulating sodium l... 1 | 22
decreased fasted circulating g... 1 | 65
decreased neutrophil cell numb... 1 | 42
embryonic lethality prior to o... 1 | 239
enlarged spleen 1 | 41
enlarged uterus 1 | 11
impaired pupillary reflex 1 | 26
impaired righting response 1 | 26
increased anti-nuclear antigen... 1 | 19
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating phosphat... 1 | 26
increased eosinophil cell numb... 1 | 11
increased heart rate variabili... 1 | 7
increased heart weight 1 | 62
increased large unstained cell... 1 | 5
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased red blood cell distr... 1 | 34
limb grasping 1 | 41
microphthalmia 1 | 26
prenatal lethality 1 | 28
prolonged PQ interval 1 | 5
respiratory system phenotype 1 | 2
small spleen 1 | 19
small superior vagus ganglion 1 | 74
stereotypic behavior 1 | 3
thrombocytosis 1 | 27
trunk curl 1 | 16

Disease

Carcinoma 91 | 11,493
ovarian cancer 66 | 8,520
glioblastoma 60 | 5,792
medulloblastoma, large-cell 58 | 6,241
osteosarcoma 55 | 7,950
atypical teratoid / rhabdoid tumor 51 | 5,112
psoriasis 51 | 6,694
ependymoma 46 | 4,679
adult high grade glioma 40 | 3,801
lung cancer 39 | 4,740
Astrocytoma, Pilocytic 35 | 3,081
Breast cancer 35 | 3,578
group 3 medulloblastoma 35 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 33 | 2,955
Kidney cancer 32 | 2,613
oligodendroglioma 32 | 2,850
pancreatic cancer 32 | 2,398
lung carcinoma 31 | 2,843
non-small cell lung cancer 30 | 2,890
primitive neuroectodermal tumor 30 | 3,035
Cancer 29 | 2,499
intraductal papillary-mucinous carcinoma (IPMC) 29 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 29 | 3,291
invasive ductal carcinoma 29 | 2,951
malignant mesothelioma 28 | 3,232
lung adenocarcinoma 24 | 2,716
pituitary cancer 24 | 1,972
subependymal giant cell astrocytoma 23 | 2,287
interstitial cystitis 21 | 2,312
Autosomal recessive predisposition 20 | 1,442
astrocytic glioma 20 | 2,597
breast carcinoma 19 | 1,638
tuberculosis 19 | 2,010
Pick disease 18 | 1,894
cystic fibrosis 18 | 1,696
ulcerative colitis 18 | 1,819
colon cancer 17 | 1,478
ductal carcinoma in situ 17 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 17 | 1,962
adrenocortical carcinoma 16 | 1,428
Down syndrome 15 | 499
Intellectual disability 15 | 1,016
Liver cancer 15 | 604
spina bifida 15 | 1,074
juvenile dermatomyositis 14 | 1,187
Duchenne muscular dystrophy 13 | 601
Schizophrenia 13 | 1,160
astrocytoma 13 | 1,146
diabetes mellitus 13 | 1,728
esophageal adenocarcinoma 13 | 737
primary pancreatic ductal adenocarcinoma 13 | 1,109
Atopic dermatitis 12 | 952
Bipolar Disorder 12 | 666
nasopharyngeal carcinoma 12 | 1,058
group 4 medulloblastoma 11 | 1,855
medulloblastoma 11 | 720
pediatric high grade glioma 11 | 1,064
Dull intelligence 10 | 645
Low intelligence 10 | 645
Mental Retardation 10 | 645
Mental deficiency 10 | 645
Poor school performance 10 | 645
acute quadriplegic myopathy 10 | 1,158
autosomal dominant Emery-Dreifuss muscular dystrophy 10 | 510
non primary Sjogren syndrome sicca 10 | 891
Melanoma 9 | 711
Rheumatoid arthritis 9 | 1,191
cutaneous lupus erythematosus 9 | 1,057
progressive supranuclear palsy 9 | 676
Alzheimer's disease 8 | 658
Amyotrophic lateral sclerosis 8 | 451
Epilepsy 8 | 792
Neurodegenerative disease 8 | 414
Seizures 8 | 596
Skin cancer 8 | 469
acute myeloid leukemia 8 | 783
dermatomyositis 8 | 966
gastric carcinoma 8 | 807
Cognitive delay 7 | 608
Depressive disorder 7 | 409
Endometrial cancer 7 | 311
Global developmental delay 7 | 608
Liver Cirrhosis, Experimental 7 | 769
Mental Depression 7 | 333
Mental and motor retardation 7 | 608
Parkinson's disease 7 | 392
aldosterone-producing adenoma 7 | 665
fibroadenoma 7 | 559
interstitial lung disease 7 | 298
pancreatic carcinoma 7 | 562
Autistic Disorder 6 | 364
Dyspnea 6 | 76
Hypertension 6 | 396
Infantile onset 6 | 238
Large intestine cancer 6 | 126
Osteoporosis 6 | 363
Waldenstrons macroglobulinemia 6 | 765
active ulcerative colitis 6 | 764
posterior fossa group A ependymoma 6 | 468
sonic hedgehog group medulloblastoma 6 | 467

Tissue

Digestive Tract 116 | 17,369
Endocrine System 116 | 18,159
Female tissues 116 | 17,400
Skin and soft tissues 116 | 17,230
Blood and immune system 115 | 16,909
Liver and Pancreas 114 | 16,750
Male tissues 114 | 17,142
Urinary Tract 114 | 16,678
Respiratory system 112 | 16,393
Nervous System 111 | 16,725
Cardiovascular System 106 | 15,192

Target Family

Non-IDG 84 | 12,091
Enzyme 20 | 4,145
Kinase 8 | 634
Ion Channel 4 | 344
GPCR 1 | 408
oGPCR 1 | 421

GO Component

cell cortex 118 | 118
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tyrosine-protein kinase Fer FER Tchem Kinase -1.86307 55.4 414
Nuclear mitotic apparatus protein 1 NUMA1 Tbio Non-IDG -2.76544 575.8 235
Metabotropic glutamate receptor 7 GRM7 Tchem GPCR -2.25415 190.8 304
Small proline-rich protein 4 SPRR4 Tdark Non-IDG -0.32647 2.13 9
Unconventional myosin-VIIa MYO7A Tbio Non-IDG -2.14713 133.5 129
Septin-5 SEPT5 Tbio Non-IDG -1.71017 49.4 178
Unconventional myosin-X MYO10 Tbio Non-IDG -1.49855 36.4 47
Oocyte-expressed protein homolog OOEP Tdark Non-IDG -0.60309 4.20 9
Unconventional myosin-IXb MYO9B Tbio Non-IDG -1.68591 55.7 79
CD302 antigen CD302 Tbio Non-IDG -1.67580 43.9 145