Development Level

Tbio 34 | 11,651
Tclin 18 | 612
Tchem 12 | 1,388

IMPC Phenotype

decreased vertical activity 4 | 208
abnormal behavior 3 | 298
increased heart weight 3 | 62
enlarged heart 2 | 210
improved glucose tolerance 2 | 79
preweaning lethality, incomple... 2 | 499
prolonged QT interval 2 | 38
abnormal eye morphology 1 | 68
abnormal femur morphology 1 | 14
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal retinal blood vessel ... 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal urinary bladder morph... 1 | 11
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased cardiac muscle contr... 1 | 11
decreased grip strength 1 | 116
decreased heart rate 1 | 18
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
enlarged adrenal glands 1 | 3
enlarged kidney 1 | 14
enlarged spleen 1 | 41
enlarged uterus 1 | 11
hydrometra 1 | 53
hyperactivity 1 | 148
increased body weight 1 | 25
increased circulating choleste... 1 | 66
increased fasted circulating g... 1 | 76
increased vertical activity 1 | 24
irregularly shaped pupil 1 | 7
male infertility 1 | 123
polycystic kidney 1 | 15
preweaning lethality, complete... 1 | 979
prolonged PQ interval 1 | 5
prolonged ST segment 1 | 36

Disease

Carcinoma 49 | 11,493
ovarian cancer 40 | 8,520
psoriasis 33 | 6,694
glioblastoma 30 | 5,792
osteosarcoma 30 | 7,950
lung cancer 27 | 4,740
Breast cancer 26 | 3,578
atypical teratoid / rhabdoid tumor 26 | 5,112
medulloblastoma, large-cell 25 | 6,241
group 3 medulloblastoma 24 | 4,104
Cancer 23 | 2,499
adult high grade glioma 21 | 3,801
ependymoma 21 | 4,679
invasive ductal carcinoma 21 | 2,951
diabetes mellitus 20 | 1,728
lung adenocarcinoma 20 | 2,716
malignant mesothelioma 20 | 3,232
lung carcinoma 19 | 2,843
ductal carcinoma in situ 17 | 1,745
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
pancreatic cancer 17 | 2,398
Astrocytoma, Pilocytic 16 | 3,081
Kidney cancer 16 | 2,613
breast carcinoma 16 | 1,638
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
non-small cell lung cancer 16 | 2,890
colon cancer 15 | 1,478
interstitial cystitis 15 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,989
Schizophrenia 14 | 1,160
oligodendroglioma 14 | 2,850
Hypertension 13 | 396
Obesity 13 | 678
primitive neuroectodermal tumor 13 | 3,035
ulcerative colitis 13 | 1,819
Prostatic Neoplasms 12 | 495
Bipolar Disorder 11 | 666
Heart disease 11 | 306
astrocytic glioma 11 | 2,597
Alzheimer's disease 10 | 658
Atrial Fibrillation 10 | 124
Coronary artery disease 10 | 268
Stomach Neoplasms 10 | 300
Vascular disease 10 | 319
subependymal giant cell astrocytoma 10 | 2,287
Arthritis 9 | 290
Depressive disorder 9 | 409
Hypertensive disease 9 | 292
Kidney disease 9 | 430
Liver Cirrhosis, Experimental 9 | 769
Seizures 9 | 596
adrenocortical carcinoma 9 | 1,428
pediatric high grade glioma 9 | 1,064
primary pancreatic ductal adenocarcinoma 9 | 1,109
tuberculosis 9 | 2,010
Asthma 8 | 385
Autosomal recessive predisposition 8 | 1,442
Cerebrovascular disease 8 | 238
Diabetes Mellitus, Experimental 8 | 108
Epilepsy 8 | 792
Lung disease 8 | 142
cystic fibrosis 8 | 1,696
fibroadenoma 8 | 559
group 4 medulloblastoma 8 | 1,855
juvenile dermatomyositis 8 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
Atherosclerosis 7 | 291
Atopic dermatitis 7 | 952
Brain Ischemia 7 | 110
Breast Neoplasms 7 | 445
Cardiomegaly 7 | 116
Congestive heart failure 7 | 113
Duchenne muscular dystrophy 7 | 601
Dull intelligence 7 | 645
Fever 7 | 138
Hepatomegaly 7 | 285
Hyperglycemia 7 | 137
Intellectual disability 7 | 1,016
Low intelligence 7 | 645
Lung Neoplasms 7 | 232
Mammary Neoplasms 7 | 425
Mental Depression 7 | 333
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Parkinson's disease 7 | 392
Pick disease 7 | 1,894
Poor school performance 7 | 645
Renal Cell Carcinoma 7 | 214
astrocytoma 7 | 1,146
pituitary cancer 7 | 1,972
Essential Hypertension 6 | 94
Malaria 6 | 160
Melanoma 6 | 711
Polycystic ovary syndrome 6 | 360
Status Epilepticus 6 | 98
active ulcerative colitis 6 | 764
aldosterone-producing adenoma 6 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
cutaneous lupus erythematosus 6 | 1,057
dermatomyositis 6 | 966

Tissue

Digestive Tract 64 | 17,369
Blood and immune system 63 | 16,909
Endocrine System 63 | 18,159
Female tissues 63 | 17,400
Liver and Pancreas 63 | 16,750
Male tissues 63 | 17,142
Nervous System 63 | 16,725
Respiratory system 63 | 16,393
Skin and soft tissues 63 | 17,230
Urinary Tract 63 | 16,678
Cardiovascular System 62 | 15,192

Target Family

Non-IDG 23 | 12,091
Enzyme 14 | 4,145
Kinase 8 | 634
Transporter 7 | 473
GPCR 6 | 408
Ion Channel 5 | 344
Epigenetic 1 | 242

GO Component

caveola 64 | 64
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
E-selectin SELE Tchem Non-IDG -3.44926 2672.1 919
Rho GTPase-activating protein 7 DLC1 Tbio Enzyme -1.93185 106.7 137
Pituitary adenylate cyclase-activating polypeptide type I receptor ADCYAP1R1 Tchem GPCR -1.98111 94.8 184
Protein patched homolog 1 PTCH1 Tbio Non-IDG -3.04637 1057.4 452
Plasmalemma vesicle-associated protein PLVAP Tbio Non-IDG -2.30946 195.9 167
Protein kinase C and casein kinase substrate in neurons protein 2 PACSIN2 Tbio Enzyme -1.38534 27.2 135
Blood vessel epicardial substance BVES Tbio Non-IDG -1.50394 37.0 168
EH domain-containing protein 2 EHD2 Tbio Non-IDG -1.49972 32.2 144
TGF-beta receptor type-2 TGFBR2 Tchem Kinase -2.84120 665.1 548
Mitogen-activated protein kinase 3 MAPK3 Tchem Kinase -3.66226 3484.0 1440