Development Level

Tbio 80 | 11,445
Tdark 14 | 6,588
Tchem 3 | 1,598

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 15 | 979
embryonic lethality prior to o... 6 | 239
embryonic lethality prior to t... 3 | 278
hypoactivity 3 | 132
increased mean corpuscular vol... 3 | 92
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
decreased leukocyte cell numbe... 2 | 73
decreased lymphocyte cell numb... 2 | 83
decreased mean corpuscular hem... 2 | 31
decreased neutrophil cell numb... 2 | 42
decreased total body fat amoun... 2 | 207
impaired glucose tolerance 2 | 75
increased circulating HDL chol... 2 | 80
increased circulating choleste... 2 | 66
increased lean body mass 2 | 172
increased lymphocyte cell numb... 2 | 32
increased mean platelet volume 2 | 45
male infertility 2 | 123
prenatal lethality prior to he... 2 | 87
abnormal behavioral response t... 1 | 66
abnormal chorioallantoic fusio... 1 | 8
abnormal lung morphology 1 | 26
abnormal pancreas morphology 1 | 13
absent pinna reflex 1 | 23
cardiovascular system phenotyp... 1 | 36
decreased circulating HDL chol... 1 | 68
decreased circulating glucose ... 1 | 126
decreased circulating potassiu... 1 | 20
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased hemoglobin content 1 | 68
decreased startle reflex 1 | 75
enlarged heart 1 | 210
hyperactivity 1 | 148
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating free fat... 1 | 20
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97
thrombocytosis 1 | 27

Disease

Carcinoma 66 | 11,493
ovarian cancer 65 | 8,520
osteosarcoma 39 | 7,950
medulloblastoma, large-cell 37 | 6,241
group 3 medulloblastoma 35 | 4,104
psoriasis 34 | 6,694
glioblastoma 28 | 5,792
lung cancer 27 | 4,740
Multiple myeloma 26 | 1,332
acute quadriplegic myopathy 22 | 1,158
atypical teratoid / rhabdoid tumor 21 | 5,112
malignant mesothelioma 20 | 3,232
Kidney cancer 19 | 2,613
diabetes mellitus 18 | 1,728
ependymoma 18 | 4,679
Waldenstrons macroglobulinemia 17 | 765
oligodendroglioma 17 | 2,850
astrocytoma 16 | 1,146
Breast cancer 15 | 3,578
Intellectual disability 14 | 1,016
dermatomyositis 14 | 966
primitive neuroectodermal tumor 14 | 3,035
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
Pick disease 10 | 1,894
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
Amyotrophic lateral sclerosis 9 | 451
Cancer 9 | 2,499
Dull intelligence 9 | 645
Low intelligence 9 | 645
Mental Retardation 9 | 645
Mental deficiency 9 | 645
Poor school performance 9 | 645
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
acute myeloid leukemia 8 | 783
astrocytic glioma 8 | 2,597
lung adenocarcinoma 8 | 2,716
progressive supranuclear palsy 8 | 676
subependymal giant cell astrocytoma 8 | 2,287
adult high grade glioma 7 | 3,801
juvenile dermatomyositis 7 | 1,187
pancreatic cancer 7 | 2,398
HIV Infections 6 | 102
Microcephaly 6 | 166
atypical teratoid/rhabdoid tumor 6 | 357
invasive ductal carcinoma 6 | 2,951
non-small cell lung cancer 6 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
tuberculosis and treatment for 6 months 6 | 409
Anteverted nostril 5 | 191
Conductive hearing loss 5 | 123
Epilepsy 5 | 792
Gaucher disease type 1 5 | 180
Retinitis Pigmentosa 5 | 226
hepatocellular carcinoma 5 | 547
pediatric high grade glioma 5 | 1,064
Abnormality of the retinal vasculature 4 | 59
Autosomal recessive predisposition 4 | 1,442
Cleft Palate 4 | 271
Feeding difficulties 4 | 127
Frontotemporal dementia 4 | 51
Obesity 4 | 678
Rheumatoid arthritis 4 | 1,191
Sensorineural Hearing Loss (disorder) 4 | 284
Short stature 4 | 531
Uranostaphyloschisis 4 | 167
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
gastric cancer 4 | 459
group 4 medulloblastoma 4 | 1,855
medulloblastoma 4 | 720
nasopharyngeal carcinoma 4 | 1,058
non primary Sjogren syndrome sicca 4 | 891
sonic hedgehog group medulloblastoma 4 | 467
Atopic dermatitis 3 | 952
Bilateral fifth finger clinodactyly 3 | 110
Blind Vision 3 | 111
Blindness, Legal 3 | 110
Broad flat nasal bridge 3 | 236
Byzanthine arch palate 3 | 194
Cognitive delay 3 | 608
Curvature of little finger 3 | 110
Down syndrome 3 | 499
Glaucoma 3 | 239
Liver cancer 3 | 604
Mental and motor retardation 3 | 608
Nasal bridge wide 3 | 236
Neurogenic Muscular Atrophy 3 | 139
Neurogenic muscle atrophy, especially in the lower limbs 3 | 139
Ophthalmoplegia 3 | 106
Polycystic ovary syndrome 3 | 360
Schizophrenia 3 | 1,160
Skeletal muscle atrophy 3 | 139
Ventricular Septal Defects 3 | 119
breast carcinoma 3 | 1,638
cystic fibrosis 3 | 1,696
glioblastoma multiforme 3 | 142
hereditary spastic paraplegia 3 | 318
muscle degeneration 3 | 139
pituitary cancer 3 | 1,972
primary pancreatic ductal adenocarcinoma 3 | 1,109
spina bifida 3 | 1,074

Tissue

Digestive Tract 96 | 17,369
Endocrine System 96 | 18,159
Female tissues 96 | 17,400
Liver and Pancreas 96 | 16,750
Male tissues 96 | 17,142
Nervous System 96 | 16,725
Respiratory system 96 | 16,393
Urinary Tract 96 | 16,678
Blood and immune system 95 | 16,909
Skin and soft tissues 95 | 17,230
Cardiovascular System 94 | 15,192

Target Family

Non-IDG 77 | 12,091
Enzyme 17 | 4,145
Epigenetic 1 | 242
Kinase 1 | 634
Transcription Factor 1 | 1,400

GO Component

catalytic step 2 spliceosome 97 | 97
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
NACHT domain- and WD repeat-containing protein 1 NWD1 Tdark Non-IDG 0.08 1.22 3
Probable ATP-dependent RNA helicase DDX5 DDX5 Tbio Enzyme -2.08566 121.1 344
RNA-binding protein 8A RBM8A Tbio Non-IDG -3.16448 1415.1 94
RNA-binding protein Raly RALY Tbio Non-IDG -1.12263 14.4 176
Telomerase protein component 1 TEP1 Tbio Enzyme -1.74492 50.6 71
Pre-mRNA-splicing factor RBM22 RBM22 Tbio Non-IDG -0.84549 7.65 130
Heterogeneous nuclear ribonucleoprotein M HNRNPM Tbio Non-IDG -1.64443 45.9 331
G patch domain-containing protein 1 GPATCH1 Tdark Non-IDG 0.54 0.26 14
Serine/threonine-protein kinase PRP4 homolog PRPF4B Tchem Kinase -1.17233 14.7 144
Pre-mRNA-splicing factor CWC22 homolog CWC22 Tbio Non-IDG -3.08456 1172.8 103