Development Level

Tbio 7 | 11,445

IMPC Phenotype

abnormal heart morphology 1 | 162
abnormal response to new envir... 1 | 10
decreased circulating amylase ... 1 | 28
decreased mean corpuscular vol... 1 | 79
increased circulating chloride... 1 | 41
increased heart weight 1 | 62
preweaning lethality, complete... 1 | 979

Disease

Cardiomyopathy 6 | 116
Dilated cardiomyopathy 6 | 56
Hypertrophic Cardiomyopathy 6 | 117
Cardiomyopathy, Dilated 5 | 83
Familial isolated dilated cardiomyopathy 5 | 41
LEFT VENTRICULAR NONCOMPACTION 10 5 | 40
LEFT VENTRICULAR NONCOMPACTION 8 5 | 40
Carcinoma 4 | 11,493
Cardiomyopathy, Hypertrophic, Familial 4 | 9
Left ventricular noncompaction 4 | 26
Autosomal recessive predisposition 3 | 1,442
Cardiomyopathies 3 | 110
Cardiomyopathy, Hypertrophic 3 | 24
Congestive heart failure 3 | 113
Myopathy 3 | 185
lung cancer 3 | 4,740
psoriasis 3 | 6,694
Acute coronary syndrome 2 | 39
Amyloidosis 2 | 67
Cardiomegaly 2 | 116
Cerebrovascular disease 2 | 238
Coronary artery disease 2 | 268
Death, Sudden, Cardiac 2 | 5
Distal limb muscle weakness due to peripheral neuropathy 2 | 62
Distal muscle weakness 2 | 62
EMG: myopathic abnormalities 2 | 22
Foot dorsiflexor weakness 2 | 27
Foot-drop 2 | 27
Gas gangrene 2 | 17
Heart Diseases 2 | 43
Heart disease 2 | 306
Heart failure 2 | 162
Kidney Failure 2 | 111
Late-onset proximal muscle weakness 2 | 2
Muscle biopsy shows dystrophic changes 2 | 39
Muscular dystrophy 2 | 75
Neck muscle weakness 2 | 17
Other restrictive cardiomyopathy 2 | 4
Primary cutaneous amyloidosis 2 | 29
Pulmonary embolism 2 | 55
Respiratory insufficiency due to muscle weakness 2 | 37
Restrictive cardiomyopathy 2 | 11
Sudden Cardiac Death 2 | 29
Tachycardia, Ventricular 2 | 22
acute quadriplegic myopathy 2 | 1,158
adult high grade glioma 2 | 3,801
atypical teratoid / rhabdoid tumor 2 | 5,112
colon cancer 2 | 1,478
diabetes mellitus 2 | 1,728
glioblastoma 2 | 5,792
group 4 medulloblastoma 2 | 1,855
lung adenocarcinoma 2 | 2,716
medulloblastoma, large-cell 2 | 6,241
ovarian cancer 2 | 8,520
Alexander disease 1 | 11
Avian influenza 1 | 7
CARDIOMYOPATHY, DILATED, 1I 1 | 1
CATARACT 16, MULTIPLE TYPES 1 | 15
Carcinoma, Renal Cell 1 | 124
Carcinoma, Squamous Cell 1 | 110
Cardiomyopathy, Familial Hypertrophic, 1 1 | 6
Cardiomyopathy, Familial Hypertrophic, 4 1 | 1
Chronic Obstructive Airway Disease 1 | 37
Congenital Fiber Type Disproportion 1 | 7
Congenital myopathy with fiber type disproportion 1 | 9
Dilated cardiomyopathy 1D 1 | 3
Flexion contracture - elbow 1 | 32
Glomerulonephritis 1 | 46
Heart Injuries 1 | 3
Hernias, Diaphragmatic, Congenital 1 | 17
Hyporeflexia of lower limbs 1 | 10
MUSCULAR DYSTROPHY, LIMB-GIRDLE, TYPE 2R 1 | 1
MYOPATHY, MYOFIBRILLAR, DESMIN-RELATED 1 | 1
Mitral regurgitation, mild 1 | 32
Mitral valve insufficiency 1 | 49
Muscle Rigidity 1 | 49
Muscular Dystrophy, Limb-Girdle, Type 1E 1 | 2
Myofibrillar Myopathy 1 | 9
Myofibrillar myopathy 1 1 | 6
Myotonic dystrophy type 1 1 | 17
Neurodegenerative Diseases 1 | 38
Nuclear cataract 1 | 19
Nuclear non-senile cataract 1 | 18
Pericarditis 1 | 13
Peroneal muscle atrophy 1 | 2
Posterior polar cataract 1 | 6
Pulmonary Disease, Chronic Obstructive 1 | 31
Rapidly progressive 1 | 27
Rapidly progressive disorder 1 | 27
Reduced systolic function 1 | 5
Renal Cell Carcinoma 1 | 214
Restrictive heart failure 1 | 1
Scapular weakness 1 | 23
Scapuloperoneal Syndrome, Neurogenic, Kaeser Type 1 | 1
Scapuloperoneal weakness 1 | 3
Shoulder girdle muscle atrophy 1 | 6
Ventricular Dysfunction, Left 1 | 22
Ventricular hypertrophy 1 | 6
Weak cry 1 | 17
Winged scapula 1 | 23

Tissue

Blood and immune system 7 | 16,909
Cardiovascular System 7 | 15,192
Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Male tissues 7 | 17,142
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678
Nervous System 6 | 16,725
Respiratory system 6 | 16,393

Target Family

Non-IDG 7 | 12,091

GO Component

cardiac myofibril 7 | 7
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Desmin DES Tbio Non-IDG -1.56068 36.6 991
Myosin-binding protein C, cardiac-type MYBPC3 Tbio Non-IDG -2.45618 287.6 139
Alpha-crystallin B chain CRYAB Tbio Non-IDG -2.29243 192.0 1100
Myosin-7B MYH7B Tbio Non-IDG -1.18655 12.1 17
Myosin regulatory light chain 2, ventricular/cardiac muscle isoform MYL2 Tbio Non-IDG -2.23022 155.8 222
Troponin T, cardiac muscle TNNT2 Tbio Non-IDG -3.19980 1554.3 829
Troponin I, cardiac muscle TNNI3 Tbio Non-IDG -3.55281 3485.6 1706