Development Level

Tbio 2 | 11,178
Tchem 2 | 1,885

IMPC Phenotype

abnormal embryo size 1 | 220
decreased circulating magnesiu... 1 | 13
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
preweaning lethality, incomple... 1 | 499
small epididymis 1 | 3

Disease

Astrocytoma, Pilocytic 4 | 3,006
adult high grade glioma 4 | 3,701
astrocytic glioma 4 | 2,530
atypical teratoid / rhabdoid tumor 4 | 4,971
ependymoma 4 | 4,559
glioblastoma 4 | 5,635
medulloblastoma, large-cell 4 | 6,086
oligodendroglioma 4 | 2,768
primitive neuroectodermal tumor 4 | 2,957
subependymal giant cell astrocytoma 4 | 2,230
Carcinoma 3 | 11,192
Pick disease 3 | 1,856
ovarian cancer 3 | 8,297
Breast cancer 2 | 3,469
Cancer 2 | 2,388
Hepatolenticular Degeneration 2 | 23
Hypertrophy, Left Ventricular 2 | 23
Left Ventricular Hypertrophy 2 | 46
Prostatic Neoplasms 2 | 472
Rheumatoid arthritis 2 | 1,156
Waldenstrons macroglobulinemia 2 | 742
colon cancer 2 | 1,428
group 4 medulloblastoma 2 | 1,806
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,902
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,204
lung cancer 2 | 4,607
malignant mesothelioma 2 | 3,135
psoriasis 2 | 6,514
spina bifida 2 | 1,053
3p- syndrome 1 | 21
Adenocarcinoma of lung 1 | 140
Adenocarcinoma of lung (disorder) 1 | 59
Aniridia 1 | 25
Aniridia cerebellar ataxia mental deficiency 1 | 2
Ascaridiasis 1 | 3
Ataxic cerebral palsy 1 | 7
Atopic dermatitis 1 | 915
Autosomal dominant cerebellar ataxia 1 | 31
Autosomal recessive predisposition 1 | 1,407
Bipolar Disorder 1 | 646
Brain Injuries 1 | 63
Breast abscess 1 | 5
Chemical and Drug Induced Liver Injury 1 | 188
Chronic obstructive pulmonary disease 1 | 175
Congenital myasthenic syndrome 14 1 | 3
Cornea plana 1 | 12
Corneal disease 1 | 30
Endocarditis 1 | 19
Endometrial cancer 1 | 301
Essential Hypertension 1 | 92
Exocrine pancreatic insufficiency 1 | 30
Explosive speech 1 | 9
Gaucher disease type 3 1 | 65
Gillespie syndrome 1 | 2
Intractable Eczema 1 | 5
Keratoconjunctivitis sicca 1 | 25
Keratoconus 1 | 111
Kidney cancer 1 | 2,548
Liver cancer 1 | 589
Liver transplant rejection 1 | 5
Lobular neoplasia 1 | 14
Mask-like facies 1 | 25
Mastitis 1 | 48
Movement Disorders 1 | 54
Multiple myeloma 1 | 1,296
Myocardial Ischemia 1 | 162
Neurodegenerative disease 1 | 402
Neurodevelopmental Disorders 1 | 70
Osteomyelitis 1 | 42
Pancreatitis 1 | 118
Pneumothorax 1 | 22
Prevention of Cardiac Transplant Rejection 1 | 15
Prevention of Kidney Transplant Rejection 1 | 17
Prevention of Liver Transplant Rejection 1 | 15
Prevention of Transplant Rejection 1 | 6
Renal transplant rejection 1 | 13
Scanning speech 1 | 9
Schizophrenia 1 | 1,136
Septic arthritis 1 | 8
Severe Recalcitrant Psoriasis 1 | 12
Tear film insufficiency 1 | 15
Transplanted organ rejection 1 | 10
Viral esophagitis 1 | 2
aldosterone-producing adenoma 1 | 646
cystic fibrosis 1 | 1,629
ductal carcinoma in situ 1 | 1,686
group 3 medulloblastoma 1 | 4,002
hereditary spastic paraplegia 1 | 313
interstitial lung disease 1 | 287
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,872
invasive ductal carcinoma 1 | 2,867
lung adenocarcinoma 1 | 2,627
lung carcinoma 1 | 2,755
medulloblastoma 1 | 702
non-small cell lung cancer 1 | 2,799
osteosarcoma 1 | 7,766
pancreatic cancer 1 | 2,322
primary pancreatic ductal adenocarcinoma 1 | 1,071
severe Alzheimer's disease 1 | 46
ulcerative colitis 1 | 1,765

Tissue

Blood and immune system 4 | 16,909
Cardiovascular System 4 | 15,192
Digestive Tract 4 | 17,369
Endocrine System 4 | 18,159
Female tissues 4 | 17,400
Liver and Pancreas 4 | 16,750
Male tissues 4 | 17,142
Nervous System 4 | 16,725
Respiratory system 4 | 16,393
Skin and soft tissues 4 | 17,230
Urinary Tract 4 | 16,678

Target Family

Enzyme 2 | 4,145
Ion Channel 1 | 344
Non-IDG 1 | 12,091

GO Component

calcineurin complex 4 | 4
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

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