Development Level

Tbio 40 | 11,445
Tchem 9 | 1,598
Tdark 3 | 6,588
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 6 | 979
preweaning lethality, incomple... 4 | 499
increased circulating sodium l... 3 | 71
absent pinna reflex 2 | 23
decreased body weight 2 | 161
decreased circulating insulin ... 2 | 76
decreased grip strength 2 | 116
decreased total body fat amoun... 2 | 207
increased circulating chloride... 2 | 41
increased mean corpuscular hem... 2 | 96
abnormal behavior 1 | 298
abnormal coat- hair morphology 1 | 19
abnormal coping response 1 | 1
abnormal digestive system phys... 1 | 1
abnormal embryo size 1 | 220
abnormal femur morphology 1 | 14
abnormal kidney morphology 1 | 65
abnormal vibrissa morphology 1 | 25
abnormal vitreous body morphol... 1 | 10
absent teeth 1 | 3
cardiovascular system phenotyp... 1 | 36
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating potassiu... 1 | 20
decreased circulating triglyce... 1 | 79
decreased lean body mass 1 | 135
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating choleste... 1 | 66
increased circulating total pr... 1 | 28
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
increased vertical activity 1 | 24
limb grasping 1 | 41
persistence of hyaloid vascula... 1 | 33
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
stereotypic behavior 1 | 3
trunk curl 1 | 16

Disease

Carcinoma 44 | 11,493
ovarian cancer 24 | 8,520
psoriasis 20 | 6,694
osteosarcoma 19 | 7,950
Kidney cancer 18 | 2,613
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,955
pancreatic cancer 17 | 2,398
glioblastoma 16 | 5,792
lung cancer 16 | 4,740
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
ependymoma 12 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
lung carcinoma 12 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
ulcerative colitis 11 | 1,819
Autosomal recessive predisposition 10 | 1,442
Breast cancer 10 | 3,578
malignant mesothelioma 10 | 3,232
medulloblastoma, large-cell 10 | 6,241
atypical teratoid / rhabdoid tumor 9 | 5,112
lung adenocarcinoma 9 | 2,716
Astrocytoma, Pilocytic 8 | 3,081
Cancer 8 | 2,499
Liver Cirrhosis, Experimental 8 | 769
astrocytic glioma 8 | 2,597
interstitial cystitis 8 | 2,312
invasive ductal carcinoma 8 | 2,951
non-small cell lung cancer 8 | 2,890
diabetes mellitus 7 | 1,728
group 3 medulloblastoma 7 | 4,104
oligodendroglioma 7 | 2,850
subependymal giant cell astrocytoma 7 | 2,287
Diarrhea 6 | 253
Kidney disease 6 | 430
Nonsyndromic deafness 6 | 142
acute quadriplegic myopathy 6 | 1,158
adult high grade glioma 6 | 3,801
cystic fibrosis 6 | 1,696
juvenile dermatomyositis 6 | 1,187
pituitary cancer 6 | 1,972
Amyotrophic lateral sclerosis 5 | 451
Down syndrome 5 | 499
Duchenne muscular dystrophy 5 | 601
Liver cancer 5 | 604
Rheumatoid arthritis 5 | 1,191
Sensorineural hearing loss 5 | 106
astrocytoma 5 | 1,146
breast carcinoma 5 | 1,638
ductal carcinoma in situ 5 | 1,745
esophageal adenocarcinoma 5 | 737
gastric carcinoma 5 | 807
primary pancreatic ductal adenocarcinoma 5 | 1,109
Alzheimer's disease 4 | 658
Breast Neoplasms 4 | 445
Failure to gain weight 4 | 365
Hypertension 4 | 396
Hypophosphatemia 4 | 40
Intellectual disability 4 | 1,016
Melanoma 4 | 711
Obesity 4 | 678
Pediatric failure to thrive 4 | 365
Prostatic Neoplasms 4 | 495
Schizophrenia 4 | 1,160
Short stature 4 | 531
Skin cancer 4 | 469
Vascular disease 4 | 319
Waldenstrons macroglobulinemia 4 | 765
aldosterone-producing adenoma 4 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
colon cancer 4 | 1,478
dermatomyositis 4 | 966
hereditary spastic paraplegia 4 | 318
mucosa-associated lymphoid tissue lymphoma 4 | 484
nephrosclerosis 4 | 333
pediatric high grade glioma 4 | 1,064
tuberculosis 4 | 2,010
urothelial carcinoma 4 | 318
Anemia 3 | 365
Animal Mammary Neoplasms 3 | 136
Autistic Disorder 3 | 364
Cognitive delay 3 | 608
Dull intelligence 3 | 645
Focal glomerulosclerosis 3 | 37
Glomerulosclerosis, Focal Segmental 3 | 28
Lens Opacities 3 | 231
Mammary Neoplasms 3 | 425
Mental and motor retardation 3 | 608
Multiple myeloma 3 | 1,332
Nephrolithiasis 3 | 56
Osteoarthritis 3 | 184
Polyhydramnios 3 | 108
Poor school performance 3 | 645
Proteinuria 3 | 144
Type 2 diabetes mellitus 3 | 272
acute myeloid leukemia 3 | 783
cutaneous lupus erythematosus 3 | 1,057
facioscapulohumeral dystrophy 3 | 288
nasopharyngeal carcinoma 3 | 1,058
pancreatic carcinoma 3 | 562
posterior fossa group A ependymoma 3 | 468

Tissue

Digestive Tract 52 | 17,369
Skin and soft tissues 52 | 17,230
Liver and Pancreas 51 | 16,750
Female tissues 50 | 17,400
Male tissues 50 | 17,142
Urinary Tract 50 | 16,678
Endocrine System 49 | 18,159
Nervous System 49 | 16,725
Blood and immune system 48 | 16,909
Respiratory system 46 | 16,393
Cardiovascular System 39 | 15,192

Target Family

Non-IDG 35 | 12,091
Enzyme 9 | 4,145
Transporter 7 | 473
Ion Channel 2 | 344

GO Component

brush border 53 | 53
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Harmonin USH1C Tbio Non-IDG -2.10689 124.7 188
Aquaporin-1 AQP1 Tbio Non-IDG -3.08125 1107.4 374
Na(+)/H(+) exchange regulatory cofactor NHE-RF4 PDZD3 Tbio Non-IDG -0.76581 6.17 121
LIM domain and actin-binding protein 1 LIMA1 Tbio Non-IDG -1.26880 23.6 187
Ankyrin repeat and SAM domain-containing protein 4B ANKS4B Tbio Non-IDG -0.12494 1.58 59
Sucrase-isomaltase, intestinal SI Tchem Enzyme -1.84903 67.8 62
Adseverin SCIN Tbio Non-IDG -1.90989 89.8 72
Sodium-coupled neutral amino acid transporter 2 SLC38A2 Tbio Transporter -1.98482 96.5 91
Alpha-actinin-4 ACTN4 Tbio Non-IDG -2.22522 178.2 300
Ral guanine nucleotide dissociation stimulator RALGDS Tbio Non-IDG -2.85677 683.6 102