Development Level

Tbio 101 | 11,651
Tdark 10 | 6,593
Tchem 7 | 1,388
Tclin 1 | 612

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 8 | 979
abnormal retina morphology 5 | 71
preweaning lethality, incomple... 5 | 499
abnormal behavior 3 | 298
decreased total body fat amoun... 3 | 207
hyperactivity 3 | 148
male infertility 3 | 123
abnormal embryo size 2 | 220
abnormal heart left ventricle ... 2 | 16
abnormal retinal vasculature m... 2 | 27
abnormal sleep behavior 2 | 70
decreased body length 2 | 101
decreased grip strength 2 | 116
decreased startle reflex 2 | 75
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
hydrometra 2 | 53
improved glucose tolerance 2 | 79
increased heart weight 2 | 62
increased or absent threshold ... 2 | 101
increased total body fat amoun... 2 | 134
small superior vagus ganglion 2 | 74
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal coat appearance 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal ear morphology 1 | 9
abnormal forebrain morphology 1 | 10
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal neural tube closure 1 | 46
abnormal optic disc morphology 1 | 10
abnormal retinal blood vessel ... 1 | 26
abnormal startle reflex 1 | 15
abnormal tail morphology 1 | 25
abnormal testis morphology 1 | 43
absent startle reflex 1 | 24
cyanosis 1 | 7
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating free fat... 1 | 31
decreased circulating insulin ... 1 | 76
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased fasted circulating g... 1 | 65
decreased lean body mass 1 | 135
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased threshold for audito... 1 | 26
decreased vertical activity 1 | 208
edema 1 | 59
enlarged uterus 1 | 11
female infertility 1 | 60
hemorrhage 1 | 23
hypoactivity 1 | 132
impaired pupillary reflex 1 | 26
increased body length 1 | 32
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased cardiac muscle contr... 1 | 8
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating insulin ... 1 | 3
increased circulating iron lev... 1 | 30
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased lean body mass 1 | 172
increased startle reflex 1 | 112
increased vertical activity 1 | 24
mammalian phenotype 1 | 17
microphthalmia 1 | 26
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
shortened PR interval 1 | 6
shortened RR interval 1 | 17
small testis 1 | 58
tremors 1 | 39

Disease

Carcinoma 83 | 11,493
ovarian cancer 78 | 8,520
psoriasis 56 | 6,694
osteosarcoma 55 | 7,950
medulloblastoma, large-cell 54 | 6,241
intraductal papillary-mucinous carcinoma (IPMC) 49 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 47 | 3,291
atypical teratoid / rhabdoid tumor 46 | 5,112
ependymoma 45 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 44 | 2,955
glioblastoma 43 | 5,792
non-small cell lung cancer 43 | 2,890
invasive ductal carcinoma 42 | 2,951
Breast cancer 37 | 3,578
lung adenocarcinoma 37 | 2,716
lung cancer 37 | 4,740
interstitial cystitis 36 | 2,312
ductal carcinoma in situ 35 | 1,745
group 3 medulloblastoma 35 | 4,104
pancreatic cancer 29 | 2,398
Cancer 28 | 2,499
adult high grade glioma 27 | 3,801
oligodendroglioma 26 | 2,850
subependymal giant cell astrocytoma 26 | 2,287
malignant mesothelioma 25 | 3,232
Astrocytoma, Pilocytic 24 | 3,081
lung carcinoma 24 | 2,843
primitive neuroectodermal tumor 24 | 3,035
spina bifida 24 | 1,074
Kidney cancer 23 | 2,613
pituitary cancer 22 | 1,972
astrocytic glioma 21 | 2,597
breast carcinoma 20 | 1,638
cystic fibrosis 18 | 1,696
Schizophrenia 16 | 1,160
pancreatic ductal adenocarcinoma liver metastasis 16 | 1,962
ulcerative colitis 15 | 1,819
active Crohn's disease 14 | 922
group 4 medulloblastoma 14 | 1,855
nasopharyngeal carcinoma 14 | 1,058
Pick disease 13 | 1,894
primary pancreatic ductal adenocarcinoma 13 | 1,109
Prostatic Neoplasms 12 | 495
active ulcerative colitis 12 | 764
colon cancer 12 | 1,478
esophageal adenocarcinoma 12 | 737
adrenocortical carcinoma 11 | 1,428
gastric carcinoma 11 | 807
Atopic dermatitis 10 | 952
astrocytoma 10 | 1,146
tuberculosis 10 | 2,010
Autosomal recessive predisposition 9 | 1,442
Intellectual disability 9 | 1,016
cutaneous lupus erythematosus 9 | 1,057
diabetes mellitus 9 | 1,728
Bipolar Disorder 8 | 666
Melanoma 8 | 711
pediatric high grade glioma 8 | 1,064
progressive supranuclear palsy 8 | 676
Breast Neoplasms 7 | 445
Down syndrome 7 | 499
Mammary Neoplasms 7 | 425
Skin cancer 7 | 469
acute myeloid leukemia 7 | 783
acute quadriplegic myopathy 7 | 1,158
dermatomyositis 7 | 966
fibroadenoma 7 | 559
medulloblastoma 7 | 720
non primary Sjogren syndrome sicca 7 | 891
Dull intelligence 6 | 645
Inflammatory bowel disease 6 | 151
Kidney disease 6 | 430
Liver Cirrhosis, Experimental 6 | 769
Liver cancer 6 | 604
Low intelligence 6 | 645
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Multiple myeloma 6 | 1,332
Muscle hypotonia 6 | 571
Poor school performance 6 | 645
Stomach Neoplasms 6 | 300
aldosterone-producing adenoma 6 | 665
interstitial lung disease 6 | 298
juvenile dermatomyositis 6 | 1,187
primary Sjogren syndrome 6 | 735
urothelial carcinoma 6 | 318
Animal Mammary Neoplasms 5 | 136
Colorectal Neoplasms 5 | 243
Diarrhea 5 | 253
Duchenne muscular dystrophy 5 | 601
Endometriosis 5 | 540
Lymphoid leukemia 5 | 160
Mammary Neoplasms, Animal 5 | 136
Rheumatoid arthritis 5 | 1,191
Splenomegaly 5 | 190
chronic rhinosinusitis 5 | 512
mucosa-associated lymphoid tissue lymphoma 5 | 484
nephrosclerosis 5 | 333
periodontitis 5 | 293
Mental Depression 4 | 333

Tissue

Digestive Tract 115 | 17,369
Endocrine System 115 | 18,159
Female tissues 115 | 17,400
Urinary Tract 114 | 16,678
Skin and soft tissues 113 | 17,230
Male tissues 112 | 17,142
Nervous System 110 | 16,725
Respiratory system 110 | 16,393
Blood and immune system 109 | 16,909
Liver and Pancreas 109 | 16,750
Cardiovascular System 104 | 15,192

Target Family

Non-IDG 99 | 12,091
Enzyme 10 | 4,145
Kinase 6 | 634
GPCR 2 | 408
Epigenetic 1 | 242
Transcription Factor 1 | 1,400

GO Component

bicellular tight junction 119 | 119
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Claudin-12 CLDN12 Tbio Non-IDG -1.03235 8.71 137
Claudin-8 CLDN8 Tbio Non-IDG -1.50382 29.7 184
Claudin-6 CLDN6 Tbio Non-IDG -1.76879 66.0 370
Claudin-15 CLDN15 Tbio Non-IDG -1.33932 19.3 154
Protein crumbs homolog 3 CRB3 Tbio Non-IDG -1.22596 16.1 79
Pituitary adenylate cyclase-activating polypeptide type I receptor ADCYAP1R1 Tchem GPCR -1.98111 94.8 184
Cingulin-like protein 1 CGNL1 Tbio Non-IDG -0.84049 8.54 64
Protein kinase C iota type PRKCI Tchem Kinase -1.71694 51.2 148
Blood vessel epicardial substance BVES Tbio Non-IDG -1.50394 37.0 168
Junctional adhesion molecule-like JAML Tbio Non-IDG -1.66747 47.0 202