Development Level

Tbio 118 | 11,445
Tchem 36 | 1,598
Tclin 24 | 613
Tdark 6 | 6,588

Collection

RFA-RM-18-021 2 | 328
Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 13 | 979
abnormal behavior 9 | 298
decreased bone mineral content 7 | 151
decreased grip strength 7 | 116
abnormal bone structure 6 | 187
decreased total body fat amoun... 6 | 207
increased circulating HDL chol... 6 | 80
abnormal embryo size 5 | 220
decreased prepulse inhibition 5 | 82
embryonic lethality prior to t... 5 | 278
increased mean corpuscular vol... 5 | 92
abnormal gait 4 | 69
abnormal pericardium morpholog... 4 | 26
decreased bone mineral density 4 | 126
decreased startle reflex 4 | 75
embryonic growth retardation 4 | 106
enlarged heart 4 | 210
hypoactivity 4 | 132
increased blood urea nitrogen ... 4 | 48
increased circulating alkaline... 4 | 122
increased circulating choleste... 4 | 66
increased circulating creatini... 4 | 38
increased mean corpuscular hem... 4 | 96
thrombocytopenia 4 | 56
tremors 4 | 39
abnormal eye morphology 3 | 68
abnormal limb bud morphology 3 | 17
abnormal sleep behavior 3 | 70
decreased body length 3 | 101
decreased body weight 3 | 161
decreased fasted circulating g... 3 | 65
decreased lean body mass 3 | 135
decreased vertical activity 3 | 208
hyperactivity 3 | 148
increased circulating chloride... 3 | 41
increased circulating total pr... 3 | 28
increased lean body mass 3 | 172
increased or absent threshold ... 3 | 101
increased startle reflex 3 | 112
pale yolk sac 3 | 25
pallor 3 | 34
prenatal lethality prior to he... 3 | 87
preweaning lethality, incomple... 3 | 499
abnormal bone mineralization 2 | 38
abnormal heart morphology 2 | 162
abnormal neural tube closure 2 | 46
abnormal placenta size 2 | 20
abnormal retina morphology 2 | 71
abnormal seminal vesicle morph... 2 | 114
abnormal startle reflex 2 | 15
abnormal tail movements 2 | 12
absent vibrissae 2 | 12
cardiovascular system phenotyp... 2 | 36
decreased circulating HDL chol... 2 | 68
decreased circulating choleste... 2 | 93
decreased circulating insulin ... 2 | 76
decreased circulating triglyce... 2 | 79
decreased exploration in new e... 2 | 11
decreased leukocyte cell numbe... 2 | 73
embryonic lethality prior to o... 2 | 239
impaired glucose tolerance 2 | 75
improved glucose tolerance 2 | 79
increased bone mineral content 2 | 108
increased circulating calcium ... 2 | 34
increased circulating iron lev... 2 | 30
increased circulating phosphat... 2 | 26
increased circulating potassiu... 2 | 29
increased circulating serum al... 2 | 22
increased circulating sodium l... 2 | 71
increased mean platelet volume 2 | 45
increased total body fat amoun... 2 | 134
limb grasping 2 | 41
mammalian phenotype 2 | 17
abnormal craniofacial morpholo... 1 | 33
abnormal ear morphology 1 | 9
abnormal embryo turning 1 | 31
abnormal epididymis morphology 1 | 42
abnormal head morphology 1 | 10
abnormal lung morphology 1 | 26
abnormal neural tube morpholog... 1 | 12
abnormal vibrissa morphology 1 | 25
decreased circulating calcium ... 1 | 36
decreased circulating chloride... 1 | 30
decreased heart rate variabili... 1 | 13
decreased mean corpuscular hem... 1 | 31
enlarged uterus 1 | 11
impaired righting response 1 | 26
increased anti-nuclear antigen... 1 | 19
increased bone mineral density 1 | 72
increased circulating aspartat... 1 | 15
increased circulating bilirubi... 1 | 16
increased circulating fructosa... 1 | 13
increased circulating triglyce... 1 | 42
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased monocyte cell number 1 | 63
long tibia 1 | 25
small superior vagus ganglion 1 | 74
small testis 1 | 58
trunk curl 1 | 16

Disease

Carcinoma 141 | 11,493
ovarian cancer 94 | 8,520
psoriasis 87 | 6,694
osteosarcoma 86 | 7,950
medulloblastoma, large-cell 74 | 6,241
glioblastoma 73 | 5,792
lung cancer 73 | 4,740
ependymoma 72 | 4,679
atypical teratoid / rhabdoid tumor 68 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 60 | 3,291
Cancer 58 | 2,499
lung carcinoma 55 | 2,843
Breast cancer 53 | 3,578
malignant mesothelioma 53 | 3,232
adult high grade glioma 52 | 3,801
non-small cell lung cancer 52 | 2,890
intraductal papillary-mucinous adenoma (IPMA) 51 | 2,955
lung adenocarcinoma 51 | 2,716
intraductal papillary-mucinous carcinoma (IPMC) 50 | 2,989
group 3 medulloblastoma 48 | 4,104
Astrocytoma, Pilocytic 47 | 3,081
invasive ductal carcinoma 47 | 2,951
Kidney cancer 45 | 2,613
interstitial cystitis 45 | 2,312
pancreatic cancer 45 | 2,398
oligodendroglioma 42 | 2,850
Autosomal recessive predisposition 40 | 1,442
astrocytic glioma 40 | 2,597
subependymal giant cell astrocytoma 40 | 2,287
pituitary cancer 39 | 1,972
primitive neuroectodermal tumor 37 | 3,035
ductal carcinoma in situ 35 | 1,745
cystic fibrosis 33 | 1,696
tuberculosis 30 | 2,010
colon cancer 27 | 1,478
ulcerative colitis 27 | 1,819
pancreatic ductal adenocarcinoma liver metastasis 24 | 1,962
gastric carcinoma 23 | 807
Rheumatoid arthritis 22 | 1,191
group 4 medulloblastoma 22 | 1,855
Epilepsy 21 | 792
Intellectual disability 21 | 1,016
Schizophrenia 21 | 1,160
spina bifida 21 | 1,074
Pick disease 20 | 1,894
primary pancreatic ductal adenocarcinoma 20 | 1,109
Dull intelligence 19 | 645
Low intelligence 19 | 645
Mental Retardation 19 | 645
Mental deficiency 19 | 645
Poor school performance 19 | 645
breast carcinoma 19 | 1,638
active ulcerative colitis 18 | 764
Osteoporosis 17 | 363
diabetes mellitus 17 | 1,728
Down syndrome 16 | 499
Hypertension 16 | 396
Prostatic Neoplasms 16 | 495
acute quadriplegic myopathy 16 | 1,158
fibroadenoma 16 | 559
Kidney disease 15 | 430
Liver Cirrhosis, Experimental 15 | 769
adrenocortical carcinoma 15 | 1,428
cutaneous lupus erythematosus 15 | 1,057
nasopharyngeal carcinoma 15 | 1,058
Bipolar Disorder 14 | 666
Hypertensive disease 14 | 292
Melanoma 14 | 711
active Crohn's disease 14 | 922
nephrosclerosis 14 | 333
pediatric high grade glioma 14 | 1,064
Breast Neoplasms 13 | 445
Muscle hypotonia 13 | 571
Seizures 13 | 596
Skin cancer 13 | 469
esophageal adenocarcinoma 13 | 737
pancreatic carcinoma 13 | 562
Cognitive delay 12 | 608
Duchenne muscular dystrophy 12 | 601
Global developmental delay 12 | 608
Liver cancer 12 | 604
Mammary Neoplasms 12 | 425
Mental and motor retardation 12 | 608
Metabolic acidosis 12 | 90
Short stature 12 | 531
Vascular disease 12 | 319
astrocytoma 12 | 1,146
atypical teratoid/rhabdoid tumor 12 | 357
dermatomyositis 12 | 966
primary Sjogren syndrome 12 | 735
Alzheimer's disease 11 | 658
Anemia 11 | 365
Atopic dermatitis 11 | 952
Disease Models, Animal 11 | 155
Hepatomegaly 11 | 285
Liver disease 11 | 237
aldosterone-producing adenoma 11 | 665
Asthma 10 | 385
Small head 10 | 374
gastric cancer 10 | 459

Tissue

Digestive Tract 181 | 17,369
Endocrine System 179 | 18,159
Female tissues 178 | 17,400
Male tissues 176 | 17,142
Urinary Tract 176 | 16,678
Nervous System 175 | 16,725
Liver and Pancreas 174 | 16,750
Skin and soft tissues 172 | 17,230
Blood and immune system 167 | 16,909
Respiratory system 163 | 16,393
Cardiovascular System 153 | 15,192

Target Family

Non-IDG 96 | 12,091
Transporter 46 | 473
Enzyme 13 | 4,145
GPCR 10 | 408
Ion Channel 10 | 344
Kinase 9 | 634

GO Component

basolateral plasma membrane 184 | 184
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium/bile acid cotransporter SLC10A1 Tchem Transporter -2.69150 476.1 163
Adherens junction-associated protein 1 AJAP1 Tbio Non-IDG -1.20907 21.2 25
Potassium voltage-gated channel subfamily C member 2 KCNC2 Tclin Ion Channel -1.45272 28.7 178
Suppressor of tumorigenicity 14 protein ST14 Tchem Non-IDG -2.50215 338.3 309
Sodium bicarbonate cotransporter 3 SLC4A7 Tbio Transporter -1.82039 64.7 133
Beta-1,4-galactosyltransferase 1 B4GALT1 Tbio Enzyme -2.34454 211.1 130
Electrogenic sodium bicarbonate cotransporter 1 SLC4A4 Tbio Transporter -2.63743 436.2 124
Annexin A13 ANXA13 Tbio Non-IDG -1.19458 15.6 162
Moesin MSN Tbio Non-IDG -2.61389 361.7 550
Folate receptor alpha FOLR1 Tchem Non-IDG -2.33242 206.1 303