Development Level

Tbio 103 | 10,625
Tchem 45 | 1,890
Tclin 23 | 602
Tdark 3 | 7,003

IMPC Term

decreased bone mineral content 9 | 157
decreased bone mineral density 8 | 126
decreased lean body mass 8 | 195
preweaning lethality, complete... 8 | 633
abnormal behavior 7 | 226
decreased total body fat amoun... 7 | 186
decreased grip strength 6 | 123
increased circulating alkaline... 6 | 119
abnormal bone structure 5 | 131
hypoactivity 5 | 89
decreased body weight 4 | 174
increased blood urea nitrogen ... 4 | 44
increased grip strength 4 | 83
increased mean corpuscular hem... 4 | 93
increased mean corpuscular vol... 4 | 91
short tibia 4 | 82
thrombocytopenia 4 | 46
tremors 4 | 34
abnormal bone mineralization 3 | 55
abnormal gait 3 | 51
decreased fasted circulating g... 3 | 49
decreased prepulse inhibition 3 | 52
decreased startle reflex 3 | 48
embryonic lethality prior to t... 3 | 187
increased circulating creatini... 3 | 29
increased circulating phosphat... 3 | 24
increased circulating potassiu... 3 | 31
increased circulating total pr... 3 | 20
abnormal retinal pigmentation 2 | 61
abnormal seminal vesicle morph... 2 | 47
abnormal sleep behavior 2 | 63
abnormal startle reflex 2 | 14
decreased body length 2 | 108
decreased caudal vertebrae num... 2 | 49
decreased circulating HDL chol... 2 | 77
decreased circulating choleste... 2 | 85
decreased circulating insulin ... 2 | 75
decreased circulating triglyce... 2 | 83
decreased effector memory CD8-... 2 | 24
decreased leukocyte cell numbe... 2 | 54
enlarged heart 2 | 111
hyperactivity 2 | 108
impaired glucose tolerance 2 | 52
improved glucose tolerance 2 | 56
increased bone mineral content 2 | 92
increased bone mineral density 2 | 52
increased caudal vertebrae num... 2 | 8
increased circulating HDL chol... 2 | 63
increased circulating chloride... 2 | 43
increased circulating serum al... 2 | 25
increased or absent threshold ... 2 | 128
prenatal lethality prior to he... 2 | 64
abnormal QRS complex 1 | 25
abnormal ear morphology 1 | 5
abnormal embryo size 1 | 112
abnormal epididymis morphology 1 | 31
abnormal eye morphology 1 | 38
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 51
abnormal kidney morphology 1 | 30
abnormal lens morphology 1 | 73
abnormal lung morphology 1 | 15
abnormal neural tube closure 1 | 37
abnormal respiratory quotient 1 | 9
abnormal retina morphology 1 | 100
abnormal rib morphology 1 | 28
abnormal skin morphology 1 | 23
abnormal snout morphology 1 | 18
abnormal tail movements 1 | 12
abnormal thoracic vertebrae mo... 1 | 16
absent vibrissae 1 | 14
craniofacial phenotype 1 | 9
decreased circulating calcium ... 1 | 33
decreased circulating chloride... 1 | 32
decreased exploration in new e... 1 | 9
decreased heart weight 1 | 44
decreased hemoglobin content 1 | 53
decreased mean corpuscular vol... 1 | 50
decreased neutrophil cell numb... 1 | 37
enlarged heart atrium 1 | 2
increased circulating alanine ... 1 | 11
increased circulating aspartat... 1 | 17
increased circulating calcium ... 1 | 32
increased circulating choleste... 1 | 53
increased circulating fructosa... 1 | 11
increased circulating glucose ... 1 | 16
increased circulating iron lev... 1 | 25
increased circulating triglyce... 1 | 24
increased eosinophil cell numb... 1 | 9
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased rib number 1 | 41
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
lethargy 1 | 5
limb grasping 1 | 35
long tibia 1 | 13
shortened PQ interval 1 | 6
straub tail 1 | 26
vertebral fusion 1 | 23

Disease

ovarian cancer 87 | 8,484
psoriasis 84 | 6,685
osteosarcoma 80 | 7,933
medulloblastoma, large-cell 75 | 6,234
lung cancer 68 | 4,466
glioblastoma 62 | 5,572
intraductal papillary-mucinous neoplasm (IPMN) 56 | 3,289
Cancer 50 | 2,346
lung carcinoma 50 | 2,844
non-small cell lung cancer 50 | 2,798
atypical teratoid / rhabdoid tumor 48 | 4,369
intraductal papillary-mucinous adenoma (IPMA) 47 | 2,956
lung adenocarcinoma 47 | 2,713
intraductal papillary-mucinous carcinoma (IPMC) 46 | 2,988
malignant mesothelioma 46 | 3,162
Breast cancer 43 | 3,094
invasive ductal carcinoma 43 | 2,950
pilocytic astrocytoma 43 | 3,086
pancreatic cancer 40 | 2,300
interstitial cystitis 39 | 2,299
oligodendroglioma 39 | 2,849
pediatric high grade glioma 39 | 2,712
pituitary cancer 39 | 1,972
Carcinoma 38 | 2,147
subependymal giant cell astrocytoma 38 | 2,287
ependymoma 37 | 2,514
primitive neuroectodermal tumor 35 | 3,031
astrocytic glioma 32 | 2,241
ductal carcinoma in situ 31 | 1,745
ulcerative colitis 31 | 2,087
cystic fibrosis 30 | 1,665
atypical teratoid/rhabdoid tumor 29 | 1,095
group 4 medulloblastoma 26 | 1,875
adult high grade glioma 25 | 2,148
tuberculosis 25 | 1,557
colon cancer 24 | 1,475
gastric carcinoma 23 | 832
pancreatic ductal adenocarcinoma liver metastasis 22 | 1,795
posterior fossa group B ependymoma 22 | 1,530
Pick disease 19 | 1,893
Rheumatoid Arthritis 19 | 1,160
posterior fossa group A ependymoma 19 | 1,511
primary pancreatic ductal adenocarcinoma 19 | 1,271
sonic hedgehog group medulloblastoma 19 | 1,482
breast carcinoma 18 | 1,614
group 3 medulloblastoma 18 | 2,254
medulloblastoma 18 | 1,524
spina bifida 18 | 1,064
Down syndrome 17 | 548
Prostatic Neoplasms 16 | 471
acute quadriplegic myopathy 16 | 1,157
diabetes mellitus 16 | 1,663
adrenocortical carcinoma 15 | 1,427
astrocytoma 15 | 1,493
cutaneous lupus erythematosus 15 | 1,056
fibroadenoma 15 | 557
nasopharyngeal carcinoma 14 | 1,056
nephrosclerosis 14 | 329
pancreatic carcinoma 14 | 567
Kidney disease 13 | 396
Osteoporosis 13 | 257
esophageal adenocarcinoma 13 | 737
Duchenne muscular dystrophy 12 | 602
Intellectual disability 12 | 573
Mammary Neoplasms 12 | 410
Vascular disease 12 | 281
Epilepsy 11 | 346
Hypertensive disease 11 | 193
active Crohn's disease 11 | 918
active ulcerative colitis 11 | 477
dermatomyositis 11 | 933
primary Sjogren syndrome 11 | 789
Alzheimer's disease 10 | 644
Endometriosis 10 | 535
Hypertension 10 | 287
Metabolic acidosis 10 | 49
Obesity 10 | 616
Schizophrenia 10 | 501
juvenile dermatomyositis 10 | 1,189
Animal Mammary Neoplasms 9 | 136
Asthma 9 | 349
Atopic dermatitis 9 | 944
Colonic Neoplasms 9 | 126
aldosterone-producing adenoma 9 | 664
autosomal dominant Emery-Dreifuss muscular dystrophy 9 | 499
progressive supranuclear palsy 9 | 674
Amyotrophic Lateral Sclerosis 8 | 431
Autistic Disorder 8 | 320
Colorectal Neoplasms 8 | 217
Mammary Neoplasms, Experimental 8 | 150
Multiple myeloma 8 | 1,327
Neurodegenerative disease 8 | 383
Peripheral Neuropathy 8 | 303
Stomach Neoplasms 8 | 282
mucosa-associated lymphoid tissue lymphoma 8 | 480
ovarian neoplasm 8 | 97
Waldenstrons macroglobulinemia 7 | 765
acute myeloid leukemia 7 | 780
chronic rhinosinusitis 7 | 512
gastric cancer 7 | 430

Tissue

Digestive Tract 173 | 18,473
Female tissues 173 | 18,647
Nervous System 173 | 18,561
Urinary Tract 173 | 18,444
Endocrine System 172 | 18,512
Liver and Pancreas 171 | 18,136
Blood and immune system 170 | 17,995
Male tissues 170 | 17,969
Skin and soft tissues 170 | 18,115
Cardiovascular System 169 | 17,958
Respiratory system 168 | 17,484

Target Family

Non-IDG 90 | 11,971
Transporter 44 | 473
Enzyme 13 | 4,146
Ion Channel 10 | 341
Kinase 9 | 634
GPCR 8 | 406

GO Component

basolateral plasma membrane 174 | 174
nucleus 5,107 | 5,107
cytoplasm 4,985 | 4,985
plasma membrane 4,118 | 4,118
integral component of membrane 3,679 | 3,679
cytosol 3,265 | 3,265
extracellular exosome 2,758 | 2,758
nucleoplasm 2,717 | 2,717
membrane 1,906 | 1,906
extracellular region 1,493 | 1,493
integral component of plasma m... 1,406 | 1,406
extracellular space 1,304 | 1,304
mitochondrion 1,231 | 1,231
Golgi apparatus 864 | 864
endoplasmic reticulum 859 | 859
endoplasmic reticulum membrane 848 | 848
nucleolus 815 | 815
Golgi membrane 659 | 659
perinuclear region of cytoplas... 611 | 611
cell surface 594 | 594
intracellular 548 | 548
intracellular membrane-bounded... 537 | 537
cell junction 451 | 451
mitochondrial inner membrane 425 | 425
centrosome 409 | 409
focal adhesion 383 | 383
protein complex 355 | 355
cytoskeleton 343 | 343
dendrite 329 | 329
mitochondrial matrix 322 | 322
cell-cell adherens junction 307 | 307
neuronal cell body 303 | 303
microtubule 294 | 294
lysosomal membrane 278 | 278
apical plasma membrane 277 | 277
proteinaceous extracellular ma... 244 | 244
neuron projection 229 | 229
nuclear membrane 218 | 218
early endosome 217 | 217
axon 214 | 214
lysosome 210 | 210
endosome 208 | 208
actin cytoskeleton 205 | 205
external side of plasma membra... 205 | 205
postsynaptic membrane 204 | 204
extracellular matrix 198 | 198
nuclear speck 197 | 197
membrane raft 196 | 196
endoplasmic reticulum lumen 192 | 192
transcription factor complex 184 | 184
endosome membrane 182 | 182
early endosome membrane 180 | 180
nuclear chromatin 169 | 169
synapse 166 | 166
cell-cell junction 161 | 161
nuclear envelope 156 | 156
lamellipodium 153 | 153
mitochondrial outer membrane 148 | 148
blood microparticle 147 | 147
myelin sheath 144 | 144
postsynaptic density 144 | 144
cytoplasmic vesicle 143 | 143
microtubule organizing center 137 | 137
cytoplasmic, membrane-bounded ... 132 | 132
ER to Golgi transport vesicle ... 131 | 131
microtubule cytoskeleton 127 | 127
receptor complex 127 | 127
phagocytic vesicle membrane 126 | 126
cytoplasmic vesicle membrane 125 | 125
midbody 125 | 125
trans-Golgi network 124 | 124
cell cortex 119 | 119
cilium 118 | 118
late endosome 116 | 116
spindle 116 | 116
intracellular ribonucleoprotei... 114 | 114
vesicle 112 | 112
Z disc 110 | 110
bicellular tight junction 110 | 110
anchored component of membrane 109 | 109
growth cone 109 | 109
integral component of lumenal ... 108 | 108
late endosome membrane 107 | 107
endomembrane system 106 | 106
centriole 105 | 105
recycling endosome 104 | 104
spindle pole 104 | 104
perikaryon 103 | 103
integral component of endoplas... 101 | 101
intermediate filament 101 | 101
melanosome 101 | 101
chromosome 100 | 100
dendritic spine 99 | 99
ubiquitin ligase complex 99 | 99
peroxisome 98 | 98
nuclear matrix 97 | 97
PML body 94 | 94
Golgi lumen 93 | 93
keratin filament 93 | 93
trans-Golgi network membrane 92 | 92

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Desmoplakin DSP Tbio Non-IDG -2.90088 786.5 167
Sodium/hydrogen exchanger 4 SLC9A4 Tdark Transporter -1.25841 17.4 6
Sodium/calcium exchanger 2 SLC8A2 Tbio Transporter -1.56223 31.9 51
Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 Tclin Ion Channel -2.92762 876.7 339
Beta-arrestin-1 ARRB1 Tchem Non-IDG -2.54226 366.3 416
Zinc transporter ZIP5 SLC39A5 Tbio Transporter -1.03936 12.4 60
Transferrin receptor protein 1 TFRC Tbio Non-IDG -3.39868 2437.0 1167
Band 3 anion transport protein SLC4A1 Tbio Transporter -3.02453 1271.7 133
Solute carrier family 22 member 6 SLC22A6 Tclin Transporter -2.27998 196.4 186
Lactoperoxidase LPO Tbio Enzyme -2.69742 442.5 160