Development Level

Tbio 59 | 10,625
Tchem 9 | 1,890
Tdark 8 | 7,003

IMPC Term

preweaning lethality, complete... 5 | 633
abnormal coat/hair pigmentatio... 4 | 54
decreased body weight 3 | 174
decreased lean body mass 3 | 195
increased fasted circulating g... 3 | 68
abnormal behavior 2 | 226
abnormal humerus morphology 2 | 11
abnormal lens morphology 2 | 73
abnormal retina morphology 2 | 100
abnormal retinal blood vessel ... 2 | 18
abnormal retinal vasculature m... 2 | 15
abnormal spleen morphology 2 | 36
cataract 2 | 26
decreased bone mineral content 2 | 157
enlarged heart 2 | 111
increased startle reflex 2 | 38
irregularly shaped pupil 2 | 7
abnormal QRS complex 1 | 25
abnormal body wall morphology 1 | 7
abnormal cranium morphology 1 | 32
abnormal digit morphology 1 | 13
abnormal embryo size 1 | 112
abnormal eye morphology 1 | 38
abnormal femur morphology 1 | 14
abnormal gait 1 | 51
abnormal incisor color 1 | 2
abnormal iris morphology 1 | 12
abnormal maxilla morphology 1 | 16
abnormal motor learning 1 | 4
abnormal optic disc morphology 1 | 10
abnormal pelvic girdle bone mo... 1 | 11
abnormal sleep behavior 1 | 63
abnormal snout morphology 1 | 18
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
cleft palate 1 | 6
convulsive seizures 1 | 11
corneal opacity 1 | 25
decreased body length 1 | 108
decreased bone mineral density 1 | 126
decreased cervical vertebrae n... 1 | 12
decreased erythrocyte cell num... 1 | 43
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased hemoglobin content 1 | 53
decreased leukocyte cell numbe... 1 | 54
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular hem... 1 | 19
decreased rib number 1 | 59
decreased threshold for audito... 1 | 32
decreased total body fat amoun... 1 | 186
embryonic lethality prior to t... 1 | 187
enlarged adrenal glands 1 | 3
enlarged kidney 1 | 7
enlarged uterus 1 | 3
female infertility 1 | 34
hydrometra 1 | 13
immune system phenotype 1 | 17
impaired glucose tolerance 1 | 52
impaired pupillary reflex 1 | 14
improved glucose tolerance 1 | 56
increased NK T cell number 1 | 11
increased body length 1 | 20
increased exploration in new e... 1 | 56
increased hematocrit 1 | 36
increased mean corpuscular vol... 1 | 91
increased total body fat amoun... 1 | 57
increased vertical activity 1 | 18
male infertility 1 | 62
microcephaly 1 | 3
mydriasis 1 | 9
narrow eye opening 1 | 15
oligodactyly 1 | 14
persistence of hyaloid vascula... 1 | 22
polycystic kidney 1 | 9
polydactyly 1 | 22
preweaning lethality, incomple... 1 | 260
syndactyly 1 | 4
thrombocytopenia 1 | 46

Disease

ovarian cancer 51 | 8,484
glioblastoma 41 | 5,572
pilocytic astrocytoma 40 | 3,086
psoriasis 40 | 6,685
atypical teratoid / rhabdoid tumor 35 | 4,369
pancreatic cancer 35 | 2,300
Breast cancer 34 | 3,094
medulloblastoma, large-cell 34 | 6,234
osteosarcoma 34 | 7,933
lung carcinoma 33 | 2,844
pediatric high grade glioma 32 | 2,712
lung cancer 31 | 4,466
malignant mesothelioma 31 | 3,162
Carcinoma 30 | 2,147
intraductal papillary-mucinous adenoma (IPMA) 30 | 2,956
invasive ductal carcinoma 30 | 2,950
intraductal papillary-mucinous carcinoma (IPMC) 29 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 28 | 3,289
primary pancreatic ductal adenocarcinoma 27 | 1,271
lung adenocarcinoma 26 | 2,713
Duchenne muscular dystrophy 24 | 602
gastric carcinoma 24 | 832
interstitial cystitis 24 | 2,299
posterior fossa group A ependymoma 24 | 1,511
non-small cell lung cancer 23 | 2,798
sonic hedgehog group medulloblastoma 23 | 1,482
cystic fibrosis 22 | 1,665
primitive neuroectodermal tumor 22 | 3,031
juvenile dermatomyositis 21 | 1,189
pituitary cancer 21 | 1,972
ulcerative colitis 21 | 2,087
breast carcinoma 20 | 1,614
oligodendroglioma 20 | 2,849
autosomal dominant Emery-Dreifuss muscular dystrophy 19 | 499
subependymal giant cell astrocytoma 19 | 2,287
Cancer 18 | 2,346
ductal carcinoma in situ 18 | 1,745
adrenocortical carcinoma 16 | 1,427
Becker muscular dystrophy 14 | 187
ependymoma 14 | 2,514
nasopharyngeal carcinoma 14 | 1,056
astrocytic glioma 12 | 2,241
diabetes mellitus 12 | 1,663
esophageal adenocarcinoma 12 | 737
group 3 medulloblastoma 12 | 2,254
group 4 medulloblastoma 12 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,795
adult high grade glioma 11 | 2,148
astrocytoma 11 | 1,493
cutaneous lupus erythematosus 11 | 1,056
limb girdle muscular dystrophy 2A 11 | 156
Endometriosis 10 | 535
colon cancer 10 | 1,475
glioblastoma multiforme 10 | 347
posterior fossa group B ependymoma 10 | 1,530
acute quadriplegic myopathy 9 | 1,157
Atopic dermatitis 8 | 944
atypical teratoid/rhabdoid tumor 8 | 1,095
dermatomyositis 8 | 933
Epidermolysis bullosa 7 | 21
active ulcerative colitis 7 | 477
interstitial lung disease 7 | 291
urothelial carcinoma 7 | 318
Heart disease 6 | 279
Intellectual disability 6 | 573
Kidney disease 6 | 396
Prostatic Neoplasms 6 | 471
Rheumatoid Arthritis 6 | 1,160
Vascular disease 6 | 281
acute myeloid leukemia 6 | 780
non primary Sjogren syndrome sicca 6 | 840
Amyotrophic Lateral Sclerosis 5 | 431
Arthritis 5 | 248
Down syndrome 5 | 548
Glaucoma 5 | 134
Keratoconus 5 | 47
Myopia 5 | 99
Neoplasm Invasiveness 5 | 127
Pick disease 5 | 1,893
active Crohn's disease 5 | 918
fibroadenoma 5 | 557
non-small cell lung carcinoma 5 | 413
tuberculosis 5 | 1,557
Age related macular degeneration 4 | 84
Alport syndrome 4 | 21
Animal Mammary Neoplasms 4 | 136
Barrett's esophagus 4 | 183
Bullous pemphigoid 4 | 17
Cataract 4 | 104
IGA Glomerulonephritis 4 | 454
Kidney cancer 4 | 118
Multiple myeloma 4 | 1,327
Spontaneous abortion 4 | 108
Syndactyly 4 | 56
cystic fibrosis and chronic rhinosinusitis 4 | 213
fascioscapulohumeral muscular dystrophy 4 | 100
head and neck cancer 4 | 270
nephrosclerosis 4 | 329
primary Sjogren syndrome 4 | 789
pterygium 4 | 74

Tissue

Cardiovascular System 75 | 17,958
Digestive Tract 75 | 18,473
Endocrine System 75 | 18,512
Female tissues 75 | 18,647
Liver and Pancreas 75 | 18,136
Nervous System 75 | 18,561
Skin and soft tissues 75 | 18,115
Urinary Tract 75 | 18,444
Blood and immune system 74 | 17,995
Male tissues 74 | 17,969
Respiratory system 74 | 17,484

Target Family

Non-IDG 66 | 11,971
Enzyme 8 | 4,146
Kinase 1 | 634
Transcription Factor 1 | 1,400

GO Component

basement membrane 76 | 76
nucleus 5,107 | 5,107
cytoplasm 4,985 | 4,985
plasma membrane 4,118 | 4,118
integral component of membrane 3,679 | 3,679
cytosol 3,265 | 3,265
extracellular exosome 2,758 | 2,758
nucleoplasm 2,717 | 2,717
membrane 1,906 | 1,906
extracellular region 1,493 | 1,493
integral component of plasma m... 1,406 | 1,406
extracellular space 1,304 | 1,304
mitochondrion 1,231 | 1,231
Golgi apparatus 864 | 864
endoplasmic reticulum 859 | 859
endoplasmic reticulum membrane 848 | 848
nucleolus 815 | 815
Golgi membrane 659 | 659
perinuclear region of cytoplas... 611 | 611
cell surface 594 | 594
intracellular 548 | 548
intracellular membrane-bounded... 537 | 537
cell junction 451 | 451
mitochondrial inner membrane 425 | 425
centrosome 409 | 409
focal adhesion 383 | 383
protein complex 355 | 355
cytoskeleton 343 | 343
dendrite 329 | 329
mitochondrial matrix 322 | 322
cell-cell adherens junction 307 | 307
neuronal cell body 303 | 303
microtubule 294 | 294
lysosomal membrane 278 | 278
apical plasma membrane 277 | 277
proteinaceous extracellular ma... 244 | 244
neuron projection 229 | 229
nuclear membrane 218 | 218
early endosome 217 | 217
axon 214 | 214
lysosome 210 | 210
endosome 208 | 208
actin cytoskeleton 205 | 205
external side of plasma membra... 205 | 205
postsynaptic membrane 204 | 204
extracellular matrix 198 | 198
nuclear speck 197 | 197
membrane raft 196 | 196
endoplasmic reticulum lumen 192 | 192
transcription factor complex 184 | 184
endosome membrane 182 | 182
early endosome membrane 180 | 180
basolateral plasma membrane 174 | 174
nuclear chromatin 169 | 169
synapse 166 | 166
cell-cell junction 161 | 161
nuclear envelope 156 | 156
lamellipodium 153 | 153
mitochondrial outer membrane 148 | 148
blood microparticle 147 | 147
myelin sheath 144 | 144
postsynaptic density 144 | 144
cytoplasmic vesicle 143 | 143
microtubule organizing center 137 | 137
cytoplasmic, membrane-bounded ... 132 | 132
ER to Golgi transport vesicle ... 131 | 131
microtubule cytoskeleton 127 | 127
receptor complex 127 | 127
phagocytic vesicle membrane 126 | 126
cytoplasmic vesicle membrane 125 | 125
midbody 125 | 125
trans-Golgi network 124 | 124
cell cortex 119 | 119
cilium 118 | 118
late endosome 116 | 116
spindle 116 | 116
intracellular ribonucleoprotei... 114 | 114
vesicle 112 | 112
Z disc 110 | 110
bicellular tight junction 110 | 110
anchored component of membrane 109 | 109
growth cone 109 | 109
integral component of lumenal ... 108 | 108
late endosome membrane 107 | 107
endomembrane system 106 | 106
centriole 105 | 105
recycling endosome 104 | 104
spindle pole 104 | 104
perikaryon 103 | 103
integral component of endoplas... 101 | 101
intermediate filament 101 | 101
melanosome 101 | 101
chromosome 100 | 100
dendritic spine 99 | 99
ubiquitin ligase complex 99 | 99
peroxisome 98 | 98
nuclear matrix 97 | 97
PML body 94 | 94
Golgi lumen 93 | 93
keratin filament 93 | 93
trans-Golgi network membrane 92 | 92

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Laminin subunit alpha-2 LAMA2 Tbio Non-IDG -2.48634 321.9 131
Laminin subunit beta-4 LAMB4 Tdark Non-IDG -0.65741 5.19 10
Lysyl oxidase homolog 1 LOXL1 Tbio Enzyme -2.51621 344.5 145
Laminin subunit gamma-1 LAMC1 Tchem Non-IDG -1.73437 53.6 239
Integrin alpha-6 ITGA6 Tchem Non-IDG -2.25486 168.8 756
CD151 antigen CD151 Tbio Non-IDG -2.35980 249.3 307
Structural maintenance of chromosomes protein 3 SMC3 Tbio Non-IDG -2.05162 104.9 234
von Willebrand factor A domain-containing protein 2 VWA2 Tbio Non-IDG -0.98975 11.0 66
Prolyl 3-hydroxylase 2 P3H2 Tbio Enzyme -2.47612 287.3 48
Hemicentin-1 HMCN1 Tbio Non-IDG -1.33845 22.8 11