Development Level

Tbio 65 | 11,651
Tdark 16 | 6,593
Tchem 3 | 1,388
Tclin 1 | 612

IMPC Phenotype

preweaning lethality, complete... 7 | 979
preweaning lethality, incomple... 6 | 499
impaired glucose tolerance 3 | 75
abnormal behavior 2 | 298
decreased fasted circulating g... 2 | 65
decreased grip strength 2 | 116
decreased lean body mass 2 | 135
increased mean corpuscular hem... 2 | 96
increased total body fat amoun... 2 | 134
abnormal coat appearance 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal forebrain morphology 1 | 10
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
abnormal hindbrain morphology 1 | 10
abnormal limb morphology 1 | 13
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
anophthalmia 1 | 33
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating potassiu... 1 | 20
decreased heart rate variabili... 1 | 13
decreased heart weight 1 | 27
decreased prepulse inhibition 1 | 82
decreased respiratory quotient 1 | 16
decreased spleen weight 1 | 10
edema 1 | 59
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating chloride... 1 | 41
increased circulating glucose ... 1 | 24
increased circulating serum al... 1 | 22
increased fasted circulating g... 1 | 76
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular vol... 1 | 92
increased prepulse inhibition 1 | 32
male infertility 1 | 123
microphthalmia 1 | 26
polydactyly 1 | 7
short tibia 1 | 97
thrombocytopenia 1 | 56

Disease

Carcinoma 65 | 11,493
ependymoma 49 | 4,679
osteosarcoma 38 | 7,950
ovarian cancer 36 | 8,520
psoriasis 28 | 6,694
Kidney cancer 27 | 2,613
chronic rhinosinusitis 27 | 512
atypical teratoid / rhabdoid tumor 25 | 5,112
glioblastoma 24 | 5,792
nasopharyngeal carcinoma 24 | 1,058
Primary ciliary dyskinesia 23 | 76
medulloblastoma, large-cell 23 | 6,241
Breast cancer 18 | 3,578
Ciliary Motility Disorders 18 | 38
lung adenocarcinoma 17 | 2,716
Kartagener Syndrome 16 | 38
adult high grade glioma 16 | 3,801
Polydactyly 15 | 107
Situs Inversus 15 | 65
primitive neuroectodermal tumor 14 | 3,035
Liver cancer 13 | 604
lung carcinoma 13 | 2,843
Autosomal recessive predisposition 12 | 1,442
Ciliopathy 12 | 71
astrocytic glioma 12 | 2,597
group 3 medulloblastoma 12 | 4,104
lung cancer 12 | 4,740
malignant mesothelioma 12 | 3,232
Astrocytoma, Pilocytic 11 | 3,081
Pick disease 11 | 1,894
Retinitis Pigmentosa 11 | 226
Cancer 10 | 2,499
Ciliary Dyskinesia, Primary, 1 10 | 27
Intellectual disability 10 | 1,016
Nephronophthisis 10 | 80
Nystagmus 9 | 317
Obesity 9 | 678
Short stature 9 | 531
group 4 medulloblastoma 9 | 1,855
non-small cell lung cancer 9 | 2,890
Asphyxiating thoracic dystrophy 8 | 44
Bardet-Biedl syndrome 8 | 51
Congenital hypoplasia of penis 8 | 176
Male infertility 8 | 206
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
invasive ductal carcinoma 8 | 2,951
oligodendroglioma 8 | 2,850
pancreatic cancer 8 | 2,398
Dull intelligence 7 | 645
Low intelligence 7 | 645
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Poor school performance 7 | 645
Schizophrenia 7 | 1,160
Ulnar polydactyly of fingers 7 | 47
cystic fibrosis and chronic rhinosinusitis 7 | 214
Cryptorchidism 6 | 296
Electroretinogram abnormal 6 | 95
Fundus dystrophy 6 | 83
Hydrocephalus 6 | 152
Hypogonadism 6 | 173
Melanoma 6 | 711
Multiple myeloma 6 | 1,332
Short Rib-Polydactyly Syndrome 6 | 13
Sinusitis 6 | 65
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
pituitary cancer 6 | 1,972
tuberculosis 6 | 2,010
Anteverted nostril 5 | 191
Atopic dermatitis 5 | 952
Bardet-Biedl syndrome 1 5 | 22
Brachydactyly 5 | 156
Broad flat nasal bridge 5 | 236
Bronchiectasis 5 | 64
Cataract 5 | 297
Cone dystrophy 5 | 71
Fibrosis, Liver 5 | 32
Gastrointestinal Stromal Tumors 5 | 48
Hepatomegaly 5 | 285
Hypertensive disease 5 | 292
Increase in blood pressure 5 | 119
Jeune thoracic dystrophy 5 | 10
Joubert syndrome 5 | 66
Lens Opacities 5 | 231
Multicystic Dysplastic Kidney 5 | 52
Nasal bridge wide 5 | 236
Optic Atrophy 5 | 242
Recurrent respiratory infections 5 | 141
Sensenbrenner syndrome 5 | 17
Skin cancer 5 | 469
medulloblastoma 5 | 720
pediatric high grade glioma 5 | 1,064
primary pancreatic ductal adenocarcinoma 5 | 1,109
Cognitive delay 4 | 608
Congenital hypoplasia of ovary 4 | 30
Global developmental delay 4 | 608
Hypoplastic ovary 4 | 30
Mental and motor retardation 4 | 608
Small head 4 | 374
Uranostaphyloschisis 4 | 167

Tissue

Endocrine System 84 | 18,159
Female tissues 80 | 17,400
Respiratory system 80 | 16,393
Skin and soft tissues 80 | 17,230
Digestive Tract 79 | 17,369
Male tissues 79 | 17,142
Nervous System 79 | 16,725
Urinary Tract 77 | 16,678
Blood and immune system 76 | 16,909
Liver and Pancreas 74 | 16,750
Cardiovascular System 67 | 15,192

Target Family

Non-IDG 71 | 12,091
Enzyme 7 | 4,145
Transcription Factor 4 | 1,400
Kinase 3 | 634

GO Component

axoneme 85 | 85
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cilia- and flagella-associated protein 74 CFAP74 Tdark Non-IDG 0.38 0.16 21
Oxygen-regulated protein 1 RP1 Tbio Non-IDG 0.30 0.88 40
Sperm flagellar protein 1 SPEF1 Tdark Non-IDG -0.39794 2.39 16
Tubulin monoglycylase TTLL3 TTLL3 Tbio Enzyme -0.53902 4.01 18
Bardet-Biedl syndrome 7 protein BBS7 Tbio Non-IDG -1.05503 10.4 159
Beclin 1-associated autophagy-related key regulator ATG14 Tbio Non-IDG -1.63390 38.6 127
Phosphatidylinositol 3-kinase catalytic subunit type 3 PIK3C3 Tchem Kinase -2.33238 204.8 739
Intraflagellar transport protein 57 homolog IFT57 Tbio Non-IDG -1.31031 23.8 197
A-kinase anchor protein 14 AKAP14 Tbio Enzyme 0.30 0.50 69
Radial spoke head protein 4 homolog A RSPH4A Tdark Non-IDG -0.78817 5.47 40