Development Level

Tbio 13 | 10,625
Tchem 5 | 1,890

IMPC Term

abnormal bone structure 1 | 131
abnormal heart left ventricle ... 1 | 20
abnormal locomotor activation 1 | 26
abnormal optic disc morphology 1 | 10
abnormal retina morphology 1 | 100
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 77
decreased circulating alanine ... 1 | 53
decreased circulating alkaline... 1 | 41
decreased circulating choleste... 1 | 85
decreased circulating serum al... 1 | 79
decreased circulating total pr... 1 | 41
decreased fasted circulating g... 1 | 49
decreased grip strength 1 | 123
decreased kidney weight 1 | 7
decreased lean body mass 1 | 195
decreased pulmonary respirator... 1 | 4
decreased spleen weight 1 | 13
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
enlarged stomach 1 | 2
impaired glucose tolerance 1 | 52
increased body weight 1 | 42
increased circulating alanine ... 1 | 11
increased circulating alkaline... 1 | 119
increased circulating iron lev... 1 | 25
increased lean body mass 1 | 107
lethargy 1 | 5
preweaning lethality, complete... 1 | 633
short tibia 1 | 82
small thymus 1 | 11
tremors 1 | 34

Disease

atypical teratoid / rhabdoid tumor 13 | 4,369
ovarian cancer 12 | 8,484
glioblastoma 11 | 5,572
osteosarcoma 11 | 7,933
Carcinoma 10 | 2,147
lung cancer 10 | 4,466
medulloblastoma, large-cell 10 | 6,234
oligodendroglioma 10 | 2,849
pediatric high grade glioma 10 | 2,712
psoriasis 10 | 6,685
lung carcinoma 9 | 2,844
malignant mesothelioma 9 | 3,162
subependymal giant cell astrocytoma 9 | 2,287
Breast cancer 8 | 3,094
interstitial cystitis 7 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,988
invasive ductal carcinoma 7 | 2,950
astrocytic glioma 6 | 2,241
astrocytoma 6 | 1,493
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,956
non-small cell lung cancer 6 | 2,798
pilocytic astrocytoma 6 | 3,086
primitive neuroectodermal tumor 6 | 3,031
sonic hedgehog group medulloblastoma 6 | 1,482
Cancer 5 | 2,346
ependymoma 5 | 2,514
medulloblastoma 5 | 1,524
Pick disease 4 | 1,893
adult high grade glioma 4 | 2,148
breast carcinoma 4 | 1,614
colon cancer 4 | 1,475
cutaneous lupus erythematosus 4 | 1,056
cystic fibrosis 4 | 1,665
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,289
lung adenocarcinoma 4 | 2,713
pancreatic cancer 4 | 2,300
pituitary cancer 4 | 1,972
posterior fossa group A ependymoma 4 | 1,511
spina bifida 4 | 1,064
ulcerative colitis 4 | 2,087
Down syndrome 3 | 548
Rheumatoid Arthritis 3 | 1,160
Schizophrenia 3 | 501
ductal carcinoma in situ 3 | 1,745
interstitial lung disease 3 | 291
tuberculosis 3 | 1,557
Amyotrophic Lateral Sclerosis 2 | 431
Bipolar Disorder 2 | 266
Endometriosis 2 | 535
Intellectual disability 2 | 573
Parkinson's disease 2 | 364
Pelizaeus-Merzbacher disease 2 | 20
adrenocortical carcinoma 2 | 1,427
aldosterone-producing adenoma 2 | 664
diabetes mellitus 2 | 1,663
gastric cancer 2 | 430
glioblastoma multiforme 2 | 347
group 4 medulloblastoma 2 | 1,875
hereditary spastic paraplegia 2 | 313
nephrosclerosis 2 | 329
posterior fossa group B ependymoma 2 | 1,530
primary pancreatic ductal adenocarcinoma 2 | 1,271
AMYOTROPHIC LATERAL SCLEROSIS 1 1 | 49
Acquired metabolic disease 1 | 267
Adenocarcinoma 1 | 115
Alobar Holoprosencephaly 1 | 14
Autistic Disorder 1 | 320
Basal cell carcinoma 1 | 29
Chronic Lymphocytic Leukemia 1 | 242
Cleft Lip 1 | 91
Cleft palate 1 | 125
Common variable immunodeficiency 1 | 72
Congestive heart failure 1 | 30
Craniofacial Abnormalities 1 | 147
Dental caries 1 | 67
Dentin sensitivity 1 | 14
Essential tremor 1 | 30
Familial adenomatous polyposis 1 | 31
Glaucoma 1 | 134
HIV Infections 1 | 100
Hepatitis C 1 | 90
Hirschsprung Disease 1 | 11
Hirschsprung's disease 1 | 42
Holoprosencephaly 1 | 52
Hydrocephalus 1 | 60
Lobar Holoprosencephaly 1 | 14
MASA syndrome 1 | 11
Motor neuron disease 1 | 39
Muscle Weakness 1 | 92
Neutropenia 1 | 78
Nevoid basal cell carcinoma syndrome 1 | 9
Pallister-Hall syndrome 1 | 11
Renal Cell Carcinoma 1 | 199
Rhabdomyosarcoma 1 | 29
SOLITARY MEDIAN MAXILLARY CENTRAL INCISOR 1 | 14
Semilobar Holoprosencephaly 1 | 14
Skin cancer 1 | 37
Sneddon syndrome 1 | 4
Tinea capitis 1 | 12
uncontrolled asthma 1 | 67

Tissue

Blood and immune system 18 | 17,995
Cardiovascular System 18 | 17,958
Digestive Tract 18 | 18,473
Endocrine System 18 | 18,512
Female tissues 18 | 18,647
Liver and Pancreas 18 | 18,136
Male tissues 18 | 17,969
Nervous System 18 | 18,561
Respiratory system 18 | 17,484
Skin and soft tissues 18 | 18,115
Urinary Tract 18 | 18,444

Target Family

Non-IDG 14 | 11,971
Enzyme 2 | 4,146
Ion Channel 1 | 341
Kinase 1 | 634

GO Component

axonal growth cone 18 | 18
nucleus 5,107 | 5,107
cytoplasm 4,985 | 4,985
plasma membrane 4,118 | 4,118
integral component of membrane 3,679 | 3,679
cytosol 3,265 | 3,265
extracellular exosome 2,758 | 2,758
nucleoplasm 2,717 | 2,717
membrane 1,906 | 1,906
extracellular region 1,493 | 1,493
integral component of plasma m... 1,406 | 1,406
extracellular space 1,304 | 1,304
mitochondrion 1,231 | 1,231
Golgi apparatus 864 | 864
endoplasmic reticulum 859 | 859
endoplasmic reticulum membrane 848 | 848
nucleolus 815 | 815
Golgi membrane 659 | 659
perinuclear region of cytoplas... 611 | 611
cell surface 594 | 594
intracellular 548 | 548
intracellular membrane-bounded... 537 | 537
cell junction 451 | 451
mitochondrial inner membrane 425 | 425
centrosome 409 | 409
focal adhesion 383 | 383
protein complex 355 | 355
cytoskeleton 343 | 343
dendrite 329 | 329
mitochondrial matrix 322 | 322
cell-cell adherens junction 307 | 307
neuronal cell body 303 | 303
microtubule 294 | 294
lysosomal membrane 278 | 278
apical plasma membrane 277 | 277
proteinaceous extracellular ma... 244 | 244
neuron projection 229 | 229
nuclear membrane 218 | 218
early endosome 217 | 217
axon 214 | 214
lysosome 210 | 210
endosome 208 | 208
actin cytoskeleton 205 | 205
external side of plasma membra... 205 | 205
postsynaptic membrane 204 | 204
extracellular matrix 198 | 198
nuclear speck 197 | 197
membrane raft 196 | 196
endoplasmic reticulum lumen 192 | 192
transcription factor complex 184 | 184
endosome membrane 182 | 182
early endosome membrane 180 | 180
basolateral plasma membrane 174 | 174
nuclear chromatin 169 | 169
synapse 166 | 166
cell-cell junction 161 | 161
nuclear envelope 156 | 156
lamellipodium 153 | 153
mitochondrial outer membrane 148 | 148
blood microparticle 147 | 147
myelin sheath 144 | 144
postsynaptic density 144 | 144
cytoplasmic vesicle 143 | 143
microtubule organizing center 137 | 137
cytoplasmic, membrane-bounded ... 132 | 132
ER to Golgi transport vesicle ... 131 | 131
microtubule cytoskeleton 127 | 127
receptor complex 127 | 127
phagocytic vesicle membrane 126 | 126
cytoplasmic vesicle membrane 125 | 125
midbody 125 | 125
trans-Golgi network 124 | 124
cell cortex 119 | 119
cilium 118 | 118
late endosome 116 | 116
spindle 116 | 116
intracellular ribonucleoprotei... 114 | 114
vesicle 112 | 112
Z disc 110 | 110
bicellular tight junction 110 | 110
anchored component of membrane 109 | 109
growth cone 109 | 109
integral component of lumenal ... 108 | 108
late endosome membrane 107 | 107
endomembrane system 106 | 106
centriole 105 | 105
recycling endosome 104 | 104
spindle pole 104 | 104
perikaryon 103 | 103
integral component of endoplas... 101 | 101
intermediate filament 101 | 101
melanosome 101 | 101
chromosome 100 | 100
dendritic spine 99 | 99
ubiquitin ligase complex 99 | 99
peroxisome 98 | 98
nuclear matrix 97 | 97
PML body 94 | 94
Golgi lumen 93 | 93
keratin filament 93 | 93
trans-Golgi network membrane 92 | 92

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Reticulon-4 receptor RTN4R Tbio Non-IDG -2.54684 385.1 166
Protein cordon-bleu COBL Tbio Non-IDG -1.38380 26.9 78
CLIP-associating protein 2 CLASP2 Tbio Non-IDG -1.22296 20.8 220
Shootin-1 SHTN1 Tbio Non-IDG -0.97772 9.81 24
C-Jun-amino-terminal kinase-interacting protein 1 MAPK8IP1 Tbio Enzyme -2.80392 652.2 146
Neuronal membrane glycoprotein M6-a GPM6A Tbio Non-IDG -1.22785 24.2 158
Noelin OLFM1 Tbio Non-IDG -1.32290 24.7 286
Protein patched homolog 1 PTCH1 Tbio Non-IDG -3.09626 1236.4 412
Ephrin type-A receptor 4 EPHA4 Tchem Kinase -2.31936 234.5 411
Peptidyl-prolyl cis-trans isomerase FKBP4 FKBP4 Tchem Enzyme -2.67831 516.8 409