Development Level

Tbio 33 | 11,445
Tclin 13 | 613
Tchem 4 | 1,598
Tdark 1 | 6,588

Collection

Ion Channel: IDG Consortium (T... 3 | 99

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal behavior 2 | 298
decreased circulating triglyce... 2 | 79
hypoactivity 2 | 132
increased circulating alkaline... 2 | 122
increased mean corpuscular vol... 2 | 92
abnormal coat appearance 1 | 31
abnormal kidney morphology 1 | 65
abnormal pancreas morphology 1 | 13
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
absent testes 1 | 6
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased bone mineral content 1 | 151
decreased circulating glucose ... 1 | 126
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged uterus 1 | 11
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased IgG2b level 1 | 1
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating potassiu... 1 | 29
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased erythrocyte cell num... 1 | 39
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
short tibia 1 | 97
shortened QRS complex duration 1 | 1
small superior vagus ganglion 1 | 74
tremors 1 | 39

Disease

Carcinoma 36 | 11,493
glioblastoma 32 | 5,792
ependymoma 29 | 4,679
medulloblastoma, large-cell 28 | 6,241
atypical teratoid / rhabdoid tumor 26 | 5,112
Astrocytoma, Pilocytic 25 | 3,081
adult high grade glioma 24 | 3,801
osteosarcoma 24 | 7,950
oligodendroglioma 23 | 2,850
group 3 medulloblastoma 21 | 4,104
psoriasis 20 | 6,694
astrocytic glioma 18 | 2,597
ovarian cancer 18 | 8,520
lung cancer 17 | 4,740
primitive neuroectodermal tumor 16 | 3,035
Depressive disorder 15 | 409
Epilepsy 14 | 792
Bipolar Disorder 12 | 666
Breast cancer 12 | 3,578
Mood Disorders 12 | 184
Schizophrenia 12 | 1,160
lung carcinoma 12 | 2,843
malignant mesothelioma 12 | 3,232
Alcoholic Intoxication, Chronic 11 | 289
Cancer 11 | 2,499
Mental Depression 11 | 333
Seizures 11 | 596
cystic fibrosis 11 | 1,696
lung adenocarcinoma 11 | 2,716
Kidney cancer 10 | 2,613
Parkinson's disease 10 | 392
Pick disease 10 | 1,894
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
non-small cell lung cancer 10 | 2,890
subependymal giant cell astrocytoma 10 | 2,287
Major Depressive Disorder 9 | 301
astrocytoma 9 | 1,146
Obesity 8 | 678
Opiate dependence 8 | 29
Pain 8 | 103
Pain agnosia 8 | 104
Unipolar Depression 8 | 250
Alcohol dependence 7 | 107
Alzheimer's disease 7 | 658
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
invasive ductal carcinoma 7 | 2,951
pediatric high grade glioma 7 | 1,064
pituitary cancer 7 | 1,972
ulcerative colitis 7 | 1,819
Autosomal recessive predisposition 6 | 1,442
Bradycardia 6 | 36
General anesthesia 6 | 53
Hypertension 6 | 396
Intellectual disability 6 | 1,016
Multiple Sclerosis 6 | 540
Muscle hypotonia 6 | 571
adrenocortical carcinoma 6 | 1,428
diabetes mellitus 6 | 1,728
group 4 medulloblastoma 6 | 1,855
interstitial cystitis 6 | 2,312
pancreatic cancer 6 | 2,398
Anxiety 5 | 136
Anxiety disease 5 | 113
Autistic Disorder 5 | 364
Cocaine-Related Disorders 5 | 92
Hypertensive disease 5 | 292
Hypotension 5 | 82
Liver Cirrhosis, Experimental 5 | 769
Melanoma 5 | 711
Skin cancer 5 | 469
Urinary Incontinence 5 | 50
breast carcinoma 5 | 1,638
colon cancer 5 | 1,478
juvenile dermatomyositis 5 | 1,187
primary pancreatic ductal adenocarcinoma 5 | 1,109
Adenoma 4 | 167
Allergic rhinitis 4 | 94
Amyotrophic lateral sclerosis 4 | 451
Asthma 4 | 385
Cerebral atrophy 4 | 178
Cognitive delay 4 | 608
Constipation 4 | 181
Down syndrome 4 | 499
Dyskinesia, Drug-Induced 4 | 15
Eaton-Lambert syndrome 4 | 40
Gastroesophageal reflux disease 4 | 110
Gastrointestinal Radiography Adjunct 4 | 11
Global developmental delay 4 | 608
Huntington's disease 4 | 76
Hyperactive behavior 4 | 91
Hyperalgesia 4 | 83
Hyperreflexia 4 | 209
Kidney disease 4 | 430
Mental and motor retardation 4 | 608
Multiple myeloma 4 | 1,332
Small testicle 4 | 75
Vascular disease 4 | 319
ductal carcinoma in situ 4 | 1,745
non primary Sjogren syndrome sicca 4 | 891

Tissue

Endocrine System 50 | 18,159
Female tissues 50 | 17,400
Digestive Tract 49 | 17,369
Liver and Pancreas 49 | 16,750
Male tissues 48 | 17,142
Nervous System 47 | 16,725
Skin and soft tissues 47 | 17,230
Urinary Tract 47 | 16,678
Respiratory system 46 | 16,393
Blood and immune system 41 | 16,909
Cardiovascular System 41 | 15,192

Target Family

Non-IDG 19 | 12,091
Enzyme 10 | 4,145
GPCR 9 | 408
Ion Channel 6 | 344
Kinase 2 | 634
Transcription Factor 2 | 1,400
Transporter 2 | 473
Epigenetic 1 | 242

GO Component

axon terminus 51 | 51
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Aquaporin-1 AQP1 Tbio Non-IDG -3.08125 1107.4 374
Potassium voltage-gated channel subfamily A member 2 KCNA2 Tclin Ion Channel -2.55550 343.3 205
Calsenilin KCNIP3 Tbio Ion Channel -1.72310 56.0 369
Pro-FMRFamide-related neuropeptide FF NPFF Tbio Non-IDG -2.47334 319.6 96
Leucine-rich repeat transmembrane protein FLRT3 FLRT3 Tbio Non-IDG -1.29335 20.6 58
Neurotensin/neuromedin N NTS Tbio Non-IDG -3.56154 3627.6 183
Sorcin SRI Tbio Non-IDG -2.69915 481.5 119
C-C motif chemokine 2 CCL2 Tchem Non-IDG -3.84820 7088.3 1260
Potassium voltage-gated channel subfamily A member 1 KCNA1 Tclin Ion Channel -2.59564 379.1 313
Muscarinic acetylcholine receptor M1 CHRM1 Tclin GPCR -2.16159 140.8 222