Development Level

Tbio 33 | 11,445
Tchem 4 | 1,598
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 7 | 979
hemorrhage 4 | 23
abnormal embryo size 3 | 220
increased or absent threshold ... 3 | 101
hyperactivity 2 | 148
increased body length 2 | 32
increased heart rate 2 | 23
prenatal lethality prior to he... 2 | 87
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal facial morphology 1 | 17
abnormal head shape 1 | 10
abnormal iris pigmentation 1 | 4
abnormal limb bud morphology 1 | 17
abnormal limb morphology 1 | 13
abnormal outer ear morphology 1 | 3
abnormal pericardium morpholog... 1 | 26
abnormal placenta size 1 | 20
abnormal retina morphology 1 | 71
abnormal spine curvature 1 | 9
abnormal tail morphology 1 | 25
convulsive seizures 1 | 13
cyanosis 1 | 7
decreased bone mineral content 1 | 151
decreased cardiac muscle contr... 1 | 11
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased red blood cell distr... 1 | 41
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased cardiac muscle contr... 1 | 8
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating chloride... 1 | 41
increased circulating glucose ... 1 | 24
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased lean body mass 1 | 172
pale liver 1 | 6
polycystic kidney 1 | 15
prenatal lethality 1 | 28
preweaning lethality, incomple... 1 | 499
shortened RR interval 1 | 17
small superior vagus ganglion 1 | 74

Disease

Carcinoma 25 | 11,493
ovarian cancer 23 | 8,520
atypical teratoid / rhabdoid tumor 21 | 5,112
medulloblastoma, large-cell 20 | 6,241
osteosarcoma 20 | 7,950
glioblastoma 19 | 5,792
adult high grade glioma 17 | 3,801
ependymoma 15 | 4,679
oligodendroglioma 14 | 2,850
Astrocytoma, Pilocytic 12 | 3,081
Breast cancer 11 | 3,578
Schizophrenia 11 | 1,160
astrocytic glioma 11 | 2,597
psoriasis 11 | 6,694
Neurodegenerative disease 10 | 414
Pick disease 10 | 1,894
group 3 medulloblastoma 10 | 4,104
Autosomal recessive predisposition 9 | 1,442
Hermansky-Pudlak syndrome 9 | 42
lung cancer 9 | 4,740
subependymal giant cell astrocytoma 9 | 2,287
group 4 medulloblastoma 8 | 1,855
non-small cell lung cancer 8 | 2,890
primitive neuroectodermal tumor 8 | 3,035
Neuropathy 7 | 261
Platelet storage pool deficiency 7 | 21
hereditary spastic paraplegia 7 | 318
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
lung adenocarcinoma 7 | 2,716
pancreatic cancer 7 | 2,398
pituitary cancer 7 | 1,972
tuberculosis 7 | 2,010
Hyperreflexia 6 | 209
Nystagmus 6 | 317
adrenocortical carcinoma 6 | 1,428
colon cancer 6 | 1,478
lung carcinoma 6 | 2,843
malignant mesothelioma 6 | 3,232
Absent reflex 5 | 92
Absent tendon reflex 5 | 92
Alzheimer's disease 5 | 658
Babinski Reflex 5 | 100
Bipolar Disorder 5 | 666
Cancer 5 | 2,499
Intellectual disability 5 | 1,016
Kidney cancer 5 | 2,613
Reflex, Deep Tendon, Absent 5 | 92
diabetes mellitus 5 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
medulloblastoma 5 | 720
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Amyotrophic lateral sclerosis 4 | 451
Atrophy of cerebellum 4 | 103
Cerebellar degeneration 4 | 103
Cerebral atrophy 4 | 178
Congenital pes cavus 4 | 88
Decreased tendon reflex 4 | 122
Depressive disorder 4 | 409
Dull intelligence 4 | 645
Heart failure 4 | 162
Hermanski-Pudlak Syndrome 4 | 8
Highly variable severity 4 | 157
Infratentorial atrophy 4 | 103
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Multiple myeloma 4 | 1,332
Optic Atrophy 4 | 242
Peripheral Neuropathy 4 | 134
Poor school performance 4 | 645
Rheumatoid arthritis 4 | 1,191
Variable expressivity 4 | 157
Vascular disease 4 | 319
acute myeloid leukemia 4 | 783
aldosterone-producing adenoma 4 | 665
primary pancreatic ductal adenocarcinoma 4 | 1,109
Atopic dermatitis 3 | 952
Chronic progressive external ophthalmoplegia 3 | 26
Decreased number of large and small myelinated fibers 3 | 20
Distal limb muscle weakness due to peripheral neuropathy 3 | 62
Distal muscle weakness 3 | 62
Down syndrome 3 | 499
Epilepsy 3 | 792
Liver cancer 3 | 604
Major Depressive Disorder 3 | 301
Mental Depression 3 | 333
Paraplegia 3 | 74
Parkinson's disease 3 | 392
Progressive disorder 3 | 142
Proteinuria 3 | 144
Slow progression 3 | 89
Unipolar Depression 3 | 250
breast carcinoma 3 | 1,638
cystic fibrosis 3 | 1,696
dermatomyositis 3 | 966
esophageal adenocarcinoma 3 | 737
invasive ductal carcinoma 3 | 2,951
nasopharyngeal carcinoma 3 | 1,058
ulcerative colitis 3 | 1,819

Tissue

Blood and immune system 39 | 16,909
Digestive Tract 39 | 17,369
Endocrine System 39 | 18,159
Female tissues 39 | 17,400
Liver and Pancreas 39 | 16,750
Male tissues 39 | 17,142
Nervous System 39 | 16,725
Respiratory system 39 | 16,393
Skin and soft tissues 39 | 17,230
Urinary Tract 39 | 16,678
Cardiovascular System 36 | 15,192

Target Family

Non-IDG 32 | 12,091
Enzyme 6 | 4,145
Transcription Factor 1 | 1,400

GO Component

axon cytoplasm 39 | 39
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ras-related protein Rab-21 RAB21 Tbio Enzyme -1.33715 23.1 275
Biogenesis of lysosome-related organelles complex 1 subunit 4 BLOC1S4 Tdark Non-IDG 0.00000 53
Biogenesis of lysosome-related organelles complex 1 subunit 2 BLOC1S2 Tbio Non-IDG -2.89123 759.6 79
Biogenesis of lysosome-related organelles complex 1 subunit 3 BLOC1S3 Tbio Non-IDG -0.81676 0.00000 66
Biogenesis of lysosome-related organelles complex 1 subunit 1 BLOC1S1 Tbio Non-IDG -1.17005 16.2 49
Kinesin-like protein KIF1A KIF1A Tbio Non-IDG -2.11552 130.9 37
Heat shock protein beta-1 HSPB1 Tchem Non-IDG -2.97780 974.9 1992
Ran GTPase-activating protein 1 RANGAP1 Tbio Enzyme -1.84078 65.7 254
Tripartite motif-containing protein 46 TRIM46 Tbio Non-IDG -1.51367 30.5 78
AP-3 complex subunit beta-1 AP3B1 Tbio Non-IDG -1.27699 21.0 89