Development Level

Tbio 174 | 11,651
Tchem 32 | 1,388
Tclin 32 | 612
Tdark 12 | 6,593

Collection

RFA-RM-18-021 4 | 328
Ion Channel: IDG Consortium (T... 3 | 99
Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 16 | 979
abnormal behavior 11 | 298
preweaning lethality, incomple... 11 | 499
hyperactivity 6 | 148
abnormal bone structure 5 | 187
decreased bone mineral content 5 | 151
decreased startle reflex 4 | 75
decreased vertical activity 4 | 208
impaired glucose tolerance 4 | 75
small superior vagus ganglion 4 | 74
abnormal locomotor behavior 3 | 24
abnormal retina morphology 3 | 71
decreased grip strength 3 | 116
decreased heart weight 3 | 27
decreased mean corpuscular vol... 3 | 79
edema 3 | 59
hypoactivity 3 | 132
increased blood urea nitrogen ... 3 | 48
increased circulating choleste... 3 | 66
increased circulating sodium l... 3 | 71
increased circulating triglyce... 3 | 42
increased or absent threshold ... 3 | 101
increased total body fat amoun... 3 | 134
prenatal lethality prior to he... 3 | 87
abnormal cornea morphology 2 | 31
abnormal embryo size 2 | 220
abnormal gait 2 | 69
abnormal seminal vesicle morph... 2 | 114
decreased bone mineral density 2 | 126
decreased caudal vertebrae num... 2 | 53
decreased circulating alanine ... 2 | 47
decreased circulating aspartat... 2 | 34
decreased circulating phosphat... 2 | 27
decreased circulating serum al... 2 | 82
decreased heart left ventricle... 2 | 28
decreased lean body mass 2 | 135
decreased lymphocyte cell numb... 2 | 83
decreased neutrophil cell numb... 2 | 42
embryonic lethality prior to o... 2 | 239
enlarged heart 2 | 210
improved glucose tolerance 2 | 79
increased circulating HDL chol... 2 | 80
increased circulating alkaline... 2 | 122
increased heart weight 2 | 62
increased mean corpuscular vol... 2 | 92
increased neutrophil cell numb... 2 | 46
increased startle reflex 2 | 112
prenatal lethality 2 | 28
thin ventricular wall 2 | 24
abnormal embryo turning 1 | 31
abnormal hair growth 1 | 10
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal pancreas morphology 1 | 13
abnormal skin coloration 1 | 25
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
abnormal spleen morphology 1 | 55
abnormal vocalization 1 | 21
absent spleen 1 | 3
brachydactyly 1 | 19
cataract 1 | 92
decreased T cell number 1 | 15
decreased circulating bilirubi... 1 | 19
decreased circulating chloride... 1 | 30
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased hemoglobin content 1 | 68
decreased pulmonary respirator... 1 | 5
decreased red blood cell distr... 1 | 41
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
enlarged uterus 1 | 11
hemorrhage 1 | 23
hydrometra 1 | 53
impaired righting response 1 | 26
increased bone mineral content 1 | 108
increased cardiac muscle contr... 1 | 8
increased circulating alanine ... 1 | 13
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating potassiu... 1 | 29
increased circulating total pr... 1 | 28
increased fasted circulating g... 1 | 76
increased lean body mass 1 | 172
increased mean platelet volume 1 | 45
increased prepulse inhibition 1 | 32
increased vertical activity 1 | 24
limb grasping 1 | 41
microphthalmia 1 | 26
persistence of hyaloid vascula... 1 | 33
premature death 1 | 5
small kidney 1 | 16
small testis 1 | 58
syndactyly 1 | 23
thrombocytosis 1 | 27
tremors 1 | 39
trunk curl 1 | 16

Disease

Carcinoma 187 | 11,493
medulloblastoma, large-cell 140 | 6,241
glioblastoma 138 | 5,792
atypical teratoid / rhabdoid tumor 129 | 5,112
ependymoma 124 | 4,679
osteosarcoma 124 | 7,950
ovarian cancer 115 | 8,520
adult high grade glioma 113 | 3,801
group 3 medulloblastoma 99 | 4,104
psoriasis 91 | 6,694
Astrocytoma, Pilocytic 90 | 3,081
oligodendroglioma 85 | 2,850
lung cancer 84 | 4,740
astrocytic glioma 81 | 2,597
Kidney cancer 80 | 2,613
primitive neuroectodermal tumor 75 | 3,035
Breast cancer 70 | 3,578
lung carcinoma 68 | 2,843
Cancer 66 | 2,499
Schizophrenia 66 | 1,160
malignant mesothelioma 63 | 3,232
Pick disease 62 | 1,894
subependymal giant cell astrocytoma 48 | 2,287
intraductal papillary-mucinous adenoma (IPMA) 46 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 46 | 3,291
lung adenocarcinoma 46 | 2,716
Bipolar Disorder 45 | 666
pituitary cancer 45 | 1,972
invasive ductal carcinoma 44 | 2,951
non-small cell lung cancer 44 | 2,890
intraductal papillary-mucinous carcinoma (IPMC) 41 | 2,989
Alzheimer's disease 37 | 658
Depressive disorder 37 | 409
Neurodegenerative disease 37 | 414
colon cancer 36 | 1,478
cystic fibrosis 36 | 1,696
group 4 medulloblastoma 34 | 1,855
Intellectual disability 33 | 1,016
interstitial cystitis 33 | 2,312
tuberculosis 33 | 2,010
Epilepsy 32 | 792
Liver cancer 31 | 604
Parkinson's disease 31 | 392
pancreatic cancer 31 | 2,398
Autosomal recessive predisposition 30 | 1,442
ulcerative colitis 30 | 1,819
Mental Depression 29 | 333
Alcoholic Intoxication, Chronic 28 | 289
Cognitive delay 27 | 608
Global developmental delay 27 | 608
Mental and motor retardation 27 | 608
Amyotrophic lateral sclerosis 26 | 451
breast carcinoma 26 | 1,638
ductal carcinoma in situ 26 | 1,745
Seizures 24 | 596
Major Depressive Disorder 23 | 301
Melanoma 23 | 711
adrenocortical carcinoma 23 | 1,428
cutaneous lupus erythematosus 23 | 1,057
Autistic Disorder 22 | 364
Down syndrome 22 | 499
juvenile dermatomyositis 22 | 1,187
Mood Disorders 21 | 184
Skin cancer 21 | 469
diabetes mellitus 21 | 1,728
Dull intelligence 20 | 645
Low intelligence 20 | 645
Mental Retardation 20 | 645
Mental deficiency 20 | 645
Poor school performance 20 | 645
astrocytoma 20 | 1,146
Neuropathy 19 | 261
Toxic encephalopathy 19 | 141
active Crohn's disease 19 | 922
Dementia 18 | 175
Multiple myeloma 18 | 1,332
Obesity 18 | 678
Unipolar Depression 18 | 250
Rheumatoid arthritis 17 | 1,191
medulloblastoma 17 | 720
nasopharyngeal carcinoma 17 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 17 | 1,962
Attention deficit hyperactivity disorder 16 | 278
Cocaine-Related Disorders 16 | 92
Multiple Sclerosis 16 | 540
aldosterone-producing adenoma 16 | 665
spina bifida 16 | 1,074
Atopic dermatitis 15 | 952
Muscle hypotonia 15 | 571
Nerve Degeneration 15 | 121
Prostatic Neoplasms 15 | 495
Waldenstrons macroglobulinemia 15 | 765
dermatomyositis 15 | 966
active ulcerative colitis 14 | 764
progressive supranuclear palsy 14 | 676
Endometriosis 13 | 540
Infantile onset 13 | 238
Vascular disease 13 | 319
acute quadriplegic myopathy 13 | 1,158
pediatric high grade glioma 13 | 1,064

Tissue

Endocrine System 248 | 18,159
Female tissues 246 | 17,400
Digestive Tract 244 | 17,369
Male tissues 243 | 17,142
Nervous System 243 | 16,725
Skin and soft tissues 243 | 17,230
Urinary Tract 238 | 16,678
Liver and Pancreas 237 | 16,750
Respiratory system 234 | 16,393
Blood and immune system 233 | 16,909
Cardiovascular System 216 | 15,192

Target Family

Non-IDG 145 | 12,091
Enzyme 41 | 4,145
Kinase 20 | 634
Ion Channel 17 | 344
GPCR 14 | 408
Transporter 6 | 473
Transcription Factor 4 | 1,400
Epigenetic 3 | 242

GO Component

axon 250 | 250
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Atlastin-1 ATL1 Tbio Non-IDG -2.07795 119.7 164
Integrin alpha-2 ITGA2 Tbio Non-IDG -2.58423 335.9 895
Serine/threonine-protein kinase PAK 1 PAK1 Tchem Kinase -2.29299 237.8 1060
Sodium channel protein type 2 subunit alpha SCN2A Tclin Ion Channel -3.11580 1268.8 107
Metabotropic glutamate receptor 2 GRM2 Tchem GPCR -2.77035 612.3 315
Neurotrypsin PRSS12 Tbio Non-IDG -1.46986 30.6 77
Myotubularin-related protein 2 MTMR2 Tbio Enzyme -1.64906 46.5 124
Disintegrin and metalloproteinase domain-containing protein 21 ADAM21 Tdark Enzyme -0.76419 6.37 28
Roundabout homolog 1 ROBO1 Tbio Non-IDG -2.15518 129.8 261
Neuritin-like protein NRN1L Tdark Non-IDG 0.70 0.20 71