Development Level

Tbio 144 | 10,625
Tchem 37 | 1,890
Tclin 25 | 602
Tdark 8 | 7,003

Collection

Eligible Ion Channel Proteins 2 | 117
Eligible Kinase Proteins 1 | 134
Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

preweaning lethality, complete... 12 | 633
abnormal behavior 8 | 226
preweaning lethality, incomple... 7 | 260
decreased bone mineral content 5 | 157
decreased lean body mass 4 | 195
hyperactivity 4 | 108
prenatal lethality prior to he... 4 | 64
decreased grip strength 3 | 123
decreased startle reflex 3 | 48
increased body weight 3 | 42
increased circulating HDL chol... 3 | 63
increased circulating choleste... 3 | 53
increased circulating sodium l... 3 | 71
abnormal QRS complex 2 | 25
abnormal bone structure 2 | 131
abnormal coping response 2 | 12
abnormal lens morphology 2 | 73
abnormal retina morphology 2 | 100
abnormal retinal blood vessel ... 2 | 18
decreased lymphocyte cell numb... 2 | 9
decreased rib number 2 | 59
edema 2 | 11
hemorrhage 2 | 12
improved glucose tolerance 2 | 56
increased blood urea nitrogen ... 2 | 44
increased circulating alkaline... 2 | 119
increased exploration in new e... 2 | 56
increased grip strength 2 | 83
increased heart weight 2 | 37
increased lean body mass 2 | 107
increased mean corpuscular vol... 2 | 91
increased neutrophil cell numb... 2 | 15
increased or absent threshold ... 2 | 128
male infertility 2 | 62
prenatal lethality 2 | 16
abnormal coat/hair pigmentatio... 1 | 54
abnormal cornea morphology 1 | 24
abnormal digit morphology 1 | 13
abnormal femur morphology 1 | 14
abnormal gait 1 | 51
abnormal heart morphology 1 | 51
abnormal kidney morphology 1 | 30
abnormal limb bud morphology 1 | 15
abnormal placenta size 1 | 10
abnormal retinal pigmentation 1 | 61
abnormal retinal vasculature m... 1 | 15
abnormal skin coloration 1 | 18
abnormal sleep behavior 1 | 63
abnormal spleen morphology 1 | 36
abnormal stomach morphology 1 | 4
abnormal tail morphology 1 | 17
abnormal tooth morphology 1 | 24
absent teeth 1 | 4
cyanosis 1 | 6
decreased CD4-positive, CD25-p... 1 | 24
decreased CD8-positive, alpha-... 1 | 26
decreased T cell number 1 | 31
decreased basophil cell number 1 | 11
decreased bone mineral density 1 | 126
decreased circulating bilirubi... 1 | 14
decreased circulating chloride... 1 | 32
decreased circulating phosphat... 1 | 15
decreased circulating serum al... 1 | 79
decreased circulating triglyce... 1 | 83
decreased eosinophil cell numb... 1 | 41
decreased heart weight 1 | 44
decreased hemoglobin content 1 | 53
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular vol... 1 | 50
decreased prepulse inhibition 1 | 52
decreased pulmonary respirator... 1 | 4
decreased total retina thickne... 1 | 20
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
enlarged lymph nodes 1 | 27
hydrops fetalis 1 | 22
impaired glucose tolerance 1 | 52
increased caudal vertebrae num... 1 | 8
increased circulating alanine ... 1 | 11
increased circulating chloride... 1 | 43
increased circulating creatini... 1 | 29
increased circulating potassiu... 1 | 31
increased circulating serum al... 1 | 25
increased erythrocyte cell num... 1 | 26
increased fasted circulating g... 1 | 68
increased mean corpuscular hem... 1 | 93
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
increased vertical activity 1 | 18
persistence of hyaloid vascula... 1 | 22
polycystic kidney 1 | 9
premature death 1 | 5
respiratory system phenotype 1 | 2
small kidney 1 | 10
small superior vagus ganglion 1 | 20
small testis 1 | 37
sparse hair 1 | 6
straub tail 1 | 26
thrombocytosis 1 | 23
trunk curl 1 | 15

Disease

medulloblastoma, large-cell 125 | 6,234
glioblastoma 117 | 5,572
osteosarcoma 102 | 7,933
ovarian cancer 102 | 8,484
atypical teratoid / rhabdoid tumor 99 | 4,369
psoriasis 86 | 6,685
pilocytic astrocytoma 79 | 3,086
oligodendroglioma 75 | 2,849
primitive neuroectodermal tumor 71 | 3,031
lung cancer 67 | 4,466
Carcinoma 60 | 2,147
astrocytic glioma 60 | 2,241
ependymoma 59 | 2,514
lung carcinoma 59 | 2,844
pediatric high grade glioma 55 | 2,712
Pick disease 54 | 1,893
Cancer 53 | 2,346
malignant mesothelioma 53 | 3,162
adult high grade glioma 52 | 2,148
Breast cancer 51 | 3,094
medulloblastoma 44 | 1,524
subependymal giant cell astrocytoma 42 | 2,287
intraductal papillary-mucinous adenoma (IPMA) 41 | 2,956
pituitary cancer 41 | 1,972
group 4 medulloblastoma 40 | 1,875
invasive ductal carcinoma 40 | 2,950
intraductal papillary-mucinous neoplasm (IPMN) 39 | 3,289
lung adenocarcinoma 39 | 2,713
intraductal papillary-mucinous carcinoma (IPMC) 37 | 2,988
non-small cell lung cancer 36 | 2,798
Schizophrenia 35 | 501
Alzheimer's disease 32 | 644
astrocytoma 32 | 1,493
ulcerative colitis 32 | 2,087
colon cancer 31 | 1,475
cystic fibrosis 31 | 1,665
Neurodegenerative disease 30 | 383
posterior fossa group A ependymoma 30 | 1,511
posterior fossa group B ependymoma 29 | 1,530
group 3 medulloblastoma 28 | 2,254
interstitial cystitis 28 | 2,299
tuberculosis 27 | 1,557
Parkinson's disease 26 | 364
ductal carcinoma in situ 25 | 1,745
sonic hedgehog group medulloblastoma 25 | 1,482
atypical teratoid/rhabdoid tumor 24 | 1,095
pancreatic cancer 24 | 2,300
breast carcinoma 22 | 1,614
cutaneous lupus erythematosus 22 | 1,056
Autistic Disorder 21 | 320
Down syndrome 21 | 548
Obesity 20 | 616
juvenile dermatomyositis 20 | 1,189
Epilepsy 19 | 346
active Crohn's disease 19 | 918
diabetes mellitus 19 | 1,663
Amyotrophic Lateral Sclerosis 18 | 431
Neuropathy 18 | 210
adrenocortical carcinoma 18 | 1,427
Bipolar Disorder 17 | 266
Dementia 17 | 129
Intellectual disability 17 | 573
Toxic encephalopathy 17 | 131
pancreatic ductal adenocarcinoma liver metastasis 17 | 1,795
Multiple myeloma 16 | 1,327
nasopharyngeal carcinoma 15 | 1,056
Cocaine-Related Disorders 14 | 88
Multiple Sclerosis 14 | 498
dermatomyositis 14 | 933
spina bifida 14 | 1,064
Alcohol dependence 13 | 107
Atopic dermatitis 13 | 944
Endometriosis 13 | 535
Prostatic Neoplasms 13 | 471
Waldenstrons macroglobulinemia 13 | 765
aldosterone-producing adenoma 13 | 664
Major Depressive Disorder 12 | 106
Rheumatoid Arthritis 12 | 1,160
acute quadriplegic myopathy 12 | 1,157
tuberculosis and treatment for 6 months 12 | 686
Attention deficit hyperactivity disorder 11 | 156
Melanoma 11 | 261
Nerve Degeneration 11 | 73
Vascular disease 11 | 281
esophageal adenocarcinoma 11 | 737
hereditary spastic paraplegia 11 | 313
non-small cell lung carcinoma 11 | 413
primary pancreatic ductal adenocarcinoma 11 | 1,271
progressive supranuclear palsy 11 | 674
Mammary Neoplasms 10 | 410
Osteoporosis 10 | 257
Parkinson Disease 10 | 102
Substance abuse 10 | 55
fibroadenoma 10 | 557
gastric carcinoma 10 | 832
Panic disorder 9 | 55
Peripheral Neuropathy 9 | 303
Seizures 9 | 95
sarcoidosis 9 | 358
Duchenne muscular dystrophy 8 | 602

Tissue

Blood and immune system 214 | 17,995
Cardiovascular System 214 | 17,958
Digestive Tract 214 | 18,473
Endocrine System 214 | 18,512
Female tissues 214 | 18,647
Nervous System 214 | 18,561
Respiratory system 214 | 17,484
Male tissues 213 | 17,969
Liver and Pancreas 212 | 18,136
Urinary Tract 212 | 18,444
Skin and soft tissues 211 | 18,115

Target Family

Non-IDG 123 | 11,971
Enzyme 37 | 4,146
Kinase 18 | 634
Ion Channel 12 | 341
GPCR 11 | 406
Transporter 6 | 473
Transcription Factor 4 | 1,400
Epigenetic 3 | 242

GO Component

axon 214 | 214
nucleus 5,107 | 5,107
cytoplasm 4,985 | 4,985
plasma membrane 4,118 | 4,118
integral component of membrane 3,679 | 3,679
cytosol 3,265 | 3,265
extracellular exosome 2,758 | 2,758
nucleoplasm 2,717 | 2,717
membrane 1,906 | 1,906
extracellular region 1,493 | 1,493
integral component of plasma m... 1,406 | 1,406
extracellular space 1,304 | 1,304
mitochondrion 1,231 | 1,231
Golgi apparatus 864 | 864
endoplasmic reticulum 859 | 859
endoplasmic reticulum membrane 848 | 848
nucleolus 815 | 815
Golgi membrane 659 | 659
perinuclear region of cytoplas... 611 | 611
cell surface 594 | 594
intracellular 548 | 548
intracellular membrane-bounded... 537 | 537
cell junction 451 | 451
mitochondrial inner membrane 425 | 425
centrosome 409 | 409
focal adhesion 383 | 383
protein complex 355 | 355
cytoskeleton 343 | 343
dendrite 329 | 329
mitochondrial matrix 322 | 322
cell-cell adherens junction 307 | 307
neuronal cell body 303 | 303
microtubule 294 | 294
lysosomal membrane 278 | 278
apical plasma membrane 277 | 277
proteinaceous extracellular ma... 244 | 244
neuron projection 229 | 229
nuclear membrane 218 | 218
early endosome 217 | 217
lysosome 210 | 210
endosome 208 | 208
actin cytoskeleton 205 | 205
external side of plasma membra... 205 | 205
postsynaptic membrane 204 | 204
extracellular matrix 198 | 198
nuclear speck 197 | 197
membrane raft 196 | 196
endoplasmic reticulum lumen 192 | 192
transcription factor complex 184 | 184
endosome membrane 182 | 182
early endosome membrane 180 | 180
basolateral plasma membrane 174 | 174
nuclear chromatin 169 | 169
synapse 166 | 166
cell-cell junction 161 | 161
nuclear envelope 156 | 156
lamellipodium 153 | 153
mitochondrial outer membrane 148 | 148
blood microparticle 147 | 147
myelin sheath 144 | 144
postsynaptic density 144 | 144
cytoplasmic vesicle 143 | 143
microtubule organizing center 137 | 137
cytoplasmic, membrane-bounded ... 132 | 132
ER to Golgi transport vesicle ... 131 | 131
microtubule cytoskeleton 127 | 127
receptor complex 127 | 127
phagocytic vesicle membrane 126 | 126
cytoplasmic vesicle membrane 125 | 125
midbody 125 | 125
trans-Golgi network 124 | 124
cell cortex 119 | 119
cilium 118 | 118
late endosome 116 | 116
spindle 116 | 116
intracellular ribonucleoprotei... 114 | 114
vesicle 112 | 112
Z disc 110 | 110
bicellular tight junction 110 | 110
anchored component of membrane 109 | 109
growth cone 109 | 109
integral component of lumenal ... 108 | 108
late endosome membrane 107 | 107
endomembrane system 106 | 106
centriole 105 | 105
recycling endosome 104 | 104
spindle pole 104 | 104
perikaryon 103 | 103
integral component of endoplas... 101 | 101
intermediate filament 101 | 101
melanosome 101 | 101
chromosome 100 | 100
dendritic spine 99 | 99
ubiquitin ligase complex 99 | 99
peroxisome 98 | 98
nuclear matrix 97 | 97
PML body 94 | 94
Golgi lumen 93 | 93
keratin filament 93 | 93
trans-Golgi network membrane 92 | 92

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
D(2) dopamine receptor DRD2 Tclin GPCR -3.24474 1775.2 248
Neurofilament heavy polypeptide NEFH Tbio Non-IDG -2.73883 563.3 681
Host cell factor 1 HCFC1 Tbio Non-IDG -2.50024 341.6 160
Ras-related protein Rab-11A RAB11A Tbio Enzyme -2.60207 398.9 288
Stathmin-2 STMN2 Tbio Non-IDG -1.95188 90.0 305
Neuroguidin NGDN Tbio Non-IDG -2.18414 121.6 78
Homer protein homolog 1 HOMER1 Tbio Non-IDG -2.39539 267.3 178
Alpha-synuclein SNCA Tchem Non-IDG -3.59982 3997.3 1484
5-hydroxytryptamine receptor 3A HTR3A Tclin Ion Channel -3.37968 2392.4 232
Repressor of RNA polymerase III transcription MAF1 homolog MAF1 Tbio Enzyme -1.71328 60.5 107