Development Level

Tbio 165 | 11,178
Tchem 41 | 1,885
Tclin 32 | 612
Tdark 12 | 6,569

Collection

Ion Channel: IDG Consortium (T... 3 | 99
Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 16 | 979
abnormal behavior 11 | 298
preweaning lethality, incomple... 11 | 499
hyperactivity 6 | 148
abnormal bone structure 5 | 187
decreased bone mineral content 5 | 151
decreased startle reflex 4 | 75
decreased vertical activity 4 | 208
impaired glucose tolerance 4 | 75
small superior vagus ganglion 4 | 74
abnormal locomotor behavior 3 | 24
abnormal retina morphology 3 | 71
decreased grip strength 3 | 116
decreased heart weight 3 | 27
decreased mean corpuscular vol... 3 | 79
edema 3 | 59
hypoactivity 3 | 132
increased blood urea nitrogen ... 3 | 48
increased circulating choleste... 3 | 66
increased circulating sodium l... 3 | 71
increased circulating triglyce... 3 | 42
increased or absent threshold ... 3 | 101
increased total body fat amoun... 3 | 134
prenatal lethality prior to he... 3 | 87
abnormal cornea morphology 2 | 31
abnormal embryo size 2 | 220
abnormal gait 2 | 69
abnormal seminal vesicle morph... 2 | 114
decreased bone mineral density 2 | 126
decreased caudal vertebrae num... 2 | 53
decreased circulating alanine ... 2 | 47
decreased circulating aspartat... 2 | 34
decreased circulating phosphat... 2 | 27
decreased circulating serum al... 2 | 82
decreased heart left ventricle... 2 | 28
decreased lean body mass 2 | 135
decreased lymphocyte cell numb... 2 | 83
decreased neutrophil cell numb... 2 | 42
embryonic lethality prior to o... 2 | 239
enlarged heart 2 | 210
improved glucose tolerance 2 | 79
increased circulating HDL chol... 2 | 80
increased circulating alkaline... 2 | 122
increased heart weight 2 | 62
increased mean corpuscular vol... 2 | 92
increased neutrophil cell numb... 2 | 46
increased startle reflex 2 | 112
prenatal lethality 2 | 28
thin ventricular wall 2 | 24
abnormal embryo turning 1 | 31
abnormal hair growth 1 | 10
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal pancreas morphology 1 | 13
abnormal skin coloration 1 | 25
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
abnormal spleen morphology 1 | 55
abnormal vocalization 1 | 21
absent spleen 1 | 3
brachydactyly 1 | 19
cataract 1 | 92
decreased T cell number 1 | 15
decreased circulating bilirubi... 1 | 19
decreased circulating chloride... 1 | 30
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased hemoglobin content 1 | 68
decreased pulmonary respirator... 1 | 5
decreased red blood cell distr... 1 | 41
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
enlarged uterus 1 | 11
hemorrhage 1 | 23
hydrometra 1 | 53
impaired righting response 1 | 26
increased bone mineral content 1 | 108
increased cardiac muscle contr... 1 | 8
increased circulating alanine ... 1 | 13
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating potassiu... 1 | 29
increased circulating total pr... 1 | 28
increased fasted circulating g... 1 | 76
increased lean body mass 1 | 172
increased mean platelet volume 1 | 45
increased prepulse inhibition 1 | 32
increased vertical activity 1 | 24
limb grasping 1 | 41
microphthalmia 1 | 26
persistence of hyaloid vascula... 1 | 33
premature death 1 | 5
small kidney 1 | 16
small testis 1 | 58
syndactyly 1 | 23
thrombocytosis 1 | 27
tremors 1 | 39
trunk curl 1 | 16

Disease

Carcinoma 183 | 11,192
glioblastoma 137 | 5,635
medulloblastoma, large-cell 137 | 6,086
atypical teratoid / rhabdoid tumor 127 | 4,971
ependymoma 122 | 4,559
osteosarcoma 121 | 7,766
ovarian cancer 114 | 8,297
adult high grade glioma 112 | 3,701
group 3 medulloblastoma 97 | 4,002
Astrocytoma, Pilocytic 89 | 3,006
psoriasis 89 | 6,514
oligodendroglioma 84 | 2,768
lung cancer 82 | 4,607
astrocytic glioma 80 | 2,530
Kidney cancer 79 | 2,548
primitive neuroectodermal tumor 74 | 2,957
Breast cancer 68 | 3,469
Schizophrenia 65 | 1,136
lung carcinoma 65 | 2,755
Cancer 64 | 2,388
malignant mesothelioma 61 | 3,135
Pick disease 60 | 1,856
subependymal giant cell astrocytoma 47 | 2,230
intraductal papillary-mucinous adenoma (IPMA) 46 | 2,872
intraductal papillary-mucinous neoplasm (IPMN) 46 | 3,204
lung adenocarcinoma 45 | 2,627
Bipolar Disorder 44 | 646
pituitary cancer 44 | 1,915
invasive ductal carcinoma 43 | 2,867
non-small cell lung cancer 43 | 2,799
intraductal papillary-mucinous carcinoma (IPMC) 40 | 2,902
Depressive disorder 36 | 401
Alzheimer's disease 35 | 640
Neurodegenerative disease 35 | 402
cystic fibrosis 35 | 1,629
colon cancer 34 | 1,428
group 4 medulloblastoma 33 | 1,806
tuberculosis 33 | 1,963
Intellectual disability 32 | 998
interstitial cystitis 32 | 2,237
pancreatic cancer 31 | 2,322
Autosomal recessive predisposition 30 | 1,407
Epilepsy 30 | 775
Liver cancer 30 | 589
Parkinson's disease 30 | 378
ulcerative colitis 29 | 1,765
Alcoholic Intoxication, Chronic 28 | 283
Mental Depression 28 | 325
Cognitive delay 26 | 596
Global developmental delay 26 | 596
Mental and motor retardation 26 | 596
Amyotrophic lateral sclerosis 25 | 437
breast carcinoma 25 | 1,589
ductal carcinoma in situ 25 | 1,686
Major Depressive Disorder 23 | 293
Melanoma 23 | 689
Seizures 23 | 584
Autistic Disorder 22 | 358
adrenocortical carcinoma 22 | 1,385
Down syndrome 21 | 480
Mood Disorders 21 | 181
Skin cancer 21 | 451
cutaneous lupus erythematosus 21 | 1,016
diabetes mellitus 21 | 1,683
juvenile dermatomyositis 21 | 1,147
astrocytoma 20 | 1,113
Dull intelligence 19 | 634
Low intelligence 19 | 634
Mental Retardation 19 | 634
Mental deficiency 19 | 634
Poor school performance 19 | 634
active Crohn's disease 19 | 882
Multiple myeloma 18 | 1,296
Neuropathy 18 | 254
Obesity 18 | 655
Toxic encephalopathy 18 | 139
Unipolar Depression 18 | 244
Dementia 17 | 172
medulloblastoma 17 | 702
pancreatic ductal adenocarcinoma liver metastasis 17 | 1,911
Attention deficit hyperactivity disorder 16 | 272
Cocaine-Related Disorders 16 | 90
Multiple Sclerosis 16 | 527
Rheumatoid arthritis 16 | 1,156
aldosterone-producing adenoma 16 | 646
nasopharyngeal carcinoma 16 | 1,024
spina bifida 16 | 1,053
Muscle hypotonia 15 | 562
Waldenstrons macroglobulinemia 15 | 742
Atopic dermatitis 14 | 915
Nerve Degeneration 14 | 118
Prostatic Neoplasms 14 | 472
dermatomyositis 14 | 941
progressive supranuclear palsy 14 | 656
Alcohol dependence 13 | 107
Infantile onset 13 | 236
Osteoporosis 13 | 348
Vascular disease 13 | 294
active ulcerative colitis 13 | 736
pediatric high grade glioma 13 | 1,035

Tissue

Endocrine System 248 | 18,159
Female tissues 246 | 17,400
Digestive Tract 244 | 17,369
Male tissues 243 | 17,142
Nervous System 243 | 16,725
Skin and soft tissues 243 | 17,230
Urinary Tract 238 | 16,678
Liver and Pancreas 237 | 16,750
Respiratory system 234 | 16,393
Blood and immune system 233 | 16,909
Cardiovascular System 216 | 15,192

Target Family

Non-IDG 145 | 12,091
Enzyme 41 | 4,145
Kinase 20 | 634
Ion Channel 17 | 344
GPCR 14 | 408
Transporter 6 | 473
Transcription Factor 4 | 1,400
Epigenetic 3 | 242

GO Component

axon 250 | 250
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Potassium voltage-gated channel subfamily H member 1 KCNH1 Tclin Ion Channel -2.86111 714.2 150
Appetite-regulating hormone GHRL Tchem Non-IDG -3.63688 5052.5 631
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 HCN3 Tclin Ion Channel -1.65805 34.9 216
Potassium channel subfamily K member 2 KCNK2 Tclin Ion Channel -2.75349 578.2 86
Teneurin-3 TENM3 Tbio Non-IDG -2.01347 99.4 64
Potassium voltage-gated channel subfamily C member 3 KCNC3 Tclin Ion Channel -1.77541 61.9 232
Centriole, cilia and spindle-associated protein CCSAP Tbio Non-IDG -1.93256 89.5 55
Ras GTPase-activating-like protein IQGAP1 IQGAP1 Tbio Enzyme -2.27732 224.8 291
Lethal(2) giant larvae protein homolog 1 LLGL1 Tbio Non-IDG -3.09201 1212.4 143
Dual specificity mitogen-activated protein kinase kinase 4 MAP2K4 Tchem Kinase -2.43646 236.7 998