Development Level

Tbio 16 | 11,651
Tdark 2 | 6,593
Tchem 1 | 1,388

IMPC Phenotype

preweaning lethality, complete... 4 | 979
prenatal lethality 2 | 28
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
decreased circulating aspartat... 1 | 34
decreased circulating chloride... 1 | 30
decreased circulating creatini... 1 | 39
decreased coping response 1 | 8
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
impaired glucose tolerance 1 | 75
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased lymphocyte cell numb... 1 | 32
increased or absent threshold ... 1 | 101
pale yolk sac 1 | 25

Disease

Cancer 11 | 2,499
Carcinoma 10 | 11,493
ovarian cancer 10 | 8,520
psoriasis 10 | 6,694
ductal carcinoma in situ 9 | 1,745
interstitial cystitis 9 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
invasive ductal carcinoma 8 | 2,951
lung adenocarcinoma 8 | 2,716
atypical teratoid / rhabdoid tumor 7 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
non-small cell lung cancer 7 | 2,890
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
lung cancer 6 | 4,740
medulloblastoma, large-cell 6 | 6,241
osteosarcoma 6 | 7,950
cystic fibrosis 5 | 1,696
ependymoma 5 | 4,679
glioblastoma 5 | 5,792
malignant mesothelioma 5 | 3,232
Astrocytoma, Pilocytic 4 | 3,081
Breast cancer 4 | 3,578
Liver Cirrhosis, Experimental 4 | 769
Liver disease 4 | 237
breast carcinoma 4 | 1,638
diabetes mellitus 4 | 1,728
gastric carcinoma 4 | 807
group 3 medulloblastoma 4 | 4,104
nasopharyngeal carcinoma 4 | 1,058
primitive neuroectodermal tumor 4 | 3,035
Autosomal recessive predisposition 3 | 1,442
Breast Neoplasms 3 | 445
Cerebrovascular disease 3 | 238
Inflammatory bowel disease 3 | 151
Mammary Neoplasms 3 | 425
Prostatic Neoplasms 3 | 495
Stomach Neoplasms 3 | 300
acute myeloid leukemia 3 | 783
lung carcinoma 3 | 2,843
pancreatic cancer 3 | 2,398
pituitary cancer 3 | 1,972
Adenoma 2 | 167
Ameloblastoma 2 | 24
Brain Edema 2 | 50
Cell Transformation, Neoplastic 2 | 97
Cholestasis 2 | 155
Diabetic retinopathy 2 | 56
Diarrhea 2 | 253
Dilated cardiomyopathy 2 | 56
Hepatic veno-occlusive disease 2 | 16
Hypertension 2 | 396
Kidney cancer 2 | 2,613
Multiple Sclerosis 2 | 540
Neoplastic Cell Transformation 2 | 89
Onycholysis 2 | 6
Oxyphilic adenoma 2 | 22
Polycystic ovary syndrome 2 | 360
Pseudohypoaldosteronism 2 | 23
Renal Cell Carcinoma 2 | 214
Renal oncocytoma 2 | 22
Williams-Beuren syndrome 2 | 50
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
adult high grade glioma 2 | 3,801
aldosterone-producing adenoma 2 | 665
colon cancer 2 | 1,478
fibroadenoma 2 | 559
pediatric high grade glioma 2 | 1,064
primary Sjogren syndrome 2 | 735
urothelial carcinoma 2 | 318
ANONYCHIA 1 | 20
Acute Promyelocytic Leukemia 1 | 40
Adenocarcinoma 1 | 122
Carcinoma, Renal Cell 1 | 124
Chloracne 1 | 32
Communicating Hydrocephalus 1 | 8
Epithelial ovarian cancer 1 | 9
Fragile skin 1 | 18
Irritable bowel syndrome 1 | 60
Keloid 1 | 37
Leukemia, Promyelocytic, Acute 1 | 36
Microphthalmia 1 | 76
Non-immune hydrops fetalis 1 | 11
Oral mucosal blistering 1 | 10
Ovarian epithelial cancer 1 | 10
Ovarian hyperstimulation syndrome 1 | 19
Palmoplantar keratosis 1 | 74
Precancerous Conditions 1 | 80
Pulmonary Disease, Chronic Obstructive 1 | 31
Purpura fulminans 1 | 9
Respiratory Distress Syndrome, Adult 1 | 40
Skin Erosion 1 | 12
Skin disease 1 | 66
Sparse eyebrow 1 | 42
Sparse scalp hair 1 | 42
Stevens-Johnson syndrome 1 | 92
Stomach cancer 1 | 30
Syncope 1 | 22
VACTERL association 1 | 26
chronic kidney disease 1 | 90

Tissue

Endocrine System 18 | 18,159
Blood and immune system 17 | 16,909
Digestive Tract 17 | 17,369
Female tissues 17 | 17,400
Liver and Pancreas 17 | 16,750
Male tissues 17 | 17,142
Nervous System 17 | 16,725
Respiratory system 17 | 16,393
Skin and soft tissues 16 | 17,230
Urinary Tract 16 | 16,678
Cardiovascular System 15 | 15,192

Target Family

Non-IDG 17 | 12,091
Enzyme 1 | 4,145
GPCR 1 | 408

GO Component

apicolateral plasma membrane 19 | 19
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Claudin-8 CLDN8 Tbio Non-IDG -1.50382 29.7 184
Claudin-6 CLDN6 Tbio Non-IDG -1.76879 66.0 370
Junction plakoglobin JUP Tbio Non-IDG -2.01808 101.8 719
Claudin-3 CLDN3 Tbio Non-IDG -2.37681 227.3 358
Multiple PDZ domain protein MPDZ Tbio Non-IDG -1.63690 47.3 58
Epiplakin EPPK1 Tdark Non-IDG -1.29990 21.1 0
Thrombomodulin THBD Tbio Non-IDG -3.31892 1993.7 492
Claudin-4 CLDN4 Tbio Non-IDG -2.57691 369.5 428
Keratin, type II cytoskeletal 8 KRT8 Tbio Non-IDG -2.87670 710.7 1827
Microtubule cross-linking factor 1 MTCL1 Tbio Non-IDG -0.63960 4.60 21