Development Level

Tbio 188 | 11,445
Tchem 54 | 1,598
Tclin 35 | 613
Tdark 15 | 6,588

Collection

Ion Channel: IDG Consortium (T... 3 | 99
GPCR: IDG Consortium (Targets) 2 | 126
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 20 | 979
decreased total body fat amoun... 8 | 207
abnormal retina morphology 7 | 71
abnormal bone structure 6 | 187
decreased grip strength 6 | 116
embryonic lethality prior to o... 6 | 239
increased lean body mass 6 | 172
preweaning lethality, incomple... 6 | 499
abnormal behavior 5 | 298
abnormal seminal vesicle morph... 5 | 114
decreased body weight 5 | 161
embryonic lethality prior to t... 5 | 278
increased blood urea nitrogen ... 5 | 48
abnormal vibrissa morphology 4 | 25
decreased bone mineral content 4 | 151
decreased startle reflex 4 | 75
enlarged heart 4 | 210
hypoactivity 4 | 132
increased or absent threshold ... 4 | 101
increased startle reflex 4 | 112
abnormal embryo size 3 | 220
abnormal kidney morphology 3 | 65
abnormal lens morphology 3 | 81
abnormal pelvic girdle bone mo... 3 | 12
abnormal sleep behavior 3 | 70
decreased circulating choleste... 3 | 93
decreased circulating glucose ... 3 | 126
decreased circulating triglyce... 3 | 79
decreased leukocyte cell numbe... 3 | 73
decreased vertical activity 3 | 208
impaired glucose tolerance 3 | 75
increased anti-nuclear antigen... 3 | 19
increased circulating HDL chol... 3 | 80
increased circulating alkaline... 3 | 122
increased circulating iron lev... 3 | 30
increased heart weight 3 | 62
abnormal coat appearance 2 | 31
abnormal eye morphology 2 | 68
abnormal forebrain development 2 | 20
abnormal heart morphology 2 | 162
abnormal hindbrain development 2 | 16
abnormal midbrain development 2 | 20
abnormal neural tube closure 2 | 46
abnormal pericardium morpholog... 2 | 26
absent vibrissae 2 | 12
cataract 2 | 92
decreased body length 2 | 101
decreased circulating HDL chol... 2 | 68
decreased circulating amylase ... 2 | 28
decreased circulating insulin ... 2 | 76
decreased eosinophil cell numb... 2 | 24
decreased erythrocyte cell num... 2 | 62
decreased hemoglobin content 2 | 68
decreased mean corpuscular hem... 2 | 50
decreased mean corpuscular vol... 2 | 79
decreased prepulse inhibition 2 | 82
embryonic growth retardation 2 | 106
impaired righting response 2 | 26
improved glucose tolerance 2 | 79
increased bone mineral content 2 | 108
increased circulating calcium ... 2 | 34
increased circulating sodium l... 2 | 71
increased grip strength 2 | 41
increased mean corpuscular vol... 2 | 92
increased total body fat amoun... 2 | 134
persistence of hyaloid vascula... 2 | 33
short tibia 2 | 97
stereotypic behavior 2 | 3
trunk curl 2 | 16
abnormal cornea morphology 1 | 31
abnormal ear morphology 1 | 9
abnormal embryo turning 1 | 31
abnormal epididymis morphology 1 | 42
abnormal locomotor activation 1 | 16
abnormal neural tube morpholog... 1 | 12
abnormal retinal vasculature m... 1 | 27
abnormal tail movements 1 | 12
abnormal vertebrae morphology 1 | 18
abnormal whole-body plethysmog... 1 | 4
absent pinna reflex 1 | 23
decreased blood urea nitrogen ... 1 | 51
decreased circulating calcium ... 1 | 36
decreased circulating chloride... 1 | 30
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
dilated heart left ventricle 1 | 11
enlarged uterus 1 | 11
increased body weight 1 | 25
increased circulating alanine ... 1 | 13
increased circulating amylase ... 1 | 25
increased circulating aspartat... 1 | 15
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating potassiu... 1 | 29
increased fasted circulating g... 1 | 76
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
prenatal lethality 1 | 28
small superior vagus ganglion 1 | 74

Disease

Carcinoma 223 | 11,493
ovarian cancer 145 | 8,520
psoriasis 134 | 6,694
osteosarcoma 129 | 7,950
medulloblastoma, large-cell 109 | 6,241
glioblastoma 107 | 5,792
lung cancer 105 | 4,740
ependymoma 102 | 4,679
Breast cancer 88 | 3,578
atypical teratoid / rhabdoid tumor 86 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 82 | 3,291
lung adenocarcinoma 82 | 2,716
malignant mesothelioma 81 | 3,232
intraductal papillary-mucinous adenoma (IPMA) 80 | 2,955
non-small cell lung cancer 80 | 2,890
invasive ductal carcinoma 76 | 2,951
pancreatic cancer 75 | 2,398
Cancer 74 | 2,499
adult high grade glioma 72 | 3,801
interstitial cystitis 72 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 72 | 2,989
Autosomal recessive predisposition 70 | 1,442
Kidney cancer 70 | 2,613
Astrocytoma, Pilocytic 69 | 3,081
lung carcinoma 66 | 2,843
group 3 medulloblastoma 65 | 4,104
ductal carcinoma in situ 57 | 1,745
pituitary cancer 57 | 1,972
oligodendroglioma 56 | 2,850
cystic fibrosis 54 | 1,696
subependymal giant cell astrocytoma 49 | 2,287
ulcerative colitis 48 | 1,819
astrocytic glioma 46 | 2,597
primitive neuroectodermal tumor 45 | 3,035
colon cancer 41 | 1,478
pancreatic ductal adenocarcinoma liver metastasis 41 | 1,962
Kidney disease 40 | 430
breast carcinoma 40 | 1,638
tuberculosis 39 | 2,010
diabetes mellitus 38 | 1,728
Hypertension 36 | 396
spina bifida 36 | 1,074
Schizophrenia 32 | 1,160
esophageal adenocarcinoma 32 | 737
nasopharyngeal carcinoma 32 | 1,058
Pick disease 30 | 1,894
adrenocortical carcinoma 30 | 1,428
active ulcerative colitis 28 | 764
Melanoma 27 | 711
active Crohn's disease 27 | 922
nephrosclerosis 27 | 333
Rheumatoid arthritis 26 | 1,191
primary pancreatic ductal adenocarcinoma 26 | 1,109
Breast Neoplasms 25 | 445
Diarrhea 25 | 253
Epilepsy 25 | 792
Skin cancer 25 | 469
cutaneous lupus erythematosus 25 | 1,057
group 4 medulloblastoma 25 | 1,855
Mammary Neoplasms 24 | 425
Intellectual disability 23 | 1,016
Prostatic Neoplasms 23 | 495
gastric carcinoma 23 | 807
Liver Cirrhosis, Experimental 21 | 769
Bipolar Disorder 20 | 666
Failure to gain weight 20 | 365
Hypertensive disease 20 | 292
Pediatric failure to thrive 20 | 365
juvenile dermatomyositis 20 | 1,187
pediatric high grade glioma 20 | 1,064
Dull intelligence 19 | 645
Low intelligence 19 | 645
Mental Retardation 19 | 645
Mental deficiency 19 | 645
Obesity 19 | 678
Poor school performance 19 | 645
acute quadriplegic myopathy 19 | 1,158
astrocytoma 19 | 1,146
fibroadenoma 19 | 559
Endometriosis 18 | 540
Liver cancer 18 | 604
Metabolic acidosis 18 | 90
Osteoporosis 17 | 363
Seizures 17 | 596
chronic rhinosinusitis 17 | 512
dermatomyositis 17 | 966
urothelial carcinoma 17 | 318
Down syndrome 16 | 499
Nonsyndromic deafness 16 | 142
Anemia 15 | 365
Atherosclerosis 15 | 291
Atopic dermatitis 15 | 952
Cataract 15 | 297
Coronary artery disease 15 | 268
Multiple myeloma 15 | 1,332
Short stature 15 | 531
aldosterone-producing adenoma 15 | 665
non primary Sjogren syndrome sicca 15 | 891
acute myeloid leukemia 14 | 783
progressive supranuclear palsy 14 | 676

Tissue

Endocrine System 284 | 18,159
Digestive Tract 279 | 17,369
Male tissues 273 | 17,142
Urinary Tract 272 | 16,678
Liver and Pancreas 271 | 16,750
Female tissues 270 | 17,400
Skin and soft tissues 270 | 17,230
Nervous System 265 | 16,725
Blood and immune system 260 | 16,909
Respiratory system 254 | 16,393
Cardiovascular System 220 | 15,192

Target Family

Non-IDG 137 | 12,091
Transporter 65 | 473
Enzyme 38 | 4,145
Ion Channel 21 | 344
Kinase 19 | 634
GPCR 12 | 408

GO Component

apical plasma membrane 292 | 292
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein Shroom2 SHROOM2 Tbio Non-IDG -1.07032 11.9 112
Annexin A13 ANXA13 Tbio Non-IDG -1.19458 15.6 162
Sodium bicarbonate cotransporter 3 SLC4A7 Tbio Transporter -1.82039 64.7 133
Large neutral amino acids transporter small subunit 1 SLC7A5 Tbio Transporter -1.90516 156.1 254
Solute carrier family 12 member 1 SLC12A1 Tclin Transporter -2.37125 226.3 178
Moesin MSN Tbio Non-IDG -2.61389 361.7 550
Sodium-dependent phosphate transport protein 1 SLC17A1 Tbio Transporter -1.73498 53.1 39
Aquaporin-1 AQP1 Tbio Non-IDG -3.08125 1107.4 374
Folate receptor alpha FOLR1 Tchem Non-IDG -2.33242 206.1 303
Adherens junction-associated protein 1 AJAP1 Tbio Non-IDG -1.20907 21.2 25