Development Level

Tbio 16 | 11,445
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal embryo size 3 | 220
embryonic growth retardation 3 | 106
anophthalmia 2 | 33
embryonic lethality prior to o... 2 | 239
abnormal craniofacial morpholo... 1 | 33
abnormal forebrain morphology 1 | 10
abnormal head shape 1 | 10
abnormal heart morphology 1 | 162
abnormal hindbrain morphology 1 | 10
abnormal joint morphology 1 | 23
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal placenta morphology 1 | 5
abnormal placenta size 1 | 20
abnormal skin coloration 1 | 25
brachydactyly 1 | 19
decreased body weight 1 | 161
decreased caudal vertebrae num... 1 | 53
decreased circulating alanine ... 1 | 47
edema 1 | 59
embryonic lethality prior to t... 1 | 278
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased mean corpuscular vol... 1 | 92
microphthalmia 1 | 26
pallor 1 | 34
prenatal lethality 1 | 28
syndactyly 1 | 23

Disease

ovarian cancer 10 | 8,520
Carcinoma 9 | 11,493
osteosarcoma 8 | 7,950
psoriasis 7 | 6,694
glioblastoma 6 | 5,792
atypical teratoid / rhabdoid tumor 5 | 5,112
ependymoma 5 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
medulloblastoma, large-cell 5 | 6,241
Breast cancer 4 | 3,578
adrenocortical carcinoma 4 | 1,428
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
lung cancer 4 | 4,740
Cancer 3 | 2,499
Kidney cancer 3 | 2,613
Pick disease 3 | 1,894
diabetes mellitus 3 | 1,728
group 3 medulloblastoma 3 | 4,104
invasive ductal carcinoma 3 | 2,951
lung adenocarcinoma 3 | 2,716
malignant mesothelioma 3 | 3,232
non primary Sjogren syndrome sicca 3 | 891
non-small cell lung cancer 3 | 2,890
Anteverted nostril 2 | 191
Atopic dermatitis 2 | 952
Autosomal recessive predisposition 2 | 1,442
Concave bridge of nose 2 | 195
Decreased projection of midface 2 | 105
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Endometriosis 2 | 540
Fetal Growth Retardation 2 | 189
Hypotrophic malar bone 2 | 129
Hypotrophic midface 2 | 105
Infant, Small for Gestational Age 2 | 176
Intellectual disability 2 | 1,016
Intrauterine retardation 2 | 176
Long philtrum 2 | 137
Low Birth Weights 2 | 69
Malar flattening 2 | 129
Midface retrusion 2 | 105
Penile hypospadias 2 | 106
Postnatal growth retardation 2 | 57
Renal Cell Carcinoma 2 | 214
Short neck 2 | 140
Short stature 2 | 531
Small for gestational age (disorder) 2 | 69
Small midface 2 | 105
Triangular face 2 | 58
adult high grade glioma 2 | 3,801
astrocytic glioma 2 | 2,597
breast carcinoma 2 | 1,638
ductal carcinoma in situ 2 | 1,745
oligodendroglioma 2 | 2,850
pancreatic cancer 2 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
primitive neuroectodermal tumor 2 | 3,035
3-M syndrome 1 | 15
Abnormality of the metaphyses 1 | 48
Abnormality of vision 1 | 40
Angelman syndrome 1 | 34
Ascites 1 | 22
Breast Neoplasms 1 | 445
Carcinoma of colon 1 | 32
Carcinoma, Renal Cell 1 | 124
Cardiac arrest 1 | 36
Class III malocclusion 1 | 78
Cystic kidney 1 | 30
DOID:9917 1 | 31
Epilepsies, Myoclonic 1 | 32
Esophageal Squamous Cell Carcinoma 1 | 77
Generalized myoclonic seizures 1 | 30
Growth Disorders 1 | 35
Hypertrophy of lower jaw 1 | 78
Increased nuchal translucency 1 | 6
Increased size of mandible 1 | 78
Late tooth eruption 1 | 61
Lordosis 1 | 54
MOSAIC VARIEGATED ANEUPLOIDY SYNDROME 1 | 5
Mammary Neoplasms 1 | 425
Mandibular hyperplasia 1 | 78
Mitral valve stenosis 1 | 14
Myoclonic Epilepsies, Progressive 1 | 44
Neoplasms, Germ Cell and Embryonal 1 | 15
Nephroblastoma 1 | 51
Neuronal ceroid lipofuscinosis 2 1 | 17
Pointed chin 1 | 33
Renal cyst 1 | 30
Rhabdomyosarcoma 1 | 39
Short ribs 1 | 30
Short thorax 1 | 21
Silver-Russell syndrome 1 | 39
Small testicle 1 | 75
Spina bifida occulta 1 | 19
Squamous cell carcinoma of esophagus 1 | 77
Varicocele 1 | 26
interstitial lung disease 1 | 298
mandibular excess (physical finding) 1 | 78
mosaic variegated aneuploidy syndrome 1 1 | 4
non-small cell lung carcinoma 1 | 317

Tissue

Blood and immune system 18 | 16,909
Cardiovascular System 18 | 15,192
Digestive Tract 18 | 17,369
Endocrine System 18 | 18,159
Female tissues 18 | 17,400
Liver and Pancreas 18 | 16,750
Male tissues 18 | 17,142
Nervous System 18 | 16,725
Respiratory system 18 | 16,393
Skin and soft tissues 18 | 17,230
Urinary Tract 18 | 16,678

Target Family

Enzyme 11 | 4,145
Non-IDG 6 | 12,091
Kinase 1 | 634

GO Component

anaphase-promoting complex 18 | 18
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Anaphase-promoting complex subunit 10 ANAPC10 Tbio Enzyme -1.23751 18.1 156
Anaphase-promoting complex subunit 11 ANAPC11 Tbio Enzyme -1.27406 17.9 239
Anaphase-promoting complex subunit 2 ANAPC2 Tbio Enzyme -0.45557 2.44 166
Anaphase-promoting complex subunit 4 ANAPC4 Tbio Enzyme 0.43 0.13 156
Anaphase-promoting complex subunit 7 ANAPC7 Tbio Enzyme -0.17118 1.40 73
Cell division cycle protein 23 homolog CDC23 Tbio Non-IDG -1.50528 30.4 191
Cullin-7 CUL7 Tbio Non-IDG -1.49747 38.0 139
Anaphase-promoting complex subunit 15 ANAPC15 Tdark Enzyme -0.41378 2.22 27
Ubiquitin-conjugating enzyme E2 C UBE2C Tbio Non-IDG -1.93680 92.1 352
Ubiquitin-conjugating enzyme E2 S UBE2S Tbio Non-IDG -2.36597 158.3 384