Development Level

Tbio 24 | 11,445
Tdark 7 | 6,588
Tchem 6 | 1,598
Tclin 2 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

decreased leukocyte cell numbe... 2 | 73
decreased mean corpuscular hem... 2 | 50
decreased vertical activity 2 | 208
male infertility 2 | 123
abnormal behavior 1 | 298
abnormal limb morphology 1 | 13
abnormal tail morphology 1 | 25
abnormal testis morphology 1 | 43
cyanosis 1 | 7
decreased basophil cell number 1 | 16
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating glucose ... 1 | 126
decreased heart left ventricle... 1 | 28
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased mean platelet volume 1 | 25
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased threshold for audito... 1 | 26
decreased total body fat amoun... 1 | 207
edema 1 | 59
female infertility 1 | 60
hemorrhage 1 | 23
improved glucose tolerance 1 | 79
increased body length 1 | 32
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased exploration in new e... 1 | 8
increased mean corpuscular hem... 1 | 96
increased total body fat amoun... 1 | 134
preweaning lethality, complete... 1 | 979
respiratory system phenotype 1 | 2
small testis 1 | 58
thin ventricular wall 1 | 24

Disease

Carcinoma 27 | 11,493
osteosarcoma 22 | 7,950
ovarian cancer 20 | 8,520
lung cancer 17 | 4,740
medulloblastoma, large-cell 16 | 6,241
Cancer 12 | 2,499
atypical teratoid / rhabdoid tumor 11 | 5,112
ependymoma 11 | 4,679
glioblastoma 11 | 5,792
group 3 medulloblastoma 11 | 4,104
malignant mesothelioma 11 | 3,232
Kidney cancer 10 | 2,613
adult high grade glioma 10 | 3,801
psoriasis 10 | 6,694
non-small cell lung cancer 8 | 2,890
oligodendroglioma 8 | 2,850
Breast cancer 7 | 3,578
astrocytic glioma 7 | 2,597
invasive ductal carcinoma 7 | 2,951
primitive neuroectodermal tumor 7 | 3,035
tuberculosis 7 | 2,010
Neurodegenerative disease 6 | 414
interstitial cystitis 6 | 2,312
lung carcinoma 6 | 2,843
pituitary cancer 6 | 1,972
Astrocytoma, Pilocytic 5 | 3,081
Waldenstrons macroglobulinemia 5 | 765
dermatomyositis 5 | 966
group 4 medulloblastoma 5 | 1,855
lung adenocarcinoma 5 | 2,716
subependymal giant cell astrocytoma 5 | 2,287
Dysarthria 4 | 192
Multiple myeloma 4 | 1,332
Pick disease 4 | 1,894
acute quadriplegic myopathy 4 | 1,158
colon cancer 4 | 1,478
diabetes mellitus 4 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
pancreatic cancer 4 | 2,398
ulcerative colitis 4 | 1,819
Adult onset 3 | 82
Alzheimer's disease 3 | 658
Amyotrophic lateral sclerosis 3 | 451
Cardiomyopathy 3 | 116
Depressive disorder 3 | 409
Dyslexia 3 | 43
Dystonia 3 | 164
Nerve Degeneration 3 | 121
Rheumatoid arthritis 3 | 1,191
Schizophrenia 3 | 1,160
Toxic encephalopathy 3 | 141
breast carcinoma 3 | 1,638
Acquired metabolic disease 2 | 336
Aggressive behavior 2 | 75
Aggressive reaction 2 | 75
Anxiety 2 | 136
Anxiety disease 2 | 113
Arsenic Poisoning 2 | 62
Autosomal dominant cerebellar ataxia 2 | 33
Big calvaria 2 | 147
Breast Neoplasms 2 | 445
Cerebral atrophy 2 | 178
Congestive heart failure 2 | 113
Cortical white matter abnormalities seen on MRI 2 | 18
Dementia 2 | 175
Dystonic disease 2 | 106
Frontal bossing 2 | 157
Frontotemporal dementia 2 | 51
Heart failure 2 | 162
Hepatomegaly 2 | 285
Hermansky-Pudlak syndrome 2 | 42
Highly variable clinical phenotype 2 | 150
Highly variable phenotype and severity 2 | 150
Highly variable phenotype, even within families 2 | 150
Huntington's disease 2 | 76
Hyperreflexia 2 | 209
Increased head circumference 2 | 147
Increased size of cranium 2 | 147
Increased size of skull 2 | 147
Leukoaraiosis 2 | 18
Liver Cirrhosis, Experimental 2 | 769
Loss of speech 2 | 16
Lung Neoplasms 2 | 232
Mammary Neoplasms 2 | 425
Melanoma 2 | 711
Neoplasm Invasiveness 2 | 161
Personality change 2 | 23
Phenotypic variability 2 | 150
Physical aggression 2 | 76
Stereotyped Behavior 2 | 37
Stereotypic Movement Disorder 2 | 42
Tooth Crowding 2 | 45
Tooth mass arch size discrepancy 2 | 45
Tooth size discrepancy 2 | 45
active ulcerative colitis 2 | 764
cystic fibrosis 2 | 1,696
medulloblastoma 2 | 720
pancreatic carcinoma 2 | 562
posterior fossa group A ependymoma 2 | 468
progressive supranuclear palsy 2 | 676

Tissue

Endocrine System 39 | 18,159
Female tissues 39 | 17,400
Blood and immune system 38 | 16,909
Digestive Tract 38 | 17,369
Liver and Pancreas 38 | 16,750
Male tissues 38 | 17,142
Skin and soft tissues 38 | 17,230
Urinary Tract 38 | 16,678
Cardiovascular System 37 | 15,192
Respiratory system 37 | 16,393
Nervous System 36 | 16,725

Target Family

Non-IDG 21 | 12,091
Enzyme 7 | 4,145
Transcription Factor 4 | 1,400
Epigenetic 3 | 242
Kinase 3 | 634
TF/Epigenetic 1 | 38

GO Component

aggresome 39 | 39
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nesprin-2 SYNE2 Tbio Non-IDG -2.62747 380.6 39
Unique cartilage matrix-associated protein UCMA Tbio Non-IDG -0.90625 8.26 59
Heat shock 70 kDa protein 1A HSPA1B Tchem Non-IDG -3.10995 0.00000 1174
Heat shock 70 kDa protein 1B HSPA1B Tbio Non-IDG -1.61862 0.00000 60
Tripartite motif-containing protein 66 TRIM66 Tdark Epigenetic -0.11394 2.15 17
E3 ubiquitin-protein ligase TRIM37 TRIM37 Tbio Enzyme -3.25892 1754.8 177
RING finger protein 32 RNF32 Tdark Non-IDG -0.50515 2.10 62
5'-3' exoribonuclease 2 XRN2 Tbio Enzyme -1.52792 31.8 121
Zinc finger and BTB domain-containing protein 14 ZBTB14 Tbio Transcription Factor -1.36289 24.1 47
Elongation factor 2 EEF2 Tchem Non-IDG -2.95619 938.4 363