Development Level

Tbio 4 | 11,651

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal coat appearance 1 | 31

Disease

Carcinoma 4 | 11,493
Kidney cancer 3 | 2,613
ovarian cancer 3 | 8,520
Breast cancer 2 | 3,578
Chronic kidney disease stage 5 2 | 31
Focal glomerulosclerosis 2 | 37
Glomerulosclerosis, Focal Segmental 2 | 28
MYH-9 related disease 2 | 12
Proteinuria 2 | 144
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
osteosarcoma 2 | 7,950
psoriasis 2 | 6,694
Abnormal thrombosis 1 | 6
Abnormality of the urinary system 1 | 21
Alport syndrome 1 | 21
Atopic dermatitis 1 | 952
Autoimmune thrombocytopenic purpura 1 | 13
Bernard-Soulier syndrome 1 | 14
Bleeding time prolonged 1 | 31
Breast Neoplasms 1 | 445
Byzanthine arch palate 1 | 194
Carcinoma, Lobular 1 | 6
Cerebral cavernous malformation 3 1 | 4
Congenital Bilateral Cataracts 1 | 50
Congenital cataract 1 | 50
Congenital joint contractures 1 | 9
DEAFNESS, AUTOSOMAL DOMINANT 17 1 | 1
Decreased platelet count 1 | 111
Diabetes Mellitus, Non-Insulin-Dependent 1 | 145
Diabetes Mellitus, Type 2 1 | 142
Disorder of eye 1 | 27
Distal arthrogryposis 1 | 42
Ecchymosis 1 | 66
Endometrial cancer 1 | 311
Epistaxis 1 | 43
Epstein syndrome (disorder) 1 | 1
Eye Abnormalities 1 | 35
Eye and adnexa disease 1 | 18
Fechtner syndrome (disorder) 1 | 1
Gastrointestinal Hemorrhage 1 | 52
Generalized muscle weakness 1 | 57
Giant platelet (morphologic abnormality) 1 | 5
Hearing Loss, High-Frequency 1 | 4
Hearing loss, progressive sensorineural 1 | 23
Hematuria 1 | 36
Hereditary nephritis 1 | 2
High-frequency sensorineural hearing impairment 1 | 2
Highly variable severity 1 | 157
Hypertension, Renal 1 | 3
INCLUSION BODY MYOPATHY 3, AUTOSOMAL DOMINANT 1 | 1
Inclusion body myopathy 3 1 | 1
Increased susceptibility to schizophrenia 1 | 2
Increased tendency to bruise 1 | 66
Kidney Failure, Chronic 1 | 46
Kidney disease 1 | 430
Large intestine cancer 1 | 126
Liver cancer 1 | 604
MACROTHROMBOCYTOPENIA AND PROGRESSIVE SENSORINEURAL DEAFNESS 1 | 1
Macrothrombocytopenia 1 | 4
May-Hegglin anomaly 1 | 1
Melanoma 1 | 711
Menorrhagia 1 | 25
Microscopic hematuria 1 | 9
Muscle fiber inclusion bodies 1 | 4
Myocardial Infarction 1 | 151
Myopathic facies 1 | 13
Myopathy 1 | 185
Neck muscle weakness 1 | 17
Neoplasm Invasiveness 1 | 161
Nephritis 1 | 51
Nephritis, Hereditary 1 | 2
Nephrotic Syndrome 1 | 78
Nonsyndromic deafness 1 | 142
Ophthalmoplegia 1 | 106
Patent foramen ovale 1 | 10
Polycystic ovary syndrome 1 | 360
Proximal muscle weakness 1 | 47
Proximal neurogenic muscle weakness 1 | 47
Pseudosarcomatous fibromatosis 1 | 8
Renal hypertension 1 | 3
SEBASTIAN SYNDROME 1 | 1
Senile cataract 1 | 4
Sensorineural hearing loss 1 | 106
Skin cancer 1 | 469
Sulfhemoglobinemia 1 | 3
Syphilis 1 | 17
Thrombocytopenia 1 | 197
Type 2 diabetes mellitus 1 | 272
Variable expressivity 1 | 157
Yaws 1 | 7
active Crohn's disease 1 | 922
acute quadriplegic myopathy 1 | 1,158
adrenocortical carcinoma 1 | 1,428
breast carcinoma 1 | 1,638
chronic rhinosinusitis 1 | 512
cystic fibrosis and chronic rhinosinusitis 1 | 214
end stage renal failure 1 | 8
nasopharyngeal carcinoma 1 | 1,058
progressive supranuclear palsy 1 | 676

Tissue

Blood and immune system 4 | 16,909
Cardiovascular System 4 | 15,192
Digestive Tract 4 | 17,369
Endocrine System 4 | 18,159
Male tissues 4 | 17,142
Nervous System 4 | 16,725
Respiratory system 4 | 16,393
Skin and soft tissues 4 | 17,230
Urinary Tract 4 | 16,678
Female tissues 3 | 17,400
Liver and Pancreas 3 | 16,750

Target Family

Non-IDG 4 | 12,091

GO Component

actomyosin contractile ring 4 | 4
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myosin-2 MYH2 Tbio Non-IDG -2.14128 114.9 63
Myosin-9 MYH9 Tbio Non-IDG -3.01272 1033.4 349
Anillin ANLN Tbio Non-IDG -2.40271 193.5 150
Macrophage erythroblast attacher MAEA Tbio Non-IDG -2.88589 801.6 197