Development Level

Tbio 8 | 10,625
Tchem 2 | 1,890
Tclin 1 | 602
Tdark 1 | 7,003

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 3 | 633
abnormal embryo size 2 | 112
abnormal placenta size 2 | 10
embryonic lethality prior to t... 2 | 187
prenatal lethality prior to he... 2 | 64
abnormal behavior 1 | 226
abnormal bone structure 1 | 131
abnormal coat/hair pigmentatio... 1 | 54
abnormal limb bud morphology 1 | 15
abnormal skin coloration 1 | 18
abnormal sleep behavior 1 | 63
abnormal vertebrae morphology 1 | 14
absent heartbeat 1 | 6
anophthalmia 1 | 20
decreased Ly6C low monocyte nu... 1 | 23
decreased body weight 1 | 174
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating alanine ... 1 | 53
decreased circulating aspartat... 1 | 27
decreased circulating calcium ... 1 | 33
decreased circulating choleste... 1 | 85
decreased circulating fructosa... 1 | 31
decreased circulating serum al... 1 | 79
decreased circulating total pr... 1 | 41
decreased fasted circulating g... 1 | 49
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular vol... 1 | 50
decreased mean platelet volume 1 | 12
decreased rib number 1 | 59
decreased total body fat amoun... 1 | 186
decreased total retina thickne... 1 | 20
edema 1 | 11
enlarged heart 1 | 111
hemorrhage 1 | 12
hyperactivity 1 | 108
improved glucose tolerance 1 | 56
increased circulating alkaline... 1 | 119
increased circulating chloride... 1 | 43
increased circulating creatini... 1 | 29
increased circulating phosphat... 1 | 24
increased effector memory CD4-... 1 | 15
increased heart weight 1 | 37
increased lean body mass 1 | 107
increased or absent threshold ... 1 | 128
increased plasma cell number 1 | 5
increased red blood cell distr... 1 | 21
pale liver 1 | 5
pale yolk sac 1 | 12
pallor 1 | 13
preweaning lethality, incomple... 1 | 260

Disease

osteosarcoma 10 | 7,933
ovarian cancer 8 | 8,484
Carcinoma 7 | 2,147
medulloblastoma, large-cell 7 | 6,234
psoriasis 7 | 6,685
glioblastoma 6 | 5,572
adult high grade glioma 5 | 2,148
atypical teratoid / rhabdoid tumor 5 | 4,369
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,956
lung adenocarcinoma 4 | 2,713
lung cancer 4 | 4,466
malignant mesothelioma 4 | 3,162
pilocytic astrocytoma 4 | 3,086
Breast cancer 3 | 3,094
acute myeloid leukemia 3 | 780
group 3 medulloblastoma 3 | 2,254
interstitial cystitis 3 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,289
invasive ductal carcinoma 3 | 2,950
lung carcinoma 3 | 2,844
oligodendroglioma 3 | 2,849
primitive neuroectodermal tumor 3 | 3,031
Cancer 2 | 2,346
Down syndrome 2 | 548
Focal glomerulosclerosis 2 | 22
Nonsyndromic deafness 2 | 121
Sensorineural hearing loss 2 | 107
astrocytic glioma 2 | 2,241
astrocytoma 2 | 1,493
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
cystic fibrosis 2 | 1,665
diabetes mellitus 2 | 1,663
ependymoma 2 | 2,514
gastric carcinoma 2 | 832
group 4 medulloblastoma 2 | 1,875
juvenile dermatomyositis 2 | 1,189
medulloblastoma 2 | 1,524
mucosa-associated lymphoid tissue lymphoma 2 | 480
pancreatic cancer 2 | 2,300
posterior fossa group A ependymoma 2 | 1,511
subependymal giant cell astrocytoma 2 | 2,287
ulcerative colitis 2 | 2,087
Alport syndrome 1 | 21
Alzheimer's disease 1 | 644
Amyotrophic Lateral Sclerosis 1 | 431
Anemia 1 | 252
Autistic Disorder 1 | 320
Autoimmune thrombocytopenic purpura 1 | 14
Bernard-Soulier syndrome 1 | 14
Bladder Neoplasm 1 | 109
Brachydactyly 1 | 52
Cataract 1 | 104
Chediak-Higashi syndrome 1 | 24
Chromosome 2q37 deletion syndrome 1 | 4
Cocaine-Related Disorders 1 | 88
Colitis 1 | 46
Contact Dermatitis 1 | 80
Diarrhea 1 | 155
Duchenne muscular dystrophy 1 | 602
GRISCELLI SYNDROME, TYPE 3 1 | 2
Gastroenteritis 1 | 46
Gaucher disease type 1 1 | 171
Hermansky-Pudlak syndrome 1 | 43
Hodgkin's lymphoma, nodular sclerosis 1 | 24
IGA Glomerulonephritis 1 | 454
Infantile myofibromatosis 1 | 13
Kidney Failure, Chronic 1 | 45
Kidney disease 1 | 396
Kidney failure 1 | 39
Multiple Sclerosis 1 | 498
Neuropathy 1 | 210
Parkinson's disease 1 | 364
Peripheral Neuropathy 1 | 303
Peripheral T-cell lymphoma 1 | 24
Pick disease 1 | 1,893
Primary cutaneous T-cell lymphoma 1 | 24
Pseudohypoparathyroidism 1 | 17
Spinocerebellar ataxia type 7 1 | 13
Syphilis 1 | 18
Thrombocytopenia 1 | 105
Yaws 1 | 8
active ulcerative colitis 1 | 477
acute quadriplegic myopathy 1 | 1,157
breast carcinoma 1 | 1,614
colon cancer 1 | 1,475
dermatomyositis 1 | 933
fascioscapulohumeral muscular dystrophy 1 | 100
glioblastoma multiforme 1 | 347
head and neck cancer 1 | 270
non-Hodgkin lymphoma 1 | 2
non-small cell lung cancer 1 | 2,798
non-small cell lung carcinoma 1 | 413
pancreatic carcinoma 1 | 567
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,795
pediatric high grade glioma 1 | 2,712
primary pancreatic ductal adenocarcinoma 1 | 1,271
sonic hedgehog group medulloblastoma 1 | 1,482
spina bifida 1 | 1,064
tuberculosis 1 | 1,557

Tissue

Blood and immune system 12 | 17,995
Cardiovascular System 12 | 17,958
Digestive Tract 12 | 18,473
Endocrine System 12 | 18,512
Female tissues 12 | 18,647
Liver and Pancreas 12 | 18,136
Male tissues 12 | 17,969
Nervous System 12 | 18,561
Respiratory system 12 | 17,484
Skin and soft tissues 12 | 18,115
Urinary Tract 12 | 18,444

Target Family

Non-IDG 8 | 11,971
Epigenetic 2 | 242
Kinase 2 | 634

GO Component

actomyosin 12 | 12
nucleus 5,107 | 5,107
cytoplasm 4,985 | 4,985
plasma membrane 4,118 | 4,118
integral component of membrane 3,679 | 3,679
cytosol 3,265 | 3,265
extracellular exosome 2,758 | 2,758
nucleoplasm 2,717 | 2,717
membrane 1,906 | 1,906
extracellular region 1,493 | 1,493
integral component of plasma m... 1,406 | 1,406
extracellular space 1,304 | 1,304
mitochondrion 1,231 | 1,231
Golgi apparatus 864 | 864
endoplasmic reticulum 859 | 859
endoplasmic reticulum membrane 848 | 848
nucleolus 815 | 815
Golgi membrane 659 | 659
perinuclear region of cytoplas... 611 | 611
cell surface 594 | 594
intracellular 548 | 548
intracellular membrane-bounded... 537 | 537
cell junction 451 | 451
mitochondrial inner membrane 425 | 425
centrosome 409 | 409
focal adhesion 383 | 383
protein complex 355 | 355
cytoskeleton 343 | 343
dendrite 329 | 329
mitochondrial matrix 322 | 322
cell-cell adherens junction 307 | 307
neuronal cell body 303 | 303
microtubule 294 | 294
lysosomal membrane 278 | 278
apical plasma membrane 277 | 277
proteinaceous extracellular ma... 244 | 244
neuron projection 229 | 229
nuclear membrane 218 | 218
early endosome 217 | 217
axon 214 | 214
lysosome 210 | 210
endosome 208 | 208
actin cytoskeleton 205 | 205
external side of plasma membra... 205 | 205
postsynaptic membrane 204 | 204
extracellular matrix 198 | 198
nuclear speck 197 | 197
membrane raft 196 | 196
endoplasmic reticulum lumen 192 | 192
transcription factor complex 184 | 184
endosome membrane 182 | 182
early endosome membrane 180 | 180
basolateral plasma membrane 174 | 174
nuclear chromatin 169 | 169
synapse 166 | 166
cell-cell junction 161 | 161
nuclear envelope 156 | 156
lamellipodium 153 | 153
mitochondrial outer membrane 148 | 148
blood microparticle 147 | 147
myelin sheath 144 | 144
postsynaptic density 144 | 144
cytoplasmic vesicle 143 | 143
microtubule organizing center 137 | 137
cytoplasmic, membrane-bounded ... 132 | 132
ER to Golgi transport vesicle ... 131 | 131
microtubule cytoskeleton 127 | 127
receptor complex 127 | 127
phagocytic vesicle membrane 126 | 126
cytoplasmic vesicle membrane 125 | 125
midbody 125 | 125
trans-Golgi network 124 | 124
cell cortex 119 | 119
cilium 118 | 118
late endosome 116 | 116
spindle 116 | 116
intracellular ribonucleoprotei... 114 | 114
vesicle 112 | 112
Z disc 110 | 110
bicellular tight junction 110 | 110
anchored component of membrane 109 | 109
growth cone 109 | 109
integral component of lumenal ... 108 | 108
late endosome membrane 107 | 107
endomembrane system 106 | 106
centriole 105 | 105
recycling endosome 104 | 104
spindle pole 104 | 104
perikaryon 103 | 103
integral component of endoplas... 101 | 101
intermediate filament 101 | 101
melanosome 101 | 101
chromosome 100 | 100
dendritic spine 99 | 99
ubiquitin ligase complex 99 | 99
peroxisome 98 | 98
nuclear matrix 97 | 97
PML body 94 | 94
Golgi lumen 93 | 93
keratin filament 93 | 93
trans-Golgi network membrane 92 | 92

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Unconventional myosin-Va MYO5A Tbio Non-IDG -1.70632 48.8 66
Serine/threonine-protein kinase MRCK beta CDC42BPB Tbio Kinase -0.58062 3.94 105
Myosin-10 MYH10 Tbio Non-IDG -1.72956 52.1 86
Myosin-9 MYH9 Tbio Non-IDG -2.97983 996.7 305
Serine/threonine-protein kinase MRCK alpha CDC42BPA Tchem Kinase -1.26503 21.4 151
Unconventional myosin-XVIIIa MYO18A Tbio Non-IDG -1.12753 13.6 32
Histone acetyltransferase KAT2B KAT2B Tchem Epigenetic -2.59423 357.3 318
Myosin-14 MYH14 Tbio Non-IDG -1.34540 22.1 167
Histone deacetylase 4 HDAC4 Tclin Epigenetic -2.35585 236.0 715
Drebrin DBN1 Tbio Non-IDG -2.01173 126.5 197