Development Level

Tbio 7 | 10,625

IMPC Phenotype

decreased bone mineral density 1 | 126
decreased circulating creatini... 1 | 31
decreased circulating insulin ... 1 | 75
decreased monocyte cell number 1 | 28
increased circulating alkaline... 1 | 119
increased circulating phosphat... 1 | 24
increased grip strength 1 | 83

Disease

intraductal papillary-mucinous adenoma (IPMA) 5 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,289
ovarian cancer 5 | 8,491
ulcerative colitis 5 | 2,087
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,988
interstitial cystitis 3 | 2,299
invasive ductal carcinoma 3 | 2,950
lung adenocarcinoma 3 | 2,714
lung carcinoma 3 | 2,844
osteosarcoma 3 | 7,933
pancreatic cancer 3 | 2,300
cystic fibrosis 2 | 1,670
ductal carcinoma in situ 2 | 1,745
esophageal adenocarcinoma 2 | 737
glioblastoma 2 | 5,572
group 4 medulloblastoma 2 | 1,875
lung cancer 2 | 4,473
non-inflammatory breast cancer 2 | 208
non-small cell lung cancer 2 | 2,798
psoriasis 2 | 6,685
spina bifida 2 | 1,064
Alpha-B Crystallinopathy 1 | 1
Atopic dermatitis 1 | 944
BONE MINERAL DENSITY QUANTITATIVE TRAIT LOCUS 18 1 | 1
Barrett's esophagus 1 | 185
Breast cancer 1 | 3,098
CARDIOMYOPATHY, DILATED, 1II 1 | 1
CATARACT, MARNER TYPE 1 | 6
Cancer 1 | 2,346
Cardiomyopathy 1 | 110
Cardiomyopathy, Hypertrophic, Familial 1 | 21
Cardiomyopathy, dilated 1II 1 | 1
Cataract 1 | 104
Cataract 16, multiple types 1 | 1
Cataract, Posterior Polar, 2 1 | 1
Choroid Plexus Carcinoma 1 | 4
Choroid Plexus Papilloma 1 | 10
Colonic Neoplasms 1 | 126
Dacryoadenitis 1 | 7
Degenerative polyarthritis 1 | 93
Dilated cardiomyopathy 1 | 51
Down syndrome 1 | 548
Duchenne muscular dystrophy 1 | 602
Endometriosis 1 | 535
Esophageal Neoplasms 1 | 67
Familial isolated dilated cardiomyopathy 1 | 41
IGA Glomerulonephritis 1 | 454
Idiopathic scoliosis 1 | 29
Lateral sclerosis 1 | 13
Liver neoplasms 1 | 108
Mouth Neoplasms 1 | 44
Multiple Sclerosis 1 | 498
Muscular atrophy 1 | 67
Mycosis fungoides 1 | 30
Myopathy 1 | 128
Myopathy, myofibrillar, 2 1 | 1
Myopathy, myofibrillar, fatal infantile hypertonic, alpha-B crystallin-related 1 | 1
Neurodegenerative Disorders 1 | 37
Osteogenesis imperfecta 1 | 34
Osteoporosis 1 | 259
Pearson syndrome 1 | 17
Pick disease 1 | 1,893
Prostatic Neoplasms 1 | 471
Renal Cell Carcinoma 1 | 199
Rheumatoid Arthritis 1 | 1,170
Sezary's disease 1 | 11
Spinal muscular atrophy 1 | 24
Squamous cell carcinoma 1 | 96
Tobacco Use Disorder 1 | 10
Tongue Neoplasms 1 | 8
X-linked cerebral adrenoleukodystrophy 1 | 115
active Crohn's disease 1 | 918
acute myeloid leukemia 1 | 785
astrocytoma 1 | 1,493
atypical teratoid / rhabdoid tumor 1 | 4,369
atypical teratoid/rhabdoid tumor 1 | 1,095
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 499
breast carcinoma 1 | 1,614
chronic lymphosyte leukemia 1 | 232
colon cancer 1 | 1,475
dermatomyositis 1 | 966
diabetes mellitus 1 | 1,663
dilated cardiomyopathy 1II 1 | 1
fibroadenoma 1 | 557
inflammatory breast cancer 1 | 404
juvenile dermatomyositis 1 | 1,189
medulloblastoma, large-cell 1 | 6,234
nasopharyngeal carcinoma 1 | 1,056
nephrosclerosis 1 | 329
non-small cell lung carcinoma 1 | 413
pancreatic carcinoma 1 | 567
pilocytic astrocytoma 1 | 3,086
pituitary cancer 1 | 1,972
posterior fossa group A ependymoma 1 | 1,511
primary Sjogren syndrome 1 | 788
primary pancreatic ductal adenocarcinoma 1 | 1,271
primitive neuroectodermal tumor 1 | 3,031
progressive supranuclear palsy 1 | 674
sonic hedgehog group medulloblastoma 1 | 1,482
tuberculosis and treatment for 6 months 1 | 686

Tissue

Blood and immune system 7 | 17,994
Cardiovascular System 7 | 17,957
Digestive Tract 7 | 18,472
Endocrine System 7 | 18,511
Female tissues 7 | 18,646
Liver and Pancreas 7 | 18,135
Male tissues 7 | 17,968
Nervous System 7 | 18,560
Respiratory system 7 | 17,483
Skin and soft tissues 7 | 18,114
Urinary Tract 7 | 18,443

Target Family

Non-IDG 7 | 11,969

GO Component

actin filament bundle 7 | 7
nucleus 5,106 | 5,106
cytoplasm 4,984 | 4,984
plasma membrane 4,118 | 4,118
integral component of membrane 3,679 | 3,679
cytosol 3,264 | 3,264
extracellular exosome 2,757 | 2,757
nucleoplasm 2,716 | 2,716
membrane 1,906 | 1,906
extracellular region 1,493 | 1,493
integral component of plasma m... 1,406 | 1,406
extracellular space 1,304 | 1,304
mitochondrion 1,231 | 1,231
Golgi apparatus 864 | 864
endoplasmic reticulum 859 | 859
endoplasmic reticulum membrane 848 | 848
nucleolus 815 | 815
Golgi membrane 659 | 659
perinuclear region of cytoplas... 611 | 611
cell surface 594 | 594
intracellular 548 | 548
intracellular membrane-bounded... 536 | 536
cell junction 451 | 451
mitochondrial inner membrane 425 | 425
centrosome 409 | 409
focal adhesion 383 | 383
protein complex 355 | 355
cytoskeleton 343 | 343
dendrite 329 | 329
mitochondrial matrix 322 | 322
cell-cell adherens junction 307 | 307
neuronal cell body 303 | 303
microtubule 294 | 294
lysosomal membrane 278 | 278
apical plasma membrane 277 | 277
proteinaceous extracellular ma... 244 | 244
neuron projection 229 | 229
nuclear membrane 218 | 218
early endosome 217 | 217
axon 214 | 214
lysosome 210 | 210
endosome 208 | 208
actin cytoskeleton 205 | 205
external side of plasma membra... 205 | 205
postsynaptic membrane 204 | 204
extracellular matrix 198 | 198
nuclear speck 197 | 197
membrane raft 196 | 196
endoplasmic reticulum lumen 192 | 192
transcription factor complex 184 | 184
endosome membrane 182 | 182
early endosome membrane 180 | 180
basolateral plasma membrane 174 | 174
nuclear chromatin 169 | 169
synapse 166 | 166
cell-cell junction 161 | 161
nuclear envelope 156 | 156
lamellipodium 153 | 153
mitochondrial outer membrane 148 | 148
blood microparticle 147 | 147
myelin sheath 144 | 144
postsynaptic density 144 | 144
cytoplasmic vesicle 143 | 143
microtubule organizing center 137 | 137
cytoplasmic, membrane-bounded ... 132 | 132
ER to Golgi transport vesicle ... 131 | 131
microtubule cytoskeleton 127 | 127
receptor complex 127 | 127
phagocytic vesicle membrane 126 | 126
cytoplasmic vesicle membrane 125 | 125
midbody 125 | 125
trans-Golgi network 124 | 124
cell cortex 119 | 119
cilium 118 | 118
late endosome 116 | 116
spindle 116 | 116
intracellular ribonucleoprotei... 114 | 114
vesicle 112 | 112
Z disc 110 | 110
bicellular tight junction 110 | 110
anchored component of membrane 109 | 109
growth cone 109 | 109
integral component of lumenal ... 108 | 108
late endosome membrane 107 | 107
endomembrane system 106 | 106
centriole 105 | 105
recycling endosome 104 | 104
spindle pole 104 | 104
perikaryon 103 | 103
integral component of endoplas... 101 | 101
intermediate filament 101 | 101
melanosome 101 | 101
chromosome 100 | 100
dendritic spine 99 | 99
ubiquitin ligase complex 99 | 99
peroxisome 98 | 98
nuclear matrix 97 | 97
PML body 94 | 94
Golgi lumen 93 | 93
keratin filament 93 | 93
trans-Golgi network membrane 92 | 92

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Filamin-interacting protein FAM101A RFLNA Tbio Non-IDG -0.95944 9.37 82
Filamin-interacting protein FAM101B RFLNB Tbio Non-IDG -0.79131 4.99 15
Villin-1 VIL1 Tbio Non-IDG -2.18134 153.7 231
Plastin-2 LCP1 Tbio Non-IDG -2.20011 165.4 215
Plastin-3 PLS3 Tbio Non-IDG -1.80716 68.2 117
Alpha-crystallin B chain CRYAB Tbio Non-IDG -2.26485 179.8 999
Plastin-1 PLS1 Tbio Non-IDG -2.35004 223.3 92