Development Level

Tbio 7 | 11,651

IMPC Phenotype

abnormal coat appearance 1 | 31
abnormal sleep behavior 1 | 70
decreased bone mineral density 1 | 126
decreased circulating insulin ... 1 | 76
increased circulating phosphat... 1 | 26
increased fasted circulating g... 1 | 76
preweaning lethality, complete... 1 | 979

Disease

ovarian cancer 5 | 8,520
Carcinoma 4 | 11,493
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
ulcerative colitis 4 | 1,819
Breast cancer 3 | 3,578
atypical teratoid / rhabdoid tumor 3 | 5,112
glioblastoma 3 | 5,792
invasive ductal carcinoma 3 | 2,951
lung adenocarcinoma 3 | 2,716
lung carcinoma 3 | 2,843
non-small cell lung cancer 3 | 2,890
osteosarcoma 3 | 7,950
pancreatic cancer 3 | 2,398
psoriasis 3 | 6,694
Astrocytoma, Pilocytic 2 | 3,081
Cancer 2 | 2,499
Cholestasis 2 | 155
Duchenne muscular dystrophy 2 | 601
Liver Cirrhosis, Experimental 2 | 769
Rheumatoid arthritis 2 | 1,191
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
cystic fibrosis 2 | 1,696
ductal carcinoma in situ 2 | 1,745
ependymoma 2 | 4,679
esophageal adenocarcinoma 2 | 737
group 3 medulloblastoma 2 | 4,104
juvenile dermatomyositis 2 | 1,187
lung cancer 2 | 4,740
medulloblastoma, large-cell 2 | 6,241
pituitary cancer 2 | 1,972
primitive neuroectodermal tumor 2 | 3,035
spina bifida 2 | 1,074
Adenoid Cystic Carcinoma 1 | 99
Adult onset 1 | 82
Amyotrophic lateral sclerosis 1 | 451
Atopic dermatitis 1 | 952
Autistic Disorder 1 | 364
Barrett's esophagus 1 | 182
CATARACT 16, MULTIPLE TYPES 1 | 15
Carcinoma, Adenoid Cystic 1 | 99
Carcinoma, Renal Cell 1 | 124
Carcinoma, Squamous Cell 1 | 110
Cardiomyopathy 1 | 116
Cardiomyopathy, Dilated 1 | 83
Colonic Neoplasms 1 | 142
Contracture 1 | 96
Contracture of joint 1 | 93
Creatine phosphokinase serum increased 1 | 110
Degenerative polyarthritis 1 | 115
Dilated cardiomyopathy 1 | 56
Distal limb muscle weakness due to peripheral neuropathy 1 | 62
Distal muscle weakness 1 | 62
Elevated creatine kinase 1 | 110
Esophageal Neoplasms 1 | 69
Flexion contracture 1 | 93
Flexion contractures of joints 1 | 93
Generalized osteopenia 1 | 99
Hypertrophic Cardiomyopathy 1 | 117
Limb-girdle muscle weakness 1 | 12
Liver neoplasms 1 | 130
Lung Neoplasms 1 | 232
Mitral valve insufficiency 1 | 49
Mouth Neoplasms 1 | 55
Multiple Sclerosis 1 | 540
Muscle biopsy shows dystrophic changes 1 | 39
Muscular atrophy 1 | 71
Muscular dystrophy 1 | 75
Myopathy 1 | 185
Neck muscle weakness 1 | 17
Neurodegenerative Disorders 1 | 79
Nuclear cataract 1 | 19
Nuclear non-senile cataract 1 | 18
Osteoarthritis 1 | 184
Osteogenesis imperfecta 1 | 34
Osteopenia 1 | 99
Osteoporosis 1 | 363
Pearson syndrome 1 | 19
Renal Cell Carcinoma 1 | 214
Respiratory Failure 1 | 104
Salivary Gland Neoplasms 1 | 46
Slow progression 1 | 89
Spinal muscular atrophy 1 | 34
Squamous cell carcinoma 1 | 129
Syndromic X-linked intellectual disability Najm type 1 | 3
Type 2 diabetes mellitus 1 | 272
X-linked cerebral adrenoleukodystrophy 1 | 116
X-linked dominant 1 | 57
active Crohn's disease 1 | 922
active ulcerative colitis 1 | 764
breast carcinoma 1 | 1,638
chronic kidney disease 1 | 90
fascioscapulohumeral muscular dystrophy 1 | 100
inflammatory breast cancer 1 | 286
non-small cell lung carcinoma 1 | 317
pediatric high grade glioma 1 | 1,064
sarcoidosis 1 | 370
tuberculosis 1 | 2,010

Tissue

Blood and immune system 7 | 16,909
Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Male tissues 7 | 17,142
Nervous System 7 | 16,725
Respiratory system 7 | 16,393
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678
Cardiovascular System 6 | 15,192

Target Family

Non-IDG 6 | 12,091
Enzyme 1 | 4,145

GO Component

actin filament bundle 7 | 7
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Alpha-crystallin B chain CRYAB Tbio Non-IDG -2.29243 192.0 1100
Plastin-2 LCP1 Tbio Non-IDG -2.22829 176.7 267
Plastin-3 PLS3 Tbio Non-IDG -1.86303 77.6 132
Villin-1 VIL1 Tbio Non-IDG -2.20137 162.5 349
Myristoylated alanine-rich C-kinase substrate MARCKS Tbio Enzyme -2.67762 525.7 663
Plastin-1 PLS1 Tbio Non-IDG -2.36731 223.6 103
Refilin-B RFLNB Tbio Non-IDG -0.79131 5.72 19