Development Level

Tbio 44 | 11,445
Tclin 4 | 613
Tchem 2 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 4 | 979
decreased bone mineral density 2 | 126
hypoactivity 2 | 132
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal femur morphology 1 | 14
abnormal sleep behavior 1 | 70
cardiovascular system phenotyp... 1 | 36
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased caudal vertebrae num... 1 | 53
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
decreased heart rate variabili... 1 | 13
decreased lymphocyte cell numb... 1 | 83
decreased spleen weight 1 | 10
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased circulating alkaline... 1 | 122
increased circulating phosphat... 1 | 26
increased fasted circulating g... 1 | 76
increased startle reflex 1 | 112
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
prolonged PR interval 1 | 15
short tibia 1 | 97

Disease

Carcinoma 43 | 11,493
osteosarcoma 33 | 7,950
psoriasis 29 | 6,694
ovarian cancer 27 | 8,520
glioblastoma 25 | 5,792
medulloblastoma, large-cell 19 | 6,241
Astrocytoma, Pilocytic 18 | 3,081
atypical teratoid / rhabdoid tumor 18 | 5,112
Breast cancer 17 | 3,578
ependymoma 16 | 4,679
invasive ductal carcinoma 16 | 2,951
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,291
lung cancer 15 | 4,740
pancreatic cancer 15 | 2,398
primitive neuroectodermal tumor 15 | 3,035
group 3 medulloblastoma 14 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,955
lung carcinoma 14 | 2,843
Kidney cancer 13 | 2,613
subependymal giant cell astrocytoma 13 | 2,287
Cancer 12 | 2,499
Liver Cirrhosis, Experimental 12 | 769
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
non-small cell lung cancer 12 | 2,890
ulcerative colitis 12 | 1,819
interstitial cystitis 11 | 2,312
malignant mesothelioma 11 | 3,232
adult high grade glioma 10 | 3,801
lung adenocarcinoma 10 | 2,716
oligodendroglioma 10 | 2,850
spina bifida 10 | 1,074
ductal carcinoma in situ 9 | 1,745
tuberculosis 9 | 2,010
acute quadriplegic myopathy 8 | 1,158
adrenocortical carcinoma 8 | 1,428
group 4 medulloblastoma 8 | 1,855
juvenile dermatomyositis 8 | 1,187
pediatric high grade glioma 8 | 1,064
Duchenne muscular dystrophy 7 | 601
Pick disease 7 | 1,894
Recurrent respiratory infections 7 | 141
astrocytoma 7 | 1,146
colon cancer 7 | 1,478
Cardiomyopathy, Dilated 6 | 83
astrocytic glioma 6 | 2,597
cutaneous lupus erythematosus 6 | 1,057
cystic fibrosis 6 | 1,696
diabetes mellitus 6 | 1,728
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
primary pancreatic ductal adenocarcinoma 6 | 1,109
Animal Mammary Neoplasms 5 | 136
Autosomal recessive predisposition 5 | 1,442
Byzanthine arch palate 5 | 194
Mammary Neoplasms, Animal 5 | 136
Nemaline myopathy 5 | 17
Prostatic Neoplasms 5 | 495
Rheumatoid arthritis 5 | 1,191
Schizophrenia 5 | 1,160
pituitary cancer 5 | 1,972
primary Sjogren syndrome 5 | 735
Acquired scoliosis 4 | 281
Blepharoptosis 4 | 231
Cognitive delay 4 | 608
Curvature of spine 4 | 282
Dilated cardiomyopathy 4 | 56
Down syndrome 4 | 499
Failure to gain weight 4 | 365
Feeding difficulties in infancy 4 | 175
Global developmental delay 4 | 608
Liver cancer 4 | 604
Mammary Neoplasms, Experimental 4 | 154
Mental and motor retardation 4 | 608
Motor delay 4 | 147
Muscle hypotonia 4 | 571
Myopathy 4 | 185
Neonatal Hypotonia 4 | 64
No development of motor milestones 4 | 147
Osteoporosis 4 | 363
Pectus excavatum 4 | 100
Pediatric failure to thrive 4 | 365
Renal Cell Carcinoma 4 | 214
Stomach Neoplasms 4 | 300
Weight Gain 4 | 100
acute myeloid leukemia 4 | 783
dermatomyositis 4 | 966
fibroadenoma 4 | 559
pancreatic carcinoma 4 | 562
periodontitis 4 | 293
Amyotrophic lateral sclerosis 3 | 451
Bell Palsy 3 | 58
Facial Paresis 3 | 59
Facial muscle weakness of muscles innervated by CN VII 3 | 58
Kidney disease 3 | 430
Lumbar lordosis 3 | 35
Variable expressivity 3 | 157
active Crohn's disease 3 | 922
aldosterone-producing adenoma 3 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
breast carcinoma 3 | 1,638
medulloblastoma 3 | 720

Tissue

Digestive Tract 51 | 17,369
Endocrine System 51 | 18,159
Liver and Pancreas 51 | 16,750
Male tissues 51 | 17,142
Skin and soft tissues 51 | 17,230
Urinary Tract 51 | 16,678
Blood and immune system 50 | 16,909
Female tissues 50 | 17,400
Cardiovascular System 49 | 15,192
Nervous System 49 | 16,725
Respiratory system 48 | 16,393

Target Family

Non-IDG 40 | 12,091
Enzyme 5 | 4,145
Kinase 5 | 634
GPCR 1 | 408

GO Component

actin filament 51 | 51
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Palladin PALLD Tbio Non-IDG -2.73002 528.8 164
Adenomatous polyposis coli protein 2 APC2 Tbio Non-IDG -1.50271 33.3 93
Serine/threonine-protein kinase MARK2 MARK2 Tchem Kinase -2.49873 272.3 322
Rho GTPase-activating protein 6 ARHGAP6 Tbio Enzyme -0.85601 8.06 45
Glycerophosphoinositol inositolphosphodiesterase GDPD2 GDPD2 Tbio Enzyme -0.91821 8.09 101
Coronin-1B CORO1B Tbio Non-IDG -1.09320 13.6 149
Leiomodin-2 LMOD2 Tbio Non-IDG -0.89671 9.37 55
Growth arrest-specific protein 2 GAS2 Tbio Non-IDG -1.70451 49.0 218
Unconventional myosin-IXb MYO9B Tbio Non-IDG -1.68591 55.7 79
Actin, cytoplasmic 2 ACTG1 Tbio Non-IDG -2.50312 297.3 225