Development Level

Tbio 160 | 10,625
Tchem 22 | 1,890
Tdark 20 | 7,003
Tclin 3 | 602

Collection

Ion Channel: IDG Consortium (Targets) 3 | 102
Kinase: IDG Consortium (Complete/Control) 1 | 37
Kinase: IDG Consortium (Targets) 1 | 125

IMPC Phenotype

preweaning lethality, complete... 11 | 633
preweaning lethality, incomple... 7 | 260
abnormal bone structure 4 | 131
decreased grip strength 4 | 123
decreased total body fat amoun... 4 | 186
abnormal behavior 3 | 226
abnormal embryo size 3 | 112
abnormal sleep behavior 3 | 63
decreased body weight 3 | 174
decreased circulating HDL chol... 3 | 77
decreased circulating choleste... 3 | 85
decreased circulating glucose ... 3 | 121
decreased lean body mass 3 | 195
improved glucose tolerance 3 | 56
increased body weight 3 | 42
increased heart weight 3 | 37
increased lean body mass 3 | 107
abnormal QRS complex 2 | 25
abnormal coat-hair pigmentatio... 2 | 54
decreased bone mineral content 2 | 157
decreased circulating alanine ... 2 | 53
decreased circulating fructosa... 2 | 31
decreased circulating serum al... 2 | 79
decreased circulating triglyce... 2 | 83
decreased fasted circulating g... 2 | 49
edema 2 | 11
embryonic lethality prior to o... 2 | 148
embryonic lethality prior to t... 2 | 187
enlarged heart 2 | 111
hyperactivity 2 | 108
increased circulating alkaline... 2 | 119
increased exploration in new e... 2 | 56
increased or absent threshold ... 2 | 128
increased red blood cell distr... 2 | 21
increased total body fat amoun... 2 | 57
prenatal lethality prior to he... 2 | 64
abnormal cornea morphology 1 | 24
abnormal eye anterior chamber ... 1 | 3
abnormal eye morphology 1 | 38
abnormal eye size 1 | 11
abnormal gait 1 | 51
abnormal head morphology 1 | 10
abnormal liver morphology 1 | 5
abnormal respiratory quotient 1 | 9
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal rib morphology 1 | 28
abnormal skin coloration 1 | 18
abnormal skin morphology 1 | 23
abnormal spleen morphology 1 | 36
abnormal testis morphology 1 | 30
abnormal vertebrae morphology 1 | 14
abnormal vibrissa morphology 1 | 17
absent startle reflex 1 | 15
absent teeth 1 | 4
decreased Ly6C low monocyte nu... 1 | 23
decreased NK T cell number 1 | 28
decreased body length 1 | 108
decreased circulating LDL chol... 1 | 37
decreased circulating calcium ... 1 | 33
decreased circulating creatini... 1 | 31
decreased circulating potassiu... 1 | 17
decreased effector memory CD8-... 1 | 24
decreased eosinophil cell numb... 1 | 41
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular vol... 1 | 50
decreased mean platelet volume 1 | 12
decreased prepulse inhibition 1 | 52
decreased rib number 1 | 59
decreased spleen weight 1 | 13
decreased startle reflex 1 | 48
decreased total retina thickne... 1 | 20
decreased vertical activity 1 | 22
enlarged spleen 1 | 26
hemorrhage 1 | 12
hypoactivity 1 | 89
impaired glucose tolerance 1 | 52
increased bone mineral content 1 | 92
increased circulating calcium ... 1 | 32
increased circulating chloride... 1 | 43
increased circulating creatini... 1 | 29
increased circulating potassiu... 1 | 31
increased circulating serum al... 1 | 25
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 20
increased coping response 1 | 3
increased erythrocyte cell num... 1 | 26
increased fasted circulating g... 1 | 68
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
increased respiratory quotient 1 | 12
limb grasping 1 | 35
microphthalmia 1 | 15
prenatal lethality 1 | 16
shortened PQ interval 1 | 6
shortened ST segment 1 | 9
small testis 1 | 37
small thymus 1 | 11
vertebral fusion 1 | 23

Disease

osteosarcoma 117 | 7,933
ovarian cancer 115 | 8,491
glioblastoma 95 | 5,572
medulloblastoma, large-cell 89 | 6,234
psoriasis 85 | 6,685
atypical teratoid / rhabdoid tumor 76 | 4,369
lung cancer 73 | 4,473
pediatric high grade glioma 62 | 2,712
malignant mesothelioma 60 | 3,163
intraductal papillary-mucinous neoplasm (IPMN) 59 | 3,289
Breast cancer 57 | 3,098
invasive ductal carcinoma 56 | 2,950
pancreatic cancer 56 | 2,300
pilocytic astrocytoma 56 | 3,086
primitive neuroectodermal tumor 56 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 49 | 2,988
non-small cell lung cancer 49 | 2,798
intraductal papillary-mucinous adenoma (IPMA) 46 | 2,956
Cancer 41 | 2,346
oligodendroglioma 41 | 2,849
lung adenocarcinoma 40 | 2,714
primary pancreatic ductal adenocarcinoma 40 | 1,271
Carcinoma 38 | 2,147
lung carcinoma 38 | 2,844
group 4 medulloblastoma 37 | 1,875
ependymoma 36 | 2,514
subependymal giant cell astrocytoma 34 | 2,287
breast carcinoma 33 | 1,614
colon cancer 33 | 1,475
astrocytic glioma 32 | 2,241
juvenile dermatomyositis 31 | 1,189
ductal carcinoma in situ 30 | 1,745
interstitial cystitis 30 | 2,299
pituitary cancer 29 | 1,972
medulloblastoma 28 | 1,524
cystic fibrosis 27 | 1,670
posterior fossa group A ependymoma 27 | 1,511
spina bifida 27 | 1,064
adrenocortical carcinoma 26 | 1,427
tuberculosis 26 | 1,563
ulcerative colitis 26 | 2,087
diabetes mellitus 25 | 1,663
Pick disease 24 | 1,893
astrocytoma 23 | 1,493
acute quadriplegic myopathy 22 | 1,157
group 3 medulloblastoma 22 | 2,254
posterior fossa group B ependymoma 22 | 1,530
sonic hedgehog group medulloblastoma 21 | 1,482
dermatomyositis 20 | 966
Alzheimer's disease 19 | 644
Duchenne muscular dystrophy 19 | 602
Rheumatoid Arthritis 19 | 1,170
Waldenstrons macroglobulinemia 18 | 764
adult high grade glioma 18 | 2,148
autosomal dominant Emery-Dreifuss muscular dystrophy 18 | 499
Multiple myeloma 17 | 1,327
nasopharyngeal carcinoma 17 | 1,056
pancreatic ductal adenocarcinoma liver metastasis 17 | 1,795
tuberculosis and treatment for 6 months 16 | 686
atypical teratoid/rhabdoid tumor 15 | 1,095
cutaneous lupus erythematosus 15 | 1,056
esophageal adenocarcinoma 14 | 737
gastric carcinoma 14 | 832
hepatocellular carcinoma 13 | 550
hereditary spastic paraplegia 13 | 313
Amyotrophic Lateral Sclerosis 12 | 432
aldosterone-producing adenoma 12 | 664
pancreatic carcinoma 12 | 567
primary Sjogren syndrome 12 | 788
progressive supranuclear palsy 12 | 674
Down syndrome 11 | 548
non primary Sjogren syndrome sicca 11 | 840
Atopic dermatitis 10 | 944
fibroadenoma 10 | 557
gastric cancer 10 | 436
Bipolar Disorder 9 | 266
Endometriosis 9 | 535
Mammary Neoplasms 9 | 410
Prostatic Neoplasms 9 | 471
active Crohn's disease 9 | 918
mucosa-associated lymphoid tissue lymphoma 9 | 480
IGA Glomerulonephritis 8 | 454
Schizophrenia 8 | 503
active ulcerative colitis 8 | 477
tuberculosis and treatment for 3 months 8 | 327
Obesity 7 | 616
Wiskott-Aldrich syndrome 7 | 27
COPD 6 | 116
Leukemia, Myelocytic, Acute 6 | 113
Weight Gain 6 | 87
acute myeloid leukemia 6 | 785
head and neck cancer 6 | 270
inflammatory breast cancer 6 | 404
interstitial lung disease 6 | 292
non diabetic and post-ischemic heart failure 6 | 200
sarcoidosis 6 | 368
urothelial carcinoma 6 | 318
Becker muscular dystrophy 5 | 187
Juvenile arthritis 5 | 124
Myocardial Ischemia 5 | 169

Tissue

Blood and immune system 205 | 17,994
Cardiovascular System 205 | 17,957
Digestive Tract 205 | 18,472
Endocrine System 205 | 18,511
Female tissues 205 | 18,646
Liver and Pancreas 205 | 18,135
Male tissues 205 | 17,968
Nervous System 205 | 18,560
Respiratory system 204 | 17,483
Urinary Tract 204 | 18,443
Skin and soft tissues 201 | 18,114

Target Family

Non-IDG 153 | 11,969
Enzyme 26 | 4,146
Kinase 10 | 634
Transcription Factor 9 | 1,400
Ion Channel 3 | 341
Transporter 2 | 473
GPCR 1 | 408
Nuclear Receptor 1 | 48

GO Component

actin cytoskeleton 205 | 205
nucleus 5,106 | 5,106
cytoplasm 4,984 | 4,984
plasma membrane 4,118 | 4,118
integral component of membrane 3,679 | 3,679
cytosol 3,264 | 3,264
extracellular exosome 2,757 | 2,757
nucleoplasm 2,716 | 2,716
membrane 1,906 | 1,906
extracellular region 1,493 | 1,493
integral component of plasma m... 1,406 | 1,406
extracellular space 1,304 | 1,304
mitochondrion 1,231 | 1,231
Golgi apparatus 864 | 864
endoplasmic reticulum 859 | 859
endoplasmic reticulum membrane 848 | 848
nucleolus 815 | 815
Golgi membrane 659 | 659
perinuclear region of cytoplas... 611 | 611
cell surface 594 | 594
intracellular 548 | 548
intracellular membrane-bounded... 536 | 536
cell junction 451 | 451
mitochondrial inner membrane 425 | 425
centrosome 409 | 409
focal adhesion 383 | 383
protein complex 355 | 355
cytoskeleton 343 | 343
dendrite 329 | 329
mitochondrial matrix 322 | 322
cell-cell adherens junction 307 | 307
neuronal cell body 303 | 303
microtubule 294 | 294
lysosomal membrane 278 | 278
apical plasma membrane 277 | 277
proteinaceous extracellular ma... 244 | 244
neuron projection 229 | 229
nuclear membrane 218 | 218
early endosome 217 | 217
axon 214 | 214
lysosome 210 | 210
endosome 208 | 208
external side of plasma membra... 205 | 205
postsynaptic membrane 204 | 204
extracellular matrix 198 | 198
nuclear speck 197 | 197
membrane raft 196 | 196
endoplasmic reticulum lumen 192 | 192
transcription factor complex 184 | 184
endosome membrane 182 | 182
early endosome membrane 180 | 180
basolateral plasma membrane 174 | 174
nuclear chromatin 169 | 169
synapse 166 | 166
cell-cell junction 161 | 161
nuclear envelope 156 | 156
lamellipodium 153 | 153
mitochondrial outer membrane 148 | 148
blood microparticle 147 | 147
myelin sheath 144 | 144
postsynaptic density 144 | 144
cytoplasmic vesicle 143 | 143
microtubule organizing center 137 | 137
cytoplasmic, membrane-bounded ... 132 | 132
ER to Golgi transport vesicle ... 131 | 131
microtubule cytoskeleton 127 | 127
receptor complex 127 | 127
phagocytic vesicle membrane 126 | 126
cytoplasmic vesicle membrane 125 | 125
midbody 125 | 125
trans-Golgi network 124 | 124
cell cortex 119 | 119
cilium 118 | 118
late endosome 116 | 116
spindle 116 | 116
intracellular ribonucleoprotei... 114 | 114
vesicle 112 | 112
Z disc 110 | 110
bicellular tight junction 110 | 110
anchored component of membrane 109 | 109
growth cone 109 | 109
integral component of lumenal ... 108 | 108
late endosome membrane 107 | 107
endomembrane system 106 | 106
centriole 105 | 105
recycling endosome 104 | 104
spindle pole 104 | 104
perikaryon 103 | 103
integral component of endoplas... 101 | 101
intermediate filament 101 | 101
melanosome 101 | 101
chromosome 100 | 100
dendritic spine 99 | 99
ubiquitin ligase complex 99 | 99
peroxisome 98 | 98
nuclear matrix 97 | 97
PML body 94 | 94
Golgi lumen 93 | 93
keratin filament 93 | 93
trans-Golgi network membrane 92 | 92

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Actin-binding protein IPP IPP Tdark Non-IDG -2.89711 782.9 29
Myristoylated alanine-rich C-kinase substrate MARCKS Tbio Enzyme -2.67051 512.2 639
WAS/WASL-interacting protein family member 1 WIPF1 Tbio Non-IDG -2.00605 100.9 97
Influenza virus NS1A-binding protein IVNS1ABP Tbio Non-IDG -0.94782 10.1 76
Catenin alpha-2 CTNNA2 Tbio Non-IDG -1.97005 96.0 66
Niban-like protein 1 FAM129B Tbio Non-IDG -0.43933 4.02 90
Twinfilin-1 TWF1 Tbio Non-IDG -1.07756 12.2 177
Amiloride-sensitive sodium channel subunit delta SCNN1D Tbio Ion Channel -1.12710 8.72 179
Neurogenic locus notch homolog protein 3 NOTCH3 Tchem Non-IDG -2.63361 426.8 383
Neurabin-2 PPP1R9B Tbio Non-IDG 0.00000 0