Development Level

Tbio 5 | 11,445
Tchem 4 | 1,598
Tclin 1 | 613

IMPC Phenotype

abnormal bone mineralization 1 | 38
abnormal head morphology 1 | 10
abnormal startle reflex 1 | 15
increased bone mineral density 1 | 72
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
mammalian phenotype 1 | 17
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 10 | 11,493
Cancer 9 | 2,499
atypical teratoid / rhabdoid tumor 7 | 5,112
medulloblastoma, large-cell 7 | 6,241
osteosarcoma 7 | 7,950
glioblastoma 6 | 5,792
psoriasis 6 | 6,694
Kidney cancer 5 | 2,613
Schizophrenia 5 | 1,160
group 3 medulloblastoma 5 | 4,104
ovarian cancer 5 | 8,520
Breast cancer 4 | 3,578
Pick disease 4 | 1,894
adrenocortical carcinoma 4 | 1,428
diabetes mellitus 4 | 1,728
ependymoma 4 | 4,679
primitive neuroectodermal tumor 4 | 3,035
tuberculosis 4 | 2,010
Alzheimer's disease 3 | 658
Astrocytoma, Pilocytic 3 | 3,081
Connective tissue disease 3 | 62
Endometrial cancer 3 | 311
Hypoplastic mandible condyle 3 | 275
Intellectual disability 3 | 1,016
Large intestine cancer 3 | 126
Liver cancer 3 | 604
Lymphoma, Mantle-Cell 3 | 11
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse 3 | 12
Mandibular hypoplasia 3 | 275
Melanoma 3 | 711
Micrognathism 3 | 275
Osteoporosis 3 | 363
Parkinson's disease 3 | 392
Prostatic Neoplasms 3 | 495
Renal Cell Carcinoma 3 | 214
Skin cancer 3 | 469
adult high grade glioma 3 | 3,801
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
lung cancer 3 | 4,740
medulloblastoma 3 | 720
oligodendroglioma 3 | 2,850
osteoporosis-pseudoglioma syndrome 3 | 9
pancreatic cancer 3 | 2,398
Abdominal Pain 2 | 98
Abnormalities, Multiple 2 | 13
Abnormality of retinal pigmentation 2 | 111
Adenocarcinoma 2 | 122
Adenoma 2 | 167
Angle class 2 malocclusion 2 | 57
Angle class 3 malocclusion 2 | 57
Autistic Disorder 2 | 364
Big calvaria 2 | 147
Carcinoma of colon 2 | 32
Carcinoma, Hepatocellular 2 | 228
Colonic Neoplasms 2 | 142
Colorectal Neoplasms 2 | 243
Dementia 2 | 175
ENSP00000256078 2 | 30
Familial adenomatous polyposis 2 | 32
Headache 2 | 37
High forehead 2 | 102
Increased head circumference 2 | 147
Increased hepatocellular carcinoma risk 2 | 27
Increased incidence of hepatocellular carcinoma 2 | 27
Increased size of cranium 2 | 147
Increased size of skull 2 | 147
Infantile onset 2 | 238
Intestinal Neoplasms 2 | 12
Liver carcinoma 2 | 240
Liver neoplasms 2 | 130
Long philtrum 2 | 137
Lung Neoplasms 2 | 232
Lymphoid leukemia 2 | 160
Lynch syndrome 2 | 35
Malabsorption 2 | 82
Malocclusion 2 | 57
Mesothelioma, Malignant 2 | 105
Muscular atrophy 2 | 71
Nerve Degeneration 2 | 121
Osteoarthritis 2 | 184
Retinal pigment epithelial abnormality 2 | 111
Somatic mutation 2 | 61
Stomach Neoplasms 2 | 300
Tall forehead 2 | 102
Thin upper lip vermilion 2 | 67
Toxic encephalopathy 2 | 141
Uterine Cervical Neoplasm 2 | 25
Uterine Cervical Neoplasms 2 | 26
Vascular disease 2 | 319
astrocytoma 2 | 1,146
colon cancer 2 | 1,478
hepatocellular carcinoma 2 | 547
lung adenocarcinoma 2 | 2,716
non-small cell lung cancer 2 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pituitary cancer 2 | 1,972
posterior fossa group A ependymoma 2 | 468
spina bifida 2 | 1,074

Tissue

Blood and immune system 9 | 16,909
Cardiovascular System 9 | 15,192
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678
Respiratory system 8 | 16,393

Target Family

Non-IDG 7 | 12,091
Kinase 2 | 634
GPCR 1 | 408

GO Component

Wnt signalosome 10 | 10
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Low-density lipoprotein receptor-related protein 5 LRP5 Tbio Non-IDG -3.10429 1247.5 302
Adenomatous polyposis coli protein APC Tbio Non-IDG -1.90646 66.5 508
Frizzled-1 FZD1 Tbio GPCR -2.07049 78.4 286
Glycogen synthase kinase-3 beta GSK3B Tclin Kinase -3.00390 610.8 955
Segment polarity protein dishevelled homolog DVL-1 DVL1 Tchem Non-IDG -2.11561 188.4 169
Low-density lipoprotein receptor-related protein 6 LRP6 Tbio Non-IDG -2.44778 273.2 424
Catenin beta-1 CTNNB1 Tchem Non-IDG -3.99948 9786.0 3058
Leucine-rich repeat serine/threonine-protein kinase 2 LRRK2 Tchem Kinase -3.07199 1241.4 740
Protein Wnt-2 WNT2 Tbio Non-IDG -2.28986 167.8 174
Proto-oncogene Wnt-3 WNT3 Tchem Non-IDG -2.03358 99.5 291