Development Level

Tbio 18 | 11,445
Tdark 4 | 6,588
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, complete... 7 | 979
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal neural tube morpholog... 1 | 12
decreased bone mineral density 1 | 126
decreased circulating glucose ... 1 | 126
decreased grip strength 1 | 116
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased neutrophil cell numb... 1 | 42
decreased vertical activity 1 | 208
enlarged heart 1 | 210
hypoactivity 1 | 132
impaired righting response 1 | 26
increased circulating HDL chol... 1 | 80
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased fasted circulating g... 1 | 76
increased total body fat amoun... 1 | 134
thrombocytosis 1 | 27

Disease

ovarian cancer 18 | 8,520
glioblastoma 10 | 5,792
lung cancer 10 | 4,740
Carcinoma 9 | 11,493
Conductive hearing loss 9 | 123
Intellectual disability 9 | 1,016
diabetes mellitus 9 | 1,728
group 3 medulloblastoma 9 | 4,104
osteosarcoma 9 | 7,950
psoriasis 9 | 6,694
Dull intelligence 8 | 645
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Poor school performance 8 | 645
atypical teratoid / rhabdoid tumor 8 | 5,112
ependymoma 8 | 4,679
malignant mesothelioma 8 | 3,232
medulloblastoma, large-cell 8 | 6,241
Anteverted nostril 7 | 191
Multiple myeloma 7 | 1,332
oligodendroglioma 7 | 2,850
Abnormality of retinal pigmentation 6 | 111
Abnormality of the retinal vasculature 6 | 59
Atypical scarring of skin 6 | 62
Blind Vision 6 | 111
Blindness, Legal 6 | 110
Broad flat nasal bridge 6 | 236
Cataract 6 | 297
Congenital anomaly of testis 6 | 52
Congenital hypoplasia of penis 6 | 176
Electroretinogram abnormal 6 | 95
Glaucoma 6 | 239
Hyperinsulinism 6 | 133
Hypogonadism 6 | 173
Keratoconus 6 | 113
Lens Opacities 6 | 231
Nasal bridge wide 6 | 236
Night blindness, progressive 6 | 51
Nystagmus 6 | 317
Obesity 6 | 678
Ophthalmoplegia 6 | 106
Optic Atrophy 6 | 242
Photodysphoria 6 | 121
Photophobia 6 | 121
Retinal pigment epithelial abnormality 6 | 111
Retinitis Pigmentosa 6 | 226
Sensorineural Hearing Loss (disorder) 6 | 284
Difficulties with night vision 5 | 87
Night Blindness 5 | 101
adult high grade glioma 5 | 3,801
acute myeloid leukemia 4 | 783
astrocytoma 4 | 1,146
Autosomal recessive predisposition 3 | 1,442
Cleft Palate 3 | 271
Hypoplastic mandible condyle 3 | 275
Kidney cancer 3 | 2,613
Mandibular hypoplasia 3 | 275
Micrognathism 3 | 275
Retinitis pigmentosa 11 3 | 59
Retinitis pigmentosa 13 3 | 11
Uranostaphyloschisis 3 | 167
dermatomyositis 3 | 966
primitive neuroectodermal tumor 3 | 3,035
Absent auditory canals 2 | 23
Absent external auditory canals 2 | 23
Atresia of the external auditory canal 2 | 23
Atretic auditory canal 2 | 23
Atrial Septal Defects 2 | 85
Choanal Atresia 2 | 42
Congenital Epicanthus 2 | 177
Epilepsy 2 | 792
Feeding difficulties 2 | 127
Feeding difficulties in infancy 2 | 175
Gaucher disease type 1 2 | 180
Hypotrophic malar bone 2 | 129
Low Vision 2 | 174
Low set ears 2 | 181
Malar flattening 2 | 129
Nager acrofacial dysostosis 2 | 21
Pallor of optic disc 2 | 39
Preauricular skin tag 2 | 19
Retinal Degeneration 2 | 106
Retinitis pigmentosa 18 2 | 16
Short stature 2 | 531
Skin tag on the posterior cheek 2 | 19
Small head 2 | 374
Treacher Collins syndrome 2 | 27
Ventricular Septal Defects 2 | 119
Visual Impairment 2 | 174
Waldenstrons macroglobulinemia 2 | 765
astrocytic glioma 2 | 2,597
breast carcinoma 2 | 1,638
glioblastoma multiforme 2 | 142
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
non primary Sjogren syndrome sicca 2 | 891
pituitary cancer 2 | 1,972
sonic hedgehog group medulloblastoma 2 | 467
subependymal giant cell astrocytoma 2 | 2,287

Tissue

Blood and immune system 23 | 16,909
Cardiovascular System 23 | 15,192
Digestive Tract 23 | 17,369
Endocrine System 23 | 18,159
Female tissues 23 | 17,400
Liver and Pancreas 23 | 16,750
Male tissues 23 | 17,142
Nervous System 23 | 16,725
Respiratory system 23 | 16,393
Skin and soft tissues 23 | 17,230
Urinary Tract 23 | 16,678

Target Family

Non-IDG 21 | 12,091
Enzyme 2 | 4,145

GO Component

U4-U6 x U5 tri-snRNP complex 23 | 23
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
U6 snRNA-associated Sm-like protein LSm2 LSM2 Tbio Non-IDG -1.40226 23.0 121
Pre-mRNA-splicing factor 18 PRPF18 Tbio Non-IDG -1.36183 19.8 84
U6 snRNA-associated Sm-like protein LSm8 LSM8 Tdark Non-IDG -0.82004 6.23 34
Peptidyl-prolyl cis-trans isomerase H PPIH Tbio Enzyme -1.36230 23.3 88
Pre-mRNA-processing-splicing factor 8 PRPF8 Tbio Non-IDG -1.73166 55.2 78
Small nuclear ribonucleoprotein Sm D2 SNRPD2 Tbio Non-IDG -1.68245 44.9 118
U4/U6.U5 tri-snRNP-associated protein 1 SART1 Tbio Non-IDG -1.82978 70.5 140
U5 small nuclear ribonucleoprotein 200 kDa helicase SNRNP200 Tbio Enzyme -1.71387 54.4 45
116 kDa U5 small nuclear ribonucleoprotein component EFTUD2 Tbio Non-IDG -1.57287 38.6 177
Thioredoxin-like protein 4A TXNL4A Tbio Non-IDG -1.13546 11.1 28