Development Level

Tbio 38 | 11,651
Tdark 6 | 6,593

IMPC Phenotype

preweaning lethality, complete... 7 | 979
decreased total body fat amoun... 4 | 207
decreased circulating insulin ... 3 | 76
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
increased lean body mass 3 | 172
increased total body fat amoun... 3 | 134
preweaning lethality, incomple... 3 | 499
abnormal behavior 2 | 298
decreased circulating glucose ... 2 | 126
increased bone mineral content 2 | 108
increased bone mineral density 2 | 72
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal response to new envir... 1 | 10
abnormal response to tactile s... 1 | 17
abnormal sleep behavior 1 | 70
abnormal testis morphology 1 | 43
abnormal thymus morphology 1 | 7
alopecia 1 | 1
decreased IgE level 1 | 6
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating alkaline... 1 | 46
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating lactate ... 1 | 3
decreased fasted circulating g... 1 | 65
decreased large unstained cell... 1 | 11
decreased lean body mass 1 | 135
embryonic growth retardation 1 | 106
enlarged epididymis 1 | 31
increased circulating glucose ... 1 | 24
increased circulating serum al... 1 | 22
increased erythrocyte cell num... 1 | 39
increased exploration in new e... 1 | 8
increased grip strength 1 | 41
increased heart rate 1 | 23
increased heart weight 1 | 62
increased mean corpuscular hem... 1 | 36
limb grasping 1 | 41
long tibia 1 | 25
mammalian phenotype 1 | 17
small thymus 1 | 16
tremors 1 | 39
trunk curl 1 | 16

Disease

ovarian cancer 29 | 8,520
medulloblastoma, large-cell 23 | 6,241
osteosarcoma 21 | 7,950
glioblastoma 18 | 5,792
psoriasis 17 | 6,694
Carcinoma 15 | 11,493
atypical teratoid / rhabdoid tumor 15 | 5,112
ependymoma 15 | 4,679
group 3 medulloblastoma 14 | 4,104
Astrocytoma, Pilocytic 11 | 3,081
Pick disease 11 | 1,894
Hypomyelinating leukodystrophy 6 10 | 26
Tetanus 10 | 68
lung cancer 10 | 4,740
malignant mesothelioma 10 | 3,232
adult high grade glioma 9 | 3,801
astrocytic glioma 9 | 2,597
oligodendroglioma 9 | 2,850
group 4 medulloblastoma 8 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
non-small cell lung cancer 8 | 2,890
tuberculosis 8 | 2,010
Multiple myeloma 7 | 1,332
Schizophrenia 7 | 1,160
invasive ductal carcinoma 7 | 2,951
lung carcinoma 7 | 2,843
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
lung adenocarcinoma 6 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
primitive neuroectodermal tumor 6 | 3,035
Alzheimer's disease 5 | 658
Vici syndrome 5 | 14
cystic fibrosis 5 | 1,696
dermatomyositis 5 | 966
ductal carcinoma in situ 5 | 1,745
progressive supranuclear palsy 5 | 676
subependymal giant cell astrocytoma 5 | 2,287
Bipolar Disorder 4 | 666
Botulism 4 | 24
astrocytoma 4 | 1,146
gastric cancer 4 | 459
pancreatic cancer 4 | 2,398
pancreatic carcinoma 4 | 562
ulcerative colitis 4 | 1,819
Absent reflex 3 | 92
Absent tendon reflex 3 | 92
Autosomal recessive predisposition 3 | 1,442
Batten disease 3 | 13
Breast cancer 3 | 3,578
Cataract 8 multiple types 3 | 33
Cerebellar Ataxia 3 | 304
Diarrhea 3 | 253
Dysarthria 3 | 192
Epilepsy 3 | 792
Gaucher disease type 1 3 | 180
Reflex, Deep Tendon, Absent 3 | 92
acute myeloid leukemia 3 | 783
acute quadriplegic myopathy 3 | 1,158
adrenocortical carcinoma 3 | 1,428
aldosterone-producing adenoma 3 | 665
colon cancer 3 | 1,478
interstitial cystitis 3 | 2,312
juvenile dermatomyositis 3 | 1,187
non primary Sjogren syndrome sicca 3 | 891
spina bifida 3 | 1,074
Anemia 2 | 365
Attention deficit hyperactivity disorder 2 | 278
Blepharoptosis 2 | 231
Cognitive delay 2 | 608
Colitis 2 | 54
Concave bridge of nose 2 | 195
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Difficulty walking 2 | 28
Down syndrome 2 | 499
Global developmental delay 2 | 608
Heart disease 2 | 306
Hermansky-Pudlak syndrome 2 | 42
Intellectual disability 2 | 1,016
Kidney Failure 2 | 111
Liver Cirrhosis, Experimental 2 | 769
MAJOR AFFECTIVE DISORDER 2 2 | 22
Male infertility 2 | 206
Mental and motor retardation 2 | 608
Multiple Sclerosis 2 | 540
Neurodegenerative disease 2 | 414
Osteoporosis 2 | 363
Pancreatic agenesis 2 | 17
Parkinson's disease 2 | 392
Rheumatoid arthritis 2 | 1,191
Waldenstrons macroglobulinemia 2 | 765
active Crohn's disease 2 | 922
axial spondyloarthropathy 2 | 28
breast carcinoma 2 | 1,638
diabetes mellitus 2 | 1,728
nasopharyngeal carcinoma 2 | 1,058
pediatric high grade glioma 2 | 1,064
pituitary cancer 2 | 1,972
tuberculosis and treatment for 6 months 2 | 409

Tissue

Blood and immune system 44 | 16,909
Digestive Tract 44 | 17,369
Endocrine System 44 | 18,159
Female tissues 44 | 17,400
Liver and Pancreas 44 | 16,750
Male tissues 44 | 17,142
Nervous System 44 | 16,725
Respiratory system 44 | 16,393
Skin and soft tissues 44 | 17,230
Urinary Tract 44 | 16,678
Cardiovascular System 42 | 15,192

Target Family

Non-IDG 44 | 12,091

GO Component

SNARE complex 44 | 44
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Vesicle-associated membrane protein 8 VAMP8 Tbio Non-IDG -1.79654 64.6 107
Syntaxin-12 STX12 Tbio Non-IDG -1.09934 11.4 124
Gamma-soluble NSF attachment protein NAPG Tbio Non-IDG -1.66116 45.2 127
BET1-like protein BET1L Tbio Non-IDG -0.07918 0.87 16
Vesicle-associated membrane protein 2 VAMP2 Tbio Non-IDG -2.53335 323.7 203
Syntaxin-1B STX1B Tbio Non-IDG -1.76579 55.3 27
Vesicle-trafficking protein SEC22c SEC22C Tdark Non-IDG 0.06 0.99 33
Synaptosomal-associated protein 29 SNAP29 Tbio Non-IDG -1.47467 28.0 125
Syntaxin-4 STX4 Tbio Non-IDG -1.95295 84.2 207
Synaptobrevin homolog YKT6 YKT6 Tbio Non-IDG -1.58852 39.0 37