Development Level

Tbio 33 | 10,625
Tdark 12 | 7,003
Tchem 1 | 1,890

IMPC Phenotype

decreased grip strength 3 | 123
increased circulating HDL chol... 3 | 63
increased circulating choleste... 3 | 53
decreased bone mineral content 2 | 157
decreased erythrocyte cell num... 2 | 43
decreased lean body mass 2 | 195
decreased leukocyte cell numbe... 2 | 54
increased mean corpuscular vol... 2 | 91
short tibia 2 | 82
small adrenal glands 2 | 15
abnormal QRS complex 1 | 25
abnormal behavior 1 | 226
abnormal bone structure 1 | 131
abnormal embryo size 1 | 112
abnormal rib morphology 1 | 28
abnormal skin appearance 1 | 8
abnormal vertebral arch morpho... 1 | 9
decreased CD4-positive, alpha ... 1 | 19
decreased CD8-positive, alpha-... 1 | 26
decreased T cell number 1 | 31
decreased body length 1 | 108
decreased bone mineral density 1 | 126
decreased cardiac muscle contr... 1 | 5
decreased cervical vertebrae n... 1 | 12
decreased circulating alanine ... 1 | 53
decreased circulating amylase ... 1 | 24
decreased circulating fructosa... 1 | 31
decreased circulating iron lev... 1 | 25
decreased circulating triglyce... 1 | 83
decreased hematocrit 1 | 25
decreased hemoglobin content 1 | 53
decreased mean corpuscular hem... 1 | 19
decreased neutrophil cell numb... 1 | 37
decreased respiratory quotient 1 | 12
decreased startle reflex 1 | 48
enlarged spleen 1 | 26
hypoactivity 1 | 89
impaired glucose tolerance 1 | 52
increased NK cell number 1 | 19
increased circulating alkaline... 1 | 119
increased circulating bilirubi... 1 | 16
increased circulating glucose ... 1 | 16
increased circulating serum al... 1 | 25
increased effector memory CD4-... 1 | 15
increased effector memory CD8-... 1 | 14
increased grip strength 1 | 83
increased lean body mass 1 | 107
increased lymphocyte cell numb... 1 | 9
increased mean corpuscular hem... 1 | 93
increased mean platelet volume 1 | 19
increased monocyte cell number 1 | 27
increased red blood cell distr... 1 | 21
male infertility 1 | 62
preweaning lethality, complete... 1 | 633
preweaning lethality, incomple... 1 | 260
shortened PQ interval 1 | 6
small thymus 1 | 11
thrombocytosis 1 | 23

Disease

ovarian cancer 27 | 8,491
medulloblastoma, large-cell 25 | 6,234
glioblastoma 23 | 5,572
atypical teratoid / rhabdoid tumor 21 | 4,369
osteosarcoma 18 | 7,933
psoriasis 16 | 6,685
Breast cancer 13 | 3,098
primitive neuroectodermal tumor 12 | 3,031
oligodendroglioma 10 | 2,849
Cancer 9 | 2,346
adult high grade glioma 9 | 2,148
astrocytic glioma 9 | 2,241
pilocytic astrocytoma 9 | 3,086
subependymal giant cell astrocytoma 9 | 2,287
Multiple myeloma 8 | 1,327
ependymoma 8 | 2,514
pediatric high grade glioma 8 | 2,712
group 3 medulloblastoma 7 | 2,254
group 4 medulloblastoma 7 | 1,875
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,988
invasive ductal carcinoma 7 | 2,950
lung cancer 7 | 4,473
malignant mesothelioma 7 | 3,163
medulloblastoma 7 | 1,524
colon cancer 6 | 1,475
interstitial cystitis 6 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,289
posterior fossa group B ependymoma 6 | 1,530
ulcerative colitis 6 | 2,087
Carcinoma 5 | 2,147
acute myeloid leukemia 5 | 785
breast carcinoma 5 | 1,614
lung carcinoma 5 | 2,844
non-small cell lung cancer 5 | 2,798
pituitary cancer 5 | 1,972
primary pancreatic ductal adenocarcinoma 5 | 1,271
Pick disease 4 | 1,893
Rheumatoid Arthritis 4 | 1,170
Waldenstrons macroglobulinemia 4 | 764
cutaneous lupus erythematosus 4 | 1,056
cystic fibrosis 4 | 1,670
dermatomyositis 4 | 966
pancreatic cancer 4 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
posterior fossa group A ependymoma 4 | 1,511
sonic hedgehog group medulloblastoma 4 | 1,482
spina bifida 4 | 1,064
tuberculosis 4 | 1,563
Stevens-Johnson syndrome 3 | 91
adrenocortical carcinoma 3 | 1,427
Atopic dermatitis 2 | 944
Endometrial Neoplasms 2 | 50
Parkinson's disease 2 | 364
Polycystic Ovary Syndrome 2 | 334
Prostatic Neoplasms 2 | 471
astrocytoma 2 | 1,493
atypical teratoid/rhabdoid tumor 2 | 1,095
ductal carcinoma in situ 2 | 1,745
esophageal adenocarcinoma 2 | 737
gastric carcinoma 2 | 832
juvenile dermatomyositis 2 | 1,189
lung adenocarcinoma 2 | 2,714
nasopharyngeal carcinoma 2 | 1,056
non primary Sjogren syndrome sicca 2 | 840
tuberculosis and treatment for 6 months 2 | 686
Adenoid Cystic Carcinoma 1 | 99
Alzheimer's disease 1 | 644
Amblyopia 1 | 24
Bladder Neoplasm 1 | 109
Chronic obstructive pulmonary disease 1 | 147
Cockayne syndrome 1 | 54
Corneal dystrophy 1 | 15
Down syndrome 1 | 548
Endometriosis 1 | 535
Fanconi's anemia 1 | 50
Immune system cancer 1 | 38
Keratitis 1 | 42
Liver carcinoma 1 | 217
Liver neoplasms 1 | 108
Mammary Neoplasms 1 | 410
Mediastinitis 1 | 7
Narcolepsy 1 | 69
Neurodegenerative disease 1 | 383
Omphalocele 1 | 22
Peripheral vascular disease 1 | 90
Prostate cancer 1 | 172
active Crohn's disease 1 | 918
active ulcerative colitis 1 | 477
acute quadriplegic myopathy 1 | 1,157
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 499
estrogen-receptor positive breast cancer 1 | 7
fibroadenoma 1 | 557
glioblastoma multiforme 1 | 347
inflammatory breast cancer 1 | 404
neuronal ceroid lipofuscinosis 5 1 | 2
non-small cell lung carcinoma 1 | 413
pancreatic carcinoma 1 | 567
progressive supranuclear palsy 1 | 674
tuberculosis and treatment for 3 months 1 | 327

Tissue

Blood and immune system 46 | 17,994
Female tissues 46 | 18,646
Liver and Pancreas 46 | 18,135
Male tissues 46 | 17,968
Nervous System 46 | 18,560
Urinary Tract 46 | 18,443
Cardiovascular System 45 | 17,957
Digestive Tract 45 | 18,472
Endocrine System 45 | 18,511
Respiratory system 45 | 17,483
Skin and soft tissues 45 | 18,114

Target Family

Non-IDG 39 | 11,969
Enzyme 7 | 4,146

GO Component

SCF ubiquitin ligase complex 46 | 46
nucleus 5,106 | 5,106
cytoplasm 4,984 | 4,984
plasma membrane 4,118 | 4,118
integral component of membrane 3,679 | 3,679
cytosol 3,264 | 3,264
extracellular exosome 2,757 | 2,757
nucleoplasm 2,716 | 2,716
membrane 1,906 | 1,906
extracellular region 1,493 | 1,493
integral component of plasma m... 1,406 | 1,406
extracellular space 1,304 | 1,304
mitochondrion 1,231 | 1,231
Golgi apparatus 864 | 864
endoplasmic reticulum 859 | 859
endoplasmic reticulum membrane 848 | 848
nucleolus 815 | 815
Golgi membrane 659 | 659
perinuclear region of cytoplas... 611 | 611
cell surface 594 | 594
intracellular 548 | 548
intracellular membrane-bounded... 536 | 536
cell junction 451 | 451
mitochondrial inner membrane 425 | 425
centrosome 409 | 409
focal adhesion 383 | 383
protein complex 355 | 355
cytoskeleton 343 | 343
dendrite 329 | 329
mitochondrial matrix 322 | 322
cell-cell adherens junction 307 | 307
neuronal cell body 303 | 303
microtubule 294 | 294
lysosomal membrane 278 | 278
apical plasma membrane 277 | 277
proteinaceous extracellular ma... 244 | 244
neuron projection 229 | 229
nuclear membrane 218 | 218
early endosome 217 | 217
axon 214 | 214
lysosome 210 | 210
endosome 208 | 208
actin cytoskeleton 205 | 205
external side of plasma membra... 205 | 205
postsynaptic membrane 204 | 204
extracellular matrix 198 | 198
nuclear speck 197 | 197
membrane raft 196 | 196
endoplasmic reticulum lumen 192 | 192
transcription factor complex 184 | 184
endosome membrane 182 | 182
early endosome membrane 180 | 180
basolateral plasma membrane 174 | 174
nuclear chromatin 169 | 169
synapse 166 | 166
cell-cell junction 161 | 161
nuclear envelope 156 | 156
lamellipodium 153 | 153
mitochondrial outer membrane 148 | 148
blood microparticle 147 | 147
myelin sheath 144 | 144
postsynaptic density 144 | 144
cytoplasmic vesicle 143 | 143
microtubule organizing center 137 | 137
cytoplasmic, membrane-bounded ... 132 | 132
ER to Golgi transport vesicle ... 131 | 131
microtubule cytoskeleton 127 | 127
receptor complex 127 | 127
phagocytic vesicle membrane 126 | 126
cytoplasmic vesicle membrane 125 | 125
midbody 125 | 125
trans-Golgi network 124 | 124
cell cortex 119 | 119
cilium 118 | 118
late endosome 116 | 116
spindle 116 | 116
intracellular ribonucleoprotei... 114 | 114
vesicle 112 | 112
Z disc 110 | 110
bicellular tight junction 110 | 110
anchored component of membrane 109 | 109
growth cone 109 | 109
integral component of lumenal ... 108 | 108
late endosome membrane 107 | 107
endomembrane system 106 | 106
centriole 105 | 105
recycling endosome 104 | 104
spindle pole 104 | 104
perikaryon 103 | 103
integral component of endoplas... 101 | 101
intermediate filament 101 | 101
melanosome 101 | 101
chromosome 100 | 100
dendritic spine 99 | 99
ubiquitin ligase complex 99 | 99
peroxisome 98 | 98
nuclear matrix 97 | 97
PML body 94 | 94
Golgi lumen 93 | 93
keratin filament 93 | 93
trans-Golgi network membrane 92 | 92

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
F-box/LRR-repeat protein 3 FBXL3 Tbio Non-IDG -0.94799 9.59 158
F-box/LRR-repeat protein 21 FBXL21 Tdark Non-IDG 0.00000 0
BTB/POZ domain-containing protein 9 BTBD9 Tbio Non-IDG -1.30579 21.1 87
Kelch repeat and BTB domain-containing protein 4 KBTBD4 Tdark Non-IDG 0.60 0.20 49
S-phase kinase-associated protein 1 SKP1 Tbio Enzyme -2.54884 305.8 337
BTB/POZ domain-containing protein 2 BTBD2 Tdark Non-IDG -0.62754 3.78 38
Ankyrin repeat and BTB/POZ domain-containing protein BTBD11 BTBD11 Tdark Non-IDG 0.25 0.49 0
Ubiquitin carboxyl-terminal hydrolase 47 USP47 Tchem Enzyme -0.67298 5.85 100
F-box only protein 6 FBXO6 Tbio Non-IDG -1.13964 13.1 108
BTB/POZ domain-containing protein 6 BTBD6 Tdark Non-IDG -0.07918 1.20 111