Development Level

Tbio 35 | 11,651
Tdark 12 | 6,593
Tchem 1 | 1,388

IMPC Phenotype

increased circulating HDL chol... 3 | 80
increased circulating choleste... 3 | 66
preweaning lethality, complete... 3 | 979
decreased bone mineral content 2 | 151
decreased circulating total pr... 2 | 49
decreased lean body mass 2 | 135
decreased leukocyte cell numbe... 2 | 73
decreased vertical activity 2 | 208
increased blood urea nitrogen ... 2 | 48
increased circulating creatini... 2 | 38
increased circulating serum al... 2 | 22
increased mean corpuscular hem... 2 | 96
male infertility 2 | 123
short tibia 2 | 97
small adrenal glands 2 | 16
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal vertebral arch morpho... 1 | 9
decreased body length 1 | 101
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating creatini... 1 | 39
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased respiratory quotient 1 | 16
decreased startle reflex 1 | 75
enlarged heart 1 | 210
enlarged spleen 1 | 41
female infertility 1 | 60
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating glucose ... 1 | 24
increased circulating total pr... 1 | 28
increased grip strength 1 | 41
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased red blood cell distr... 1 | 34
preweaning lethality, incomple... 1 | 499
shortened PQ interval 1 | 7
small thymus 1 | 16
thrombocytosis 1 | 27

Disease

Carcinoma 32 | 11,493
medulloblastoma, large-cell 27 | 6,241
ovarian cancer 27 | 8,520
glioblastoma 24 | 5,792
atypical teratoid / rhabdoid tumor 23 | 5,112
osteosarcoma 20 | 7,950
psoriasis 17 | 6,694
adult high grade glioma 15 | 3,801
ependymoma 15 | 4,679
Breast cancer 14 | 3,578
group 3 medulloblastoma 12 | 4,104
primitive neuroectodermal tumor 12 | 3,035
astrocytic glioma 10 | 2,597
oligodendroglioma 10 | 2,850
subependymal giant cell astrocytoma 10 | 2,287
Astrocytoma, Pilocytic 9 | 3,081
Cancer 9 | 2,499
Multiple myeloma 9 | 1,332
lung cancer 9 | 4,740
group 4 medulloblastoma 8 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
invasive ductal carcinoma 7 | 2,951
malignant mesothelioma 7 | 3,232
colon cancer 6 | 1,478
interstitial cystitis 6 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
medulloblastoma 6 | 720
non-small cell lung cancer 6 | 2,890
Kidney cancer 5 | 2,613
acute myeloid leukemia 5 | 783
breast carcinoma 5 | 1,638
lung carcinoma 5 | 2,843
pancreatic cancer 5 | 2,398
pituitary cancer 5 | 1,972
primary pancreatic ductal adenocarcinoma 5 | 1,109
tuberculosis 5 | 2,010
ulcerative colitis 5 | 1,819
Pick disease 4 | 1,894
Rheumatoid arthritis 4 | 1,191
Waldenstrons macroglobulinemia 4 | 765
cutaneous lupus erythematosus 4 | 1,057
cystic fibrosis 4 | 1,696
dermatomyositis 4 | 966
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
spina bifida 4 | 1,074
Stevens-Johnson syndrome 3 | 92
adrenocortical carcinoma 3 | 1,428
pediatric high grade glioma 3 | 1,064
posterior fossa group A ependymoma 3 | 468
Atopic dermatitis 2 | 952
Cockayne syndrome 2 | 60
Endometrial Neoplasms 2 | 55
Endometrial cancer 2 | 311
Neuronal ceroid lipofuscinosis 2 2 | 17
Parkinson's disease 2 | 392
Polycystic ovary syndrome 2 | 360
Prostatic Neoplasms 2 | 495
Schizophrenia 2 | 1,160
Split hand-foot malformation 3 2 | 5
Split hand-foot malformation 6 2 | 3
active ulcerative colitis 2 | 764
astrocytoma 2 | 1,146
ductal carcinoma in situ 2 | 1,745
esophageal adenocarcinoma 2 | 737
gastric carcinoma 2 | 807
juvenile dermatomyositis 2 | 1,187
lung adenocarcinoma 2 | 2,716
nasopharyngeal carcinoma 2 | 1,058
non primary Sjogren syndrome sicca 2 | 891
tuberculosis and treatment for 3 months 2 | 179
Adenoid Cystic Carcinoma 1 | 99
Amyotrophic lateral sclerosis 1 | 451
Babinski Reflex 1 | 100
Bladder Neoplasm 1 | 112
Bradykinesia 1 | 34
Breast Neoplasms 1 | 445
Carcinoma, Adenoid Cystic 1 | 99
Congenital clubfoot 1 | 109
Corneal dystrophy 1 | 24
Dysarthria 1 | 192
Dystonia 1 | 164
Dystonic disease 1 | 106
Fanconi anemia 1 | 56
Frontotemporal dementia 1 | 51
Hyperreflexia 1 | 209
Keratitis 1 | 62
Kidney Failure 1 | 111
Liver Cirrhosis, Experimental 1 | 769
Lower limb spasticity 1 | 10
Mammary Neoplasms 1 | 425
Mediastinitis 1 | 7
Narcolepsy 1 | 72
Neurodegenerative disease 1 | 414
Pilocytic astrocytoma 1 | 56
Slow progression 1 | 89
Tremor 1 | 113
Urinary Bladder Neoplasms 1 | 114
Usher syndrome type 1 1 | 10
posterior fossa group B ependymoma 1 | 416

Tissue

Blood and immune system 47 | 16,909
Digestive Tract 47 | 17,369
Endocrine System 47 | 18,159
Female tissues 47 | 17,400
Liver and Pancreas 47 | 16,750
Male tissues 47 | 17,142
Nervous System 47 | 16,725
Respiratory system 47 | 16,393
Skin and soft tissues 47 | 17,230
Urinary Tract 47 | 16,678
Cardiovascular System 46 | 15,192

Target Family

Non-IDG 41 | 12,091
Enzyme 7 | 4,145

GO Component

SCF ubiquitin ligase complex 48 | 48
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
F-box/LRR-repeat protein 7 FBXL7 Tbio Non-IDG -0.80631 6.84 53
F-box/LRR-repeat protein 3 FBXL3 Tbio Non-IDG -0.99438 10.2 174
F-box/LRR-repeat protein 21 FBXL21 Tdark Non-IDG 0.00000 0
F-box only protein 4 FBXO4 Tbio Non-IDG -1.07080 11.1 225
F-box/LRR-repeat protein 5 FBXL5 Tbio Non-IDG -1.25684 20.6 145
F-box/WD repeat-containing protein 11 FBXW11 Tbio Non-IDG -0.75887 5.88 183
F-box only protein 9 FBXO9 Tbio Non-IDG -0.42429 2.33 122
Kelch-like protein 11 KLHL11 Tdark Non-IDG -0.17587 0.58 71
S-phase kinase-associated protein 1 SKP1 Tbio Enzyme -2.57150 310.1 381
F-box and leucine-rich protein 22 FBXL22 Tdark Non-IDG 0.29 0.26 33