Development Level

Tbio 12 | 11,445
Tchem 5 | 1,598
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal embryo size 3 | 220
abnormal heart morphology 2 | 162
decreased circulating insulin ... 2 | 76
embryonic lethality prior to t... 2 | 278
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal craniofacial morpholo... 1 | 33
abnormal embryo turning 1 | 31
abnormal forebrain development 1 | 20
abnormal heart looping 1 | 5
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal pharyngeal arch morph... 1 | 8
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal tibia morphology 1 | 14
anophthalmia 1 | 33
decreased blood urea nitrogen ... 1 | 51
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating magnesiu... 1 | 13
decreased lean body mass 1 | 135
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
impaired glucose tolerance 1 | 75
increased bone mineral content 1 | 108
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating sodium l... 1 | 71
increased grip strength 1 | 41
increased lean body mass 1 | 172
microphthalmia 1 | 26
persistence of hyaloid vascula... 1 | 33
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
small spleen 1 | 19
small testis 1 | 58

Disease

ovarian cancer 13 | 8,520
Carcinoma 11 | 11,493
osteosarcoma 10 | 7,950
psoriasis 10 | 6,694
atypical teratoid / rhabdoid tumor 9 | 5,112
glioblastoma 9 | 5,792
group 3 medulloblastoma 9 | 4,104
medulloblastoma, large-cell 9 | 6,241
primitive neuroectodermal tumor 7 | 3,035
Breast cancer 6 | 3,578
adult high grade glioma 6 | 3,801
ependymoma 6 | 4,679
invasive ductal carcinoma 6 | 2,951
oligodendroglioma 6 | 2,850
lung cancer 5 | 4,740
ductal carcinoma in situ 4 | 1,745
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
Astrocytoma, Pilocytic 3 | 3,081
Cancer 3 | 2,499
Rheumatoid arthritis 3 | 1,191
astrocytoma 3 | 1,146
breast carcinoma 3 | 1,638
group 4 medulloblastoma 3 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
juvenile dermatomyositis 3 | 1,187
lung adenocarcinoma 3 | 2,716
non-small cell lung cancer 3 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis and treatment for 6 months 3 | 409
Disease Progression 2 | 136
Kidney cancer 2 | 2,613
Multiple myeloma 2 | 1,332
astrocytic glioma 2 | 2,597
colon cancer 2 | 1,478
dermatomyositis 2 | 966
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
46 XY gonadal dysgenesis 1 | 10
46, XY Sex Reversal 5 1 | 1
46,Xy Sex Reversal 5 1 | 1
Abnormal cortical bone morphology 1 | 22
Age related macular degeneration 1 | 72
Alzheimer's disease 1 | 658
Autosomal recessive predisposition 1 | 1,442
Brain infarction 1 | 22
Cardiovascular system disease 1 | 246
Collagenous colitis 1 | 2
Conversion disorder 1 | 6
Dilated ventricles (finding) 1 | 121
Early myoclonic encephalopathy 1 | 15
Ectomesenchymoma 1 | 5
Ectopic Tissue 1 | 14
Frontal lobe hypoplasia 1 | 9
Ganglioneuroma 1 | 13
Glioma 1 | 74
HIV Infections 1 | 102
Hereditary spherocytosis type 3 1 | 14
Hyperreflexia 1 | 209
MICROCEPHALY, PRIMARY AUTOSOMAL RECESSIVE, 1 1 | 16
MYELODYSPLASTIC SYNDROME 1 | 53
Mental and motor retardation 1 | 608
Microcephaly 1 | 166
Myelodysplastic Syndromes 1 | 26
Nance-Horan syndrome 1 | 25
Neoplasms 1 | 63
Neoplasms, Germ Cell and Embryonal 1 | 15
Neovascularization, Pathologic 1 | 6
Occult macular dystrophy 1 | 7
Pachygyria 1 | 41
Partial central choroid dystrophy 1 | 11
Pathologic Neovascularization 1 | 6
Photosensitive trichothiodystrophy 1 | 30
Pick disease 1 | 1,894
Severe mental retardation (I.Q. 20-34) 1 | 99
Swyer Syndrome 1 | 8
Thin upper lip vermilion 1 | 67
Unilateral agenesis of kidney 1 | 20
Upward slant of palpebral fissure 1 | 75
Uterine Cervical Neoplasm 1 | 25
Uterine Cervical Neoplasms 1 | 26
Vesico-Ureteral Reflux 1 | 33
Waldenstrons macroglobulinemia 1 | 765
Xeroderma pigmentosum group D 1 | 33
acute myeloid leukemia 1 | 783
acute quadriplegic myopathy 1 | 1,158
aldosterone-producing adenoma 1 | 665
cystic fibrosis 1 | 1,696
diabetes mellitus 1 | 1,728
fascioscapulohumeral muscular dystrophy 1 | 100
interleukin-7 receptor alpha deficiency 1 | 18
lung carcinoma 1 | 2,843
medulloblastoma 1 | 720
non-inflammatory breast cancer 1 | 66
pediatric high grade glioma 1 | 1,064
primary Sjogren syndrome 1 | 735
progressive supranuclear palsy 1 | 676
sarcoidosis 1 | 370
substance-related disorder 1 | 162
tuberculosis 1 | 2,010
ulcerative colitis 1 | 1,819

Tissue

Blood and immune system 19 | 16,909
Cardiovascular System 19 | 15,192
Digestive Tract 19 | 17,369
Endocrine System 19 | 18,159
Female tissues 19 | 17,400
Liver and Pancreas 19 | 16,750
Male tissues 19 | 17,142
Nervous System 19 | 16,725
Respiratory system 19 | 16,393
Skin and soft tissues 19 | 17,230
Urinary Tract 19 | 16,678

Target Family

Non-IDG 10 | 12,091
Epigenetic 6 | 242
Enzyme 2 | 4,145
Transcription Factor 1 | 1,400

GO Component

PcG protein complex 19 | 19
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Polycomb group RING finger protein 1 PCGF1 Tbio Non-IDG -0.99091 11.4 101
Chromobox protein homolog 8 CBX8 Tchem Epigenetic -2.27537 183.4 505
Polycomb group RING finger protein 3 PCGF3 Tdark Non-IDG -0.48328 1.97 115
Chromobox protein homolog 2 CBX2 Tchem Epigenetic -1.37369 24.3 223
Sex comb on midleg-like protein 2 SCML2 Tbio Epigenetic -1.20453 16.3 103
E3 SUMO-protein ligase CBX4 CBX4 Tchem Epigenetic -1.32793 21.9 353
Polyhomeotic-like protein 2 PHC2 Tbio Non-IDG -2.22805 167.4 82
Ubiquitin-associated protein 2-like UBAP2L Tbio Non-IDG -0.98720 11.4 126
Chromobox protein homolog 6 CBX6 Tchem Epigenetic -0.75383 5.29 190
Polycomb group RING finger protein 6 PCGF6 Tbio Non-IDG -0.82680 8.45 112