Development Level

Tbio 69 | 10,625
Tchem 21 | 1,890
Tdark 3 | 7,003
Tclin 1 | 602

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 6 | 633
preweaning lethality, incomple... 5 | 260
increased or absent threshold ... 3 | 128
abnormal bone structure 2 | 131
abnormal maxilla morphology 2 | 16
abnormal snout morphology 2 | 18
abnormal tooth morphology 2 | 24
decreased body length 2 | 108
decreased circulating glucose ... 2 | 121
decreased rib number 2 | 59
embryonic lethality prior to o... 2 | 148
embryonic lethality prior to t... 2 | 187
increased bone mineral content 2 | 92
abnormal behavior 1 | 226
abnormal digit morphology 1 | 13
abnormal epididymis morphology 1 | 31
abnormal heart morphology 1 | 51
abnormal iris morphology 1 | 12
abnormal lens morphology 1 | 73
abnormal placement of pupils 1 | 4
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal skin morphology 1 | 23
abnormal social/conspecific in... 1 | 3
abnormal vitreous body morphol... 1 | 7
decreased CD4-positive, CD25-p... 1 | 24
decreased NK T cell number 1 | 28
decreased blood urea nitrogen ... 1 | 31
decreased bone mineral content 1 | 157
decreased circulating LDL chol... 1 | 37
decreased circulating fructosa... 1 | 31
decreased fasted circulating g... 1 | 49
decreased grip strength 1 | 123
decreased leukocyte cell numbe... 1 | 54
decreased mean corpuscular hem... 1 | 34
decreased respiratory quotient 1 | 12
decreased total body fat amoun... 1 | 186
enlarged epididymis 1 | 27
enlarged heart 1 | 111
hyperactivity 1 | 108
increased body length 1 | 20
increased bone mineral density 1 | 52
increased circulating LDL chol... 1 | 15
increased circulating sodium l... 1 | 71
increased grip strength 1 | 83
increased heart weight 1 | 37
increased kidney weight 1 | 4
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
irregularly shaped pupil 1 | 7
narrow eye opening 1 | 15
oligodactyly 1 | 14
tremors 1 | 34

Disease

ovarian cancer 57 | 8,484
osteosarcoma 56 | 7,933
medulloblastoma, large-cell 45 | 6,234
psoriasis 44 | 6,685
Cancer 43 | 2,346
glioblastoma 42 | 5,572
lung cancer 39 | 4,466
atypical teratoid / rhabdoid tumor 30 | 4,369
malignant mesothelioma 28 | 3,162
Breast cancer 25 | 3,094
primitive neuroectodermal tumor 23 | 3,031
adult high grade glioma 19 | 2,148
intraductal papillary-mucinous neoplasm (IPMN) 19 | 3,289
subependymal giant cell astrocytoma 18 | 2,287
Pick disease 17 | 1,893
Rheumatoid Arthritis 17 | 1,160
Waldenstrons macroglobulinemia 17 | 765
Carcinoma 16 | 2,147
juvenile dermatomyositis 16 | 1,189
non-small cell lung cancer 16 | 2,798
pediatric high grade glioma 16 | 2,712
pituitary cancer 16 | 1,972
ependymoma 15 | 2,514
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,988
oligodendroglioma 15 | 2,849
pancreatic cancer 15 | 2,300
ulcerative colitis 15 | 2,087
Multiple myeloma 14 | 1,327
astrocytic glioma 14 | 2,241
diabetes mellitus 14 | 1,663
pilocytic astrocytoma 14 | 3,086
dermatomyositis 13 | 933
group 3 medulloblastoma 13 | 2,254
medulloblastoma 13 | 1,524
acute quadriplegic myopathy 12 | 1,157
invasive ductal carcinoma 12 | 2,950
group 4 medulloblastoma 11 | 1,875
primary Sjogren syndrome 10 | 789
tuberculosis 10 | 1,557
Amyotrophic Lateral Sclerosis 9 | 431
astrocytoma 9 | 1,493
Intellectual disability 8 | 573
adrenocortical carcinoma 8 | 1,427
breast carcinoma 8 | 1,614
colon cancer 8 | 1,475
lung adenocarcinoma 8 | 2,713
lung carcinoma 8 | 2,844
sonic hedgehog group medulloblastoma 8 | 1,482
Mammary Neoplasms 7 | 410
Neoplastic Syndromes, Hereditary 7 | 48
Nijmegen breakage syndrome 7 | 23
Parkinson's disease 7 | 364
Prostatic Neoplasms 7 | 471
Renal Cell Carcinoma 7 | 199
acute myeloid leukemia 7 | 780
atypical teratoid/rhabdoid tumor 7 | 1,095
cutaneous lupus erythematosus 7 | 1,056
interstitial cystitis 7 | 2,299
posterior fossa group B ependymoma 7 | 1,530
primary pancreatic ductal adenocarcinoma 7 | 1,271
progressive supranuclear palsy 7 | 674
tuberculosis and treatment for 6 months 7 | 686
Ataxia telangiectasia 6 | 31
Bloom syndrome 6 | 30
Hereditary Breast and Ovarian Cancer Syndrome 6 | 14
Pancreatic Neoplasm 6 | 79
aldosterone-producing adenoma 6 | 664
Adenocarcinoma 5 | 115
Alzheimer's disease 5 | 644
Anemia 5 | 252
Atopic dermatitis 5 | 944
Diabetes Mellitus, Non-Insulin-Dependent 5 | 157
Endometriosis 5 | 535
Liver carcinoma 5 | 217
Malignant neoplasm of breast 5 | 63
Malignant neoplasm of prostate 5 | 67
Metabolic syndrome X 5 | 155
Multiple Sclerosis 5 | 498
Neurodegenerative disease 5 | 383
Obesity 5 | 616
Prostate cancer 5 | 172
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 499
cystic fibrosis 5 | 1,665
ductal carcinoma in situ 5 | 1,745
gastric carcinoma 5 | 832
inflammatory breast cancer 5 | 404
non primary Sjogren syndrome sicca 5 | 840
non-small cell lung carcinoma 5 | 413
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
spina bifida 5 | 1,064
Crohn's disease 4 | 304
IGA Glomerulonephritis 4 | 454
Peripheral Neuropathy 4 | 303
Vascular disease 4 | 281
active Crohn's disease 4 | 918
chronic lymphosyte leukemia 4 | 232
nasopharyngeal carcinoma 4 | 1,056
pancreatic carcinoma 4 | 567
posterior fossa group A ependymoma 4 | 1,511

Tissue

Blood and immune system 94 | 17,995
Male tissues 94 | 17,969
Cardiovascular System 93 | 17,958
Female tissues 93 | 18,647
Liver and Pancreas 93 | 18,136
Nervous System 93 | 18,561
Digestive Tract 92 | 18,473
Endocrine System 92 | 18,512
Urinary Tract 91 | 18,444
Respiratory system 90 | 17,484
Skin and soft tissues 90 | 18,115

Target Family

Non-IDG 47 | 11,971
Enzyme 17 | 4,146
Transcription Factor 14 | 1,400
Kinase 11 | 634
Epigenetic 2 | 242
TF/Epigenetic 2 | 38
Nuclear Receptor 1 | 48

GO Component

PML body 94 | 94
nucleus 5,107 | 5,107
cytoplasm 4,985 | 4,985
plasma membrane 4,118 | 4,118
integral component of membrane 3,679 | 3,679
cytosol 3,265 | 3,265
extracellular exosome 2,758 | 2,758
nucleoplasm 2,717 | 2,717
membrane 1,906 | 1,906
extracellular region 1,493 | 1,493
integral component of plasma m... 1,406 | 1,406
extracellular space 1,304 | 1,304
mitochondrion 1,231 | 1,231
Golgi apparatus 864 | 864
endoplasmic reticulum 859 | 859
endoplasmic reticulum membrane 848 | 848
nucleolus 815 | 815
Golgi membrane 659 | 659
perinuclear region of cytoplas... 611 | 611
cell surface 594 | 594
intracellular 548 | 548
intracellular membrane-bounded... 537 | 537
cell junction 451 | 451
mitochondrial inner membrane 425 | 425
centrosome 409 | 409
focal adhesion 383 | 383
protein complex 355 | 355
cytoskeleton 343 | 343
dendrite 329 | 329
mitochondrial matrix 322 | 322
cell-cell adherens junction 307 | 307
neuronal cell body 303 | 303
microtubule 294 | 294
lysosomal membrane 278 | 278
apical plasma membrane 277 | 277
proteinaceous extracellular ma... 244 | 244
neuron projection 229 | 229
nuclear membrane 218 | 218
early endosome 217 | 217
axon 214 | 214
lysosome 210 | 210
endosome 208 | 208
actin cytoskeleton 205 | 205
external side of plasma membra... 205 | 205
postsynaptic membrane 204 | 204
extracellular matrix 198 | 198
nuclear speck 197 | 197
membrane raft 196 | 196
endoplasmic reticulum lumen 192 | 192
transcription factor complex 184 | 184
endosome membrane 182 | 182
early endosome membrane 180 | 180
basolateral plasma membrane 174 | 174
nuclear chromatin 169 | 169
synapse 166 | 166
cell-cell junction 161 | 161
nuclear envelope 156 | 156
lamellipodium 153 | 153
mitochondrial outer membrane 148 | 148
blood microparticle 147 | 147
myelin sheath 144 | 144
postsynaptic density 144 | 144
cytoplasmic vesicle 143 | 143
microtubule organizing center 137 | 137
cytoplasmic, membrane-bounded ... 132 | 132
ER to Golgi transport vesicle ... 131 | 131
microtubule cytoskeleton 127 | 127
receptor complex 127 | 127
phagocytic vesicle membrane 126 | 126
cytoplasmic vesicle membrane 125 | 125
midbody 125 | 125
trans-Golgi network 124 | 124
cell cortex 119 | 119
cilium 118 | 118
late endosome 116 | 116
spindle 116 | 116
intracellular ribonucleoprotei... 114 | 114
vesicle 112 | 112
Z disc 110 | 110
bicellular tight junction 110 | 110
anchored component of membrane 109 | 109
growth cone 109 | 109
integral component of lumenal ... 108 | 108
late endosome membrane 107 | 107
endomembrane system 106 | 106
centriole 105 | 105
recycling endosome 104 | 104
spindle pole 104 | 104
perikaryon 103 | 103
integral component of endoplas... 101 | 101
intermediate filament 101 | 101
melanosome 101 | 101
chromosome 100 | 100
dendritic spine 99 | 99
ubiquitin ligase complex 99 | 99
peroxisome 98 | 98
nuclear matrix 97 | 97
Golgi lumen 93 | 93
keratin filament 93 | 93
trans-Golgi network membrane 92 | 92

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Replication protein A 32 kDa subunit RPA2 Tbio Non-IDG -1.76828 59.7 468
Homeodomain-interacting protein kinase 1 HIPK1 Tbio Kinase -0.62325 4.93 166
Small ubiquitin-related modifier 1 SUMO1 Tbio Non-IDG -2.69547 474.2 685
Ubiquitin carboxyl-terminal hydrolase 7 USP7 Tchem Enzyme -2.17350 165.7 375
Eukaryotic translation initiation factor 3 subunit E EIF3E Tbio Non-IDG -1.39943 28.0 202
Double-strand break repair protein MRE11A MRE11 Tbio Non-IDG -1.95631 90.0 412
RAD52 motif-containing protein 1 RDM1 Tbio Non-IDG -0.84045 6.86 56
WD repeat and FYVE domain-containing protein 3 WDFY3 Tbio Non-IDG -1.21899 18.5 76
NEDD4-binding protein 1 N4BP1 Tdark Non-IDG -0.53701 2.75 85
Probable E3 ubiquitin-protein ligase TRIM8 TRIM8 Tbio Enzyme -1.38628 29.5 112