Development Level

Tbio 72 | 11,445
Tdark 8 | 6,588
Tchem 2 | 1,598
Tclin 1 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 7 | 979
preweaning lethality, incomple... 4 | 499
abnormal behavior 3 | 298
abnormal embryo size 3 | 220
decreased grip strength 2 | 116
increased grip strength 2 | 41
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo turning 1 | 31
abnormal lens morphology 1 | 81
abnormal skin coloration 1 | 25
abnormal urinary bladder morph... 1 | 11
abnormal vitreous body morphol... 1 | 10
aorta dilation 1 | 3
cataract 1 | 92
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased heart left ventricle... 1 | 28
decreased hematocrit 1 | 46
decreased mature B cell number 1 | 7
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
female infertility 1 | 60
hyperactivity 1 | 148
increased body length 1 | 32
increased bone mineral content 1 | 108
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased or absent threshold ... 1 | 101
male infertility 1 | 123
pallor 1 | 34
small testis 1 | 58
thin ventricular wall 1 | 24
thrombocytopenia 1 | 56

Disease

osteosarcoma 51 | 7,950
ovarian cancer 46 | 8,520
Carcinoma 45 | 11,493
atypical teratoid / rhabdoid tumor 34 | 5,112
glioblastoma 28 | 5,792
lung cancer 27 | 4,740
medulloblastoma, large-cell 27 | 6,241
psoriasis 25 | 6,694
group 3 medulloblastoma 22 | 4,104
ependymoma 20 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
primitive neuroectodermal tumor 18 | 3,035
Breast cancer 16 | 3,578
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
Kidney cancer 15 | 2,613
malignant mesothelioma 15 | 3,232
oligodendroglioma 14 | 2,850
Pick disease 13 | 1,894
adult high grade glioma 12 | 3,801
group 4 medulloblastoma 12 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
pancreatic cancer 12 | 2,398
subependymal giant cell astrocytoma 12 | 2,287
astrocytic glioma 11 | 2,597
juvenile dermatomyositis 11 | 1,187
lung adenocarcinoma 11 | 2,716
Astrocytoma, Pilocytic 10 | 3,081
Cancer 10 | 2,499
acute quadriplegic myopathy 10 | 1,158
invasive ductal carcinoma 10 | 2,951
lung carcinoma 10 | 2,843
spina bifida 10 | 1,074
Multiple myeloma 9 | 1,332
dermatomyositis 9 | 966
non-small cell lung cancer 9 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
pituitary cancer 9 | 1,972
tuberculosis 9 | 2,010
astrocytoma 8 | 1,146
breast carcinoma 8 | 1,638
Amyotrophic lateral sclerosis 7 | 451
Liver cancer 6 | 604
Waldenstrons macroglobulinemia 6 | 765
adrenocortical carcinoma 6 | 1,428
cutaneous lupus erythematosus 6 | 1,057
cystic fibrosis 6 | 1,696
ductal carcinoma in situ 6 | 1,745
pediatric high grade glioma 6 | 1,064
primary pancreatic ductal adenocarcinoma 6 | 1,109
Atopic dermatitis 5 | 952
Polycystic ovary syndrome 5 | 360
Primary biliary cirrhosis 5 | 51
Rheumatoid arthritis 5 | 1,191
active Crohn's disease 5 | 922
acute myeloid leukemia 5 | 783
aldosterone-producing adenoma 5 | 665
colon cancer 5 | 1,478
medulloblastoma 5 | 720
primary Sjogren syndrome 5 | 735
progressive supranuclear palsy 5 | 676
ulcerative colitis 5 | 1,819
HIV Infections 4 | 102
active ulcerative colitis 4 | 764
diabetes mellitus 4 | 1,728
hepatocellular carcinoma 4 | 547
interstitial cystitis 4 | 2,312
non primary Sjogren syndrome sicca 4 | 891
Acquired immunodeficiency syndrome 3 | 197
Alzheimer's disease 3 | 658
Autosomal recessive predisposition 3 | 1,442
Bipolar Disorder 3 | 666
Infertility 3 | 188
Neoplasm Invasiveness 3 | 161
Neurodegenerative disease 3 | 414
atypical teratoid/rhabdoid tumor 3 | 357
inflammatory breast cancer 3 | 286
nasopharyngeal carcinoma 3 | 1,058
tuberculosis and treatment for 6 months 3 | 409
urothelial carcinoma 3 | 318
Alcoholic Intoxication, Chronic 2 | 289
Depressive disorder 2 | 409
Diarrhea 2 | 253
Down syndrome 2 | 499
Duchenne muscular dystrophy 2 | 601
Highly variable clinical phenotype 2 | 150
Highly variable phenotype and severity 2 | 150
Highly variable phenotype, even within families 2 | 150
Huntington's disease 2 | 76
Male infertility 2 | 206
Mesothelioma, Malignant 2 | 105
Multiple Sclerosis 2 | 540
Phenotypic variability 2 | 150
Schizophrenia 2 | 1,160
Substance-Related Disorders 2 | 115
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
chronic rhinosinusitis 2 | 512
fibroadenoma 2 | 559
pancreatic carcinoma 2 | 562
posterior fossa group B ependymoma 2 | 416
tuberculosis and treatment for 3 months 2 | 179

Tissue

Endocrine System 82 | 18,159
Blood and immune system 81 | 16,909
Female tissues 81 | 17,400
Male tissues 81 | 17,142
Nervous System 81 | 16,725
Respiratory system 81 | 16,393
Digestive Tract 80 | 17,369
Liver and Pancreas 80 | 16,750
Skin and soft tissues 80 | 17,230
Urinary Tract 80 | 16,678
Cardiovascular System 78 | 15,192

Target Family

Non-IDG 61 | 12,091
Enzyme 19 | 4,145
Transcription Factor 2 | 1,400
Kinase 1 | 634

GO Component

P-body 83 | 83
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
U6 snRNA-associated Sm-like protein LSm4 LSM4 Tbio Non-IDG -2.13782 132.0 149
CCR4-NOT transcription complex subunit 1 CNOT1 Tbio Non-IDG -2.10799 119.0 37
Putative helicase MOV-10 MOV10 Tbio Enzyme -1.55297 38.5 121
Protein argonaute-4 AGO4 Tbio Non-IDG -1.42077 23.0 121
U6 snRNA-associated Sm-like protein LSm2 LSM2 Tbio Non-IDG -1.40226 23.0 121
DNA dC->dU-editing enzyme APOBEC-3G APOBEC3G Tbio Non-IDG -2.78510 662.2 477
Calcium-regulated heat-stable protein 1 CARHSP1 Tbio Transcription Factor -0.46078 3.37 54
U6 snRNA-associated Sm-like protein LSm1 LSM1 Tbio Non-IDG -2.01162 106.0 191
Protein LSM14 homolog A LSM14A Tbio Non-IDG -1.13869 16.0 122
Roquin-1 RC3H1 Tbio Non-IDG -1.59779 44.7 106