Development Level

Tbio 7 | 11,445
Tchem 2 | 1,598

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal embryo size 1 | 220
abnormal pericardium morpholog... 1 | 26
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged spleen 1 | 41

Disease

Kabuki syndrome 7 | 27
Carcinoma 6 | 11,493
ovarian cancer 6 | 8,520
Cancer 4 | 2,499
atypical teratoid / rhabdoid tumor 4 | 5,112
glioblastoma 4 | 5,792
medulloblastoma, large-cell 4 | 6,241
osteosarcoma 4 | 7,950
psoriasis 4 | 6,694
Bladder Neoplasm 3 | 112
Breast cancer 3 | 3,578
Esophageal Squamous Cell Carcinoma 3 | 77
Squamous cell carcinoma of esophagus 3 | 77
Urinary Bladder Neoplasms 3 | 114
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
Abnormal dermatoglyphic pattern 2 | 24
Abnormal vertebral bodies 2 | 16
Acquired scoliosis 2 | 281
Adenoid Cystic Carcinoma 2 | 99
Anemia, Hemolytic 2 | 55
Atrial Septal Defects 2 | 85
Autoimmune thrombocytopenia 2 | 22
Birthmark 2 | 35
Blepharoptosis 2 | 231
Blue sclera 2 | 32
Bowed and upward slanting eyebrows 2 | 41
Broad flat nasal bridge 2 | 236
Byzanthine arch palate 2 | 194
Cafe-au-Lait Spots 2 | 37
Carcinoma, Adenoid Cystic 2 | 99
Carcinoma, Transitional Cell 2 | 32
Cerebral atrophy 2 | 178
Conductive hearing loss 2 | 123
Congenital anomaly of spine 2 | 16
Congenital deafness 2 | 185
Congenital hemivertebra 2 | 25
Congenital hypothyroidism 2 | 26
Curvature of spine 2 | 282
Deafness 2 | 198
Decreased size of teeth 2 | 62
Decreased width of tooth 2 | 59
Dental abnormalities 2 | 60
Depressed nasal tip 2 | 11
Dilated ventricles (finding) 2 | 121
Epilepsy 2 | 792
Failure to gain weight 2 | 365
Hearing Loss, Partial 2 | 185
Hip Dislocation, Congenital 2 | 48
Hirsutism 2 | 47
Hypodontia 2 | 81
Hypoplasia of columella 2 | 7
Idiopathic thrombocytopenia 2 | 22
Immune thrombocytopenic purpura 2 | 24
Joint hyperflexibility 2 | 78
Large auricle 2 | 87
Large dysplastic ears 2 | 87
Large pinnae 2 | 87
Large prominent ears 2 | 87
Large protruding ears 2 | 87
Large, floppy ears 2 | 87
Leukemia 2 | 104
Liver cancer 2 | 604
Long eyelashes 2 | 37
Long palpebral fissure 2 | 17
Lymphoid leukemia 2 | 160
Macrotia 2 | 87
Malabsorption 2 | 82
Microdontia (disorder) 2 | 59
Multiple vertebral anomalies 2 | 16
Nasal bridge wide 2 | 236
Obstruction of pelviureteric junction 2 | 8
Pediatric failure to thrive 2 | 365
Pick disease 2 | 1,894
Posteriorly rotated ear 2 | 61
Postnatal growth retardation 2 | 57
Preauricular Fistulae, Congenital 2 | 27
Preauricular dimple 2 | 27
Preauricular sinus 2 | 27
Prominent ear 2 | 56
Protruding ears 2 | 56
Range of joint movement increased 2 | 32
Recurrent aspiration pneumonia 2 | 4
Recurrent infections 2 | 48
Recurrent otitis media 2 | 42
Seizures 2 | 596
Sensorineural Hearing Loss (disorder) 2 | 284
Sezary Syndrome 2 | 27
Short columella 2 | 7
Short fifth finger 2 | 9
Sparse eyebrow 2 | 42
Strabismus 2 | 270
Stricture of anus 2 | 13
Thick, flared eyebrows 2 | 41
Tooth Abnormalities 2 | 69
Ventricular Septal Defects 2 | 119
Widely spaced teeth 2 | 31
adrenocortical carcinoma 2 | 1,428
hearing impairment 2 | 199
pancreatic cancer 2 | 2,398

Tissue

Blood and immune system 9 | 16,909
Cardiovascular System 9 | 15,192
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678

Target Family

Non-IDG 5 | 12,091
Epigenetic 3 | 242
Enzyme 1 | 4,145

GO Component

MLL3-4 complex 9 | 9
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
PAXIP1-associated glutamate-rich protein 1 PAGR1 Tbio Non-IDG -1.03602 8.61 59
Lysine-specific demethylase 6A KDM6A Tchem Epigenetic -2.27999 176.8 119
Retinoblastoma-binding protein 5 RBBP5 Tbio Non-IDG -1.40059 20.2 180
Set1/Ash2 histone methyltransferase complex subunit ASH2 ASH2L Tbio Enzyme -1.56543 33.7 261
Histone-lysine N-methyltransferase 2C KMT2C Tbio Epigenetic -1.87625 76.5 68
Histone-lysine N-methyltransferase 2D KMT2D Tbio Epigenetic -2.08086 118.1 133
Protein dpy-30 homolog DPY30 Tbio Non-IDG -1.33225 21.6 34
PAX-interacting protein 1 PAXIP1 Tbio Non-IDG -1.63612 44.7 79
WD repeat-containing protein 5 WDR5 Tchem Non-IDG -2.10077 115.4 299