Development Level

Tbio 20 | 11,445
Tchem 4 | 1,598
Tdark 4 | 6,588

IMPC Phenotype

preweaning lethality, complete... 6 | 979
embryonic lethality prior to o... 3 | 239
decreased bone mineral density 2 | 126
increased lean body mass 2 | 172
abnormal behavior 1 | 298
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal lens morphology 1 | 81
abnormal pericardium morpholog... 1 | 26
abnormal retinal outer nuclear... 1 | 3
cataract 1 | 92
corneal opacity 1 | 32
decreased body weight 1 | 161
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
decreased total retina thickne... 1 | 17
embryonic growth retardation 1 | 106
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating potassiu... 1 | 29
increased circulating serum al... 1 | 22
increased erythrocyte cell num... 1 | 39
increased fasted circulating g... 1 | 76
increased total body fat amoun... 1 | 134
irregularly shaped pupil 1 | 7
mydriasis 1 | 6
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 22 | 11,493
ovarian cancer 13 | 8,520
osteosarcoma 11 | 7,950
group 3 medulloblastoma 9 | 4,104
Intellectual disability 8 | 1,016
atypical teratoid / rhabdoid tumor 7 | 5,112
psoriasis 7 | 6,694
Kidney cancer 6 | 2,613
malignant mesothelioma 6 | 3,232
medulloblastoma, large-cell 6 | 6,241
Cancer 5 | 2,499
glioblastoma 5 | 5,792
lung cancer 5 | 4,740
Pick disease 4 | 1,894
adult high grade glioma 4 | 3,801
ependymoma 4 | 4,679
Breast cancer 3 | 3,578
Dull intelligence 3 | 645
Kabuki syndrome 3 | 27
Leukemia 3 | 104
Liver cancer 3 | 604
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Multiple myeloma 3 | 1,332
Muscle hypotonia 3 | 571
Poor school performance 3 | 645
astrocytic glioma 3 | 2,597
colon cancer 3 | 1,478
juvenile dermatomyositis 3 | 1,187
oligodendroglioma 3 | 2,850
spina bifida 3 | 1,074
subependymal giant cell astrocytoma 3 | 2,287
Adenoid Cystic Carcinoma 2 | 99
Carcinoma, Adenoid Cystic 2 | 99
Cornelia De Lange Syndrome 1 2 | 3
Failure to gain weight 2 | 365
Koolen de Vries syndrome 2 | 18
Obesity 2 | 678
Parkinson's disease 2 | 392
Pediatric failure to thrive 2 | 365
Rheumatoid arthritis 2 | 1,191
Schizophrenia 2 | 1,160
Short stature 2 | 531
X- linked recessive 2 | 110
acute quadriplegic myopathy 2 | 1,158
astrocytoma 2 | 1,146
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
invasive ductal carcinoma 2 | 2,951
non primary Sjogren syndrome sicca 2 | 891
non-small cell lung cancer 2 | 2,890
pediatric high grade glioma 2 | 1,064
primitive neuroectodermal tumor 2 | 3,035
Abnormality of the retinal vasculature 1 | 59
Acute monocytic leukemia 1 | 13
Adenocarcinoma 1 | 122
Atypical scarring of skin 1 | 62
Autism Spectrum Disorders 1 | 75
Broad-based gait 1 | 19
Bushy eyebrows 1 | 49
Cataract 7 1 | 32
Conductive hearing loss 1 | 123
Congenital anomaly of testis 1 | 52
Craniofacial Abnormalities 1 | 151
Difficulties with night vision 1 | 87
Downward slant of palpebral fissure 1 | 158
Dyslexia 1 | 43
Epidermodysplasia verruciformis 1 | 21
Gastrointestinal Diseases 1 | 12
Gaucher disease type 1 1 | 180
HIV Infections 1 | 102
Heart failure 1 | 162
Hyperinsulinism 1 | 133
Hypertrichosis 1 | 46
Hypoplastic toes 1 | 29
Hypsarrhythmia 1 | 25
Keratoconus 1 | 113
Kleefstra syndrome 1 | 12
Leukemia, Monocytic, Acute 1 | 2
Leukemia, Myelocytic, Acute 1 | 120
Leukemia, Myeloid, Acute 1 | 105
Lymphoid leukemia 1 | 160
Myoclonus 1 | 74
Neonatal abstinence syndrome 1 | 11
Night blindness, progressive 1 | 51
Pheochromocytoma 1 | 24
Photodysphoria 1 | 121
Photophobia 1 | 121
Pitt-Hopkins syndrome 1 | 20
Prader-Willi syndrome 1 | 48
Synophrys 1 | 40
Thin upper lip vermilion 1 | 67
Tremor 1 | 113
Waterhouse-Friderichsen syndrome 1 | 11
Wide nose 1 | 35
Wilms Tumor 1 | 28
Xeroderma pigmentosum group D 1 | 33
hereditary spastic paraplegia 52 1 | 2

Tissue

Blood and immune system 28 | 16,909
Cardiovascular System 28 | 15,192
Digestive Tract 28 | 17,369
Endocrine System 28 | 18,159
Female tissues 28 | 17,400
Liver and Pancreas 28 | 16,750
Male tissues 28 | 17,142
Nervous System 28 | 16,725
Respiratory system 28 | 16,393
Skin and soft tissues 28 | 17,230
Urinary Tract 28 | 16,678

Target Family

Non-IDG 17 | 12,091
Epigenetic 4 | 242
Enzyme 3 | 4,145
Transcription Factor 3 | 1,400
Kinase 1 | 634

GO Component

MLL1 complex 28 | 28
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ribosomal biogenesis protein LAS1L LAS1L Tdark Non-IDG -0.48801 2.91 109
MAX gene-associated protein MGA Tbio Transcription Factor -0.85532 6.90 42
Transcription initiation factor TFIID subunit 6 TAF6 Tbio Non-IDG -1.10650 12.8 159
Transcription initiation factor TFIID subunit 7 TAF7 Tbio Non-IDG -1.16026 13.4 138
Transcription initiation factor TFIID subunit 9 TAF9 Tbio Non-IDG -2.18859 223.1 83
Retinoblastoma-binding protein 5 RBBP5 Tbio Non-IDG -1.40059 20.2 180
Set1/Ash2 histone methyltransferase complex subunit ASH2 ASH2L Tbio Enzyme -1.56543 33.7 261
Transcription initiation factor TFIID subunit 4 TAF4 Tbio Non-IDG -1.42226 27.6 64
Chromatin complexes subunit BAP18 C17orf49 Tdark Non-IDG -0.30821 2.75 66
Sentrin-specific protease 3 SENP3 Tbio Enzyme -1.89884 78.9 191