Development Level

Tbio 76 | 11,445

IMPC Phenotype

abnormal embryo size 1 | 220
abnormal skin morphology 1 | 50
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hydrometra 1 | 53
preweaning lethality, incomple... 1 | 499
prolonged PR interval 1 | 15
small superior vagus ganglion 1 | 74

Disease

Cancer 73 | 2,499
Ankylosing spondylitis 71 | 140
Behcet's disease 70 | 89
diabetes mellitus 58 | 1,728
Acquired immunodeficiency syndrome 57 | 197
Arthritis 57 | 290
Hypersensitivity reaction type II disease 57 | 253
Uveitis 57 | 103
Herpes zoster 56 | 68
Juvenile rheumatoid arthritis 56 | 111
psoriasis 52 | 6,694
Stevens-Johnson syndrome 50 | 92
Human immunodeficiency virus infectious disease 49 | 138
Psoriatic arthritis 49 | 86
dermatomyositis 39 | 966
Carcinoma 37 | 11,493
Rheumatoid arthritis 36 | 1,191
Behcet's syndrome 35 | 50
Congenital adrenal hyperplasia 35 | 73
Dermatitis 35 | 157
Nephritis 35 | 51
Retinal vasculitis 35 | 36
Spondyloarthropathy, Susceptibility To, 1 35 | 35
Synovitis 35 | 78
Takayasu's arteritis 35 | 53
drug-induced hepatitis 35 | 44
Anemia 23 | 365
Hemochromatosis 23 | 54
Kidney disease 22 | 430
Liver disease 22 | 237
Birdshot chorioretinopathy 21 | 23
Hepatitis B 21 | 108
Leprosy 21 | 73
Multiple Sclerosis 21 | 540
Primary immunodeficiency disease 21 | 54
Skin disease 21 | 66
tuberculosis 21 | 2,010
Pre-Eclampsia 15 | 68
Human immunodeficiency virus type 1, susceptibility to 14 | 26
Psoriasis susceptibility 1 14 | 14
glioblastoma 7 | 5,792
lung cancer 7 | 4,740
ovarian cancer 7 | 8,520
subependymal giant cell astrocytoma 7 | 2,287
Astrocytoma, Pilocytic 6 | 3,081
juvenile dermatomyositis 6 | 1,187
Multiple myeloma 5 | 1,332
Schizophrenia 5 | 1,160
cutaneous lupus erythematosus 5 | 1,057
lung carcinoma 5 | 2,843
osteosarcoma 5 | 7,950
adult high grade glioma 4 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
Glioma 3 | 74
astrocytoma 3 | 1,146
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
posterior fossa group A ependymoma 3 | 468
primary Sjogren syndrome 3 | 735
Adverse reaction to drug 2 | 61
Bipolar Disorder 2 | 666
Chemical and Drug Induced Liver Injury 2 | 195
Drug-Related Side Effects and Adverse Reactions 2 | 62
Duchenne muscular dystrophy 2 | 601
Exanthema 2 | 43
Gastrointestinal Hemorrhage 2 | 52
Genetic Predisposition to Disease 2 | 27
HIV Infections 2 | 102
Inflammatory abnormality of the eye 2 | 10
Parapsoriasis 2 | 6
Photodysphoria 2 | 121
Photophobia 2 | 121
Proteinuria 2 | 144
Psychotic Disorders 2 | 151
Weight decreased 2 | 103
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
astrocytic glioma 2 | 2,597
ependymoma 2 | 4,679
inflammatory breast cancer 2 | 286
interstitial cystitis 2 | 2,312
limb girdle muscular dystrophy 2I 2 | 32
lung adenocarcinoma 2 | 2,716
malignant mesothelioma 2 | 3,232
medulloblastoma, large-cell 2 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
Abnormal respiratory patterns 1 | 20
Acne 1 | 52
Amyloidosis 1 | 67
Confusion 1 | 21
Diffuse large B-cell lymphoma 1 | 39
Edema 1 | 81
Heart Diseases 1 | 43
Hematuria 1 | 36
Hemiparesis 1 | 34
Idiopathic pulmonary arterial hypertension 1 | 40
Lymphatic system disease 1 | 15
Macroglobulinemia 1 | 18
Myasthenia gravis 1 | 23
Urinary tract obstruction 1 | 11

Tissue

Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Respiratory system 7 | 16,393
Blood and immune system 6 | 16,909
Cardiovascular System 6 | 15,192
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678

Target Family

Non-IDG 76 | 12,091

GO Component

MHC class I protein complex 76 | 76
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

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