Development Level

Tbio 4 | 11,651

IMPC Phenotype

abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
prenatal lethality prior to he... 1 | 87

Disease

Carcinoma 2 | 11,493
Dermatitis 2 | 157
POLYGLUCOSAN BODY MYOPATHY 1 WITH OR WITHOUT IMMUNODEFICIENCY 2 | 2
ovarian cancer 2 | 8,520
tuberculosis 2 | 2,010
AUTOINFLAMMATION, PANNICULITIS, AND DERMATOSIS SYNDROME 1 | 1
Autosomal recessive predisposition 1 | 1,442
Cardiomegaly 1 | 116
Cardiomyopathy, Dilated 1 | 83
Creatine phosphokinase serum increased 1 | 110
Elevated creatine kinase 1 | 110
Eosinophilia 1 | 28
Failure to gain weight 1 | 365
Glycogen storage disease 1 | 39
Growth delay 1 | 114
Growth failure 1 | 114
Growth retardation 1 | 115
Highly variable severity 1 | 157
Multiple myeloma 1 | 1,332
Myalgia 1 | 54
Otulipenia 1 | 2
Panniculitis 1 | 9
Pediatric failure to thrive 1 | 365
Poor growth 1 | 114
Progressive disorder 1 | 142
Proximal muscle weakness 1 | 47
Proximal neurogenic muscle weakness 1 | 47
Variable expressivity 1 | 157
Very poor growth 1 | 114
Waldenstrons macroglobulinemia 1 | 765
astrocytic glioma 1 | 2,597
dermatomyositis 1 | 966
ependymoma 1 | 4,679
glioblastoma 1 | 5,792
group 3 medulloblastoma 1 | 4,104
interstitial cystitis 1 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
juvenile dermatomyositis 1 | 1,187
non primary Sjogren syndrome sicca 1 | 891
oligodendroglioma 1 | 2,850
osteosarcoma 1 | 7,950
posterior fossa group A ependymoma 1 | 468

Tissue

Blood and immune system 4 | 16,909
Cardiovascular System 4 | 15,192
Digestive Tract 4 | 17,369
Endocrine System 4 | 18,159
Female tissues 4 | 17,400
Liver and Pancreas 4 | 16,750
Male tissues 4 | 17,142
Nervous System 4 | 16,725
Respiratory system 4 | 16,393
Skin and soft tissues 4 | 17,230
Urinary Tract 4 | 16,678

Target Family

Enzyme 2 | 4,145
Non-IDG 2 | 12,091

GO Component

LUBAC complex 4 | 4
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
RanBP-type and C3HC4-type zinc finger-containing protein 1 RBCK1 Tbio Non-IDG -1.58319 39.4 224
Sharpin SHARPIN Tbio Non-IDG -1.34381 25.4 127
E3 ubiquitin-protein ligase RNF31 RNF31 Tbio Enzyme -1.75558 57.3 174
Ubiquitin thioesterase otulin OTULIN Tbio Enzyme -1.03026 11.0 66