Development Level

Tbio 5 | 11,445
Tdark 3 | 6,588

IMPC Phenotype

female infertility 1 | 60
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
male infertility 1 | 123
small superior vagus ganglion 1 | 74
small testis 1 | 58

Disease

Carcinoma 8 | 11,493
osteosarcoma 7 | 7,950
ovarian cancer 6 | 8,520
psoriasis 6 | 6,694
Emery-Dreifuss muscular dystrophy 4 | 23
ependymoma 4 | 4,679
invasive ductal carcinoma 4 | 2,951
lung cancer 4 | 4,740
malignant mesothelioma 4 | 3,232
atypical teratoid / rhabdoid tumor 3 | 5,112
ductal carcinoma in situ 3 | 1,745
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
medulloblastoma, large-cell 3 | 6,241
oligodendroglioma 3 | 2,850
subependymal giant cell astrocytoma 3 | 2,287
Astrocytoma, Pilocytic 2 | 3,081
Autosomal Dominant Emery-Dreifuss Muscular Dystrophy (disorder) 2 | 4
Breast cancer 2 | 3,578
Childhood onset 2 | 38
Creatine phosphokinase serum increased 2 | 110
Elevated creatine kinase 2 | 110
Highly variable clinical phenotype 2 | 150
Highly variable phenotype and severity 2 | 150
Highly variable phenotype, even within families 2 | 150
Kidney cancer 2 | 2,613
Large intestine cancer 2 | 126
Liver cancer 2 | 604
Muscle atrophy, proximal 2 | 11
Muscle biopsy shows dystrophic changes 2 | 39
Muscular Dystrophy, Emery-Dreifuss 2 | 5
Muscular dystrophy 2 | 75
Phenotypic variability 2 | 150
Progeria 2 | 25
Proximal muscle weakness 2 | 47
Proximal neurogenic muscle weakness 2 | 47
adult high grade glioma 2 | 3,801
astrocytic glioma 2 | 2,597
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
fibroadenoma 2 | 559
glioblastoma 2 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung adenocarcinoma 2 | 2,716
lung carcinoma 2 | 2,843
non-small cell lung cancer 2 | 2,890
pancreatic cancer 2 | 2,398
primitive neuroectodermal tumor 2 | 3,035
progressive supranuclear palsy 2 | 676
spina bifida 2 | 1,074
tuberculosis 2 | 2,010
Adult onset 1 | 82
Atopic dermatitis 1 | 952
Atrial Fibrillation 1 | 124
Atrophy of cerebellum 1 | 103
Bipolar Disorder 1 | 666
Breast Neoplasms 1 | 445
Cardiac Arrhythmia 1 | 103
Cardiac conduction abnormalities 1 | 78
Cardiomyopathies 1 | 110
Cerebellar degeneration 1 | 103
Colorectal Neoplasms 1 | 243
Conduction disorder of the heart 1 | 79
DOID:2627 1 | 94
Down syndrome 1 | 499
Duchenne muscular dystrophy 1 | 601
Dysarthria 1 | 192
EKG abnormalities 1 | 78
Electrocardiogram abnormal 1 | 81
Electrocardiogram change 1 | 78
Endometrial cancer 1 | 311
Gait Ataxia 1 | 51
Heart conduction disease 1 | 83
Infratentorial atrophy 1 | 103
Mammary Neoplasms 1 | 425
Melanoma 1 | 711
Neck muscle weakness 1 | 17
Neurodegenerative disease 1 | 414
Nonsyndromic deafness 1 | 142
Pick disease 1 | 1,894
Respiratory Insufficiency 1 | 132
Respiratory function loss 1 | 121
Sensorineural hearing loss 1 | 106
Skin cancer 1 | 469
Slow progression 1 | 89
Substance-Related Disorders 1 | 115
Vascular disease 1 | 319
active ulcerative colitis 1 | 764
acute quadriplegic myopathy 1 | 1,158
adrenocortical carcinoma 1 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 510
chronic rhinosinusitis 1 | 512
cystic fibrosis 1 | 1,696
cystic fibrosis and chronic rhinosinusitis 1 | 214
limb girdle muscular dystrophy 2A 1 | 213
mucosa-associated lymphoid tissue lymphoma 1 | 484
nasopharyngeal carcinoma 1 | 1,058
pancreatic carcinoma 1 | 562
pediatric high grade glioma 1 | 1,064

Tissue

Blood and immune system 8 | 16,909
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Skin and soft tissues 8 | 17,230
Digestive Tract 7 | 17,369
Nervous System 7 | 16,725
Respiratory system 7 | 16,393
Urinary Tract 7 | 16,678
Cardiovascular System 6 | 15,192

Target Family

Non-IDG 8 | 12,091

GO Component

LINC complex 8 | 8
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nesprin-2 SYNE2 Tbio Non-IDG -2.62747 380.6 39
Nesprin-3 SYNE3 Tbio Non-IDG -0.90535 8.77 107
Nesprin-1 SYNE1 Tbio Non-IDG -2.28105 171.4 65
SUN domain-containing protein 3 SUN3 Tdark Non-IDG -1.07555 11.7 31
Protein KASH5 CCDC155 Tdark Non-IDG -0.58600 3.79 39
SUN domain-containing protein 1 SUN1 Tbio Non-IDG -1.74780 53.6 58
SUN domain-containing protein 2 SUN2 Tbio Non-IDG -1.66260 38.4 114
Nesprin-4 SYNE4 Tdark Non-IDG -0.42597 3.86 70