Development Level

Tbio 552 | 11,651
Tdark 63 | 6,593
Tchem 53 | 1,388
Tclin 8 | 612

Collection

RFA-RM-18-021 4 | 328
Kinase: IDG Consortium (Target... 3 | 125
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 38 | 979
preweaning lethality, incomple... 19 | 499
embryonic lethality prior to t... 18 | 278
embryonic lethality prior to o... 15 | 239
decreased total body fat amoun... 13 | 207
increased lean body mass 10 | 172
abnormal bone structure 9 | 187
decreased bone mineral content 9 | 151
enlarged heart 9 | 210
increased bone mineral content 9 | 108
abnormal embryo size 8 | 220
abnormal kidney morphology 8 | 65
decreased vertical activity 8 | 208
abnormal behavior 7 | 298
abnormal eye morphology 7 | 68
abnormal heart morphology 6 | 162
abnormal seminal vesicle morph... 6 | 114
decreased body weight 6 | 161
decreased circulating choleste... 6 | 93
decreased circulating serum al... 6 | 82
decreased grip strength 6 | 116
hypoactivity 6 | 132
increased mean corpuscular hem... 6 | 96
increased mean corpuscular vol... 6 | 92
abnormal sleep behavior 5 | 70
cataract 5 | 92
decreased bone mineral density 5 | 126
increased bone mineral density 5 | 72
increased total body fat amoun... 5 | 134
abnormal lens morphology 4 | 81
abnormal retina morphology 4 | 71
abnormal skin morphology 4 | 50
abnormal testis morphology 4 | 43
decreased circulating HDL chol... 4 | 68
decreased circulating LDL chol... 4 | 38
decreased circulating triglyce... 4 | 79
decreased lean body mass 4 | 135
decreased lymphocyte cell numb... 4 | 83
embryonic growth retardation 4 | 106
enlarged kidney 4 | 14
increased circulating alkaline... 4 | 122
increased monocyte cell number 4 | 63
increased startle reflex 4 | 112
male infertility 4 | 123
small testis 4 | 58
abnormal epididymis morphology 3 | 42
abnormal gait 3 | 69
abnormal limb bud morphology 3 | 17
abnormal neural tube closure 3 | 46
abnormal spleen morphology 3 | 55
abnormal vibrissa morphology 3 | 25
decreased blood urea nitrogen ... 3 | 51
decreased body length 3 | 101
decreased caudal vertebrae num... 3 | 53
decreased circulating alanine ... 3 | 47
decreased circulating alkaline... 3 | 46
decreased circulating creatini... 3 | 39
decreased circulating glucose ... 3 | 126
decreased circulating insulin ... 3 | 76
decreased fasted circulating g... 3 | 65
decreased lactate dehydrogenas... 3 | 16
decreased leukocyte cell numbe... 3 | 73
decreased mean corpuscular hem... 3 | 50
edema 3 | 59
enlarged epididymis 3 | 31
hydrometra 3 | 53
hyperactivity 3 | 148
increased blood urea nitrogen ... 3 | 48
increased circulating chloride... 3 | 41
increased circulating serum al... 3 | 22
increased fasted circulating g... 3 | 76
increased grip strength 3 | 41
increased heart weight 3 | 62
abnormal cranium morphology 2 | 36
abnormal lung morphology 2 | 26
abnormal placenta size 2 | 20
brachydactyly 2 | 19
cardiovascular system phenotyp... 2 | 36
decreased circulating aspartat... 2 | 34
decreased erythrocyte cell num... 2 | 62
decreased hematocrit 2 | 46
decreased hemoglobin content 2 | 68
decreased prepulse inhibition 2 | 82
impaired glucose tolerance 2 | 75
impaired pupillary reflex 2 | 26
improved glucose tolerance 2 | 79
increased body weight 2 | 25
increased circulating triglyce... 2 | 42
increased exploration in new e... 2 | 8
increased mean platelet volume 2 | 45
increased red blood cell distr... 2 | 34
limb grasping 2 | 41
pale yolk sac 2 | 25
pallor 2 | 34
persistence of hyaloid vascula... 2 | 33
prenatal lethality 2 | 28
short tibia 2 | 97
small superior vagus ganglion 2 | 74
thrombocytosis 2 | 27
tremors 2 | 39

Disease

Carcinoma 420 | 11,493
ovarian cancer 358 | 8,520
osteosarcoma 302 | 7,950
psoriasis 267 | 6,694
glioblastoma 251 | 5,792
medulloblastoma, large-cell 236 | 6,241
atypical teratoid / rhabdoid tumor 207 | 5,112
ependymoma 184 | 4,679
lung cancer 179 | 4,740
Cancer 149 | 2,499
intraductal papillary-mucinous adenoma (IPMA) 147 | 2,955
Astrocytoma, Pilocytic 146 | 3,081
adult high grade glioma 144 | 3,801
Breast cancer 143 | 3,578
intraductal papillary-mucinous carcinoma (IPMC) 140 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 132 | 3,291
lung carcinoma 128 | 2,843
diabetes mellitus 126 | 1,728
invasive ductal carcinoma 125 | 2,951
malignant mesothelioma 119 | 3,232
tuberculosis 109 | 2,010
Rheumatoid arthritis 108 | 1,191
pancreatic cancer 107 | 2,398
group 3 medulloblastoma 104 | 4,104
group 4 medulloblastoma 103 | 1,855
lung adenocarcinoma 103 | 2,716
non-small cell lung cancer 102 | 2,890
astrocytic glioma 101 | 2,597
oligodendroglioma 101 | 2,850
Kidney cancer 100 | 2,613
primitive neuroectodermal tumor 97 | 3,035
pancreatic ductal adenocarcinoma liver metastasis 94 | 1,962
pituitary cancer 92 | 1,972
interstitial cystitis 91 | 2,312
subependymal giant cell astrocytoma 81 | 2,287
dermatomyositis 76 | 966
Pick disease 75 | 1,894
Hypersensitivity reaction type II disease 73 | 253
Ankylosing spondylitis 72 | 140
Behcet's disease 70 | 89
Multiple myeloma 67 | 1,332
ulcerative colitis 67 | 1,819
Arthritis 66 | 290
cystic fibrosis 66 | 1,696
Autosomal recessive predisposition 64 | 1,442
Juvenile rheumatoid arthritis 64 | 111
breast carcinoma 64 | 1,638
ductal carcinoma in situ 62 | 1,745
juvenile dermatomyositis 61 | 1,187
Acquired immunodeficiency syndrome 60 | 197
Uveitis 60 | 103
Herpes zoster 56 | 68
active Crohn's disease 56 | 922
Human immunodeficiency virus infectious disease 54 | 138
Psoriatic arthritis 54 | 86
Stevens-Johnson syndrome 52 | 92
astrocytoma 52 | 1,146
pediatric high grade glioma 47 | 1,064
Multiple Sclerosis 46 | 540
primary pancreatic ductal adenocarcinoma 46 | 1,109
Schizophrenia 45 | 1,160
adrenocortical carcinoma 45 | 1,428
spina bifida 45 | 1,074
acute quadriplegic myopathy 44 | 1,158
Intellectual disability 42 | 1,016
colon cancer 42 | 1,478
non primary Sjogren syndrome sicca 41 | 891
active ulcerative colitis 40 | 764
Liver disease 39 | 237
primary Sjogren syndrome 39 | 735
Dermatitis 38 | 157
cutaneous lupus erythematosus 37 | 1,057
pancreatic carcinoma 37 | 562
Behcet's syndrome 36 | 50
drug-induced hepatitis 36 | 44
Congenital adrenal hyperplasia 35 | 73
Epilepsy 35 | 792
Nephritis 35 | 51
Retinal vasculitis 35 | 36
Spondyloarthropathy, Susceptibility To, 1 35 | 35
Synovitis 35 | 78
Takayasu's arteritis 35 | 53
aldosterone-producing adenoma 35 | 665
Anemia 34 | 365
Kidney disease 34 | 430
gastric carcinoma 33 | 807
Muscle hypotonia 32 | 571
esophageal adenocarcinoma 31 | 737
nasopharyngeal carcinoma 31 | 1,058
Alzheimer's disease 30 | 658
Hepatitis B 30 | 108
Waldenstrons macroglobulinemia 30 | 765
hepatocellular carcinoma 30 | 547
Liver Cirrhosis, Experimental 28 | 769
Seizures 28 | 596
acute myeloid leukemia 28 | 783
Down syndrome 27 | 499
sarcoidosis 26 | 370
Low intelligence 25 | 645
Mental Retardation 25 | 645

Tissue

Endocrine System 583 | 18,159
Digestive Tract 580 | 17,369
Female tissues 578 | 17,400
Nervous System 573 | 16,725
Blood and immune system 572 | 16,909
Male tissues 572 | 17,142
Skin and soft tissues 572 | 17,230
Liver and Pancreas 571 | 16,750
Urinary Tract 569 | 16,678
Respiratory system 565 | 16,393
Cardiovascular System 538 | 15,192

Target Family

Non-IDG 356 | 12,091
Enzyme 262 | 4,145
Transporter 24 | 473
Kinase 13 | 634
Transcription Factor 11 | 1,400
Ion Channel 6 | 344
GPCR 4 | 408

GO Component

Golgi membrane 676 | 676
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Epithelial membrane protein 2 EMP2 Tbio Non-IDG -2.30856 210.6 116
Atlastin-1 ATL1 Tbio Non-IDG -2.07795 119.7 164
Beta-1,3-galactosyltransferase 1 B3GALT1 Tbio Enzyme -0.68296 3.85 66
Sphingomyelin phosphodiesterase 4 SMPD4 Tbio Enzyme -0.89678 7.05 66
Trafficking protein particle complex subunit 2-like protein TRAPPC2L Tdark Non-IDG -0.18066 0.74 35
HLA class I histocompatibility antigen, A-25 alpha chain HLA-A Tbio Non-IDG -2.41667 4123.8 0
HLA class I histocompatibility antigen, B-51 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 0
ADP-ribosylation factor GTPase-activating protein 2 ARFGAP2 Tbio Enzyme -0.97596 10.1 144
Protein wntless homolog WLS Tbio Non-IDG -2.50699 316.3 71
Polypeptide N-acetylgalactosaminyltransferase 3 GALNT3 Tbio Enzyme -2.80894 644.1 124