Development Level

Tbio 502 | 10,625
Tdark 80 | 7,003
Tchem 70 | 1,890
Tclin 7 | 602

Collection

Eligible Kinase Proteins 3 | 134
Eligible Ion Channel Proteins 1 | 117

IMPC Term

preweaning lethality, complete... 25 | 633
embryonic lethality prior to t... 11 | 187
decreased total body fat amoun... 9 | 186
decreased bone mineral content 8 | 157
decreased circulating triglyce... 7 | 83
decreased bone mineral density 6 | 126
decreased circulating HDL chol... 6 | 77
decreased circulating alanine ... 6 | 53
decreased circulating choleste... 6 | 85
decreased lean body mass 6 | 195
embryonic lethality prior to o... 6 | 148
hypoactivity 6 | 89
increased bone mineral content 6 | 92
preweaning lethality, incomple... 6 | 260
abnormal behavior 5 | 226
abnormal retina morphology 5 | 100
decreased body weight 5 | 174
decreased grip strength 5 | 123
enlarged heart 5 | 111
increased mean corpuscular hem... 5 | 93
increased mean corpuscular vol... 5 | 91
abnormal bone structure 4 | 131
abnormal testis morphology 4 | 30
decreased body length 4 | 108
decreased circulating LDL chol... 4 | 37
decreased circulating serum al... 4 | 79
increased lean body mass 4 | 107
male infertility 4 | 62
abnormal QRS complex 3 | 25
abnormal embryo size 3 | 112
abnormal eye morphology 3 | 38
abnormal limb bud morphology 3 | 15
cardiovascular system phenotyp... 3 | 35
decreased CD8-positive, alpha-... 3 | 26
decreased T cell number 3 | 31
decreased caudal vertebrae num... 3 | 49
decreased circulating glucose ... 3 | 121
decreased fasted circulating g... 3 | 49
decreased lactate dehydrogenas... 3 | 14
decreased prepulse inhibition 3 | 52
decreased rib number 3 | 59
hydrops fetalis 3 | 22
increased blood urea nitrogen ... 3 | 44
increased body weight 3 | 42
increased bone mineral density 3 | 52
increased fasted circulating g... 3 | 68
small testis 3 | 37
straub tail 3 | 26
abnormal epididymis morphology 2 | 31
abnormal gait 2 | 51
abnormal heart morphology 2 | 51
abnormal kidney morphology 2 | 30
abnormal lens morphology 2 | 73
abnormal limb morphology 2 | 7
abnormal retinal pigmentation 2 | 61
abnormal skin morphology 2 | 23
abnormal sleep behavior 2 | 63
abnormal tail morphology 2 | 17
abnormal vibrissa morphology 2 | 17
absent vibrissae 2 | 14
decreased KLRG1-positive NK ce... 2 | 9
decreased NK T cell number 2 | 28
decreased NK cell number 2 | 16
decreased blood urea nitrogen ... 2 | 31
decreased circulating alkaline... 2 | 41
decreased circulating aspartat... 2 | 27
decreased circulating creatini... 2 | 31
decreased circulating glycerol... 2 | 19
decreased circulating insulin ... 2 | 75
decreased eosinophil cell numb... 2 | 41
decreased heart weight 2 | 44
decreased lumbar vertebrae num... 2 | 62
decreased mean corpuscular hem... 2 | 34
decreased vertical activity 2 | 22
enlarged epididymis 2 | 27
hemorrhage 2 | 12
increased CD5-positive Ly6C-po... 2 | 4
increased Ly6C high monocyte n... 2 | 12
increased circulating alkaline... 2 | 119
increased circulating chloride... 2 | 43
increased circulating glycerol... 2 | 11
increased circulating serum al... 2 | 25
increased exploration in new e... 2 | 56
increased mean corpuscular hem... 2 | 25
increased red blood cell distr... 2 | 21
increased sacral vertebrae num... 2 | 62
increased vertical activity 2 | 18
short tibia 2 | 82
shortened RR interval 2 | 19
thrombocytopenia 2 | 46
thrombocytosis 2 | 23
tremors 2 | 34
abnormal cranium morphology 1 | 32
abnormal locomotor activation 1 | 26
abnormal neural tube closure 1 | 37
abnormal tail movements 1 | 12
decreased circulating magnesiu... 1 | 11
decreased effector memory CD8-... 1 | 24
embryonic growth retardation 1 | 28
increased circulating magnesiu... 1 | 10

Disease

ovarian cancer 345 | 8,484
osteosarcoma 292 | 7,933
psoriasis 259 | 6,685
glioblastoma 236 | 5,572
medulloblastoma, large-cell 228 | 6,234
atypical teratoid / rhabdoid tumor 184 | 4,369
lung cancer 167 | 4,466
Cancer 144 | 2,346
intraductal papillary-mucinous adenoma (IPMA) 142 | 2,956
pilocytic astrocytoma 142 | 3,086
intraductal papillary-mucinous carcinoma (IPMC) 136 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 129 | 3,289
lung carcinoma 126 | 2,844
invasive ductal carcinoma 125 | 2,950
diabetes mellitus 124 | 1,663
Breast cancer 122 | 3,094
malignant mesothelioma 109 | 3,162
lung adenocarcinoma 104 | 2,713
pancreatic cancer 102 | 2,300
Rheumatoid Arthritis 98 | 1,160
non-small cell lung cancer 98 | 2,798
oligodendroglioma 98 | 2,849
pediatric high grade glioma 97 | 2,712
primitive neuroectodermal tumor 94 | 3,031
ependymoma 93 | 2,514
group 4 medulloblastoma 90 | 1,875
adult high grade glioma 89 | 2,148
interstitial cystitis 89 | 2,299
pituitary cancer 88 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 84 | 1,795
subependymal giant cell astrocytoma 81 | 2,287
astrocytic glioma 78 | 2,241
ulcerative colitis 76 | 2,087
Carcinoma 74 | 2,147
Ankylosing spondylitis 72 | 138
Hypersensitivity reaction type II disease 72 | 235
Pick disease 71 | 1,893
astrocytoma 70 | 1,493
posterior fossa group A ependymoma 67 | 1,511
breast carcinoma 65 | 1,614
Multiple myeloma 64 | 1,327
ductal carcinoma in situ 64 | 1,745
tuberculosis 64 | 1,557
Juvenile rheumatoid arthritis 63 | 104
cystic fibrosis 63 | 1,665
Arthritis 62 | 248
Uveitis 59 | 103
Acquired immunodeficiency syndrome 58 | 164
juvenile dermatomyositis 58 | 1,189
Behcet's disease 56 | 74
active Crohn's disease 56 | 918
medulloblastoma 55 | 1,524
Psoriatic arthritis 52 | 83
group 3 medulloblastoma 52 | 2,254
primary pancreatic ductal adenocarcinoma 51 | 1,271
posterior fossa group B ependymoma 48 | 1,530
Multiple Sclerosis 47 | 498
sonic hedgehog group medulloblastoma 44 | 1,482
acute quadriplegic myopathy 43 | 1,157
adrenocortical carcinoma 43 | 1,427
primary Sjogren syndrome 43 | 789
spina bifida 43 | 1,064
colon cancer 41 | 1,475
dermatomyositis 41 | 933
Stevens-Johnson syndrome 39 | 78
Liver disease 38 | 219
cutaneous lupus erythematosus 37 | 1,056
non primary Sjogren syndrome sicca 37 | 840
pancreatic carcinoma 36 | 567
tuberculosis and treatment for 6 months 36 | 686
Congenital adrenal hyperplasia 35 | 74
Retinal vasculitis 35 | 36
Takayasu's arteritis 35 | 52
aldosterone-producing adenoma 35 | 664
gastric carcinoma 35 | 832
atypical teratoid/rhabdoid tumor 33 | 1,095
Kidney disease 32 | 396
Anemia 30 | 252
esophageal adenocarcinoma 30 | 737
hepatocellular carcinoma 30 | 532
nasopharyngeal carcinoma 30 | 1,056
Down syndrome 28 | 548
active ulcerative colitis 28 | 477
acute myeloid leukemia 28 | 780
Alzheimer's disease 27 | 644
Hepatitis B 27 | 103
Waldenstrons macroglobulinemia 27 | 765
Intellectual disability 26 | 573
IGA Glomerulonephritis 25 | 454
Hemochromatosis 24 | 55
Leprosy 24 | 77
Atopic dermatitis 23 | 944
Duchenne muscular dystrophy 23 | 602
Skin disease 23 | 65
Prostatic Neoplasms 22 | 471
gastric cancer 22 | 430
Primary immunodeficiency disease 21 | 52
fibroadenoma 21 | 557
non-small cell lung carcinoma 21 | 413
progressive supranuclear palsy 20 | 674

Tissue

Nervous System 582 | 18,561
Digestive Tract 581 | 18,473
Female tissues 580 | 18,647
Endocrine System 579 | 18,512
Liver and Pancreas 578 | 18,136
Urinary Tract 578 | 18,444
Blood and immune system 577 | 17,995
Cardiovascular System 577 | 17,958
Male tissues 577 | 17,969
Respiratory system 572 | 17,484
Skin and soft tissues 565 | 18,115

Target Family

Non-IDG 349 | 11,971
Enzyme 253 | 4,146
Transporter 25 | 473
Kinase 13 | 634
Transcription Factor 8 | 1,400
Ion Channel 7 | 341
GPCR 4 | 406

GO Component

Golgi membrane 659 | 659
nucleus 5,107 | 5,107
cytoplasm 4,985 | 4,985
plasma membrane 4,118 | 4,118
integral component of membrane 3,679 | 3,679
cytosol 3,265 | 3,265
extracellular exosome 2,758 | 2,758
nucleoplasm 2,717 | 2,717
membrane 1,906 | 1,906
extracellular region 1,493 | 1,493
integral component of plasma m... 1,406 | 1,406
extracellular space 1,304 | 1,304
mitochondrion 1,231 | 1,231
Golgi apparatus 864 | 864
endoplasmic reticulum 859 | 859
endoplasmic reticulum membrane 848 | 848
nucleolus 815 | 815
perinuclear region of cytoplas... 611 | 611
cell surface 594 | 594
intracellular 548 | 548
intracellular membrane-bounded... 537 | 537
cell junction 451 | 451
mitochondrial inner membrane 425 | 425
centrosome 409 | 409
focal adhesion 383 | 383
protein complex 355 | 355
cytoskeleton 343 | 343
dendrite 329 | 329
mitochondrial matrix 322 | 322
cell-cell adherens junction 307 | 307
neuronal cell body 303 | 303
microtubule 294 | 294
lysosomal membrane 278 | 278
apical plasma membrane 277 | 277
proteinaceous extracellular ma... 244 | 244
neuron projection 229 | 229
nuclear membrane 218 | 218
early endosome 217 | 217
axon 214 | 214
lysosome 210 | 210
endosome 208 | 208
actin cytoskeleton 205 | 205
external side of plasma membra... 205 | 205
postsynaptic membrane 204 | 204
extracellular matrix 198 | 198
nuclear speck 197 | 197
membrane raft 196 | 196
endoplasmic reticulum lumen 192 | 192
transcription factor complex 184 | 184
endosome membrane 182 | 182
early endosome membrane 180 | 180
basolateral plasma membrane 174 | 174
nuclear chromatin 169 | 169
synapse 166 | 166
cell-cell junction 161 | 161
nuclear envelope 156 | 156
lamellipodium 153 | 153
mitochondrial outer membrane 148 | 148
blood microparticle 147 | 147
myelin sheath 144 | 144
postsynaptic density 144 | 144
cytoplasmic vesicle 143 | 143
microtubule organizing center 137 | 137
cytoplasmic, membrane-bounded ... 132 | 132
ER to Golgi transport vesicle ... 131 | 131
microtubule cytoskeleton 127 | 127
receptor complex 127 | 127
phagocytic vesicle membrane 126 | 126
cytoplasmic vesicle membrane 125 | 125
midbody 125 | 125
trans-Golgi network 124 | 124
cell cortex 119 | 119
cilium 118 | 118
late endosome 116 | 116
spindle 116 | 116
intracellular ribonucleoprotei... 114 | 114
vesicle 112 | 112
Z disc 110 | 110
bicellular tight junction 110 | 110
anchored component of membrane 109 | 109
growth cone 109 | 109
integral component of lumenal ... 108 | 108
late endosome membrane 107 | 107
endomembrane system 106 | 106
centriole 105 | 105
recycling endosome 104 | 104
spindle pole 104 | 104
perikaryon 103 | 103
integral component of endoplas... 101 | 101
intermediate filament 101 | 101
melanosome 101 | 101
chromosome 100 | 100
dendritic spine 99 | 99
ubiquitin ligase complex 99 | 99
peroxisome 98 | 98
nuclear matrix 97 | 97
PML body 94 | 94
Golgi lumen 93 | 93
keratin filament 93 | 93
trans-Golgi network membrane 92 | 92

This is where graphics are reside..