Development Level

Tbio 55 | 11,445
Tdark 14 | 6,588
Tchem 7 | 1,598

Collection

Ion Channel: IDG Consortium (T... 2 | 99
RFA-RM-18-021 2 | 328

IMPC Phenotype

preweaning lethality, complete... 5 | 979
embryonic lethality prior to t... 4 | 278
abnormal eye morphology 3 | 68
preweaning lethality, incomple... 3 | 499
abnormal embryo size 2 | 220
edema 2 | 59
increased mean corpuscular hem... 2 | 96
abnormal bone structure 1 | 187
abnormal craniofacial morpholo... 1 | 33
abnormal forebrain morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal hindbrain morphology 1 | 10
abnormal kidney morphology 1 | 65
abnormal limb morphology 1 | 13
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal skin condition 1 | 6
abnormal skin morphology 1 | 50
abnormal tail movements 1 | 12
anophthalmia 1 | 33
decreased body length 1 | 101
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating potassiu... 1 | 20
decreased pulmonary respirator... 1 | 5
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
enlarged kidney 1 | 14
impaired glucose tolerance 1 | 75
increased CD8-positive, alpha-... 1 | 1
increased T cell number 1 | 6
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating free fat... 1 | 20
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
male infertility 1 | 123
microphthalmia 1 | 26
pale yolk sac 1 | 25
pallor 1 | 34
polydactyly 1 | 7
short tibia 1 | 97
thick skin 1 | 4
unresponsive to tactile stimul... 1 | 8

Disease

ovarian cancer 47 | 8,520
Carcinoma 44 | 11,493
glioblastoma 31 | 5,792
osteosarcoma 29 | 7,950
psoriasis 29 | 6,694
medulloblastoma, large-cell 25 | 6,241
atypical teratoid / rhabdoid tumor 21 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 20 | 2,989
ependymoma 19 | 4,679
lung cancer 18 | 4,740
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,291
lung adenocarcinoma 14 | 2,716
pancreatic cancer 14 | 2,398
adult high grade glioma 12 | 3,801
Astrocytoma, Pilocytic 11 | 3,081
Multiple myeloma 11 | 1,332
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,962
Breast cancer 10 | 3,578
astrocytoma 10 | 1,146
group 3 medulloblastoma 10 | 4,104
invasive ductal carcinoma 10 | 2,951
group 4 medulloblastoma 9 | 1,855
malignant mesothelioma 9 | 3,232
non-small cell lung cancer 9 | 2,890
pituitary cancer 9 | 1,972
Cancer 8 | 2,499
cystic fibrosis 8 | 1,696
diabetes mellitus 8 | 1,728
pediatric high grade glioma 8 | 1,064
spina bifida 8 | 1,074
tuberculosis 8 | 2,010
active Crohn's disease 7 | 922
interstitial cystitis 7 | 2,312
oligodendroglioma 7 | 2,850
subependymal giant cell astrocytoma 7 | 2,287
ulcerative colitis 7 | 1,819
Amyotrophic lateral sclerosis 6 | 451
breast carcinoma 6 | 1,638
dermatomyositis 6 | 966
esophageal adenocarcinoma 6 | 737
juvenile dermatomyositis 6 | 1,187
non primary Sjogren syndrome sicca 6 | 891
primary pancreatic ductal adenocarcinoma 6 | 1,109
primitive neuroectodermal tumor 6 | 3,035
Alzheimer's disease 5 | 658
Kidney cancer 5 | 2,613
Pick disease 5 | 1,894
Rheumatoid arthritis 5 | 1,191
astrocytic glioma 5 | 2,597
hereditary spastic paraplegia 5 | 318
Autosomal recessive predisposition 4 | 1,442
Intellectual disability 4 | 1,016
Schizophrenia 4 | 1,160
active ulcerative colitis 4 | 764
acute quadriplegic myopathy 4 | 1,158
ductal carcinoma in situ 4 | 1,745
fibroadenoma 4 | 559
lung carcinoma 4 | 2,843
pancreatic carcinoma 4 | 562
Cardiovascular system disease 3 | 246
Cognitive delay 3 | 608
Desbuquois dysplasia 3 | 13
Duchenne muscular dystrophy 3 | 601
Failure to gain weight 3 | 365
Global developmental delay 3 | 608
Liver Cirrhosis, Experimental 3 | 769
Mental and motor retardation 3 | 608
Obesity 3 | 678
Pediatric failure to thrive 3 | 365
Prostatic Neoplasms 3 | 495
Type 2 diabetes mellitus 3 | 272
Waldenstrons macroglobulinemia 3 | 765
acute myeloid leukemia 3 | 783
aldosterone-producing adenoma 3 | 665
atypical teratoid/rhabdoid tumor 3 | 357
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
gastric carcinoma 3 | 807
mucosa-associated lymphoid tissue lymphoma 3 | 484
nasopharyngeal carcinoma 3 | 1,058
primary Sjogren syndrome 3 | 735
Bipolar Disorder 2 | 666
Congenital anomaly of face 2 | 56
Coronary artery disease 2 | 268
Diarrhea 2 | 253
Dysmorphic facies 2 | 46
Lipid metabolism disorder 2 | 114
Multiple Sclerosis 2 | 540
Neuroblastoma 2 | 80
adrenocortical carcinoma 2 | 1,428
chronic rhinosinusitis 2 | 512
colon cancer 2 | 1,478
cutaneous lupus erythematosus 2 | 1,057
facial deformity 2 | 46
hepatocellular carcinoma 2 | 547
medulloblastoma 2 | 720
periodontitis 2 | 293
progressive supranuclear palsy 2 | 676
sonic hedgehog group medulloblastoma 2 | 467
tuberculosis and treatment for 6 months 2 | 409

Tissue

Endocrine System 72 | 18,159
Female tissues 71 | 17,400
Nervous System 71 | 16,725
Digestive Tract 70 | 17,369
Liver and Pancreas 70 | 16,750
Male tissues 70 | 17,142
Blood and immune system 69 | 16,909
Skin and soft tissues 69 | 17,230
Urinary Tract 69 | 16,678
Cardiovascular System 67 | 15,192
Respiratory system 67 | 16,393

Target Family

Enzyme 50 | 4,145
Non-IDG 24 | 12,091
Ion Channel 2 | 344

GO Component

Golgi cisterna membrane 76 | 76
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Chondroitin sulfate synthase 1 CHSY1 Tbio Enzyme -1.69082 48.5 101
Alpha-(1,3)-fucosyltransferase 11 FUT11 Tdark Enzyme -0.02741 1.20 110
Galactose-3-O-sulfotransferase 4 GAL3ST4 Tdark Enzyme -0.48192 3.06 142
Alpha-(1,3)-fucosyltransferase 5 FUT5 Tbio Enzyme -1.52044 31.5 32
Ras-related protein Rab-21 RAB21 Tbio Enzyme -1.33715 23.1 275
Beta-1,4-galactosyltransferase 1 B4GALT1 Tbio Enzyme -2.34454 211.1 130
GTP-binding protein SAR1b SAR1B Tbio Enzyme -1.91051 79.7 184
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 ASAP2 Tbio Non-IDG -1.14527 15.1 71
Histo-blood group ABO system transferase ABO Tbio Enzyme 0.00000 0
Sec1 family domain-containing protein 1 SCFD1 Tbio Non-IDG -1.50460 33.8 170