Development Level

Tbio 52 | 10,625
Tdark 14 | 7,003
Tchem 9 | 1,890

Collection

Eligible Ion Channel Proteins 1 | 117

IMPC Term

embryonic lethality prior to t... 4 | 187
preweaning lethality, complete... 3 | 633
preweaning lethality, incomple... 3 | 260
abnormal lens morphology 2 | 73
increased mean corpuscular hem... 2 | 93
abnormal eye morphology 1 | 38
abnormal heart left ventricle ... 1 | 20
abnormal retinal vasculature m... 1 | 15
abnormal skin condition 1 | 6
abnormal tail movements 1 | 12
decreased NK T cell number 1 | 28
decreased bone mineral content 1 | 157
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating alanine ... 1 | 53
decreased circulating calcium ... 1 | 33
decreased circulating choleste... 1 | 85
decreased circulating free fat... 1 | 39
decreased circulating potassiu... 1 | 17
decreased eosinophil cell numb... 1 | 41
decreased hemoglobin content 1 | 53
decreased lean body mass 1 | 195
embryonic lethality prior to o... 1 | 148
hydrops fetalis 1 | 22
immune system phenotype 1 | 17
impaired glucose tolerance 1 | 52
increased CD8-positive, alpha-... 1 | 11
increased circulating alkaline... 1 | 119
increased circulating free fat... 1 | 17
increased fasted circulating g... 1 | 68
increased prepulse inhibition 1 | 21
male infertility 1 | 62
straub tail 1 | 26
thick ventricular wall 1 | 7

Disease

ovarian cancer 47 | 8,484
glioblastoma 31 | 5,572
osteosarcoma 30 | 7,933
psoriasis 30 | 6,685
medulloblastoma, large-cell 25 | 6,234
intraductal papillary-mucinous adenoma (IPMA) 19 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,988
lung cancer 18 | 4,466
atypical teratoid / rhabdoid tumor 16 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,289
lung adenocarcinoma 15 | 2,713
group 4 medulloblastoma 14 | 1,875
pancreatic cancer 14 | 2,300
Breast cancer 11 | 3,094
pilocytic astrocytoma 11 | 3,086
Multiple myeloma 10 | 1,327
adult high grade glioma 10 | 2,148
astrocytoma 10 | 1,493
ependymoma 10 | 2,514
invasive ductal carcinoma 10 | 2,950
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,795
pediatric high grade glioma 10 | 2,712
malignant mesothelioma 9 | 3,162
non-small cell lung cancer 9 | 2,798
pituitary cancer 9 | 1,972
ulcerative colitis 9 | 2,087
atypical teratoid/rhabdoid tumor 8 | 1,095
cystic fibrosis 8 | 1,665
diabetes mellitus 8 | 1,663
spina bifida 8 | 1,064
Cancer 7 | 2,346
active Crohn's disease 7 | 918
interstitial cystitis 7 | 2,299
oligodendroglioma 7 | 2,849
posterior fossa group A ependymoma 7 | 1,511
primary pancreatic ductal adenocarcinoma 7 | 1,271
subependymal giant cell astrocytoma 7 | 2,287
astrocytic glioma 6 | 2,241
breast carcinoma 6 | 1,614
esophageal adenocarcinoma 6 | 737
juvenile dermatomyositis 6 | 1,189
primitive neuroectodermal tumor 6 | 3,031
tuberculosis 6 | 1,557
Amyotrophic Lateral Sclerosis 5 | 431
Pick disease 5 | 1,893
Rheumatoid Arthritis 5 | 1,160
acute quadriplegic myopathy 5 | 1,157
dermatomyositis 5 | 933
hereditary spastic paraplegia 5 | 313
non primary Sjogren syndrome sicca 5 | 840
pancreatic carcinoma 5 | 567
Alzheimer's disease 4 | 644
IGA Glomerulonephritis 4 | 454
acute myeloid leukemia 4 | 780
ductal carcinoma in situ 4 | 1,745
fibroadenoma 4 | 557
lung carcinoma 4 | 2,844
sonic hedgehog group medulloblastoma 4 | 1,482
tuberculosis and treatment for 6 months 4 | 686
Carcinoma 3 | 2,147
Desbuquois dysplasia 3 | 9
Duchenne muscular dystrophy 3 | 602
Intellectual disability 3 | 573
Prostatic Neoplasms 3 | 471
Waldenstrons macroglobulinemia 3 | 765
aldosterone-producing adenoma 3 | 664
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
gastric carcinoma 3 | 832
group 3 medulloblastoma 3 | 2,254
medulloblastoma 3 | 1,524
mucosa-associated lymphoid tissue lymphoma 3 | 480
nasopharyngeal carcinoma 3 | 1,056
posterior fossa group B ependymoma 3 | 1,530
primary Sjogren syndrome 3 | 789
Barrett's esophagus 2 | 183
COPD 2 | 113
Cardiovascular system disease 2 | 194
Chylomicron retention disease 2 | 11
Coronary artery disease 2 | 240
Craniofacial Abnormalities 2 | 147
Diabetes Mellitus, Non-Insulin-Dependent 2 | 157
Ehlers-Danlos syndrome 2 | 42
Hyperphosphatemia 2 | 32
Lipid metabolism disorder 2 | 102
Liver disease 2 | 219
Neuroblastoma 2 | 78
Obesity 2 | 616
Radioulnar synostosis 2 | 13
Sclerocornea 2 | 16
Type 2 diabetes mellitus 2 | 189
active ulcerative colitis 2 | 477
adrenocortical carcinoma 2 | 1,427
chronic rhinosinusitis 2 | 512
colon cancer 2 | 1,475
cutaneous lupus erythematosus 2 | 1,056
gastric cancer 2 | 430
hepatocellular carcinoma 2 | 532
periodontitis 2 | 269
progressive supranuclear palsy 2 | 674
tuberculosis and treatment for 3 months 2 | 327

Tissue

Digestive Tract 72 | 18,473
Nervous System 72 | 18,561
Blood and immune system 71 | 17,995
Female tissues 71 | 18,647
Male tissues 71 | 17,969
Cardiovascular System 70 | 17,958
Endocrine System 70 | 18,512
Liver and Pancreas 70 | 18,136
Respiratory system 70 | 17,484
Skin and soft tissues 70 | 18,115
Urinary Tract 70 | 18,444

Target Family

Enzyme 50 | 4,146
Non-IDG 24 | 11,971
Ion Channel 1 | 341

GO Component

Golgi cisterna membrane 75 | 75
nucleus 5,107 | 5,107
cytoplasm 4,985 | 4,985
plasma membrane 4,118 | 4,118
integral component of membrane 3,679 | 3,679
cytosol 3,265 | 3,265
extracellular exosome 2,758 | 2,758
nucleoplasm 2,717 | 2,717
membrane 1,906 | 1,906
extracellular region 1,493 | 1,493
integral component of plasma m... 1,406 | 1,406
extracellular space 1,304 | 1,304
mitochondrion 1,231 | 1,231
Golgi apparatus 864 | 864
endoplasmic reticulum 859 | 859
endoplasmic reticulum membrane 848 | 848
nucleolus 815 | 815
Golgi membrane 659 | 659
perinuclear region of cytoplas... 611 | 611
cell surface 594 | 594
intracellular 548 | 548
intracellular membrane-bounded... 537 | 537
cell junction 451 | 451
mitochondrial inner membrane 425 | 425
centrosome 409 | 409
focal adhesion 383 | 383
protein complex 355 | 355
cytoskeleton 343 | 343
dendrite 329 | 329
mitochondrial matrix 322 | 322
cell-cell adherens junction 307 | 307
neuronal cell body 303 | 303
microtubule 294 | 294
lysosomal membrane 278 | 278
apical plasma membrane 277 | 277
proteinaceous extracellular ma... 244 | 244
neuron projection 229 | 229
nuclear membrane 218 | 218
early endosome 217 | 217
axon 214 | 214
lysosome 210 | 210
endosome 208 | 208
actin cytoskeleton 205 | 205
external side of plasma membra... 205 | 205
postsynaptic membrane 204 | 204
extracellular matrix 198 | 198
nuclear speck 197 | 197
membrane raft 196 | 196
endoplasmic reticulum lumen 192 | 192
transcription factor complex 184 | 184
endosome membrane 182 | 182
early endosome membrane 180 | 180
basolateral plasma membrane 174 | 174
nuclear chromatin 169 | 169
synapse 166 | 166
cell-cell junction 161 | 161
nuclear envelope 156 | 156
lamellipodium 153 | 153
mitochondrial outer membrane 148 | 148
blood microparticle 147 | 147
myelin sheath 144 | 144
postsynaptic density 144 | 144
cytoplasmic vesicle 143 | 143
microtubule organizing center 137 | 137
cytoplasmic, membrane-bounded ... 132 | 132
ER to Golgi transport vesicle ... 131 | 131
microtubule cytoskeleton 127 | 127
receptor complex 127 | 127
phagocytic vesicle membrane 126 | 126
cytoplasmic vesicle membrane 125 | 125
midbody 125 | 125
trans-Golgi network 124 | 124
cell cortex 119 | 119
cilium 118 | 118
late endosome 116 | 116
spindle 116 | 116
intracellular ribonucleoprotei... 114 | 114
vesicle 112 | 112
Z disc 110 | 110
bicellular tight junction 110 | 110
anchored component of membrane 109 | 109
growth cone 109 | 109
integral component of lumenal ... 108 | 108
late endosome membrane 107 | 107
endomembrane system 106 | 106
centriole 105 | 105
recycling endosome 104 | 104
spindle pole 104 | 104
perikaryon 103 | 103
integral component of endoplas... 101 | 101
intermediate filament 101 | 101
melanosome 101 | 101
chromosome 100 | 100
dendritic spine 99 | 99
ubiquitin ligase complex 99 | 99
peroxisome 98 | 98
nuclear matrix 97 | 97
PML body 94 | 94
Golgi lumen 93 | 93
keratin filament 93 | 93
trans-Golgi network membrane 92 | 92

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beta-galactoside alpha-2,6-sialyltransferase 1 ST6GAL1 Tchem Enzyme -2.37851 255.2 269
Golgin subfamily A member 8B GOLGA8B Tdark Non-IDG -0.15761 1.62 51
Golgin subfamily A member 2 GOLGA2 Tbio Non-IDG -1.94177 80.5 168
Golgin subfamily A member 3 GOLGA3 Tbio Non-IDG -1.29668 20.3 130
Galactoside 2-alpha-L-fucosyltransferase 2 FUT2 Tbio Enzyme -3.02835 1070.9 91
Alpha-(1,3)-fucosyltransferase 4 FUT4 Tbio Enzyme -3.08185 1189.5 813
E3 ubiquitin-protein ligase HACE1 HACE1 Tbio Enzyme -0.48192 4.63 95
Chondroitin sulfate synthase 2 CHPF Tbio Enzyme -1.26790 15.7 116
Alpha-(1,3)-fucosyltransferase 6 FUT6 Tchem Enzyme -1.78089 56.4 154
Alpha-(1,3)-fucosyltransferase 10 FUT10 Tdark Enzyme -0.18564 1.81 101