Development Level

Tbio 7 | 11,445
Tdark 2 | 6,588

IMPC Phenotype

abnormal whole-body plethysmog... 1 | 4
decreased body weight 1 | 161
decreased circulating amylase ... 1 | 28
decreased circulating triglyce... 1 | 79
hyperactivity 1 | 148
increased mean corpuscular hem... 1 | 36
increased vertical activity 1 | 24
preweaning lethality, complete... 1 | 979
tremors 1 | 39

Disease

Carcinoma 5 | 11,493
malignant mesothelioma 4 | 3,232
osteosarcoma 4 | 7,950
ovarian cancer 4 | 8,520
Autosomal recessive predisposition 2 | 1,442
Breast cancer 2 | 3,578
Liver cancer 2 | 604
invasive ductal carcinoma 2 | 2,951
lung cancer 2 | 4,740
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
psoriasis 2 | 6,694
spina bifida 2 | 1,074
tuberculosis and treatment for 3 months 2 | 179
Abnormality of peripheral nerve conduction 1 | 4
Action Tremor 1 | 22
Autosomal recessive limb-girdle muscular dystrophy type 2C 1 | 2
Babinski Reflex 1 | 100
Baller-Gerold syndrome 1 | 12
Bloom syndrome 1 | 29
Cardiomyopathy 1 | 116
Cardiovascular system disease 1 | 246
Cerebellar Dysmetria 1 | 56
Cerebral atrophy 1 | 178
Cervical vertebral abnormalities 1 | 6
Chorea 1 | 29
Choreatic disease 1 | 52
Claw hand 1 | 26
Congenital Bilateral Cataracts 1 | 50
Congenital Cataracts, Facial Dysmorphism, And Neuropathy 1 | 1
Congenital anomaly of face 1 | 56
Congenital cataract 1 | 50
Congenital cataracts-facial dysmorphism-neuropathy syndrome 1 | 1
Congenital clubfoot 1 | 109
Congenital pes cavus 1 | 88
Decreased motor NCV 1 | 22
Degenerative brain disorder 1 | 100
Dental abnormalities 1 | 60
Distal motor neuropathy 1 | 3
Distortion of face 1 | 46
Down syndrome 1 | 499
Dysmorphic facies 1 | 46
Flexion contracture of proximal interphalangeal joint 1 | 75
Funny looking face 1 | 46
Genu recurvatum 1 | 12
Hyperplasia of malar bones 1 | 4
Hypoglycemia 1 | 152
Hypogonadism, Isolated Hypogonadotropic 1 | 71
Hypogonadotropic hypogonadism 1 | 89
Impaired cognition 1 | 96
Infantile onset 1 | 238
Kyphoscoliosis deformity of spine 1 | 60
Length dependent motor neuropathy 1 | 3
Long eyelashes 1 | 37
Low serum estradiol levels 1 | 22
Mental impairment 1 | 95
Mild Mental Retardation 1 | 70
Motor axonal neuropathy 1 | 3
Motor delay 1 | 147
Myoglobinuria 1 | 15
Neuropathy 1 | 261
No development of motor milestones 1 | 147
Nonsyndromic deafness 1 | 142
Osteoporosis 1 | 363
Paresthesia 1 | 32
Peripheral axonal degeneration 1 | 4
Peripheral demyelination 1 | 16
Peripheral hypomyelination 1 | 7
Peripheral motor neuropathy 1 | 4
Pick disease 1 | 1,894
Polyneuropathy, Motor 1 | 4
Primary hypogonadism 1 | 37
Prominent midface 1 | 4
Rapadilino syndrome 1 | 7
Rhabdomyolysis, acute 1 | 2
Rothmund-Thomson syndrome 1 | 19
Sensorineural hearing loss 1 | 106
Sensorineural hearing loss, bilateral 1 | 18
Strabismus 1 | 270
Substance-Related Disorders 1 | 115
Supratentorial atrophy 1 | 94
Terminal tremor 1 | 20
Tooth Abnormalities 1 | 69
Werner syndrome 1 | 29
adult high grade glioma 1 | 3,801
aldosterone-producing adenoma 1 | 665
astrocytoma 1 | 1,146
cystic fibrosis 1 | 1,696
facial deformity 1 | 46
fibroadenoma 1 | 559
gastric carcinoma 1 | 807
hereditary spastic paraplegia 1 | 318
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,291
lung adenocarcinoma 1 | 2,716
non-small cell lung cancer 1 | 2,890
oligodendroglioma 1 | 2,850
progressive supranuclear palsy 1 | 676
sonic hedgehog group medulloblastoma 1 | 467
tuberculosis 1 | 2,010

Tissue

Blood and immune system 7 | 16,909
Cardiovascular System 7 | 15,192
Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Male tissues 7 | 17,142
Nervous System 7 | 16,725
Respiratory system 7 | 16,393
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678

Target Family

Non-IDG 5 | 12,091
Enzyme 4 | 4,145

GO Component

DNA-directed RNA polymerase II... 9 | 9
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

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