Development Level

Tbio 19 | 11,445
Tdark 6 | 6,588

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal response to tactile s... 1 | 17
abnormal sleep behavior 1 | 70
decreased anxiety-related resp... 1 | 12
decreased basophil cell number 1 | 16
decreased circulating LDL chol... 1 | 38
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating triglyce... 1 | 79
increased circulating chloride... 1 | 41
increased circulating total pr... 1 | 28
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 18 | 11,493
ovarian cancer 17 | 8,520
osteosarcoma 14 | 7,950
group 3 medulloblastoma 10 | 4,104
medulloblastoma, large-cell 10 | 6,241
psoriasis 10 | 6,694
primitive neuroectodermal tumor 9 | 3,035
atypical teratoid / rhabdoid tumor 8 | 5,112
ependymoma 8 | 4,679
glioblastoma 8 | 5,792
lung cancer 8 | 4,740
malignant mesothelioma 8 | 3,232
Breast cancer 7 | 3,578
oligodendroglioma 5 | 2,850
Cockayne syndrome 4 | 60
Hypogonadism 4 | 173
Rheumatoid arthritis 4 | 1,191
acute quadriplegic myopathy 4 | 1,158
adult high grade glioma 4 | 3,801
astrocytic glioma 4 | 2,597
group 4 medulloblastoma 4 | 1,855
hepatocellular carcinoma 4 | 547
Cancer 3 | 2,499
Cryptorchidism 3 | 296
Intellectual disability 3 | 1,016
Xeroderma pigmentosum 3 | 43
cutaneous lupus erythematosus 3 | 1,057
invasive ductal carcinoma 3 | 2,951
non-small cell lung cancer 3 | 2,890
pancreatic cancer 3 | 2,398
pediatric high grade glioma 3 | 1,064
pituitary cancer 3 | 1,972
tuberculosis and treatment for 6 months 3 | 409
Autosomal recessive predisposition 2 | 1,442
Cataract 2 | 297
Congenital hypoplasia of penis 2 | 176
Congenital pes cavus 2 | 88
Dry skin 2 | 75
Dull intelligence 2 | 645
Epilepsy 2 | 792
Freckles 2 | 33
Hyperkyphosis 2 | 111
Kidney cancer 2 | 2,613
Kyphosis deformity of spine 2 | 114
Lens Opacities 2 | 231
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Multiple myeloma 2 | 1,332
Optic Atrophy 2 | 242
Photosensitivity of skin 2 | 51
Poor school performance 2 | 645
Seizures 2 | 596
Sensorineural Hearing Loss (disorder) 2 | 284
Strabismus 2 | 270
Tremor 2 | 113
Xerosis 2 | 75
adrenocortical carcinoma 2 | 1,428
astrocytoma 2 | 1,146
breast carcinoma 2 | 1,638
ductal carcinoma in situ 2 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
juvenile dermatomyositis 2 | 1,187
non primary Sjogren syndrome sicca 2 | 891
pancreatic carcinoma 2 | 562
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
primary pancreatic ductal adenocarcinoma 2 | 1,109
subependymal giant cell astrocytoma 2 | 2,287
Abnormal auditory evoked potential 1 | 7
Acquired flat foot 1 | 72
Angle class 2 malocclusion 1 | 57
Angle class 3 malocclusion 1 | 57
Bowen-Conradi syndrome 1 | 16
Conjunctivitis 1 | 53
Conjunctivitis, recurrent 1 | 37
Conjunctivochalasis 1 | 6
Decreased motor NCV 1 | 22
Decreased size of teeth 1 | 62
Flatfoot 1 | 73
Full lower lip 1 | 64
Gynecomastia 1 | 64
Joint laxity 1 | 54
Linear atrophy 1 | 15
MENTAL RETARDATION, X-LINKED, WITH SHORT STATURE, HYPOGONADISM, AND ABNORMAL GAIT 1 | 1
Malocclusion 1 | 57
Neurofibromatosis 1 | 40
Obesity, Abdominal 1 | 24
Open Bite 1 | 21
Papilloma 1 | 44
Prominent lower lip 1 | 64
Relative macrocephaly 1 | 12
Restless legs syndrome 1 | 27
Sandal gap 1 | 24
Scheuermann's disease 1 | 11
Short hands 1 | 50
Small hand 1 | 36
Spider Veins 1 | 17
Xeroderma pigmentosum group E 1 | 3

Tissue

Blood and immune system 25 | 16,909
Digestive Tract 25 | 17,369
Endocrine System 25 | 18,159
Female tissues 25 | 17,400
Liver and Pancreas 25 | 16,750
Male tissues 25 | 17,142
Nervous System 25 | 16,725
Respiratory system 25 | 16,393
Skin and soft tissues 25 | 17,230
Urinary Tract 25 | 16,678
Cardiovascular System 24 | 15,192

Target Family

Non-IDG 25 | 12,091

GO Component

Cul4-RING E3 ubiquitin ligase ... 25 | 25
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DDB1- and CUL4-associated factor 16 DCAF16 Tdark Non-IDG 0.08 0.54 13
DDB1- and CUL4-associated factor 17 DCAF17 Tbio Non-IDG -1.30334 20.5 25
DDB1- and CUL4-associated factor 13 DCAF13 Tbio Non-IDG -0.63403 3.77 86
DDB1- and CUL4-associated factor 1 DCAF1 Tbio Non-IDG -1.71452 57.7 62
DDB1- and CUL4-associated factor 6 DCAF6 Tbio Non-IDG -1.75141 54.7 104
DET1- and DDB1-associated protein 1 DDA1 Tbio Non-IDG -0.93875 9.33 125
F-box/WD repeat-containing protein 5 FBXW5 Tbio Non-IDG -0.48379 3.50 107
DNA damage-binding protein 1 DDB1 Tbio Non-IDG -2.34719 202.5 353
DDB1- and CUL4-associated factor 8 DCAF8 Tdark Non-IDG -0.70899 4.90 50
Denticleless protein homolog DTL Tbio Non-IDG -1.63065 50.0 160