Development Level

Tdark 36 | 7,003
Tbio 28 | 10,625
Tclin 1 | 602

IMPC Term

decreased grip strength 3 | 123
preweaning lethality, incomple... 3 | 260
decreased bone mineral density 2 | 126
decreased circulating triglyce... 2 | 83
increased circulating chloride... 2 | 43
increased lean body mass 2 | 107
increased or absent threshold ... 2 | 128
abnormal QRS complex 1 | 25
abnormal behavior 1 | 226
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal embryo size 1 | 112
abnormal heart left ventricle ... 1 | 20
abnormal radius morphology 1 | 8
abnormal response to tactile s... 1 | 16
abnormal rib morphology 1 | 28
abnormal skin appearance 1 | 8
abnormal vertebral arch morpho... 1 | 9
decreased B cell number 1 | 30
decreased CD4-positive, CD25-p... 1 | 24
decreased CD4-positive, alpha ... 1 | 19
decreased CD8-positive, naive ... 1 | 5
decreased T-helper cell number 1 | 4
decreased blood urea nitrogen ... 1 | 31
decreased bone mineral content 1 | 157
decreased circulating HDL chol... 1 | 77
decreased circulating chloride... 1 | 32
decreased circulating choleste... 1 | 85
decreased circulating creatini... 1 | 31
decreased circulating glucose ... 1 | 121
decreased circulating insulin ... 1 | 75
decreased circulating iron lev... 1 | 25
decreased effector memory CD8-... 1 | 24
decreased gamma-delta T cell n... 1 | 18
decreased hemoglobin content 1 | 53
decreased lean body mass 1 | 195
decreased leukocyte cell numbe... 1 | 54
decreased mature B cell number 1 | 25
decreased respiratory quotient 1 | 12
decreased total body fat amoun... 1 | 186
increased CD4-positive, CD25-p... 1 | 18
increased CD4-positive, alpha ... 1 | 15
increased KLRG1+ CD4 alpha bet... 1 | 5
increased KLRG1+ CD8 alpha bet... 1 | 2
increased KLRG1-positive CD4-n... 1 | 1
increased KLRG1-positive CD4-p... 1 | 3
increased KLRG1-positive NK ce... 1 | 9
increased KLRG1-positive T-hel... 1 | 2
increased KLRG1-positive gamma... 1 | 2
increased Ly6C low monocyte nu... 1 | 8
increased NK cell number 1 | 19
increased blood urea nitrogen ... 1 | 44
increased bone mineral density 1 | 52
increased cardiac muscle contr... 1 | 5
increased circulating LDL chol... 1 | 15
increased circulating alkaline... 1 | 119
increased circulating glucose ... 1 | 16
increased circulating potassiu... 1 | 31
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 24
increased effector memory CD4-... 1 | 15
increased effector memory CD8-... 1 | 14
increased effector memory T-he... 1 | 5
increased eosinophil cell numb... 1 | 9
increased fasted circulating g... 1 | 68
increased grip strength 1 | 83
increased heart rate 1 | 17
increased mean corpuscular vol... 1 | 91
increased memory CD4-positive,... 1 | 3
increased memory-marker CD4-ne... 1 | 1
increased monocyte cell number 1 | 27
increased myeloid cell number 1 | 2
increased neutrophil cell numb... 1 | 15
increased prepulse inhibition 1 | 21
increased rib number 1 | 41
preweaning lethality, complete... 1 | 633
small adrenal glands 1 | 15
small thymus 1 | 11

Disease

ovarian cancer 33 | 8,484
medulloblastoma, large-cell 32 | 6,234
osteosarcoma 28 | 7,933
glioblastoma 25 | 5,572
atypical teratoid / rhabdoid tumor 22 | 4,369
oligodendroglioma 17 | 2,849
psoriasis 17 | 6,685
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,289
pilocytic astrocytoma 14 | 3,086
pediatric high grade glioma 13 | 2,712
primitive neuroectodermal tumor 13 | 3,031
Breast cancer 12 | 3,094
ependymoma 12 | 2,514
malignant mesothelioma 12 | 3,162
group 4 medulloblastoma 11 | 1,875
invasive ductal carcinoma 11 | 2,950
lung cancer 11 | 4,466
medulloblastoma 10 | 1,524
astrocytic glioma 9 | 2,241
pancreatic cancer 9 | 2,300
subependymal giant cell astrocytoma 9 | 2,287
interstitial cystitis 8 | 2,299
lung carcinoma 8 | 2,844
Carcinoma 7 | 2,147
aldosterone-producing adenoma 7 | 664
group 3 medulloblastoma 7 | 2,254
pituitary cancer 7 | 1,972
ulcerative colitis 7 | 2,087
adrenocortical carcinoma 6 | 1,427
adult high grade glioma 6 | 2,148
ductal carcinoma in situ 6 | 1,745
gastric carcinoma 6 | 832
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,988
spina bifida 6 | 1,064
tuberculosis and treatment for 6 months 6 | 686
Multiple myeloma 5 | 1,327
breast carcinoma 5 | 1,614
diabetes mellitus 5 | 1,663
hepatocellular carcinoma 5 | 532
non-small cell lung cancer 5 | 2,798
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
posterior fossa group B ependymoma 5 | 1,530
primary pancreatic ductal adenocarcinoma 5 | 1,271
sonic hedgehog group medulloblastoma 5 | 1,482
tuberculosis 5 | 1,557
Nemaline myopathy 4 | 17
Pick disease 4 | 1,893
Pseudohypoaldosteronism 4 | 22
astrocytoma 4 | 1,493
gastric cancer 4 | 430
pancreatic carcinoma 4 | 567
posterior fossa group A ependymoma 4 | 1,511
primary Sjogren syndrome 4 | 789
sarcoidosis 4 | 358
Cancer 3 | 2,346
Parkinson's disease 3 | 364
active Crohn's disease 3 | 918
acute myeloid leukemia 3 | 780
acute quadriplegic myopathy 3 | 1,157
juvenile dermatomyositis 3 | 1,189
lung adenocarcinoma 3 | 2,713
nasopharyngeal carcinoma 3 | 1,056
Acquired metabolic disease 2 | 267
Atopic dermatitis 2 | 944
Cardiovascular system disease 2 | 194
Congenital myopathy 2 | 10
Gaucher disease type 1 2 | 171
Hypertension 2 | 287
Lipid metabolism disorder 2 | 102
Malaria 2 | 140
Multiple Sclerosis 2 | 498
Peripheral Neuropathy 2 | 303
Prostatic Neoplasms 2 | 471
Pseudohypoaldosteronism, Type II 2 | 2
Rheumatoid Arthritis 2 | 1,160
active ulcerative colitis 2 | 477
chronic rhinosinusitis 2 | 512
colon cancer 2 | 1,475
cystic fibrosis 2 | 1,665
type II diabetes mellitus and post-ischemic heart failure 2 | 89
Blood pressure finding 1 | 56
Chylomicron retention disease 1 | 11
Cleft palate 1 | 125
Corneal dystrophy 1 | 15
Dystonia 1 | 77
Endometrial Neoplasms 1 | 50
Gastrointestinal Diseases 1 | 12
Gorham's disease 1 | 3
Impotence 1 | 45
Muscle Weakness 1 | 92
Neutropenia 1 | 78
Osteoporosis 1 | 257
Retinitis pigmentosa 1 | 153
Systemic arterial pressure 1 | 56
Thrombocytopenia 1 | 105
Thyrotoxicosis 1 | 38
Zellweger Syndrome 1 | 38
cone-rod dystrophy 1 | 56
facioscapulohumeral dystrophy 1 | 286

Tissue

Cardiovascular System 65 | 17,958
Digestive Tract 65 | 18,473
Endocrine System 65 | 18,512
Female tissues 65 | 18,647
Liver and Pancreas 65 | 18,136
Male tissues 65 | 17,969
Nervous System 65 | 18,561
Skin and soft tissues 65 | 18,115
Urinary Tract 65 | 18,444
Blood and immune system 64 | 17,995
Respiratory system 64 | 17,484

Target Family

Non-IDG 62 | 11,971
Transcription Factor 2 | 1,400
Enzyme 1 | 4,146

GO Component

Cul3-RING ubiquitin ligase com... 65 | 65
nucleus 5,107 | 5,107
cytoplasm 4,985 | 4,985
plasma membrane 4,118 | 4,118
integral component of membrane 3,679 | 3,679
cytosol 3,265 | 3,265
extracellular exosome 2,758 | 2,758
nucleoplasm 2,717 | 2,717
membrane 1,906 | 1,906
extracellular region 1,493 | 1,493
integral component of plasma m... 1,406 | 1,406
extracellular space 1,304 | 1,304
mitochondrion 1,231 | 1,231
Golgi apparatus 864 | 864
endoplasmic reticulum 859 | 859
endoplasmic reticulum membrane 848 | 848
nucleolus 815 | 815
Golgi membrane 659 | 659
perinuclear region of cytoplas... 611 | 611
cell surface 594 | 594
intracellular 548 | 548
intracellular membrane-bounded... 537 | 537
cell junction 451 | 451
mitochondrial inner membrane 425 | 425
centrosome 409 | 409
focal adhesion 383 | 383
protein complex 355 | 355
cytoskeleton 343 | 343
dendrite 329 | 329
mitochondrial matrix 322 | 322
cell-cell adherens junction 307 | 307
neuronal cell body 303 | 303
microtubule 294 | 294
lysosomal membrane 278 | 278
apical plasma membrane 277 | 277
proteinaceous extracellular ma... 244 | 244
neuron projection 229 | 229
nuclear membrane 218 | 218
early endosome 217 | 217
axon 214 | 214
lysosome 210 | 210
endosome 208 | 208
actin cytoskeleton 205 | 205
external side of plasma membra... 205 | 205
postsynaptic membrane 204 | 204
extracellular matrix 198 | 198
nuclear speck 197 | 197
membrane raft 196 | 196
endoplasmic reticulum lumen 192 | 192
transcription factor complex 184 | 184
endosome membrane 182 | 182
early endosome membrane 180 | 180
basolateral plasma membrane 174 | 174
nuclear chromatin 169 | 169
synapse 166 | 166
cell-cell junction 161 | 161
nuclear envelope 156 | 156
lamellipodium 153 | 153
mitochondrial outer membrane 148 | 148
blood microparticle 147 | 147
myelin sheath 144 | 144
postsynaptic density 144 | 144
cytoplasmic vesicle 143 | 143
microtubule organizing center 137 | 137
cytoplasmic, membrane-bounded ... 132 | 132
ER to Golgi transport vesicle ... 131 | 131
microtubule cytoskeleton 127 | 127
receptor complex 127 | 127
phagocytic vesicle membrane 126 | 126
cytoplasmic vesicle membrane 125 | 125
midbody 125 | 125
trans-Golgi network 124 | 124
cell cortex 119 | 119
cilium 118 | 118
late endosome 116 | 116
spindle 116 | 116
intracellular ribonucleoprotei... 114 | 114
vesicle 112 | 112
Z disc 110 | 110
bicellular tight junction 110 | 110
anchored component of membrane 109 | 109
growth cone 109 | 109
integral component of lumenal ... 108 | 108
late endosome membrane 107 | 107
endomembrane system 106 | 106
centriole 105 | 105
recycling endosome 104 | 104
spindle pole 104 | 104
perikaryon 103 | 103
integral component of endoplas... 101 | 101
intermediate filament 101 | 101
melanosome 101 | 101
chromosome 100 | 100
dendritic spine 99 | 99
ubiquitin ligase complex 99 | 99
peroxisome 98 | 98
nuclear matrix 97 | 97
PML body 94 | 94
Golgi lumen 93 | 93
keratin filament 93 | 93
trans-Golgi network membrane 92 | 92

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Kelch-like protein 23 KLHL23 Tdark Non-IDG -0.01424 1.64 48
Kelch-like protein 10 KLHL10 Tdark Non-IDG -0.62839 4.48 35
Kelch-like protein 26 KLHL26 Tdark Non-IDG 0.60 0.08 76
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 KCTD13 Tbio Non-IDG -0.85155 7.65 69
Kelch-like protein 17 KLHL17 Tdark Non-IDG -0.22185 2.22 12
Kelch domain-containing protein 8A KLHDC8A Tdark Non-IDG 0.00000 72
Kelch repeat and BTB domain-containing protein 8 KBTBD8 Tdark Non-IDG 0.05 1.07 22
Kelch-like protein 24 KLHL24 Tbio Non-IDG -0.86041 8.77 62
Kelch-like protein 25 KLHL25 Tdark Non-IDG -0.41078 1.68 178
E3 ubiquitin-protein ligase RBX1 RBX1 Tbio Enzyme -1.88715 67.2 211