Development Level

Tbio 13 | 11,445
Tchem 2 | 1,598

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal heart morphology 1 | 162
abnormal heart shape 1 | 5
abnormal liver size 1 | 5
abnormal pericardium morpholog... 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
abnormal thymus morphology 1 | 7
abnormal urinary bladder morph... 1 | 11
decreased bone mineral density 1 | 126
decreased circulating serum al... 1 | 82
decreased prepulse inhibition 1 | 82
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
hydrometra 1 | 53
improved glucose tolerance 1 | 79
increased body weight 1 | 25
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 36
small seminal vesicle 1 | 10
small spleen 1 | 19
small superior vagus ganglion 1 | 74
small thymus 1 | 16

Disease

ovarian cancer 8 | 8,520
osteosarcoma 7 | 7,950
Carcinoma 6 | 11,493
Multiple myeloma 5 | 1,332
medulloblastoma, large-cell 4 | 6,241
psoriasis 4 | 6,694
Astrocytoma, Pilocytic 3 | 3,081
Cancer 3 | 2,499
Waldenstrons macroglobulinemia 3 | 765
astrocytic glioma 3 | 2,597
atypical teratoid / rhabdoid tumor 3 | 5,112
ependymoma 3 | 4,679
glioblastoma 3 | 5,792
group 4 medulloblastoma 3 | 1,855
lung cancer 3 | 4,740
oligodendroglioma 3 | 2,850
primitive neuroectodermal tumor 3 | 3,035
Pick disease 2 | 1,894
Schizophrenia 2 | 1,160
adult high grade glioma 2 | 3,801
lung carcinoma 2 | 2,843
malignant mesothelioma 2 | 3,232
AMYOTROPHIC LATERAL SCLEROSIS 1 1 | 49
Adult T-Cell Lymphoma/Leukemia 1 | 30
Alcoholic Intoxication, Chronic 1 | 289
Allergic hypersensitivity disease 1 | 126
Alzheimer's disease 1 | 658
Arthus reaction 1 | 7
Ascariasis 1 | 7
Asthma 1 | 385
Bipolar Disorder 1 | 666
Carcinoma, Hepatocellular 1 | 228
Celiac disease 1 | 116
Crohn's disease 1 | 321
Decubitus ulcer 1 | 13
Disease Progression 1 | 136
Endometriosis 1 | 540
Familial hypocalciuric hypercalcemia 1 | 20
HIV Infections 1 | 102
Hemangiosarcoma 1 | 18
Hepatomegaly 1 | 285
Hereditary renal cell carcinoma 1 | 3
Hereditary spherocytosis type 1 1 | 23
Leukemia-Lymphoma, Adult T-Cell 1 | 30
Liver carcinoma 1 | 240
Liver diseases 1 | 87
Lymphoma, T-Cell, Cutaneous 1 | 22
Lymphoproliferative syndrome 1 | 58
Melanoma 1 | 711
Neurotoxicity Syndromes 1 | 26
Obesity 1 | 678
Parapsoriasis 1 | 6
Persistent hyperplastic primary vitreous 1 | 20
Restrictive cardiomyopathy 1 | 11
Rheumatoid arthritis 1 | 1,191
Rhinitis 1 | 54
Scabies 1 | 7
Sezary Syndrome 1 | 27
Skin cancer 1 | 469
Smith-Magenis syndrome 1 | 29
Stevens-Johnson syndrome 1 | 92
Stomach Neoplasms 1 | 300
acute quadriplegic myopathy 1 | 1,158
breast carcinoma 1 | 1,638
colon cancer 1 | 1,478
diabetes mellitus 1 | 1,728
gastric cancer 1 | 459
group 3 medulloblastoma 1 | 4,104
hereditary spastic paraplegia 1 | 318
interstitial cystitis 1 | 2,312
invasive ductal carcinoma 1 | 2,951
juvenile dermatomyositis 1 | 1,187
medulloblastoma 1 | 720
non primary Sjogren syndrome sicca 1 | 891
pancreatic cancer 1 | 2,398
pancreatic ductal carcinoma 1 | 11
pediatric high grade glioma 1 | 1,064
sarcoidosis 1 | 370
sonic hedgehog group medulloblastoma 1 | 467
tuberculosis 1 | 2,010
tuberculosis and treatment for 6 months 1 | 409

Tissue

Blood and immune system 15 | 16,909
Cardiovascular System 15 | 15,192
Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Female tissues 15 | 17,400
Liver and Pancreas 15 | 16,750
Male tissues 15 | 17,142
Nervous System 15 | 16,725
Respiratory system 15 | 16,393
Skin and soft tissues 15 | 17,230
Urinary Tract 15 | 16,678

Target Family

Non-IDG 14 | 12,091
Enzyme 1 | 4,145

GO Component

COP9 signalosome 15 | 15
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Linker for activation of T-cells family member 1 LAT Tbio Non-IDG -2.16291 169.4 667
COP9 signalosome complex subunit 4 COPS4 Tbio Non-IDG -0.91181 7.39 88
COP9 signalosome complex subunit 9 COPS9 Tbio Non-IDG 0.21 0.92 14
COP9 signalosome complex subunit 7a COPS7A Tbio Non-IDG -1.50943 32.2 154
COP9 signalosome complex subunit 1 GPS1 Tbio Non-IDG -1.62973 42.8 246
COP9 signalosome complex subunit 3 COPS3 Tbio Non-IDG -1.12537 14.2 217
COP9 signalosome complex subunit 8 COPS8 Tbio Non-IDG -1.20410 15.8 166
COP9 signalosome complex subunit 2 COPS2 Tbio Non-IDG -0.95832 9.06 329
Growth factor receptor-bound protein 2 GRB2 Tchem Non-IDG -3.02404 981.4 501
Protein TESPA1 TESPA1 Tbio Non-IDG -0.73684 6.43 43