Development Level

Tbio 712 | 11,445
Tchem 127 | 1,598
Tclin 103 | 613
Tdark 96 | 6,588

Collection

RFA-RM-18-021 19 | 328
GPCR: IDG Consortium (Targets) 11 | 126
GPCR: IDG Consortium (Complete... 8 | 25
Ion Channel: IDG Consortium (T... 7 | 99

IMPC Phenotype

preweaning lethality, complete... 36 | 979
preweaning lethality, incomple... 29 | 499
abnormal behavior 23 | 298
enlarged heart 18 | 210
decreased vertical activity 16 | 208
decreased total body fat amoun... 13 | 207
abnormal heart morphology 11 | 162
embryonic lethality prior to t... 11 | 278
abnormal bone structure 10 | 187
abnormal embryo size 10 | 220
increased total body fat amoun... 10 | 134
abnormal seminal vesicle morph... 9 | 114
decreased bone mineral content 9 | 151
decreased startle reflex 9 | 75
improved glucose tolerance 9 | 79
abnormal sleep behavior 8 | 70
decreased grip strength 8 | 116
hyperactivity 8 | 148
hypoactivity 8 | 132
increased bone mineral content 8 | 108
increased lean body mass 8 | 172
increased mean corpuscular vol... 8 | 92
abnormal skin morphology 7 | 50
decreased circulating glucose ... 7 | 126
impaired glucose tolerance 7 | 75
increased heart weight 7 | 62
abnormal eye morphology 6 | 68
decreased body length 6 | 101
decreased circulating choleste... 6 | 93
decreased lean body mass 6 | 135
decreased leukocyte cell numbe... 6 | 73
enlarged spleen 6 | 41
short tibia 6 | 97
abnormal coat appearance 5 | 31
abnormal gait 5 | 69
abnormal retina morphology 5 | 71
abnormal spleen morphology 5 | 55
decreased blood urea nitrogen ... 5 | 51
decreased body weight 5 | 161
decreased bone mineral density 5 | 126
decreased lymphocyte cell numb... 5 | 83
decreased mean corpuscular vol... 5 | 79
increased circulating choleste... 5 | 66
increased circulating triglyce... 5 | 42
increased leukocyte cell numbe... 5 | 47
increased or absent threshold ... 5 | 101
male infertility 5 | 123
small superior vagus ganglion 5 | 74
tremors 5 | 39
abnormal coat-hair pigmentatio... 4 | 64
abnormal kidney morphology 4 | 65
abnormal limb bud morphology 4 | 17
abnormal pericardium morpholog... 4 | 26
cardiovascular system phenotyp... 4 | 36
cataract 4 | 92
decreased circulating triglyce... 4 | 79
decreased fasted circulating g... 4 | 65
decreased heart weight 4 | 27
decreased mean corpuscular hem... 4 | 31
decreased prepulse inhibition 4 | 82
embryonic growth retardation 4 | 106
embryonic lethality prior to o... 4 | 239
enlarged lymph nodes 4 | 37
female infertility 4 | 60
increased erythrocyte cell num... 4 | 39
increased fasted circulating g... 4 | 76
pale yolk sac 4 | 25
pallor 4 | 34
abnormal behavioral response t... 3 | 66
abnormal craniofacial morpholo... 3 | 33
abnormal neural tube closure 3 | 46
abnormal snout morphology 3 | 23
abnormal tail morphology 3 | 25
abnormal vibrissa morphology 3 | 25
decreased circulating HDL chol... 3 | 68
decreased circulating glycerol... 3 | 16
decreased eosinophil cell numb... 3 | 24
decreased erythrocyte cell num... 3 | 62
decreased heart rate 3 | 18
decreased mean corpuscular hem... 3 | 50
decreased neutrophil cell numb... 3 | 42
hydrometra 3 | 53
impaired righting response 3 | 26
increased bone mineral density 3 | 72
increased circulating HDL chol... 3 | 80
increased circulating alkaline... 3 | 122
increased circulating bilirubi... 3 | 16
increased circulating iron lev... 3 | 30
increased circulating sodium l... 3 | 71
increased hematocrit 3 | 46
increased hemoglobin content 3 | 45
increased mean corpuscular hem... 3 | 96
increased monocyte cell number 3 | 63
increased neutrophil cell numb... 3 | 46
increased vertical activity 3 | 24
microphthalmia 3 | 26
corneal opacity 2 | 32
decreased circulating insulin ... 2 | 76
increased circulating calcium ... 2 | 34
small testis 2 | 58

Disease

Carcinoma 780 | 11,493
ovarian cancer 573 | 8,520
osteosarcoma 510 | 7,950
psoriasis 510 | 6,694
glioblastoma 461 | 5,792
lung cancer 429 | 4,740
medulloblastoma, large-cell 414 | 6,241
lung carcinoma 392 | 2,843
atypical teratoid / rhabdoid tumor 367 | 5,112
ependymoma 354 | 4,679
Cancer 350 | 2,499
Breast cancer 338 | 3,578
invasive ductal carcinoma 332 | 2,951
malignant mesothelioma 319 | 3,232
non-small cell lung cancer 319 | 2,890
interstitial cystitis 315 | 2,312
Astrocytoma, Pilocytic 314 | 3,081
lung adenocarcinoma 301 | 2,716
intraductal papillary-mucinous adenoma (IPMA) 289 | 2,955
pancreatic cancer 287 | 2,398
adult high grade glioma 285 | 3,801
Kidney cancer 279 | 2,613
intraductal papillary-mucinous carcinoma (IPMC) 273 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 273 | 3,291
group 3 medulloblastoma 253 | 4,104
ulcerative colitis 243 | 1,819
tuberculosis 218 | 2,010
cystic fibrosis 213 | 1,696
ductal carcinoma in situ 207 | 1,745
oligodendroglioma 200 | 2,850
breast carcinoma 198 | 1,638
pituitary cancer 194 | 1,972
subependymal giant cell astrocytoma 193 | 2,287
diabetes mellitus 192 | 1,728
astrocytic glioma 173 | 2,597
primitive neuroectodermal tumor 173 | 3,035
colon cancer 157 | 1,478
pancreatic ductal adenocarcinoma liver metastasis 153 | 1,962
cutaneous lupus erythematosus 152 | 1,057
primary pancreatic ductal adenocarcinoma 150 | 1,109
adrenocortical carcinoma 144 | 1,428
group 4 medulloblastoma 139 | 1,855
Rheumatoid arthritis 138 | 1,191
Autosomal recessive predisposition 137 | 1,442
Schizophrenia 133 | 1,160
juvenile dermatomyositis 125 | 1,187
gastric carcinoma 122 | 807
Duchenne muscular dystrophy 119 | 601
Pick disease 118 | 1,894
Atopic dermatitis 113 | 952
Liver Cirrhosis, Experimental 105 | 769
Multiple Sclerosis 100 | 540
dermatomyositis 99 | 966
Hypersensitivity reaction type II disease 98 | 253
nasopharyngeal carcinoma 98 | 1,058
astrocytoma 97 | 1,146
pediatric high grade glioma 95 | 1,064
primary Sjogren syndrome 93 | 735
Melanoma 91 | 711
active Crohn's disease 90 | 922
esophageal adenocarcinoma 90 | 737
autosomal dominant Emery-Dreifuss muscular dystrophy 87 | 510
acute quadriplegic myopathy 84 | 1,158
mucosa-associated lymphoid tissue lymphoma 81 | 484
Alzheimer's disease 80 | 658
Kidney disease 80 | 430
Skin cancer 78 | 469
fibroadenoma 78 | 559
Liver cancer 77 | 604
Arthritis 74 | 290
active ulcerative colitis 71 | 764
Anemia 70 | 365
Asthma 69 | 385
Atherosclerosis 64 | 291
Down syndrome 63 | 499
Hypertension 63 | 396
spina bifida 61 | 1,074
Bipolar Disorder 60 | 666
Liver disease 59 | 237
Multiple myeloma 59 | 1,332
aldosterone-producing adenoma 59 | 665
Breast Neoplasms 57 | 445
Coronary artery disease 57 | 268
Obesity 57 | 678
posterior fossa group A ependymoma 56 | 468
Human immunodeficiency virus infectious disease 55 | 138
Mammary Neoplasms 55 | 425
Intellectual disability 53 | 1,016
Ankylosing spondylitis 51 | 140
sarcoidosis 51 | 370
limb girdle muscular dystrophy 2A 50 | 213
non primary Sjogren syndrome sicca 50 | 891
Endometriosis 49 | 540
Prostatic Neoplasms 49 | 495
Vascular disease 49 | 319
Becker muscular dystrophy 48 | 191
interstitial lung disease 48 | 298
non-small cell lung carcinoma 48 | 317
acute myeloid leukemia 47 | 783
periodontitis 47 | 293

Tissue

Endocrine System 972 | 18,159
Female tissues 971 | 17,400
Skin and soft tissues 971 | 17,230
Digestive Tract 969 | 17,369
Male tissues 967 | 17,142
Blood and immune system 966 | 16,909
Urinary Tract 964 | 16,678
Liver and Pancreas 962 | 16,750
Respiratory system 957 | 16,393
Nervous System 944 | 16,725
Cardiovascular System 906 | 15,192

Target Family

Non-IDG 740 | 12,091
Enzyme 117 | 4,145
GPCR 70 | 408
Kinase 48 | 634
Transporter 38 | 473
Ion Channel 23 | 344
Transcription Factor 2 | 1,400

Data Source

Cell Surface Protein Atlas 1,038 | 1,038
TCRDv5.4.0 20,244 | 20,244
UniProt 20,244 | 20,244
HCA RNA 18,868 | 18,868
GTEx 18,679 | 18,679
Consensus 18,503 | 18,503
HPA RNA 18,499 | 18,499
UniProt Tissue 17,989 | 17,989
OMA 17,919 | 17,919
Inparanoid 17,402 | 17,402
JensenLab Experiment HPA-RNA 16,979 | 16,979
JensenLab Knowledge UniProtKB-... 16,759 | 16,759
Expression Atlas 16,585 | 16,585
EggNOG 16,566 | 16,566
HPM Protein 16,251 | 16,251
HPM Gene 16,026 | 16,026
JensenLab Experiment RNA-seq 15,916 | 15,916
JensenLab Experiment HPM 15,886 | 15,886
JensenLab Experiment HPA 15,665 | 15,665
JensenLab Text Mining 15,169 | 15,169
JensenLab Experiment UniGene 14,935 | 14,935
JensenLab Experiment Exon arra... 13,611 | 13,611
JensenLab Experiment COSMIC 11,445 | 11,445
JensenLab Experiment GNF 10,637 | 10,637
HPA Protein 10,414 | 10,414
GWAS Catalog 10,255 | 10,255
JAX/MGI Human Ortholog Phenoty... 9,720 | 9,720
DisGeNET 7,631 | 7,631
CTD 7,446 | 7,446
BioPlex 6,400 | 6,400
JensenLab Experiment DistiLD 3,914 | 3,914
Monarch 3,826 | 3,826
OMIM 3,731 | 3,731
IMPC 3,485 | 3,485
JensenLab Knowledge UniProtKB-... 2,279 | 2,279
JensenLab Knowledge GHR 2,052 | 2,052
Reactome 1,920 | 1,920
DrugCentral Indication 910 | 910

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Carcinoembryonic antigen-related cell adhesion molecule 8 CEACAM8 Tbio Non-IDG -2.27709 182.9 314
Post-GPI attachment to proteins factor 6 TMEM8A Tdark Non-IDG -0.56820 3.55 16
HLA class I histocompatibility antigen, B-35 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 0
Protocadherin gamma-A9 PCDHGA9 Tdark Non-IDG 0.51 0.72 31
Protocadherin gamma-B7 PCDHGB7 Tdark Non-IDG -1.62113 42.6 4
Trophoblast glycoprotein TPBG Tbio Non-IDG -2.10560 136.9 206
Protocadherin gamma-B5 PCDHGB5 Tdark Non-IDG 0.00000 25
Choline transporter-like protein 1 SLC44A1 Tbio Transporter -1.60796 43.9 212
5-hydroxytryptamine receptor 2B HTR2B Tclin GPCR -2.66641 486.3 265
Protocadherin gamma-A8 PCDHGA8 Tdark Non-IDG 0.00000 1.00 96