Development Level

Tchem 1 | 1,598

IMPC Phenotype

abnormal lens morphology 1 | 81
embryonic lethality prior to t... 1 | 278
preweaning lethality, complete... 1 | 979

Disease

Abnormality of the metaphyses 1 | 48
Abnormally-shaped vertebrae 1 | 31
Absent/hypoplastic paranasal sinuses 1 | 5
Acquired scoliosis 1 | 281
Advanced bone age 1 | 35
Agenesis of teeth 1 | 21
Attention deficit hyperactivity disorder 1 | 278
Bowing of the long bones 1 | 31
Byzanthine arch palate 1 | 194
Carcinoma 1 | 11,493
Cardiospondylocarpofacial Syndrome 1 | 1
Cholestasis, Extrahepatic 1 | 25
Conductive hearing loss 1 | 123
Congenital sensorineural hearing loss 1 | 12
Craniofacial hyperostosis 1 | 11
Curvature of spine 1 | 282
Dental abnormalities 1 | 60
Disorder of eye 1 | 27
Downward slant of palpebral fissure 1 | 158
Enlargement of craniofacial bones 1 | 11
Eye Abnormalities 1 | 35
Flexion contracture of proximal interphalangeal joint 1 | 75
Forney Robinson Pascoe syndrome 1 | 1
Freckles 1 | 33
Frontometaphyseal dysplasia 1 | 2
Fused cervical vertebrae 1 | 5
Hamman-Rich syndrome 1 | 34
Hyperplasia of supraorbital margins 1 | 19
Hyperplasia of supraorbital ridge 1 | 19
Hypertrophy of craniofacial bones 1 | 11
Hypertrophy of supraorbital margins 1 | 19
Hypertrophy of supraorbital ridge 1 | 19
Hypoplasia of muscle 1 | 5
Hypoplastic mandible condyle 1 | 275
Irregular metacarpals 1 | 2
Joint stiffness 1 | 84
Kidney cancer 1 | 2,613
Long fingers 1 | 9
Long metacarpals 1 | 2
Mandibular hypoplasia 1 | 275
Micrognathism 1 | 275
Mitral Regurgitation, Conductive Deafness, and Fusion of Cervical Vertebrae and of Carpal and Tarsal Bones 1 | 1
Mitral regurgitation, mild 1 | 32
Mitral valve insufficiency 1 | 49
Orbital separation excessive 1 | 244
Posterior vertebral hypoplasia 1 | 3
Prominent supraorbital ridges 1 | 19
Prostatic Neoplasms 1 | 495
Reduced number of teeth 1 | 21
Sensorineural Hearing Loss (disorder) 1 | 284
Short distal phalanx of hallux 1 | 2
Short stature 1 | 531
Short thumb terminal phalanx 1 | 5
Synostosis of carpal bones 1 | 9
Synostosis of carpals/tarsals 1 | 1
Thick craniofacial bones 1 | 11
Tooth Abnormalities 1 | 69
Ulnar deviation of the fingers 1 | 21
acute quadriplegic myopathy 1 | 1,158
atypical teratoid / rhabdoid tumor 1 | 5,112
dermatomyositis 1 | 966
glioblastoma 1 | 5,792
group 4 medulloblastoma 1 | 1,855
juvenile dermatomyositis 1 | 1,187
lung adenocarcinoma 1 | 2,716
lung cancer 1 | 4,740
non-small cell lung cancer 1 | 2,890
osteosarcoma 1 | 7,950
ovarian cancer 1 | 8,520
primary pancreatic ductal adenocarcinoma 1 | 1,109
psoriasis 1 | 6,694

Tissue

Blood and immune system 1 | 16,909
Cardiovascular System 1 | 15,192
Digestive Tract 1 | 17,369
Endocrine System 1 | 18,159
Female tissues 1 | 17,400
Liver and Pancreas 1 | 16,750
Male tissues 1 | 17,142
Nervous System 1 | 16,725
Respiratory system 1 | 16,393
Skin and soft tissues 1 | 17,230
Urinary Tract 1 | 16,678

Target Family

Kinase 1 | 634

DTO Protein Class (4)

TAK1 subfamily 1 | 1
STKR Type 1 subfamily 7 | 7
ERK subfamily 5 | 5
GRK subfamily 5 | 5
STKR Type 2 subfamily 5 | 5
TAIRE subfamily 5 | 5
ATR subfamily 4 | 4
GEK subfamily 4 | 4
HIPK subfamily 4 | 4
KHS subfamily 4 | 4
MARK subfamily 4 | 4
MLK subfamily 4 | 4
P38 subfamily 4 | 4
PAKA subfamily 4 | 4
RSK subfamily 4 | 4
CDK1 subfamily 3 | 3
Dyrk2 subfamily 3 | 3
JNK subfamily 3 | 3
MAPKAPK subfamily 3 | 3
MSN subfamily 3 | 3
PAKB subfamily 3 | 3
PKC alpha subfamily 3 | 3
QIK subfamily 3 | 3
TAO subfamily 3 | 3
YSK subfamily 3 | 3
ABC1-A subfamily 2 | 2
ABC1-B subfamily 2 | 2
AK3 subfamily 2 | 2
AMPK subfamily 2 | 2
BARK subfamily 2 | 2
BRSK subfamily 2 | 2
CDK4 subfamily 2 | 2
CDK8 subfamily 2 | 2
Dyrk1 subfamily 2 | 2
FRAY subfamily 2 | 2
GSK subfamily 2 | 2
LIMK subfamily 2 | 2
MNK subfamily 2 | 2
MSK subfamily 2 | 2
MST subfamily> 2 | 2
Meta subfamily 2 | 2
NMO subfamily 2 | 2
NinaC subfamily 2 | 2
NuaK subfamily 2 | 2
P70 subfamily 2 | 2
PITSLRE subfamily 2 | 2
PKC delta subfamily 2 | 2
PKC eta subfamily 2 | 2
PKC iota subfamily 2 | 2
ROCK subfamily 2 | 2
SLK subfamily 2 | 2
ABC1-C subfamily 1 | 1
AK1 subfamily 1 | 1
AK2 subfamily 1 | 1
ATP-dependent PFK group I subf... 1 | 1
CCRK subfamily 1 | 1
CDK10 subfamily 1 | 1
CDK5 subfamily 1 | 1
CDK7 subfamily 1 | 1
CDK9 subfamily 1 | 1
CHK1 subfamily 1 | 1
CRK7 subfamily 1 | 1
ChaK subfamily 1 | 1
DNAPK subfamily 1 | 1
EEF2K subfamily 1 | 1
Erk7 subfamily 1 | 1
FRAP subfamily 1 | 1
GCN2 subfamily 1 | 1
HH498 subfamily 1 | 1
HUNK subfamily 1 | 1
ILK subfamily 1 | 1
LKB subfamily 1 | 1
LZK subfamily 1 | 1
MELK subfamily 1 | 1
Mevalonate kinase subfamily 1 | 1
NIM1 subfamily 1 | 1
PASK subfamily 1 | 1
PDHK subfamily 1 | 1
PDK1 subfamily 1 | 1
PEK subfamily 1 | 1
PLK2 subfamily 1 | 1
RIO1 subfamily 1 | 1
RIO2 subfamily 1 | 1
RIO3 subfamily 1 | 1
SNRK subfamily 1 | 1
TESK subfamily 1 | 1
Type II PI4K subfamily 1 | 1
Type III PI4K subfamily 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mitogen-activated protein kinase kinase kinase 7 MAP3K7 Tchem Kinase -1.46817 32.4 765