Development Level

Tchem 6 | 1,598
Tbio 1 | 11,445

IMPC Phenotype

embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
preweaning lethality, complete... 2 | 979
abnormal bone structure 1 | 187
abnormal coat- hair morphology 1 | 19
abnormal embryo size 1 | 220
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
decreased blood urea nitrogen ... 1 | 51
increased prepulse inhibition 1 | 32
small adrenal glands 1 | 16
small superior vagus ganglion 1 | 74
small testis 1 | 58

Disease

Carcinoma 7 | 11,493
osteosarcoma 6 | 7,950
ovarian cancer 6 | 8,520
psoriasis 5 | 6,694
Cancer 4 | 2,499
Fibrodysplasia ossificans progressiva 4 | 17
atypical teratoid / rhabdoid tumor 4 | 5,112
glioblastoma 4 | 5,792
Astrocytoma, Pilocytic 3 | 3,081
Hereditary hemorrhagic telangiectasia 3 | 13
adult high grade glioma 3 | 3,801
astrocytoma 3 | 1,146
breast carcinoma 3 | 1,638
ependymoma 3 | 4,679
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
invasive ductal carcinoma 3 | 2,951
lung carcinoma 3 | 2,843
medulloblastoma, large-cell 3 | 6,241
Acquired scoliosis 2 | 281
Anemia 2 | 365
Bilateral fifth finger clinodactyly 2 | 110
Breast cancer 2 | 3,578
Bunion 2 | 26
Craniofacial Abnormalities 2 | 151
Curvature of little finger 2 | 110
Curvature of spine 2 | 282
Decreased joint mobility 2 | 53
Eye Abnormalities 2 | 35
Hallux Valgus 2 | 26
Heart disease 2 | 306
Hemoglobin low 2 | 124
Hypertensive disease 2 | 292
Increase in blood pressure 2 | 119
Kidney cancer 2 | 2,613
Liver Cirrhosis 2 | 181
Myositis ossificans 2 | 5
Primary pulmonary hypertension 2 | 14
Short hallux 2 | 16
Systemic scleroderma 2 | 60
active ulcerative colitis 2 | 764
acute quadriplegic myopathy 2 | 1,158
astrocytic glioma 2 | 2,597
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
primitive neuroectodermal tumor 2 | 3,035
ulcerative colitis 2 | 1,819
Abnormality of the hip bone 1 | 16
Abnormality of the iris 1 | 14
Abnormality of the tibia 1 | 9
Abnormality of the ulna 1 | 10
Absent/hypoplastic middle phalanx of 5th finger 1 | 4
Aneurysm, Dissecting 1 | 8
Aortic aneurysm, familial thoracic 3 1 | 13
Aplasia/Hypoplasia involving the metacarpal bones 1 | 5
Ascending aortic dissection 1 | 13
BRACHYDACTYLY, TYPE A2 1 | 4
Bannayan-Riley-Ruvalcaba syndrome 1 | 8
Bone Diseases, Developmental 1 | 27
Broad femoral neck 1 | 4
Broad hallux 1 | 29
Camurati-Engelmann disease 1 | 6
Choriocapillaris atrophy 1 | 1
Cone-shaped epiphyses 1 | 24
Cowden disease 1 | 18
Descending aortic dissection 1 | 13
Dissection of aorta 1 | 9
Familial thoracic aortic aneurysm and aortic dissection 1 | 13
Fibular aplasia 1 | 6
Hamartoma Syndrome, Multiple 1 | 10
Hereditary hemorrhagic telangiectasia type 2 1 | 1
Hypoplastic finger 1 | 17
Hypoplastic/aplastic middle phalanx (2nd finger) 1 | 4
Impaired left ventricular function 1 | 16
Loeys-Dietz Aortic Aneurysm Syndrome 1 | 13
Metaphyseal widening 1 | 22
Multiple colonic adenomatous polyps 1 | 3
Multiple, subcutaneous nodules 1 | 53
Narrow nose 1 | 20
OSLER-RENDU-WEBER SYNDROME 2 1 | 1
Pericardial effusion 1 | 14
Pinched bridge of nose 1 | 14
Pinched nasal bridge 1 | 14
Polyposis, Gastric 1 | 4
Proximal symphalangism 1 | 7
Second finger clinodactyly 1 | 5
Short femoral neck 1 | 15
Short finger 1 | 17
Short first metacarpals 1 | 11
Short index finger 1 | 6
Short middle phalanges 1 | 12
Short middle phalanx of the 5th finger 1 | 13
Short phalanx of finger 1 | 32
Subcutaneous nodule 1 | 53
Synostosis of carpal bones 1 | 9
Thoracic aortic aneurysm 1 | 15
Ulnar angulation of the index finger 1 | 5
Ureteral obstruction 1 | 33
Uterine Rupture 1 | 2
Vascular Remodeling 1 | 3

Tissue

Blood and immune system 7 | 16,909
Cardiovascular System 7 | 15,192
Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Male tissues 7 | 17,142
Nervous System 7 | 16,725
Respiratory system 7 | 16,393
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678

Target Family

Kinase 7 | 634

DTO Protein Class (4)

STKR Type 1 subfamily 7 | 7
ERK subfamily 5 | 5
GRK subfamily 5 | 5
STKR Type 2 subfamily 5 | 5
TAIRE subfamily 5 | 5
ATR subfamily 4 | 4
GEK subfamily 4 | 4
HIPK subfamily 4 | 4
KHS subfamily 4 | 4
MARK subfamily 4 | 4
MLK subfamily 4 | 4
P38 subfamily 4 | 4
PAKA subfamily 4 | 4
RSK subfamily 4 | 4
CDK1 subfamily 3 | 3
Dyrk2 subfamily 3 | 3
JNK subfamily 3 | 3
MAPKAPK subfamily 3 | 3
MSN subfamily 3 | 3
PAKB subfamily 3 | 3
PKC alpha subfamily 3 | 3
QIK subfamily 3 | 3
TAO subfamily 3 | 3
YSK subfamily 3 | 3
ABC1-A subfamily 2 | 2
ABC1-B subfamily 2 | 2
AK3 subfamily 2 | 2
AMPK subfamily 2 | 2
BARK subfamily 2 | 2
BRSK subfamily 2 | 2
CDK4 subfamily 2 | 2
CDK8 subfamily 2 | 2
Dyrk1 subfamily 2 | 2
FRAY subfamily 2 | 2
GSK subfamily 2 | 2
LIMK subfamily 2 | 2
MNK subfamily 2 | 2
MSK subfamily 2 | 2
MST subfamily> 2 | 2
Meta subfamily 2 | 2
NMO subfamily 2 | 2
NinaC subfamily 2 | 2
NuaK subfamily 2 | 2
P70 subfamily 2 | 2
PITSLRE subfamily 2 | 2
PKC delta subfamily 2 | 2
PKC eta subfamily 2 | 2
PKC iota subfamily 2 | 2
ROCK subfamily 2 | 2
SLK subfamily 2 | 2
ABC1-C subfamily 1 | 1
AK1 subfamily 1 | 1
AK2 subfamily 1 | 1
ATP-dependent PFK group I subf... 1 | 1
CCRK subfamily 1 | 1
CDK10 subfamily 1 | 1
CDK5 subfamily 1 | 1
CDK7 subfamily 1 | 1
CDK9 subfamily 1 | 1
CHK1 subfamily 1 | 1
CRK7 subfamily 1 | 1
ChaK subfamily 1 | 1
DNAPK subfamily 1 | 1
EEF2K subfamily 1 | 1
Erk7 subfamily 1 | 1
FRAP subfamily 1 | 1
GCN2 subfamily 1 | 1
HH498 subfamily 1 | 1
HUNK subfamily 1 | 1
ILK subfamily 1 | 1
LKB subfamily 1 | 1
LZK subfamily 1 | 1
MELK subfamily 1 | 1
Mevalonate kinase subfamily 1 | 1
NIM1 subfamily 1 | 1
PASK subfamily 1 | 1
PDHK subfamily 1 | 1
PDK1 subfamily 1 | 1
PEK subfamily 1 | 1
PLK2 subfamily 1 | 1
RIO1 subfamily 1 | 1
RIO2 subfamily 1 | 1
RIO3 subfamily 1 | 1
SNRK subfamily 1 | 1
TAK1 subfamily 1 | 1
TESK subfamily 1 | 1
Type II PI4K subfamily 1 | 1
Type III PI4K subfamily 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Bone morphogenetic protein receptor type-1B BMPR1B Tchem Kinase -2.00303 86.8 498
Activin receptor type-1B ACVR1B Tchem Kinase -2.00550 91.2 418
Bone morphogenetic protein receptor type-1A BMPR1A Tchem Kinase -2.34984 211.0 622
Serine/threonine-protein kinase receptor R3 ACVRL1 Tchem Kinase -2.98370 969.8 432
Activin receptor type-1C ACVR1C Tbio Kinase -1.53432 40.5 303
TGF-beta receptor type-1 TGFBR1 Tchem Kinase -2.94747 847.9 413
Activin receptor type-1 ACVR1 Tchem Kinase -2.47071 290.9 428