Development Level

Tchem 3 | 1,598

IMPC Phenotype

abnormal bone structure 1 | 187
abnormal clavicle morphology 1 | 6
abnormal joint morphology 1 | 23
abnormal optic disc morphology 1 | 10
decreased circulating iron lev... 1 | 32
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30

Disease

Carcinoma 2 | 11,493
ependymoma 2 | 4,679
glioblastoma 2 | 5,792
osteosarcoma 2 | 7,950
psoriasis 2 | 6,694
COPD 1 | 118
Congenital nonspherocytic hemolytic anemia 1 | 5
Endemic typhus 1 | 2
Immature cataract 1 | 3
Patterned dystrophy of retinal pigment epithelium 1 | 3
Pilocytic astrocytoma 1 | 56
Vitamin K deficiency hemorrhagic disease 1 | 11
atypical teratoid / rhabdoid tumor 1 | 5,112
breast carcinoma 1 | 1,638
colon cancer 1 | 1,478
dermatomyositis 1 | 966
invasive ductal carcinoma 1 | 2,951
lung cancer 1 | 4,740
malignant mesothelioma 1 | 3,232
medulloblastoma 1 | 720
medulloblastoma, large-cell 1 | 6,241
pediatric high grade glioma 1 | 1,064
pituitary cancer 1 | 1,972
primitive neuroectodermal tumor 1 | 3,035
tuberculosis 1 | 2,010
ulcerative colitis 1 | 1,819

Tissue

Blood and immune system 3 | 16,909
Cardiovascular System 3 | 15,192
Digestive Tract 3 | 17,369
Endocrine System 3 | 18,159
Female tissues 3 | 17,400
Liver and Pancreas 3 | 16,750
Male tissues 3 | 17,142
Nervous System 3 | 16,725
Respiratory system 3 | 16,393
Skin and soft tissues 3 | 17,230
Urinary Tract 3 | 16,678

Target Family

Kinase 3 | 634

DTO Protein Class (4)

MAPKAPK subfamily 3 | 3
STKR Type 1 subfamily 7 | 7
ERK subfamily 5 | 5
GRK subfamily 5 | 5
STKR Type 2 subfamily 5 | 5
TAIRE subfamily 5 | 5
ATR subfamily 4 | 4
GEK subfamily 4 | 4
HIPK subfamily 4 | 4
KHS subfamily 4 | 4
MARK subfamily 4 | 4
MLK subfamily 4 | 4
P38 subfamily 4 | 4
PAKA subfamily 4 | 4
RSK subfamily 4 | 4
CDK1 subfamily 3 | 3
Dyrk2 subfamily 3 | 3
JNK subfamily 3 | 3
MSN subfamily 3 | 3
PAKB subfamily 3 | 3
PKC alpha subfamily 3 | 3
QIK subfamily 3 | 3
TAO subfamily 3 | 3
YSK subfamily 3 | 3
ABC1-A subfamily 2 | 2
ABC1-B subfamily 2 | 2
AK3 subfamily 2 | 2
AMPK subfamily 2 | 2
BARK subfamily 2 | 2
BRSK subfamily 2 | 2
CDK4 subfamily 2 | 2
CDK8 subfamily 2 | 2
Dyrk1 subfamily 2 | 2
FRAY subfamily 2 | 2
GSK subfamily 2 | 2
LIMK subfamily 2 | 2
MNK subfamily 2 | 2
MSK subfamily 2 | 2
MST subfamily> 2 | 2
Meta subfamily 2 | 2
NMO subfamily 2 | 2
NinaC subfamily 2 | 2
NuaK subfamily 2 | 2
P70 subfamily 2 | 2
PITSLRE subfamily 2 | 2
PKC delta subfamily 2 | 2
PKC eta subfamily 2 | 2
PKC iota subfamily 2 | 2
ROCK subfamily 2 | 2
SLK subfamily 2 | 2
ABC1-C subfamily 1 | 1
AK1 subfamily 1 | 1
AK2 subfamily 1 | 1
ATP-dependent PFK group I subf... 1 | 1
CCRK subfamily 1 | 1
CDK10 subfamily 1 | 1
CDK5 subfamily 1 | 1
CDK7 subfamily 1 | 1
CDK9 subfamily 1 | 1
CHK1 subfamily 1 | 1
CRK7 subfamily 1 | 1
ChaK subfamily 1 | 1
DNAPK subfamily 1 | 1
EEF2K subfamily 1 | 1
Erk7 subfamily 1 | 1
FRAP subfamily 1 | 1
GCN2 subfamily 1 | 1
HH498 subfamily 1 | 1
HUNK subfamily 1 | 1
ILK subfamily 1 | 1
LKB subfamily 1 | 1
LZK subfamily 1 | 1
MELK subfamily 1 | 1
Mevalonate kinase subfamily 1 | 1
NIM1 subfamily 1 | 1
PASK subfamily 1 | 1
PDHK subfamily 1 | 1
PDK1 subfamily 1 | 1
PEK subfamily 1 | 1
PLK2 subfamily 1 | 1
RIO1 subfamily 1 | 1
RIO2 subfamily 1 | 1
RIO3 subfamily 1 | 1
SNRK subfamily 1 | 1
TAK1 subfamily 1 | 1
TESK subfamily 1 | 1
Type II PI4K subfamily 1 | 1
Type III PI4K subfamily 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
MAP kinase-activated protein kinase 2 MAPKAPK2 Tchem Kinase -2.16502 140.7 702
MAP kinase-activated protein kinase 5 MAPKAPK5 Tchem Kinase -1.87360 78.8 436
MAP kinase-activated protein kinase 3 MAPKAPK3 Tchem Kinase -1.71703 51.6 242