Development Level

Tbio 1 | 11,445
Tchem 1 | 1,598

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

abnormal clavicle morphology 1 | 6
abnormal eyelid morphology 1 | 7
abnormal femur morphology 1 | 14
abnormal fibula morphology 1 | 2
abnormal gait 1 | 69
abnormal humerus morphology 1 | 11
abnormal joint morphology 1 | 23
abnormal locomotor behavior 1 | 24
abnormal mandible morphology 1 | 2
abnormal maxilla morphology 1 | 17
abnormal pelvic girdle bone mo... 1 | 12
abnormal radius morphology 1 | 8
abnormal rib morphology 1 | 10
abnormal snout morphology 1 | 23
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 18
abnormal zygomatic bone morpho... 1 | 3
absent teeth 1 | 3
decreased basophil cell number 1 | 16
decreased circulating alkaline... 1 | 46
decreased eosinophil cell numb... 1 | 24
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating aspartat... 1 | 15
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased neutrophil cell numb... 1 | 46
increased red blood cell distr... 1 | 34
increased spleen weight 1 | 10
short tibia 1 | 97
small thymus 1 | 16
thrombocytopenia 1 | 56

Disease

Carcinoma 2 | 11,493
Kidney cancer 2 | 2,613
Parkinson's disease 2 | 392
atypical teratoid / rhabdoid tumor 2 | 5,112
lung carcinoma 2 | 2,843
medulloblastoma, large-cell 2 | 6,241
osteosarcoma 2 | 7,950
Alzheimer's disease 1 | 658
Astrocytoma, Pilocytic 1 | 3,081
Autosomal dominant late onset Parkinson disease 1 | 7
Carcinoma, Renal Cell 1 | 124
Common variable immunodeficiency 1 | 101
Corneal disease 1 | 31
Crohn's disease 1 | 321
Dementia 1 | 175
Depressive Symptoms 1 | 28
Endometriosis 1 | 540
Large intestine cancer 1 | 126
Leprosy 1 | 73
Melanoma 1 | 711
Metaphyseal dysplasia 1 | 11
Movement disease 1 | 11
Multiple system atrophy 1 | 29
Nerve Degeneration 1 | 121
Neurodegenerative disease 1 | 414
Osteopetrosis 1 | 43
PARKINSON DISEASE 19, JUVENILE-ONSET 1 | 10
PARKINSON DISEASE 8 (disorder) 1 | 1
PARKINSON DISEASE 8, AUTOSOMAL DOMINANT 1 | 1
PARKINSON DISEASE, LATE-ONSET 1 | 20
Parkinson Disease 1 | 64
Parkinsonian Disorders 1 | 56
Pick disease 1 | 1,894
REM sleep behavior disorder 1 | 14
Renal Cell Carcinoma 1 | 214
Schizophrenia 1 | 1,160
Skin cancer 1 | 469
Toxic encephalopathy 1 | 141
Young onset Parkinson disease 1 | 10
acute quadriplegic myopathy 1 | 1,158
autosomal dominant Parkinson disease 8 1 | 1
cystic fibrosis 1 | 1,696
diabetes mellitus 1 | 1,728
glioblastoma 1 | 5,792
group 3 medulloblastoma 1 | 4,104
group 4 medulloblastoma 1 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
invasive ductal carcinoma 1 | 2,951
lung adenocarcinoma 1 | 2,716
mucosa-associated lymphoid tissue lymphoma 1 | 484
non-small cell lung cancer 1 | 2,890
ovarian cancer 1 | 8,520
primitive neuroectodermal tumor 1 | 3,035
tuberculosis 1 | 2,010
ulcerative colitis 1 | 1,819

Tissue

Blood and immune system 2 | 16,909
Cardiovascular System 2 | 15,192
Digestive Tract 2 | 17,369
Endocrine System 2 | 18,159
Female tissues 2 | 17,400
Liver and Pancreas 2 | 16,750
Male tissues 2 | 17,142
Nervous System 2 | 16,725
Respiratory system 2 | 16,393
Skin and soft tissues 2 | 17,230
Urinary Tract 2 | 16,678

Target Family

Kinase 2 | 634

DTO Protein Class (3)

LRRK family 2 | 2
STE20 family 31 | 31
CAMKL family 22 | 22
CDK family 21 | 21
MAPK family 15 | 15
EPH family 14 | 14
C-C chemokine receptor 13 | 13
STKR family 12 | 12
NEK family 11 | 11
PI3-PI4 kinase family 11 | 11
SRC family 11 | 11
DYRK family 10 | 10
MLK family 10 | 10
P2Y receptor 10 | 10
PKC family 9 | 9
DMPK family 8 | 8
PIKK family 8 | 8
RSK family 8 | 8
STE11 family 8 | 8
CK1 family 7 | 7
CLK family 7 | 7
GRK family 7 | 7
RAF family 7 | 7
STE7 family 7 | 7
Alpha adrenoceptor 6 | 6
MAST family 6 | 6
RGC family 6 | 6
SCY1 family 6 | 6
TEC family 6 | 6
5-HT1 receptor 5 | 5
5-HT3 receptor sub-subfamily 5 | 5
ABC1 family 5 | 5
Alpha family 5 | 5
CAMK1 family 5 | 5
CDKL family 5 | 5
DAPK family 5 | 5
MAPKAPK family 5 | 5
MLCK family 5 | 5
PDGFR family 5 | 5
PDHK family 5 | 5
PKA family 5 | 5
PLK family 5 | 5
RIPK family 5 | 5
TSSK family 5 | 5
ULK family 5 | 5
Adenylate kinase family 4 | 4
C-X-C chemokine receptor 4 | 4
CAMK2 family 4 | 4
CK2 family 4 | 4
EGFR family 4 | 4
FGFR family 4 | 4
Hexokinase family 4 | 4
IKK family 4 | 4
IRAK family 4 | 4
JAKA family 4 | 4
LISK family 4 | 4
NAK family 4 | 4
NDR family 4 | 4
PEK family 4 | 4
PIM family 4 | 4
TRIO family 4 | 4
WNK family 4 | 4
5-HT2 receptor 3 | 3
AKT family 3 | 3
AUR family 3 | 3
AXL family 3 | 3
Beta adrenoceptor 3 | 3
DCAMKL family 3 | 3
DCK-DGK family 3 | 3
Diacylglycerol kinase family 3 | 3
INSR family 3 | 3
Inositol phosphokinase (IPK) f... 3 | 3
LMR family 3 | 3
MET family 3 | 3
NKF1 family 3 | 3
Other-UNIQUE family 3 | 3
PKD family 3 | 3
PKN family 3 | 3
RCK family 3 | 3
RIO family 3 | 3
SGK family 3 | 3
SRPK family 3 | 3
TRBL family 3 | 3
TRK family 3 | 3
Type II pantothenate kinase fa... 3 | 3
VEGFR family 3 | 3
VRK family 3 | 3
WEE family 3 | 3
YANK family 3 | 3
ABL family 2 | 2
ACK family 2 | 2
Alpha-7-CHRNA7 sub-subfamily 2 | 2
BUB family 2 | 2
CAMK-UNIQUE family 2 | 2
CSK family 2 | 2
FGGY kinase family 2 | 2
NRBP family 2 | 2
STE-UNIQUE family 2 | 2
TIE family 2 | 2
TRPM2 sub-subfamily 2 | 2

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Leucine-rich repeat serine/threonine-protein kinase 1 LRRK1 Tbio Kinase -1.33128 18.1 134
Leucine-rich repeat serine/threonine-protein kinase 2 LRRK2 Tchem Kinase -3.07199 1241.4 740